To provide the supplier with the minimizum vehicle travel distance in the distribution process of goods in three situations of new customer demand,customer cancellation service,and change of customer delivery address,...To provide the supplier with the minimizum vehicle travel distance in the distribution process of goods in three situations of new customer demand,customer cancellation service,and change of customer delivery address,based on the ideas of pre-optimization and real-time optimization,a two-stage planning model of dynamic demand based vehicle routing problem with time windows was established.At the pre-optimization stage,an improved genetic algorithm was used to obtain the pre-optimized distribution route,a large-scale neighborhood search method was integrated into the mutation operation to improve the local optimization performance of the genetic algorithm,and a variety of operators were introduced to expand the search space of neighborhood solutions;At the real-time optimization stage,a periodic optimization strategy was adopted to transform a complex dynamic problem into several static problems,and four neighborhood search operators were used to quickly adjust the route.Two different scale examples were designed for experiments.It is proved that the algorithm can plan the better route,and adjust the distribution route in time under the real-time constraints.Therefore,the proposed algorithm can provide theoretical guidance for suppliers to solve the dynamic demand based vehicle routing problem.展开更多
Considering that the vehicle routing problem (VRP) with many extended features is widely used in actual life, such as multi-depot, heterogeneous types of vehicles, customer service priority and time windows etc., a ...Considering that the vehicle routing problem (VRP) with many extended features is widely used in actual life, such as multi-depot, heterogeneous types of vehicles, customer service priority and time windows etc., a mathematical model for multi-depot heterogeneous vehicle routing problem with soft time windows (MDHVRPSTW) is established. An improved ant colony optimization (IACO) is proposed for solving this model. First, MDHVRPSTW is transferred into different groups according to the nearest principle, and then the initial route is constructed by the scanning algorithm (SA). Secondly, genetic operators are introduced, and crossover probability and mutation probability are adaptively adjusted in order to improve the global search ability of the algorithm. Moreover, the smooth mechanism is used to improve the performance of the ant colony optimization (ACO). Finally, the 3-opt strategy is used to improve the local search ability. The proposed IACO was tested on three new instances that were generated randomly. The experimental results show that IACO is superior to the other three existing algorithms in terms of convergence speed and solution quality. Thus, the proposed method is effective and feasible, and the proposed model is meaningful.展开更多
The time dependent vehicle routing problem with time windows(TDVRPTW) is considered. A multi-type ant system(MTAS) algorithm hybridized with the ant colony system(ACS)and the max-min ant system(MMAS) algorithm...The time dependent vehicle routing problem with time windows(TDVRPTW) is considered. A multi-type ant system(MTAS) algorithm hybridized with the ant colony system(ACS)and the max-min ant system(MMAS) algorithms is proposed. This combination absorbs the merits of the two algorithms in solutions construction and optimization separately. In order to improve the efficiency of the insertion procedure, a nearest neighbor selection(NNS) mechanism, an insertion local search procedure and a local optimization procedure are specified in detail. And in order to find a balance between good scouting performance and fast convergence rate, an adaptive pheromone updating strategy is proposed in the MTAS. Computational results confirm the MTAS algorithm's good performance with all these strategies on classic vehicle routing problem with time windows(VRPTW) benchmark instances and the TDVRPTW instances, and some better results especially for the number of vehicles and travel times of the best solutions are obtained in comparison with the previous research.展开更多
The multitrip pickup and delivery problem with time windows and manpower planning(MTPDPTW-MP)determines a set of ambulance routes and finds staff assignment for a hospital. It involves different stakeholders with dive...The multitrip pickup and delivery problem with time windows and manpower planning(MTPDPTW-MP)determines a set of ambulance routes and finds staff assignment for a hospital. It involves different stakeholders with diverse interests and objectives. This study firstly introduces a multiobjective MTPDPTW-MP(MO-MTPDPTWMP) with three objectives to better describe the real-world scenario. A multiobjective iterated local search algorithm with adaptive neighborhood selection(MOILS-ANS) is proposed to solve the problem. MOILS-ANS can generate a diverse set of alternative solutions for decision makers to meet their requirements. To better explore the search space, problem-specific neighborhood structures and an adaptive neighborhood selection strategy are carefully designed in MOILS-ANS. Experimental results show that the proposed MOILS-ANS significantly outperforms the other two multiobjective algorithms. Besides, the nature of objective functions and the properties of the problem are analyzed. Finally, the proposed MOILS-ANS is compared with the previous single-objective algorithm and the benefits of multiobjective optimization are discussed.展开更多
Unmanned combat air vehicles(UCAVs) mission planning is a fairly complicated global optimum problem. Military attack missions often employ a fleet of UCAVs equipped with weapons to attack a set of known targets. A UCA...Unmanned combat air vehicles(UCAVs) mission planning is a fairly complicated global optimum problem. Military attack missions often employ a fleet of UCAVs equipped with weapons to attack a set of known targets. A UCAV can carry different weapons to accomplish different combat missions. Choice of different weapons will have different effects on the final combat effectiveness. This work presents a mixed integer programming model for simultaneous weapon configuration and route planning of UCAVs, which solves the problem optimally using the IBM ILOG CPLEX optimizer for simple missions. This paper develops a heuristic algorithm to handle the medium-scale and large-scale problems. The experiments demonstrate the performance of the heuristic algorithm in solving the medium scale and large scale problems. Moreover, we give suggestions on how to select the most appropriate algorithm to solve different scale problems.展开更多
