目的探讨养肺祛浊汤联合升清补气法针刺治疗慢性阻塞性肺疾病急性加重期(acute exacerbation of chronic obstructive pulmonary disease,AECOPD)合并呼吸衰竭的临床疗效。方法将93例AECOPD合并呼吸衰竭患者分为治疗组47例和对照组46例...目的探讨养肺祛浊汤联合升清补气法针刺治疗慢性阻塞性肺疾病急性加重期(acute exacerbation of chronic obstructive pulmonary disease,AECOPD)合并呼吸衰竭的临床疗效。方法将93例AECOPD合并呼吸衰竭患者分为治疗组47例和对照组46例。对照组剩42例(脱落5例)进行西医常规治疗。治疗组剩42例(脱落4例)在对照组基础上,进行养肺祛浊汤联合升清补气法针刺治疗。比较两组治疗14天的中医疗效。使用急性生理学和慢性健康状况量表(acute physiology and chronic health evaluationⅡ,APACHEⅡ)评估患者的病情严重程度。运用改良英国呼吸困难指数量表(modified British medical research cuncil,mMRC)评估患者呼吸困难程度。使用慢阻肺评估量表(COPD assessment test,CAT)评估患者的生活质量。检测两组患者血清中动脉血氧分压(partial pressure of oxygen,PaO 2)、氧合指数(oxygenation index,OI)、浅快呼吸指数(rapid shallow breathing index,RSBI)、高迁移率族蛋白B1(high mobility group box b1,HMGB1)、超敏C反应蛋白(hypersensitivity creactive protein,hs-CRP)、中性粒细胞/淋巴细胞比值(neutrophit-to-lymphocyte ratio,NLR)的水平。比较两组肺功能的变化。结果治疗14天,治疗组的中医疗效比对照组高(95.24%vs 78.57%,P<0.05)。治疗后,两组的APACHEⅡ、mMRC、CAT均比治疗前低(P<0.05);治疗组治疗后的APACHEⅡ、mMRC、CAT均比对照组低(P<0.05)。治疗后,两组的PaO 2、OI比治疗前高,RSBI比治疗前低(P<0.05);治疗组治疗后的PaO 2、OI比对照组高,RSBI比对照组低(P<0.05)。两组治疗后的HMGB1、hs-CRP、NLR比治疗前低(P<0.05);治疗组治疗后的HMGB1、hs-CRP、NLR比对照组低(P<0.05)。治疗后,两组的第一秒呼出气体量/用力肺活量(forced expiratory volume in one second/forced vital capacity,FEV1/FVC)和最大呼气流量(peak expiratory flow,PEF)比治疗前高(P<0.05);治疗组治疗后的FEV1/FVC、PEF比对照组大(P<0.05)。结论养肺祛浊汤联合升清补气法针刺可提高AECOPD合并呼吸衰竭的中医疗效,减轻病情严重程度和呼吸困难程度,改善患者生活质量和血气指标,显著减轻炎症反应,提高肺功能。展开更多
直肠癌是消化道常见的恶性肿瘤,发病率在逐年升高,目前以外科手术为主要治疗方式,术后会产生低位前切除综合征(LARS),严重影响患者的身心健康及生活质量,是一个不可忽视的临床难题。姜毅教授在长期的临床实践中观察到LARS患者大多以脾...直肠癌是消化道常见的恶性肿瘤,发病率在逐年升高,目前以外科手术为主要治疗方式,术后会产生低位前切除综合征(LARS),严重影响患者的身心健康及生活质量,是一个不可忽视的临床难题。姜毅教授在长期的临床实践中观察到LARS患者大多以脾虚下陷为主,临床上常基于“脾主升清”理论,治以益气健脾、升阳举陷,能够有效缓解患者的临床症状,提高患者的生活质量,临床疗效显著。本文总结了姜毅教授治疗LARS的临床经验,为中医药治疗本病提供治疗思路。Rectal cancer is a common malignant tumor of the digestive tract, and its incidence is increasing year by year. At present, surgery is the main treatment mode, which will produce low anterior resection syndrome (LARS) after surgery, which seriously affects the physical and mental health and quality of life of patients. It is a clinical problem that cannot be ignored. In long-term clinical practice, Professor Jiang Yi observed that most LARS patients mainly suffer from spleen deficiency. Clinically, based on the theory of “spleen main rise clear”, they often treat qi and spleen and lift Yang lift subsidence, which can effectively relieve the clinical symptoms of patients, improve the quality of life of patients, and has remarkable clinical effects. This paper summarizes the clinical experience of Professor Jiang Yi in the treatment of LARS, and provides therapeutic ideas for the treatment of this disease.展开更多
