Objective： To compare function recovery of left ventricle after off-pump and on-pump coronary artery bypass （OPCAB and ONCAB） using Tel index. Methods： Twenty-four patients with coronary artery disease were enroll...Objective： To compare function recovery of left ventricle after off-pump and on-pump coronary artery bypass （OPCAB and ONCAB） using Tel index. Methods： Twenty-four patients with coronary artery disease were enrolled, twelve of which received OPCAB and the others underwent ONCAB. Left ventricular ejection fraction （LVEF）, E/A ratio at mitral orifice and Tel index were measured using transthoracic echocardiography before surgery and 3-7 days, 1 month, 3 months and 6 months after surgery. Results：Tel index of both groups decreased 3-7 days after surgery, with OPCAB group＇s lower than ONCAB group＇s. The difference between pre-and post-OPCAB was significant （P〈0.01）, but not for ONCAB group （P〈0.05）. Tel index of ONCAB decreased more significant than that of OPCAB 1 month after surgery, there was statistical difference between 3-7 days and 1 month after surgery in ONCAB （P〈0.01）. Afterwards, Tel index of the 2 groups decreased steadily with no significant difference between them at other time points. LVEF and E/A ratio decreased at first, then increased gradually, with no statistical differences between the 2 groups at all time points. Conclusion： The recovery of left ventricular function after OPCAB is earlier than ONCAB. Tel index is more sensitive than LVEF and E/A ratio in detecting cardiac function recoveries and can be considered as an accurate and simple method to evaluate left ventricular systolic and diastolic function.展开更多
Objective: This prospective cohort study was designed to assess the rule of myocardial performance (Tei) index and NT-Pro BNP serum levels in prediction of weaning failure in mechanically ventilated COPD patients. Met...Objective: This prospective cohort study was designed to assess the rule of myocardial performance (Tei) index and NT-Pro BNP serum levels in prediction of weaning failure in mechanically ventilated COPD patients. Methods: Forty patients with respiratory failure due to acute exacerbation of COPD were enrolled to this study. All patients underwent a comprehensive echocardiographic examination including tissue doppler imaging within first 12 hours of admission. NT-pro BNP serum levels were measured on admission. Patients were followed up for outcome of weaning failure. Results: Right ventricular Tei index was higher in patients with failed weaning in comparison to successfully weaned patients (mean 0.66 versus 0.36, P P = 0.007). There was no difference in serum NT-Pro BNP between successfully weaned patients and patients with weaning failure. Right ventricular Tei index showed higher accuracy in predicting weaning failure than the left ventricular Tei index (AUC 0.932 versus 0.754), while serum NT-Pro BNP showed no discrimination in predicting weaning failure (AUC 0.556). Conclusion: Tei index was superior to NT-ProBNP in prediction of weaning failure in COPD patients.展开更多