As a new variant of vehicle routing problem( VRP),a finished vehicle routing problem with time windows in finished vehicle logistics( FVRPTW) is modeled and solved. An optimization model for FVRPTW is presented with t...As a new variant of vehicle routing problem( VRP),a finished vehicle routing problem with time windows in finished vehicle logistics( FVRPTW) is modeled and solved. An optimization model for FVRPTW is presented with the objective of scheduling multiple transport routes considering loading constraints along with time penalty function to minimize the total cost. Then a genetic algorithm( GA) is developed. The specific encoding and genetic operators for FVRPTW are devised.Especially,in order to accelerate its convergence,an improved termination condition is given. Finally,a case study is used to evaluate the effectiveness of the proposed algorithm and a series of experiments are conducted over a set of finished vehicle routing problems. The results demonstrate that the proposed approach has superior performance and satisfies users in practice. Contributions of the study are the modeling and solving of a complex FVRPTW in logistics industry.展开更多
With the expansion of the application scope of social computing problems,many path problems in real life have evolved from pure path optimization problems to social computing problems that take into account various so...With the expansion of the application scope of social computing problems,many path problems in real life have evolved from pure path optimization problems to social computing problems that take into account various social attributes,cultures,and the emotional needs of customers.The actual soft time window vehicle routing problem,speeding up the response of customer needs,improving distribution efficiency,and reducing operating costs is the focus of current social computing problems.Therefore,designing fast and effective algorithms to solve this problem has certain theoretical and practical significance.In this paper,considering the time delay problem of customer demand,the compensation problem is given,and the mathematical model of vehicle path problem with soft time window is given.This paper proposes a hybrid tabu search(TS)&scatter search(SS)algorithm for vehicle routing problem with soft time windows(VRPSTW),which mainly embeds the TS dynamic tabu mechanism into the SS algorithm framework.TS uses the scattering of SS to avoid the dependence on the quality of the initial solution,and SS uses the climbing ability of TS improves the ability of optimizing,so that the quality of search for the optimal solution can be significantly improved.The hybrid algorithm is still based on the basic framework of SS.In particular,TS is mainly used for solution improvement and combination to generate new solutions.In the solution process,both the quality and the dispersion of the solution are considered.A simulation experiments verify the influence of the number of vehicles and maximum value of tabu length on solution,parameters’control over the degree of convergence,and the influence of the number of diverse solutions on algorithm performance.Based on the determined parameters,simulation experiment is carried out in this paper to further prove the algorithm feasibility and effectiveness.The results of this paper provide further ideas for solving vehicle routing problems with time windows and improving the efficiency of vehicle routing problems and have strong applicability.展开更多
The scheduling efficiency of the tracking and data relay satellite system(TDRSS)is strictly limited by the scheduling degrees of freedom(DoF),including time DoF defined by jobs' flexible time windows and spatial ...The scheduling efficiency of the tracking and data relay satellite system(TDRSS)is strictly limited by the scheduling degrees of freedom(DoF),including time DoF defined by jobs' flexible time windows and spatial DoF brought by multiple servable tracking and data relay satellites(TDRSs).In this paper,ageneralized multiple time windows(GMTW)model is proposed to fully exploit the time and spatial DoF.Then,the improvements of service capability and job-completion probability based on the GMTW are theoretically proved.Further,an asymmetric path-relinking(APR)based heuristic job scheduling framework is presented to maximize the usage of DoF provided by the GMTW.Simulation results show that by using our proposal 11%improvement of average jobcompletion probability can be obtained.Meanwhile,the computing time of the time-to-target can be shorten to 1/9 of the GRASP.展开更多
This study attempts to solve vehicle routing problem with time window (VRPTW). The study first identifies the real problems and suggests some recommendations on the issues. The technique used in this study is Genetic ...This study attempts to solve vehicle routing problem with time window (VRPTW). The study first identifies the real problems and suggests some recommendations on the issues. The technique used in this study is Genetic Algorithm (GA) and initialization applied is random population method. The objective of the study is to assign a number of vehicles to routes that connect customers and depot such that the overall distance travelled is minimized and the delivery operations are completed within the time windows requested by the customers. The analysis reveals that the problems experienced in vehicle routing with time window can be solved by GA and retrieved for optimal solutions. After a thorough study on VRPTW, it is highly recommended that a company should implement the optimal routes derived from the study to increase the efficiency and accuracy of delivery with time insertion.展开更多
A novel genetic algorithm with multiple species in dynamic region is proposed,each of which occupies a dynamic region determined by the weight vector of a fuzzy adaptive Hamming neural network. Through learning and cl...A novel genetic algorithm with multiple species in dynamic region is proposed,each of which occupies a dynamic region determined by the weight vector of a fuzzy adaptive Hamming neural network. Through learning and classification of genetic individuals in the evolutionary procedure,the neural network distributes multiple species into different regions of the search space. Furthermore,the neural network dynamically expands each search region or establishes new region for good offspring individuals to continuously keep the diversification of the genetic population. As a result,the premature problem inherent in genetic algorithm is alleviated and better tradeoff between the ability of exploration and exploitation can be obtained. The experimental results on the vehicle routing problem with time windows also show the good performance of the proposed genetic algorithm.展开更多
Our research focuses on the development of two cooperative approaches for resolution of the multi-item capacitated lot-sizing problems with time windows and setup times (MICLSP-TW-ST). In this paper we combine variabl...Our research focuses on the development of two cooperative approaches for resolution of the multi-item capacitated lot-sizing problems with time windows and setup times (MICLSP-TW-ST). In this paper we combine variable neighborhood search and accurate mixed integer programming (VNS-MIP) to solve MICLSP-TW-ST. It concerns so a particularly important and difficult problem in production planning. This problem is NP-hard in the strong sense. Moreover, it is very difficult to solve with an exact method;it is for that reason we have made use of the approximate methods. We improved the variable neighborhood search (VNS) algorithm, which is efficient for solving hard combinatorial optimization problems. This problem can be viewed as an optimization problem with mixed variables (binary variables and real variables). The new VNS algorithm was tested against 540 benchmark problems. The performance of most of our approaches was satisfactory and performed better than the algorithms already proposed in the literature.展开更多
