目的:探讨慢性乙型肝炎(CHB)患者的病耻感状况及其影响因素。方法:2023年7月至2024年6月我院就诊的慢性乙肝患者120例,收集所有患者基本信息。采用SS患者病耻感水平,总结慢性乙肝患者病耻感现况;应用Logistic回归模型,分析慢性乙肝患者...目的:探讨慢性乙型肝炎(CHB)患者的病耻感状况及其影响因素。方法:2023年7月至2024年6月我院就诊的慢性乙肝患者120例,收集所有患者基本信息。采用SS患者病耻感水平,总结慢性乙肝患者病耻感现况;应用Logistic回归模型,分析慢性乙肝患者病耻感水平的影响因素。结果:此项研究收回有效问卷120份,他们在疾病羞耻度评分量表上的成绩跨度介于26至106分之间,平均得分71.16 ± 14.82分。经过对单一变量的研究发现,乙型肝炎患者的羞愧心理与其性别、年纪、教育水平、工作类型、婚姻状态、患病时间以及对疾病的处理方法存在显著性关联(P值小于0.05)。经由多变量线性回归考察得出,影响慢性乙型肝炎患者羞愧感受的关键变量包括年纪、教育水平、婚配情形及其应对策略,且统计学意义显著(P值小于0.05)。结论:乙型肝炎携带者普遍存在较强的疾病羞愧心理,此情绪状态与患者的年纪、教育水平、婚姻状况、得到的社交援助及应对策略紧密相关,针对此类情况,应实施有效的心理干预措施,降低乙型肝炎患者的羞病感,帮助其更顺利地融入社会。Objective: To explore the stigma of patients with chronic hepatitis B (CHB) and its influencing factors. Methods: There were 120 cases of chronic hepatitis B patients attending our hospital from July 2023 to June 2024, and the basic information of all patients was collected. SS patients’ level of stigma was used to summarize the current status of chronic hepatitis B patients’ stigma;Logistic regression model was applied to analyze the influencing factors of chronic hepatitis B patients’ level of stigma. Results: In this study, 120 valid questionnaires were returned and their scores on the Disease Shame Rating Scale spanned between 26 and 106 with a mean score of 71.16 ± 14.82. Upon examination of the single variables, it was found that there was a significant association (p-value less than 0.05) between the shame of patients with Hepatitis B and their gender, age, level of education, type of work, marital status, duration of illness, and their approach to the disease. A multivariate linear regression examination revealed that the key variables affecting the feelings of shame among chronic hepatitis B patients included age, level of education, marital status, and their coping strategies, and were statistically significant (p < 0.05). Conclusions: Hepatitis B carriers generally have strong disease shame, and this emotional state is closely related to the patient’s age, education level, marital status, social assistance received, and coping strategies. Effective psychological interventions should be implemented to address this situation, to reduce the disease shame of patients with hepatitis B, and to help them integrate into the community more smoothly.展开更多
记者:乙肝患者一定要接受抗病毒治疗吗?尚佳教授:先分享一个案例。26岁,男性,由他的母亲陪同来就诊。面色黄黄的,化验结果显示他的血浆甲胎蛋白(A F P)达到了6万多,B超检查显示有结节存在。我问他是什么病,他漫不经心地回答说他患有乙肝...记者:乙肝患者一定要接受抗病毒治疗吗?尚佳教授:先分享一个案例。26岁,男性,由他的母亲陪同来就诊。面色黄黄的,化验结果显示他的血浆甲胎蛋白(A F P)达到了6万多,B超检查显示有结节存在。我问他是什么病,他漫不经心地回答说他患有乙肝,这是他的第一句话。我问他最近是否喝酒,他告诉我.展开更多