Background Recent studies demonstrated that N-terminal pro-brain natriuretic peptide（NT-pro BNP） increases in patients with diabetes mellitus and raised concerns about the diagnostic validity of NT-pro BNP in assess...Background Recent studies demonstrated that N-terminal pro-brain natriuretic peptide（NT-pro BNP） increases in patients with diabetes mellitus and raised concerns about the diagnostic validity of NT-pro BNP in assessment of cardiac function in patients with hyperglycemia.Current investigation was carried out to observe the influence of hyperglycemia on the correlation of NT-pro BNP and cardiac function index in patients with acute coronary syndrome（ACS）.Methods Fifty patients with ACS were enrolled and divided into hyperglycemia group（fasting plasma glucose（FPG） ≥ 6.1 mmol/L） and euglycemia group（FPG 〈 6.1 mmol/L）.All the patients underwent routine transthoracic ecocardiagraphy and tissue Doppler imaging（TDI） investigation.Blood sample were obtained with 24 hours of hospitalization for measuring of NT-proBNP level.Relation between TDI-Tei index and the level of NT-proBNP were analyzed in the two groups respectively.Result TDI-Tei index,systolic index and diastolic index were all significantly higher in hyperglycemia group than that in euglycemia group（0.679 ± 0.139 vs 0.600 ± 0.093,P = 0.022;0.294 ± 0.074 vs 0.258 ± 0.035,P = 0.036;0.385 ± 0.069 vs 0.342 ± 0.068,P = 0.032）.TDI-Tei index was significantly negatively correlated with the level of log NT-pro BNP in both hyperglycemia group and euglycemia group（rp = 0.673,P = 0.000;rp = 0.354,P = 0.000）.Conclusions（1）Cardiac function in patients with ACS complicated with hyperglycemia is inferior to that in patients with euglycemia;（2）Assessment of cardiac function with NT-proBNP is reliable in patients with hyperglycemia.展开更多
目的探讨妊娠期糖尿病(GDM)孕妇胎儿心脏功能的变化及超声心动图Tei指数对胎儿心脏功能的评价作用。方法选取GDM孕妇108例,根据血糖控制情况分为血糖控制理想56例(GDM1组)和血糖控制不良52例(GDM2组);选取年龄、孕周及BMI相匹配的正常...目的探讨妊娠期糖尿病(GDM)孕妇胎儿心脏功能的变化及超声心动图Tei指数对胎儿心脏功能的评价作用。方法选取GDM孕妇108例,根据血糖控制情况分为血糖控制理想56例(GDM1组)和血糖控制不良52例(GDM2组);选取年龄、孕周及BMI相匹配的正常妊娠孕妇50例作为对照组。测量三组空腹血糖(FPG)、餐后2 h血糖(2 h PG)及糖化血红蛋白(GHb A_(1c))。应用多普勒超声心动图测定三组胎儿心脏结构、功能指标及左、右心室的Tei指数。结果 GDM2组FPG、2 h PG及GHb A_(1c)均高于GDM1组和对照组(P均<0.05)。GDM2组胎儿左室壁厚度、右室壁厚度、右室舒张末期内径(RVDd)、左室短轴缩短率(LVFS)、右室短轴缩短率及左室射血分数(LVEF)均高于对照组(P均<0.05),GDM2组的RVDd、右室收缩末期内径、LVFS及LVEF均高于GDM1组(P均<0.05),GDM1组LVFS高于对照组(P<0.05)。GDM1及GDM2组胎儿左、右心室Tei指数均高于对照组(P均<0.05),GDM2组胎儿左、右心室Tei指数高于GDM1组和对照组(P均<0.05)。结论 Tei指数与GDM孕妇胎儿心脏功能变化相关,可作为临床综合评估GDM胎儿心肌受累的一项简单可靠指标。展开更多
基金Supported by Scientific Technology development Foundation of Shanghai(024119028)
文摘Objective： To compare function recovery of left ventricle after off-pump and on-pump coronary artery bypass （OPCAB and ONCAB） using Tel index. Methods： Twenty-four patients with coronary artery disease were enrolled, twelve of which received OPCAB and the others underwent ONCAB. Left ventricular ejection fraction （LVEF）, E/A ratio at mitral orifice and Tel index were measured using transthoracic echocardiography before surgery and 3-7 days, 1 month, 3 months and 6 months after surgery. Results：Tel index of both groups decreased 3-7 days after surgery, with OPCAB group＇s lower than ONCAB group＇s. The difference between pre-and post-OPCAB was significant （P〈0.01）, but not for ONCAB group （P〈0.05）. Tel index of ONCAB decreased more significant than that of OPCAB 1 month after surgery, there was statistical difference between 3-7 days and 1 month after surgery in ONCAB （P〈0.01）. Afterwards, Tel index of the 2 groups decreased steadily with no significant difference between them at other time points. LVEF and E/A ratio decreased at first, then increased gradually, with no statistical differences between the 2 groups at all time points. Conclusion： The recovery of left ventricular function after OPCAB is earlier than ONCAB. Tel index is more sensitive than LVEF and E/A ratio in detecting cardiac function recoveries and can be considered as an accurate and simple method to evaluate left ventricular systolic and diastolic function.