The main objective of this paper is to propose a two-phase solution algorithm for solving the Inventory Routing Problem with Time Windows (IRPTW), which has not been excessively researched in the literature. The sol...The main objective of this paper is to propose a two-phase solution algorithm for solving the Inventory Routing Problem with Time Windows (IRPTW), which has not been excessively researched in the literature. The solution approach is based on (a) a simple simulation for the planning phase (Phase I) and (b) the Variable Neighborhood Search Algorithm (VNS) for the routing phase (Phase II). Testing instances are established to investigate algorithmic performance, and the computational results are then reported. The computational study underscores the importance of integrating the inventory and vehicle routing decisions. Graphical presentation formats are provided to convey meaningful insights into the problem.展开更多
Consensus of creativity research suggests that the measurement of both originality and valuableness is necessary when designing creativity tasks.However,few studies have emphasized valuableness when exploring underlyi...Consensus of creativity research suggests that the measurement of both originality and valuableness is necessary when designing creativity tasks.However,few studies have emphasized valuableness when exploring underlying neural substrates of creative thinking.The present study employs product-based creativity tasks that measure both originality and valuableness in an exploration of the dynamic relationship between the default mode(DMN),executive control(ECN),and salience(SN)networks through time windows.This methodology highlights relevance,or valuableness,in creativity evaluation as opposed to divergent thinking tasks solely measuring originality.The researchers identified seven brain regions belonging to the ECN,DMN,and SN as regions of interest(ROIs),as well as four representative seeds to analyze functional connectivity in 25 college student participants.Results showed that all of the identified ROIs were involved during the creative task.The insula,precuneus,and ventrolateral prefrontal cortex(vlPFC)remained active across all stages of product-based creative thinking.Moreover,the connectivity analyses revealed varied interaction patterns of DMN,ECN,and SN at different thinking stages.The integrated findings of the whole brain,ROI,and connectivity analyses suggest a trend that the DMN and SN(which relate to bottom-up thinking)attenuate as time proceeds,whereas the vlPFC(which relates to top-down thinking)gets stronger at later stages;these findings reflect the nature of our creativity tasks and decision-making of valuableness in later stages.Based on brain region activation throughout execution of the task,we propose that product-based creative process may include three stages:exploration and association,incubation and insight,and finally,evaluation and decision making.This model provides a thinking frame for further research and classroom instruction.展开更多
The hybrid flow shop group scheduling problem(HFGSP)with the delivery time windows has been widely studied owing to its better flexibility and suitability for the current just-in-time production mode.However,there are...The hybrid flow shop group scheduling problem(HFGSP)with the delivery time windows has been widely studied owing to its better flexibility and suitability for the current just-in-time production mode.However,there are several unresolved challenges in problem modeling and algorithmic design tailored for HFGSP.In our study,we place emphasis on the constraint of timeliness.Therefore,this paper first constructs a mixed integer linear programming model of HFGSP with sequence-dependent setup time and delivery time windows to minimize the total weighted earliness and tardiness(TWET).Then a penalty groups-assisted iterated greedy integrating idle time insertion(PG IG ITI)is proposed to solve the above problem.In the PG IG ITI,a double decoding strategy is proposed based on the earliest available machine rule and the idle time insertion rule to calculate the TWET value.Subsequently,to reduce the amount of computation,a skip-based destruction and reconstruction strategy is designed,and a penalty groups-assisted local search is proposed to further improve the quality of the solution by disturbing the penalized groups,i.e.,early and tardy groups.Finally,through comprehensive statistical experiments on 270 test instances,the results prove that the proposed algorithm is effective compared to four state-of-the-art algorithms.展开更多
The Vehicle Routing Problem with Time Windows is a generalization of the well knowncapacity constrained Vehicle Routing Problem.A homogeneous fleet of vehicles has to service a setof customers.The service of the custo...The Vehicle Routing Problem with Time Windows is a generalization of the well knowncapacity constrained Vehicle Routing Problem.A homogeneous fleet of vehicles has to service a setof customers.The service of the customers can only start within a weU-defined time intervaldenoted the time window.The objective is to determine routes for the vehicles that minimizes theaccumulated cost(or distance).Currently the best approaches for determining optimal solutions arebased on column generation and Branch-and-Bound,also known as Branch-and-Price.This paperpresents two ideas for ran-time improvements of the Branch-and-Price framework for the VehicleRouting Problem with Time Windows.Both ideas reveal a significant potential for run-timerefinements when speeding up an exact approach without compromising optimality.展开更多
Vehicle routing problem with time windows(VRPTW)is a core combinatorial optimization problem in distribution tasks.The electric vehicle routing problem with time windows under demand uncertainty and weight-related ene...Vehicle routing problem with time windows(VRPTW)is a core combinatorial optimization problem in distribution tasks.The electric vehicle routing problem with time windows under demand uncertainty and weight-related energy consumption is an extension of the VRPTW.Although some researchers have studied either the electric VRPTW with nonlinear energy consumption model or the impact of the uncertain customer demand on the conventional vehicles,the literature on the integration of uncertain demand and energy consumption of electric vehicles is still scarce.However,practically,it is usually not feasible to ignore the uncertainty of customer demand and the weight-related energy consumption of electronic vehicles(EVs)in actual operation.Hence,we propose the robust optimization model based on a route-related uncertain set to tackle this problem.Moreover,adaptive large neighbourhood search heuristic has been developed to solve the problem due to the NP-hard nature of the problem.The effectiveness of the method is verified by experiments,and the influence of uncertain demand and uncertain parameters on the solution is further explored.展开更多
