目的探讨乙肝感染者血清前S1抗原检测在降低乙肝感染诊断假阴性率中的价值。方法选取2012年2月—2014年11月我院收治的乙型肝炎感染患者111例作为研究对象。取患者空腹肘静脉血,检测S1抗原、乙肝病毒标志物、乙肝病毒脱氧核糖核酸(H BV-...目的探讨乙肝感染者血清前S1抗原检测在降低乙肝感染诊断假阴性率中的价值。方法选取2012年2月—2014年11月我院收治的乙型肝炎感染患者111例作为研究对象。取患者空腹肘静脉血,检测S1抗原、乙肝病毒标志物、乙肝病毒脱氧核糖核酸(H BV-D N A)。结果血清前S1抗原(+)同H BV-D N A(+)比较,差异无统计学意义(P>0.05)。血清前S1抗原(+)同血清乙型肝炎e抗原(H Be A g)(+)比较,差异无统计学意义(P>0.05)。血清前S1抗原(+)同乙肝病毒标志物(+)比较,一致性较好。结论乙肝感染者血清前S1抗原检测在降低乙肝感染诊断假阴性率中有较好的诊断效果,可辅助乙肝感染的临床诊断。展开更多
Objective: In Slovenia the opportunistic cervical cancer (CC)screening programme has been performed within the regular gynaecological practice since 1960. The incidence rate 28.8/105 decreased to 16.1/105 in 1982, a...Objective: In Slovenia the opportunistic cervical cancer (CC)screening programme has been performed within the regular gynaecological practice since 1960. The incidence rate 28.8/105 decreased to 16.1/105 in 1982, and increased to 23/105 in 1996. To explain the increased CC incidence the patientsscreening histories, occurrence of symptoms, and details of preventive measures were studied on the basis of medical records and questionnaire. Errors of cytological screening were analysed by reviewing previous smears. Material: The answers obtained from 324 women, treated for CC in the period 1995-2000, were analysed in relation to age, stage and histology. The mean womens age was 46.76 ±13.07 (S.D.) years (range 23-85 years). After therapy, 271 patients were followedup by the end of January 2004, (mean followup time 80.3 ±20 S.D. months, range 29.7-110.3 months). Statistical analysis was performed using Chisquare test. Results: In 208 (80%) cases, CC was detected in stage 1, in 43 (17%) in stages 2A to 3B. Squamouscell carcinoma (192, 74.1%) was followed by adenocarcinoma (61, 23.5%) and (5, 1.9%) other malignancies. The screening interval ranged from 6 months to 4 years. Statistically significant differences existed between clinical and screening variables. CC was diagnosed in higher stages in women who were ignorant of the Pap test. Rescreened smears (n=126) showed 27.8%of false negative results. Conclusions: The reasons for high incidence of CC are poor performance of cytological screening, failures in gynecological examinations and diagnostic procedures, and the patientsnegligence of attending regular screening.展开更多
文摘目的探讨乙肝感染者血清前S1抗原检测在降低乙肝感染诊断假阴性率中的价值。方法选取2012年2月—2014年11月我院收治的乙型肝炎感染患者111例作为研究对象。取患者空腹肘静脉血,检测S1抗原、乙肝病毒标志物、乙肝病毒脱氧核糖核酸(H BV-D N A)。结果血清前S1抗原(+)同H BV-D N A(+)比较,差异无统计学意义(P>0.05)。血清前S1抗原(+)同血清乙型肝炎e抗原(H Be A g)(+)比较,差异无统计学意义(P>0.05)。血清前S1抗原(+)同乙肝病毒标志物(+)比较,一致性较好。结论乙肝感染者血清前S1抗原检测在降低乙肝感染诊断假阴性率中有较好的诊断效果,可辅助乙肝感染的临床诊断。
文摘Objective: In Slovenia the opportunistic cervical cancer (CC)screening programme has been performed within the regular gynaecological practice since 1960. The incidence rate 28.8/105 decreased to 16.1/105 in 1982, and increased to 23/105 in 1996. To explain the increased CC incidence the patientsscreening histories, occurrence of symptoms, and details of preventive measures were studied on the basis of medical records and questionnaire. Errors of cytological screening were analysed by reviewing previous smears. Material: The answers obtained from 324 women, treated for CC in the period 1995-2000, were analysed in relation to age, stage and histology. The mean womens age was 46.76 ±13.07 (S.D.) years (range 23-85 years). After therapy, 271 patients were followedup by the end of January 2004, (mean followup time 80.3 ±20 S.D. months, range 29.7-110.3 months). Statistical analysis was performed using Chisquare test. Results: In 208 (80%) cases, CC was detected in stage 1, in 43 (17%) in stages 2A to 3B. Squamouscell carcinoma (192, 74.1%) was followed by adenocarcinoma (61, 23.5%) and (5, 1.9%) other malignancies. The screening interval ranged from 6 months to 4 years. Statistically significant differences existed between clinical and screening variables. CC was diagnosed in higher stages in women who were ignorant of the Pap test. Rescreened smears (n=126) showed 27.8%of false negative results. Conclusions: The reasons for high incidence of CC are poor performance of cytological screening, failures in gynecological examinations and diagnostic procedures, and the patientsnegligence of attending regular screening.