目的应用核磁共振氢谱(nuclear magnetic resonance 1H,1H NMR)和主成分分析方法研究慢性乙肝患者血清的代谢组变化。方法临床正常人血清8例和慢性乙肝患者血清20例,采用BRUKER500MHz超导核磁共振波谱仪进行检测,并运用PCA分析方法,得...目的应用核磁共振氢谱(nuclear magnetic resonance 1H,1H NMR)和主成分分析方法研究慢性乙肝患者血清的代谢组变化。方法临床正常人血清8例和慢性乙肝患者血清20例,采用BRUKER500MHz超导核磁共振波谱仪进行检测,并运用PCA分析方法,得出慢性乙肝患者血清代谢组的特征,探讨相关生化过程的改变。结果分析结果显示慢性乙肝患者和正常人血清的代谢组具有明显差异。乙肝患者血清中的脂和葡萄糖是升高的,而乳酸、丙氨酸、缬氨酸、谷氨酰胺以及胆碱类物质则是降低的,且具有统计学意义(P<0.05)。结论通过上述代谢物的变化可以区分正常人和慢性乙肝患者。这种基于核磁共振氢谱和主成分分析的代谢组学方法可以为乙肝的诊断提供可靠的分子水平上的代谢依据。展开更多
文摘目的:探讨慢性乙型肝炎(CHB)患者的病耻感状况及其影响因素。方法:2023年7月至2024年6月我院就诊的慢性乙肝患者120例,收集所有患者基本信息。采用SS患者病耻感水平,总结慢性乙肝患者病耻感现况;应用Logistic回归模型,分析慢性乙肝患者病耻感水平的影响因素。结果:此项研究收回有效问卷120份,他们在疾病羞耻度评分量表上的成绩跨度介于26至106分之间,平均得分71.16 ± 14.82分。经过对单一变量的研究发现,乙型肝炎患者的羞愧心理与其性别、年纪、教育水平、工作类型、婚姻状态、患病时间以及对疾病的处理方法存在显著性关联(P值小于0.05)。经由多变量线性回归考察得出,影响慢性乙型肝炎患者羞愧感受的关键变量包括年纪、教育水平、婚配情形及其应对策略,且统计学意义显著(P值小于0.05)。结论:乙型肝炎携带者普遍存在较强的疾病羞愧心理,此情绪状态与患者的年纪、教育水平、婚姻状况、得到的社交援助及应对策略紧密相关,针对此类情况,应实施有效的心理干预措施,降低乙型肝炎患者的羞病感,帮助其更顺利地融入社会。Objective: To explore the stigma of patients with chronic hepatitis B (CHB) and its influencing factors. Methods: There were 120 cases of chronic hepatitis B patients attending our hospital from July 2023 to June 2024, and the basic information of all patients was collected. SS patients’ level of stigma was used to summarize the current status of chronic hepatitis B patients’ stigma;Logistic regression model was applied to analyze the influencing factors of chronic hepatitis B patients’ level of stigma. Results: In this study, 120 valid questionnaires were returned and their scores on the Disease Shame Rating Scale spanned between 26 and 106 with a mean score of 71.16 ± 14.82. Upon examination of the single variables, it was found that there was a significant association (p-value less than 0.05) between the shame of patients with Hepatitis B and their gender, age, level of education, type of work, marital status, duration of illness, and their approach to the disease. A multivariate linear regression examination revealed that the key variables affecting the feelings of shame among chronic hepatitis B patients included age, level of education, marital status, and their coping strategies, and were statistically significant (p < 0.05). Conclusions: Hepatitis B carriers generally have strong disease shame, and this emotional state is closely related to the patient’s age, education level, marital status, social assistance received, and coping strategies. Effective psychological interventions should be implemented to address this situation, to reduce the disease shame of patients with hepatitis B, and to help them integrate into the community more smoothly.
文摘目的应用核磁共振氢谱(nuclear magnetic resonance 1H,1H NMR)和主成分分析方法研究慢性乙肝患者血清的代谢组变化。方法临床正常人血清8例和慢性乙肝患者血清20例,采用BRUKER500MHz超导核磁共振波谱仪进行检测,并运用PCA分析方法,得出慢性乙肝患者血清代谢组的特征,探讨相关生化过程的改变。结果分析结果显示慢性乙肝患者和正常人血清的代谢组具有明显差异。乙肝患者血清中的脂和葡萄糖是升高的,而乳酸、丙氨酸、缬氨酸、谷氨酰胺以及胆碱类物质则是降低的,且具有统计学意义(P<0.05)。结论通过上述代谢物的变化可以区分正常人和慢性乙肝患者。这种基于核磁共振氢谱和主成分分析的代谢组学方法可以为乙肝的诊断提供可靠的分子水平上的代谢依据。