The vehicle routing problem with time windows (VRPTW) involves assigning a fleet of limited capacity vehicles to serve a set of customers without violating the capacity and time constraints. This paper presents a mu...The vehicle routing problem with time windows (VRPTW) involves assigning a fleet of limited capacity vehicles to serve a set of customers without violating the capacity and time constraints. This paper presents a multi-agent model system for the VRPTW based on the internal behavior of agents and coordination among the agents. The system presents a formal view of coordination using the traditional contract-net protocol (CNP) that relies on the basic loop of agent behavior for order receiving, order announcement, bid calculation, and order scheduling followed by order execution. An improved CNP method based on a vehicle selection strategy is used to reduce the number of negotiations and the negotiation time. The model is validated using Solomon's benchmarks, with the results showing that the improved CNP uses only 30% as many negotiations and only 70% of the negotiation time of the traditional CNP.展开更多
Objective To evaluate the utility of computed tomography perfusion(CTP)both at admission and during delayed cerebral ischemia time-window(DCITW)in the detection of delayed cerebral ischemia(DCI)and the change in CTP p...Objective To evaluate the utility of computed tomography perfusion(CTP)both at admission and during delayed cerebral ischemia time-window(DCITW)in the detection of delayed cerebral ischemia(DCI)and the change in CTP parameters from admission to DCITW following aneurysmal subarachnoid hemorrhage.Methods Eighty patients underwent CTP at admission and during DCITW.The mean and extreme values of all CTP parameters at admission and during DCITW were compared between the DCI group and non-DCI group,and comparisons were also made between admission and DCITW within each group.The qualitative color-coded perfusion maps were recorded.Finally,the relationship between CTP parameters and DCI was assessed by receiver operating characteristic(ROC)analyses.Results With the exception of cerebral blood volume(P=0.295,admission;P=0.682,DCITW),there were significant differences in the mean quantitative CTP parameters between DCI and non-DCI patients both at admission and during DCITW.In the DCI group,the extreme parameters were significantly different between admission and DCITW.The DCI group also showed a deteriorative trend in the qualitative color-coded perfusion maps.For the detection of DCI,mean transit time to the center of the impulse response function(Tmax)at admission and mean time to start(TTS)during DCITW had the largest area under curve(AUC),0.698 and 0.789,respectively.Conclusion Whole-brain CTP can predict the occurrence of DCI at admission and diagnose DCI during DCITW.The extreme quantitative parameters and qualitative color-coded perfusion maps can better reflect the perfusion changes of patients with DCI from admission to DCITW.展开更多
This study aimed to identify the optimal neural progenitor cell transplantation time for spinal cord injury in rats via the subarachnoid space. Cultured neural progenitor cells from 14-day embryonic rats, constitutive...This study aimed to identify the optimal neural progenitor cell transplantation time for spinal cord injury in rats via the subarachnoid space. Cultured neural progenitor cells from 14-day embryonic rats, constitutively expressing enhanced green fluorescence protein, or media alone, were injected into the subarachnoid space of adult rats at 1 hour (acute stage), 7 days (subacute stage) and 28 days (chronic stage) after contusive spinal cord injury. Results showed that grafted neural progenitor cells migrated and aggregated around the blood vessels of the injured region, and infiltrated the spinal cord parenchyma along the tissue spaces in the acute stage transplantation group. However, this was not observed in subacute and chronic stage transplantation groups. 04- and glial fibrillary acidic protein-positive cells, representing oligodendrocytes and astrocytes respectively, were detected in the core of the grafted cluster attached to the cauda equina pia surface in the chronic stage transplantation group 8 weeks after transplantation. Both acute and subacute stage transplantation groups were negative for 04 and glial fibrillary acidic protein cells. Basso, Beattie and Bresnahan scale score comparisons indicated that rat hind limb locomotor activity showed better recovery after acute stage transplantation than after subacute and chronic transplantation. Our experimental findings suggest that the subarachnoid route could be useful for transplantation of neural progenitor cells at the acute stage of spinal cord injury. Although grafted cells survived only for a short time and did not differentiate into astrocytes or neurons, they were able to reach the parenchyma of the injured spinal cord and improve neurological function in rats. Transplantation efficacy was enhanced at the acute stage in comparison with subacute and chronic stages.展开更多
A preliminary study from our research group showed that picroside II inhibited neuronal apop- tosis in ischemic penumbra, reduced ischemic volume, and improved neurobehavioral function in rats with cerebral ischemia. ...A preliminary study from our research group showed that picroside II inhibited neuronal apop- tosis in ischemic penumbra, reduced ischemic volume, and improved neurobehavioral function in rats with cerebral ischemia. The aim of the present study was to validate the neuroprotective effects of picroside II and optimize its therapeutic time window and dose in a rat model of cerebral ischemia. We found that picroside Ⅱ inhibited cell apoptosis and reduced the expression of neuron-specific enolase, a marker of neuronal damage, in rats after cerebral ischemic injury. The optimal treatment time after ischemic injury and dose were determined, respectively, as follows: (1) 2.0 hours and 10 mg/kg according to the results of toluidine blue staining; (2) 1.5 hours and 10 mg/kg according to early apoptotic ratio by flow cytometry; (3) 2.0 hours and 10 mg/kg according to immunohistochemical and western blot analysis; and (4) 1.5 hours and 10 mg/kg according to reverse transcription polymerase chain reaction. The present findings suggest that an intraperitoneal injection of 10 mg/kg picroside II 1.5-2.0 hours after cerebral ischemic injury in rats is the optimal dose and time for therapeutic benefit.展开更多
基金supported by Natural Science Foundation Project of Gansu Provincial Science and Technology Department(No.1506RJZA084)Gansu Provincial Education Department Scientific Research Fund Grant Project(No.1204-13).