文摘目的探讨养肺祛浊汤联合升清补气法针刺治疗慢性阻塞性肺疾病急性加重期(acute exacerbation of chronic obstructive pulmonary disease,AECOPD)合并呼吸衰竭的临床疗效。方法将93例AECOPD合并呼吸衰竭患者分为治疗组47例和对照组46例。对照组剩42例(脱落5例)进行西医常规治疗。治疗组剩42例(脱落4例)在对照组基础上,进行养肺祛浊汤联合升清补气法针刺治疗。比较两组治疗14天的中医疗效。使用急性生理学和慢性健康状况量表(acute physiology and chronic health evaluationⅡ,APACHEⅡ)评估患者的病情严重程度。运用改良英国呼吸困难指数量表(modified British medical research cuncil,mMRC)评估患者呼吸困难程度。使用慢阻肺评估量表(COPD assessment test,CAT)评估患者的生活质量。检测两组患者血清中动脉血氧分压(partial pressure of oxygen,PaO 2)、氧合指数(oxygenation index,OI)、浅快呼吸指数(rapid shallow breathing index,RSBI)、高迁移率族蛋白B1(high mobility group box b1,HMGB1)、超敏C反应蛋白(hypersensitivity creactive protein,hs-CRP)、中性粒细胞/淋巴细胞比值(neutrophit-to-lymphocyte ratio,NLR)的水平。比较两组肺功能的变化。结果治疗14天,治疗组的中医疗效比对照组高(95.24%vs 78.57%,P<0.05)。治疗后,两组的APACHEⅡ、mMRC、CAT均比治疗前低(P<0.05);治疗组治疗后的APACHEⅡ、mMRC、CAT均比对照组低(P<0.05)。治疗后,两组的PaO 2、OI比治疗前高,RSBI比治疗前低(P<0.05);治疗组治疗后的PaO 2、OI比对照组高,RSBI比对照组低(P<0.05)。两组治疗后的HMGB1、hs-CRP、NLR比治疗前低(P<0.05);治疗组治疗后的HMGB1、hs-CRP、NLR比对照组低(P<0.05)。治疗后,两组的第一秒呼出气体量/用力肺活量(forced expiratory volume in one second/forced vital capacity,FEV1/FVC)和最大呼气流量(peak expiratory flow,PEF)比治疗前高(P<0.05);治疗组治疗后的FEV1/FVC、PEF比对照组大(P<0.05)。结论养肺祛浊汤联合升清补气法针刺可提高AECOPD合并呼吸衰竭的中医疗效,减轻病情严重程度和呼吸困难程度,改善患者生活质量和血气指标,显著减轻炎症反应,提高肺功能。
文摘直肠癌是消化道常见的恶性肿瘤,发病率在逐年升高,目前以外科手术为主要治疗方式,术后会产生低位前切除综合征(LARS),严重影响患者的身心健康及生活质量,是一个不可忽视的临床难题。姜毅教授在长期的临床实践中观察到LARS患者大多以脾虚下陷为主,临床上常基于“脾主升清”理论,治以益气健脾、升阳举陷,能够有效缓解患者的临床症状,提高患者的生活质量,临床疗效显著。本文总结了姜毅教授治疗LARS的临床经验,为中医药治疗本病提供治疗思路。Rectal cancer is a common malignant tumor of the digestive tract, and its incidence is increasing year by year. At present, surgery is the main treatment mode, which will produce low anterior resection syndrome (LARS) after surgery, which seriously affects the physical and mental health and quality of life of patients. It is a clinical problem that cannot be ignored. In long-term clinical practice, Professor Jiang Yi observed that most LARS patients mainly suffer from spleen deficiency. Clinically, based on the theory of “spleen main rise clear”, they often treat qi and spleen and lift Yang lift subsidence, which can effectively relieve the clinical symptoms of patients, improve the quality of life of patients, and has remarkable clinical effects. This paper summarizes the clinical experience of Professor Jiang Yi in the treatment of LARS, and provides therapeutic ideas for the treatment of this disease.
