Inflammatory bowel disease(IBD),including both ulcerative colitis(UC) and Crohn's disease(CD),emerged and dramatically increased for about a century.Despite extensive research,its cause remains regarded as unknown...Inflammatory bowel disease(IBD),including both ulcerative colitis(UC) and Crohn's disease(CD),emerged and dramatically increased for about a century.Despite extensive research,its cause remains regarded as unknown.About a decade ago,a series of findings made me suspect that saccharin may be a key causative factor for IBD,through its inhibition on gut bacteria and the resultant impaired inactivation of digestive proteases and over digestion of the mucus layer and gut barrier(the Bacteria-Protease-Mucus-Barrier hypothesis).It explained many puzzles in IBD such as its emergence and temporal changes in last century.Recently I further found evidence suggesting sucralose may be also linked to IBD through a similar mechanism as saccharin and have contributed to the recent worldwide increase of IBD.This new hypothesis suggests that UC and CD are just two symptoms of the same morbidity,rather than two different diseases.They are both caused by a weakening in gut barrier and only differ in that UC is mainly due to increased infiltration of gut bacteria and the resultant recruitment of neutrophils and formation of crypt abscess,while CD is mainly due to increased infiltration of antigens and particles from gut lumen and the resultant recruitment of macrophages and formation of granulomas.It explained the delayed appearance but accelerated increase of CD over UC and many other phenomena.This paper aims to provide a detailed description of a unified hypothesis regardingthe etiology of IBD,including the cause and mechanism of IBD,as well as the relationship between UC and CD.展开更多
We offered the new theory of neutron (magnetic isotope) catalysis. For the first time it was shown that the number of neutrons in the atom, which have anomalous magnetic effect, have a great influence on the chemica...We offered the new theory of neutron (magnetic isotope) catalysis. For the first time it was shown that the number of neutrons in the atom, which have anomalous magnetic effect, have a great influence on the chemical properties. Our proposed theory of neutron (magnetic isotope) catalysis takes into account the influence of the magnetic field on the catalytic processes.展开更多
The study was conducted in water marshes for five major marshes during the months of January, April and September of each region (Hawizeh, Hammer and the central marsh) in southern Iraq. Bacteriological analysis tha...The study was conducted in water marshes for five major marshes during the months of January, April and September of each region (Hawizeh, Hammer and the central marsh) in southern Iraq. Bacteriological analysis that some of the default pathological bacteria, including TC (Total bacterial count), FCB (faecal coliform bacteria), MPN (coliform bacteria) and FS (faecal streptococcus) can evidence to indicate of pollution. The results showed that most of the water samples examined pathological contain bacteria which indicates that the water is unfit for human consumption and the waters as basal (more hydrogen than No. 7). There was a high salinity more than the permissible limits for human consumption and even to irrigate crops, and the same case for dissolve oxygen which exceeded are other limits as drinking water.展开更多
文摘Inflammatory bowel disease(IBD),including both ulcerative colitis(UC) and Crohn's disease(CD),emerged and dramatically increased for about a century.Despite extensive research,its cause remains regarded as unknown.About a decade ago,a series of findings made me suspect that saccharin may be a key causative factor for IBD,through its inhibition on gut bacteria and the resultant impaired inactivation of digestive proteases and over digestion of the mucus layer and gut barrier(the Bacteria-Protease-Mucus-Barrier hypothesis).It explained many puzzles in IBD such as its emergence and temporal changes in last century.Recently I further found evidence suggesting sucralose may be also linked to IBD through a similar mechanism as saccharin and have contributed to the recent worldwide increase of IBD.This new hypothesis suggests that UC and CD are just two symptoms of the same morbidity,rather than two different diseases.They are both caused by a weakening in gut barrier and only differ in that UC is mainly due to increased infiltration of gut bacteria and the resultant recruitment of neutrophils and formation of crypt abscess,while CD is mainly due to increased infiltration of antigens and particles from gut lumen and the resultant recruitment of macrophages and formation of granulomas.It explained the delayed appearance but accelerated increase of CD over UC and many other phenomena.This paper aims to provide a detailed description of a unified hypothesis regardingthe etiology of IBD,including the cause and mechanism of IBD,as well as the relationship between UC and CD.
文摘We offered the new theory of neutron (magnetic isotope) catalysis. For the first time it was shown that the number of neutrons in the atom, which have anomalous magnetic effect, have a great influence on the chemical properties. Our proposed theory of neutron (magnetic isotope) catalysis takes into account the influence of the magnetic field on the catalytic processes.
文摘The study was conducted in water marshes for five major marshes during the months of January, April and September of each region (Hawizeh, Hammer and the central marsh) in southern Iraq. Bacteriological analysis that some of the default pathological bacteria, including TC (Total bacterial count), FCB (faecal coliform bacteria), MPN (coliform bacteria) and FS (faecal streptococcus) can evidence to indicate of pollution. The results showed that most of the water samples examined pathological contain bacteria which indicates that the water is unfit for human consumption and the waters as basal (more hydrogen than No. 7). There was a high salinity more than the permissible limits for human consumption and even to irrigate crops, and the same case for dissolve oxygen which exceeded are other limits as drinking water.