文摘To provide the supplier with the minimizum vehicle travel distance in the distribution process of goods in three situations of new customer demand,customer cancellation service,and change of customer delivery address,based on the ideas of pre-optimization and real-time optimization,a two-stage planning model of dynamic demand based vehicle routing problem with time windows was established.At the pre-optimization stage,an improved genetic algorithm was used to obtain the pre-optimized distribution route,a large-scale neighborhood search method was integrated into the mutation operation to improve the local optimization performance of the genetic algorithm,and a variety of operators were introduced to expand the search space of neighborhood solutions;At the real-time optimization stage,a periodic optimization strategy was adopted to transform a complex dynamic problem into several static problems,and four neighborhood search operators were used to quickly adjust the route.Two different scale examples were designed for experiments.It is proved that the algorithm can plan the better route,and adjust the distribution route in time under the real-time constraints.Therefore,the proposed algorithm can provide theoretical guidance for suppliers to solve the dynamic demand based vehicle routing problem.
基金The National Natural Science Foundation of China(No.61074147)the Natural Science Foundation of Guangdong Province(No.S2011010005059)+2 种基金the Foundation of Enterprise-University-Research Institute Cooperation from Guangdong Province and Ministry of Education of China(No.2012B091000171,2011B090400460)the Science and Technology Program of Guangdong Province(No.2012B050600028)the Science and Technology Program of Huadu District,Guangzhou(No.HD14ZD001)
文摘Considering that the vehicle routing problem (VRP) with many extended features is widely used in actual life, such as multi-depot, heterogeneous types of vehicles, customer service priority and time windows etc., a mathematical model for multi-depot heterogeneous vehicle routing problem with soft time windows (MDHVRPSTW) is established. An improved ant colony optimization (IACO) is proposed for solving this model. First, MDHVRPSTW is transferred into different groups according to the nearest principle, and then the initial route is constructed by the scanning algorithm (SA). Secondly, genetic operators are introduced, and crossover probability and mutation probability are adaptively adjusted in order to improve the global search ability of the algorithm. Moreover, the smooth mechanism is used to improve the performance of the ant colony optimization (ACO). Finally, the 3-opt strategy is used to improve the local search ability. The proposed IACO was tested on three new instances that were generated randomly. The experimental results show that IACO is superior to the other three existing algorithms in terms of convergence speed and solution quality. Thus, the proposed method is effective and feasible, and the proposed model is meaningful.
文摘The time dependent vehicle routing problem with time windows(TDVRPTW) is considered. A multi-type ant system(MTAS) algorithm hybridized with the ant colony system(ACS)and the max-min ant system(MMAS) algorithms is proposed. This combination absorbs the merits of the two algorithms in solutions construction and optimization separately. In order to improve the efficiency of the insertion procedure, a nearest neighbor selection(NNS) mechanism, an insertion local search procedure and a local optimization procedure are specified in detail. And in order to find a balance between good scouting performance and fast convergence rate, an adaptive pheromone updating strategy is proposed in the MTAS. Computational results confirm the MTAS algorithm's good performance with all these strategies on classic vehicle routing problem with time windows(VRPTW) benchmark instances and the TDVRPTW instances, and some better results especially for the number of vehicles and travel times of the best solutions are obtained in comparison with the previous research.
基金supported by the National Key R&D Program of China(2018AAA0101203)the National Natural Science Foundation of China(61673403,71601191)the JSPS KAKENHI(JP17K12751)。
文摘The multitrip pickup and delivery problem with time windows and manpower planning(MTPDPTW-MP)determines a set of ambulance routes and finds staff assignment for a hospital. It involves different stakeholders with diverse interests and objectives. This study firstly introduces a multiobjective MTPDPTW-MP(MO-MTPDPTWMP) with three objectives to better describe the real-world scenario. A multiobjective iterated local search algorithm with adaptive neighborhood selection(MOILS-ANS) is proposed to solve the problem. MOILS-ANS can generate a diverse set of alternative solutions for decision makers to meet their requirements. To better explore the search space, problem-specific neighborhood structures and an adaptive neighborhood selection strategy are carefully designed in MOILS-ANS. Experimental results show that the proposed MOILS-ANS significantly outperforms the other two multiobjective algorithms. Besides, the nature of objective functions and the properties of the problem are analyzed. Finally, the proposed MOILS-ANS is compared with the previous single-objective algorithm and the benefits of multiobjective optimization are discussed.