文摘Objective: This prospective cohort study was designed to assess the rule of myocardial performance (Tei) index and NT-Pro BNP serum levels in prediction of weaning failure in mechanically ventilated COPD patients. Methods: Forty patients with respiratory failure due to acute exacerbation of COPD were enrolled to this study. All patients underwent a comprehensive echocardiographic examination including tissue doppler imaging within first 12 hours of admission. NT-pro BNP serum levels were measured on admission. Patients were followed up for outcome of weaning failure. Results: Right ventricular Tei index was higher in patients with failed weaning in comparison to successfully weaned patients (mean 0.66 versus 0.36, P P = 0.007). There was no difference in serum NT-Pro BNP between successfully weaned patients and patients with weaning failure. Right ventricular Tei index showed higher accuracy in predicting weaning failure than the left ventricular Tei index (AUC 0.932 versus 0.754), while serum NT-Pro BNP showed no discrimination in predicting weaning failure (AUC 0.556). Conclusion: Tei index was superior to NT-ProBNP in prediction of weaning failure in COPD patients.
基金supported by Science and Technology Planning Project of Guangdong Province,China (2007B031505009)
文摘Background Recent studies demonstrated that N-terminal pro-brain natriuretic peptide（NT-pro BNP） increases in patients with diabetes mellitus and raised concerns about the diagnostic validity of NT-pro BNP in assessment of cardiac function in patients with hyperglycemia.Current investigation was carried out to observe the influence of hyperglycemia on the correlation of NT-pro BNP and cardiac function index in patients with acute coronary syndrome（ACS）.Methods Fifty patients with ACS were enrolled and divided into hyperglycemia group（fasting plasma glucose（FPG） ≥ 6.1 mmol/L） and euglycemia group（FPG 〈 6.1 mmol/L）.All the patients underwent routine transthoracic ecocardiagraphy and tissue Doppler imaging（TDI） investigation.Blood sample were obtained with 24 hours of hospitalization for measuring of NT-proBNP level.Relation between TDI-Tei index and the level of NT-proBNP were analyzed in the two groups respectively.Result TDI-Tei index,systolic index and diastolic index were all significantly higher in hyperglycemia group than that in euglycemia group（0.679 ± 0.139 vs 0.600 ± 0.093,P = 0.022;0.294 ± 0.074 vs 0.258 ± 0.035,P = 0.036;0.385 ± 0.069 vs 0.342 ± 0.068,P = 0.032）.TDI-Tei index was significantly negatively correlated with the level of log NT-pro BNP in both hyperglycemia group and euglycemia group（rp = 0.673,P = 0.000;rp = 0.354,P = 0.000）.Conclusions（1）Cardiac function in patients with ACS complicated with hyperglycemia is inferior to that in patients with euglycemia;（2）Assessment of cardiac function with NT-proBNP is reliable in patients with hyperglycemia.
文摘目的探讨妊娠期糖尿病(GDM)孕妇胎儿心脏功能的变化及超声心动图Tei指数对胎儿心脏功能的评价作用。方法选取GDM孕妇108例,根据血糖控制情况分为血糖控制理想56例(GDM1组)和血糖控制不良52例(GDM2组);选取年龄、孕周及BMI相匹配的正常妊娠孕妇50例作为对照组。测量三组空腹血糖(FPG)、餐后2 h血糖(2 h PG)及糖化血红蛋白(GHb A_(1c))。应用多普勒超声心动图测定三组胎儿心脏结构、功能指标及左、右心室的Tei指数。结果 GDM2组FPG、2 h PG及GHb A_(1c)均高于GDM1组和对照组(P均<0.05)。GDM2组胎儿左室壁厚度、右室壁厚度、右室舒张末期内径(RVDd)、左室短轴缩短率(LVFS)、右室短轴缩短率及左室射血分数(LVEF)均高于对照组(P均<0.05),GDM2组的RVDd、右室收缩末期内径、LVFS及LVEF均高于GDM1组(P均<0.05),GDM1组LVFS高于对照组(P<0.05)。GDM1及GDM2组胎儿左、右心室Tei指数均高于对照组(P均<0.05),GDM2组胎儿左、右心室Tei指数高于GDM1组和对照组(P均<0.05)。结论 Tei指数与GDM孕妇胎儿心脏功能变化相关,可作为临床综合评估GDM胎儿心肌受累的一项简单可靠指标。
