[Objectives]This study was conducted to determine the contents of benzoylmesaconine,benzoylaconitine and benzoylhypacoitine in the decoctions of Heishun pieces,Trichosanthis Fructus and their combination.[Methods]Heis...[Objectives]This study was conducted to determine the contents of benzoylmesaconine,benzoylaconitine and benzoylhypacoitine in the decoctions of Heishun pieces,Trichosanthis Fructus and their combination.[Methods]Heishun pieces,Trichosanthis Fructus and their combination were extracted for different time periods,and then grouped.HPLC was performed using an Agilent ZORBAX SB-C 18 chromatographic column(4.6 mm×250 mm,5μm)and acetonitrile-0.02 mol/L sodium dihydrogen phosphate as the mobile phase at a flow rate of 1 mL/min and a column temperature of 30℃,and the sample volume was 20μL.The detection wavelength was 230 nm.[Results]The total amounts of benzoylmesaconine,benzoylaconitine and benzoylhypacoitine in the single decoction group of Heishun pieces were all significantly different from those in the combined decoction group at corresponding time.[Conclusions]The total content of the benzoylaconitine type increased significantly after the combined decoction of Heishun pieces and Fructus Trichosanthis,which proves the scientificity of"eighteen incompatible medicaments,19 counteraction"in traditional Chinese medicine to some extent.展开更多
由于存在大的温度梯度,激光熔化沉积过程会沿沉积方向形成具有择优取向的粗大柱状晶,导致材料产生显著的各向异性。拟通过在钛合金中添加Cu以实现改变初生β晶粒形态、细化组织并弱化织构的目的。系统研究了不同含量的Cu添加对激光熔化...由于存在大的温度梯度,激光熔化沉积过程会沿沉积方向形成具有择优取向的粗大柱状晶,导致材料产生显著的各向异性。拟通过在钛合金中添加Cu以实现改变初生β晶粒形态、细化组织并弱化织构的目的。系统研究了不同含量的Cu添加对激光熔化沉积TC4钛合金组织及织构的影响,结果表明,Cu元素能够显著细化柱状初生β晶粒,并使晶粒尺寸分布更加均匀,Cu元素添加量为4%(质量分数,下同)时能够实现完全的柱状晶向等轴晶转变,平均晶粒尺寸由未添加时的1490μm降低到385μm。添加Cu试样的晶粒内部仍为网篮组织,主要由α-Ti、β-Ti和少量Ti2Cu相组成,其中Ti2Cu呈短棒状分布在α-Ti板条的边界处,其在组织中的占比随Cu添加量的增大而增加。当添加8%Cu时,α-Ti的平均宽度为0.44μm,与未添加Cu试样的1.18μm相比降低了约63%。Cu添加能够显著降低激光熔化沉积钛合金的织构强度,当添加4%Cu时,α-Ti极图均匀分布倍数(multiples of uniform distribution,MUD)的最大值相比TC4降低了约71%。展开更多
基金Supported by Project for Enhancing Young and Middle-aged Teacher's Scientific Research Basic Ability in Colleges and Universities of Guangxi in 2023 (2023KY0324).
文摘[Objectives]This study was conducted to determine the contents of benzoylmesaconine,benzoylaconitine and benzoylhypacoitine in the decoctions of Heishun pieces,Trichosanthis Fructus and their combination.[Methods]Heishun pieces,Trichosanthis Fructus and their combination were extracted for different time periods,and then grouped.HPLC was performed using an Agilent ZORBAX SB-C 18 chromatographic column(4.6 mm×250 mm,5μm)and acetonitrile-0.02 mol/L sodium dihydrogen phosphate as the mobile phase at a flow rate of 1 mL/min and a column temperature of 30℃,and the sample volume was 20μL.The detection wavelength was 230 nm.[Results]The total amounts of benzoylmesaconine,benzoylaconitine and benzoylhypacoitine in the single decoction group of Heishun pieces were all significantly different from those in the combined decoction group at corresponding time.[Conclusions]The total content of the benzoylaconitine type increased significantly after the combined decoction of Heishun pieces and Fructus Trichosanthis,which proves the scientificity of"eighteen incompatible medicaments,19 counteraction"in traditional Chinese medicine to some extent.
文摘由于存在大的温度梯度,激光熔化沉积过程会沿沉积方向形成具有择优取向的粗大柱状晶,导致材料产生显著的各向异性。拟通过在钛合金中添加Cu以实现改变初生β晶粒形态、细化组织并弱化织构的目的。系统研究了不同含量的Cu添加对激光熔化沉积TC4钛合金组织及织构的影响,结果表明,Cu元素能够显著细化柱状初生β晶粒,并使晶粒尺寸分布更加均匀,Cu元素添加量为4%(质量分数,下同)时能够实现完全的柱状晶向等轴晶转变,平均晶粒尺寸由未添加时的1490μm降低到385μm。添加Cu试样的晶粒内部仍为网篮组织,主要由α-Ti、β-Ti和少量Ti2Cu相组成,其中Ti2Cu呈短棒状分布在α-Ti板条的边界处,其在组织中的占比随Cu添加量的增大而增加。当添加8%Cu时,α-Ti的平均宽度为0.44μm,与未添加Cu试样的1.18μm相比降低了约63%。Cu添加能够显著降低激光熔化沉积钛合金的织构强度,当添加4%Cu时,α-Ti极图均匀分布倍数(multiples of uniform distribution,MUD)的最大值相比TC4降低了约71%。