基金supported by the National Natural Science Foundation of China(7147117571471174)
文摘Unmanned combat air vehicles(UCAVs) mission planning is a fairly complicated global optimum problem. Military attack missions often employ a fleet of UCAVs equipped with weapons to attack a set of known targets. A UCAV can carry different weapons to accomplish different combat missions. Choice of different weapons will have different effects on the final combat effectiveness. This work presents a mixed integer programming model for simultaneous weapon configuration and route planning of UCAVs, which solves the problem optimally using the IBM ILOG CPLEX optimizer for simple missions. This paper develops a heuristic algorithm to handle the medium-scale and large-scale problems. The experiments demonstrate the performance of the heuristic algorithm in solving the medium scale and large scale problems. Moreover, we give suggestions on how to select the most appropriate algorithm to solve different scale problems.
基金Supported by the National Natural Science Foundation of China(No.51565036)
文摘As a new variant of vehicle routing problem( VRP),a finished vehicle routing problem with time windows in finished vehicle logistics( FVRPTW) is modeled and solved. An optimization model for FVRPTW is presented with the objective of scheduling multiple transport routes considering loading constraints along with time penalty function to minimize the total cost. Then a genetic algorithm( GA) is developed. The specific encoding and genetic operators for FVRPTW are devised.Especially,in order to accelerate its convergence,an improved termination condition is given. Finally,a case study is used to evaluate the effectiveness of the proposed algorithm and a series of experiments are conducted over a set of finished vehicle routing problems. The results demonstrate that the proposed approach has superior performance and satisfies users in practice. Contributions of the study are the modeling and solving of a complex FVRPTW in logistics industry.
基金This work was supported by the National Natural Science Foundation of China(61772196,61472136)the Hunan Provincial Focus Social Science Fund(2016ZDB006)Thanks to Professor Weijin Jiang for his guidance and suggestions on this research.Funding Statement。
文摘With the expansion of the application scope of social computing problems,many path problems in real life have evolved from pure path optimization problems to social computing problems that take into account various social attributes,cultures,and the emotional needs of customers.The actual soft time window vehicle routing problem,speeding up the response of customer needs,improving distribution efficiency,and reducing operating costs is the focus of current social computing problems.Therefore,designing fast and effective algorithms to solve this problem has certain theoretical and practical significance.In this paper,considering the time delay problem of customer demand,the compensation problem is given,and the mathematical model of vehicle path problem with soft time window is given.This paper proposes a hybrid tabu search(TS)&scatter search(SS)algorithm for vehicle routing problem with soft time windows(VRPSTW),which mainly embeds the TS dynamic tabu mechanism into the SS algorithm framework.TS uses the scattering of SS to avoid the dependence on the quality of the initial solution,and SS uses the climbing ability of TS improves the ability of optimizing,so that the quality of search for the optimal solution can be significantly improved.The hybrid algorithm is still based on the basic framework of SS.In particular,TS is mainly used for solution improvement and combination to generate new solutions.In the solution process,both the quality and the dispersion of the solution are considered.A simulation experiments verify the influence of the number of vehicles and maximum value of tabu length on solution,parameters’control over the degree of convergence,and the influence of the number of diverse solutions on algorithm performance.Based on the determined parameters,simulation experiment is carried out in this paper to further prove the algorithm feasibility and effectiveness.The results of this paper provide further ideas for solving vehicle routing problems with time windows and improving the efficiency of vehicle routing problems and have strong applicability.
基金Supported by the National Natural Science Foundation of China(91338101,91338108,61132002,6132106)Research Fund of Tsinghua University(2011Z05117)Co-innovation Laboratory of Aerospace Broadband Network Technology
文摘The scheduling efficiency of the tracking and data relay satellite system(TDRSS)is strictly limited by the scheduling degrees of freedom(DoF),including time DoF defined by jobs' flexible time windows and spatial DoF brought by multiple servable tracking and data relay satellites(TDRSs).In this paper,ageneralized multiple time windows(GMTW)model is proposed to fully exploit the time and spatial DoF.Then,the improvements of service capability and job-completion probability based on the GMTW are theoretically proved.Further,an asymmetric path-relinking(APR)based heuristic job scheduling framework is presented to maximize the usage of DoF provided by the GMTW.Simulation results show that by using our proposal 11%improvement of average jobcompletion probability can be obtained.Meanwhile,the computing time of the time-to-target can be shorten to 1/9 of the GRASP.
文摘This study attempts to solve vehicle routing problem with time window (VRPTW). The study first identifies the real problems and suggests some recommendations on the issues. The technique used in this study is Genetic Algorithm (GA) and initialization applied is random population method. The objective of the study is to assign a number of vehicles to routes that connect customers and depot such that the overall distance travelled is minimized and the delivery operations are completed within the time windows requested by the customers. The analysis reveals that the problems experienced in vehicle routing with time window can be solved by GA and retrieved for optimal solutions. After a thorough study on VRPTW, it is highly recommended that a company should implement the optimal routes derived from the study to increase the efficiency and accuracy of delivery with time insertion.
文摘A novel genetic algorithm with multiple species in dynamic region is proposed,each of which occupies a dynamic region determined by the weight vector of a fuzzy adaptive Hamming neural network. Through learning and classification of genetic individuals in the evolutionary procedure,the neural network distributes multiple species into different regions of the search space. Furthermore,the neural network dynamically expands each search region or establishes new region for good offspring individuals to continuously keep the diversification of the genetic population. As a result,the premature problem inherent in genetic algorithm is alleviated and better tradeoff between the ability of exploration and exploitation can be obtained. The experimental results on the vehicle routing problem with time windows also show the good performance of the proposed genetic algorithm.
文摘Our research focuses on the development of two cooperative approaches for resolution of the multi-item capacitated lot-sizing problems with time windows and setup times (MICLSP-TW-ST). In this paper we combine variable neighborhood search and accurate mixed integer programming (VNS-MIP) to solve MICLSP-TW-ST. It concerns so a particularly important and difficult problem in production planning. This problem is NP-hard in the strong sense. Moreover, it is very difficult to solve with an exact method;it is for that reason we have made use of the approximate methods. We improved the variable neighborhood search (VNS) algorithm, which is efficient for solving hard combinatorial optimization problems. This problem can be viewed as an optimization problem with mixed variables (binary variables and real variables). The new VNS algorithm was tested against 540 benchmark problems. The performance of most of our approaches was satisfactory and performed better than the algorithms already proposed in the literature.
文摘The main objective of this paper is to propose a two-phase solution algorithm for solving the Inventory Routing Problem with Time Windows (IRPTW), which has not been excessively researched in the literature. The solution approach is based on (a) a simple simulation for the planning phase (Phase I) and (b) the Variable Neighborhood Search Algorithm (VNS) for the routing phase (Phase II). Testing instances are established to investigate algorithmic performance, and the computational results are then reported. The computational study underscores the importance of integrating the inventory and vehicle routing decisions. Graphical presentation formats are provided to convey meaningful insights into the problem.
文摘Consensus of creativity research suggests that the measurement of both originality and valuableness is necessary when designing creativity tasks.However,few studies have emphasized valuableness when exploring underlying neural substrates of creative thinking.The present study employs product-based creativity tasks that measure both originality and valuableness in an exploration of the dynamic relationship between the default mode(DMN),executive control(ECN),and salience(SN)networks through time windows.This methodology highlights relevance,or valuableness,in creativity evaluation as opposed to divergent thinking tasks solely measuring originality.The researchers identified seven brain regions belonging to the ECN,DMN,and SN as regions of interest(ROIs),as well as four representative seeds to analyze functional connectivity in 25 college student participants.Results showed that all of the identified ROIs were involved during the creative task.The insula,precuneus,and ventrolateral prefrontal cortex(vlPFC)remained active across all stages of product-based creative thinking.Moreover,the connectivity analyses revealed varied interaction patterns of DMN,ECN,and SN at different thinking stages.The integrated findings of the whole brain,ROI,and connectivity analyses suggest a trend that the DMN and SN(which relate to bottom-up thinking)attenuate as time proceeds,whereas the vlPFC(which relates to top-down thinking)gets stronger at later stages;these findings reflect the nature of our creativity tasks and decision-making of valuableness in later stages.Based on brain region activation throughout execution of the task,we propose that product-based creative process may include three stages:exploration and association,incubation and insight,and finally,evaluation and decision making.This model provides a thinking frame for further research and classroom instruction.
基金This work was supported by the Natural Science Foundation of Shandong province(No.ZR2023MF022)National Natural Science Foundation of China(Nos.61973203,61803192,62106073,and 61966012)Guangyue Young Scholar Innovation Team of Liaocheng University(No.LCUGYTD2022-03).
文摘The hybrid flow shop group scheduling problem(HFGSP)with the delivery time windows has been widely studied owing to its better flexibility and suitability for the current just-in-time production mode.However,there are several unresolved challenges in problem modeling and algorithmic design tailored for HFGSP.In our study,we place emphasis on the constraint of timeliness.Therefore,this paper first constructs a mixed integer linear programming model of HFGSP with sequence-dependent setup time and delivery time windows to minimize the total weighted earliness and tardiness(TWET).Then a penalty groups-assisted iterated greedy integrating idle time insertion(PG IG ITI)is proposed to solve the above problem.In the PG IG ITI,a double decoding strategy is proposed based on the earliest available machine rule and the idle time insertion rule to calculate the TWET value.Subsequently,to reduce the amount of computation,a skip-based destruction and reconstruction strategy is designed,and a penalty groups-assisted local search is proposed to further improve the quality of the solution by disturbing the penalized groups,i.e.,early and tardy groups.Finally,through comprehensive statistical experiments on 270 test instances,the results prove that the proposed algorithm is effective compared to four state-of-the-art algorithms.
文摘The Vehicle Routing Problem with Time Windows is a generalization of the well knowncapacity constrained Vehicle Routing Problem.A homogeneous fleet of vehicles has to service a setof customers.The service of the customers can only start within a weU-defined time intervaldenoted the time window.The objective is to determine routes for the vehicles that minimizes theaccumulated cost(or distance).Currently the best approaches for determining optimal solutions arebased on column generation and Branch-and-Bound,also known as Branch-and-Price.This paperpresents two ideas for ran-time improvements of the Branch-and-Price framework for the VehicleRouting Problem with Time Windows.Both ideas reveal a significant potential for run-timerefinements when speeding up an exact approach without compromising optimality.
文摘Vehicle routing problem with time windows(VRPTW)is a core combinatorial optimization problem in distribution tasks.The electric vehicle routing problem with time windows under demand uncertainty and weight-related energy consumption is an extension of the VRPTW.Although some researchers have studied either the electric VRPTW with nonlinear energy consumption model or the impact of the uncertain customer demand on the conventional vehicles,the literature on the integration of uncertain demand and energy consumption of electric vehicles is still scarce.However,practically,it is usually not feasible to ignore the uncertainty of customer demand and the weight-related energy consumption of electronic vehicles(EVs)in actual operation.Hence,we propose the robust optimization model based on a route-related uncertain set to tackle this problem.Moreover,adaptive large neighbourhood search heuristic has been developed to solve the problem due to the NP-hard nature of the problem.The effectiveness of the method is verified by experiments,and the influence of uncertain demand and uncertain parameters on the solution is further explored.
文摘The vehicle routing problem with time windows (VRPTW) involves assigning a fleet of limited capacity vehicles to serve a set of customers without violating the capacity and time constraints. This paper presents a multi-agent model system for the VRPTW based on the internal behavior of agents and coordination among the agents. The system presents a formal view of coordination using the traditional contract-net protocol (CNP) that relies on the basic loop of agent behavior for order receiving, order announcement, bid calculation, and order scheduling followed by order execution. An improved CNP method based on a vehicle selection strategy is used to reduce the number of negotiations and the negotiation time. The model is validated using Solomon's benchmarks, with the results showing that the improved CNP uses only 30% as many negotiations and only 70% of the negotiation time of the traditional CNP.
基金supported by the National Natural Science Foundation of China,Research on Brain Magnetic Resonance Image Segmentation Based on Particle Computation(No.61672386).
文摘Objective To evaluate the utility of computed tomography perfusion(CTP)both at admission and during delayed cerebral ischemia time-window(DCITW)in the detection of delayed cerebral ischemia(DCI)and the change in CTP parameters from admission to DCITW following aneurysmal subarachnoid hemorrhage.Methods Eighty patients underwent CTP at admission and during DCITW.The mean and extreme values of all CTP parameters at admission and during DCITW were compared between the DCI group and non-DCI group,and comparisons were also made between admission and DCITW within each group.The qualitative color-coded perfusion maps were recorded.Finally,the relationship between CTP parameters and DCI was assessed by receiver operating characteristic(ROC)analyses.Results With the exception of cerebral blood volume(P=0.295,admission;P=0.682,DCITW),there were significant differences in the mean quantitative CTP parameters between DCI and non-DCI patients both at admission and during DCITW.In the DCI group,the extreme parameters were significantly different between admission and DCITW.The DCI group also showed a deteriorative trend in the qualitative color-coded perfusion maps.For the detection of DCI,mean transit time to the center of the impulse response function(Tmax)at admission and mean time to start(TTS)during DCITW had the largest area under curve(AUC),0.698 and 0.789,respectively.Conclusion Whole-brain CTP can predict the occurrence of DCI at admission and diagnose DCI during DCITW.The extreme quantitative parameters and qualitative color-coded perfusion maps can better reflect the perfusion changes of patients with DCI from admission to DCITW.
基金supported by the People’s Liberation Army Fund for Special Projects of Medical Sciences, No. 06G114
文摘This study aimed to identify the optimal neural progenitor cell transplantation time for spinal cord injury in rats via the subarachnoid space. Cultured neural progenitor cells from 14-day embryonic rats, constitutively expressing enhanced green fluorescence protein, or media alone, were injected into the subarachnoid space of adult rats at 1 hour (acute stage), 7 days (subacute stage) and 28 days (chronic stage) after contusive spinal cord injury. Results showed that grafted neural progenitor cells migrated and aggregated around the blood vessels of the injured region, and infiltrated the spinal cord parenchyma along the tissue spaces in the acute stage transplantation group. However, this was not observed in subacute and chronic stage transplantation groups. 04- and glial fibrillary acidic protein-positive cells, representing oligodendrocytes and astrocytes respectively, were detected in the core of the grafted cluster attached to the cauda equina pia surface in the chronic stage transplantation group 8 weeks after transplantation. Both acute and subacute stage transplantation groups were negative for 04 and glial fibrillary acidic protein cells. Basso, Beattie and Bresnahan scale score comparisons indicated that rat hind limb locomotor activity showed better recovery after acute stage transplantation than after subacute and chronic transplantation. Our experimental findings suggest that the subarachnoid route could be useful for transplantation of neural progenitor cells at the acute stage of spinal cord injury. Although grafted cells survived only for a short time and did not differentiate into astrocytes or neurons, they were able to reach the parenchyma of the injured spinal cord and improve neurological function in rats. Transplantation efficacy was enhanced at the acute stage in comparison with subacute and chronic stages.
基金supported by the National Natural Science Foundation of China,No.81041092,81274116
文摘A preliminary study from our research group showed that picroside II inhibited neuronal apop- tosis in ischemic penumbra, reduced ischemic volume, and improved neurobehavioral function in rats with cerebral ischemia. The aim of the present study was to validate the neuroprotective effects of picroside II and optimize its therapeutic time window and dose in a rat model of cerebral ischemia. We found that picroside Ⅱ inhibited cell apoptosis and reduced the expression of neuron-specific enolase, a marker of neuronal damage, in rats after cerebral ischemic injury. The optimal treatment time after ischemic injury and dose were determined, respectively, as follows: (1) 2.0 hours and 10 mg/kg according to the results of toluidine blue staining; (2) 1.5 hours and 10 mg/kg according to early apoptotic ratio by flow cytometry; (3) 2.0 hours and 10 mg/kg according to immunohistochemical and western blot analysis; and (4) 1.5 hours and 10 mg/kg according to reverse transcription polymerase chain reaction. The present findings suggest that an intraperitoneal injection of 10 mg/kg picroside II 1.5-2.0 hours after cerebral ischemic injury in rats is the optimal dose and time for therapeutic benefit.