A numerical analysis of the log-law behavior for the turbulent boundary layer of a wall-bounded flow is performed over a flat plate immersed in three nanofluids(Zn O-water,SiO_(2)-water,TiO_(2)-water).Numerical simula...A numerical analysis of the log-law behavior for the turbulent boundary layer of a wall-bounded flow is performed over a flat plate immersed in three nanofluids(Zn O-water,SiO_(2)-water,TiO_(2)-water).Numerical simulations using CFD code are employed to investigate the boundary layer and the hydrodynamic flow.To validate the current numerical model,measurement points from published works were used,and the compared results were in good compliance.Simulations were carried out for the velocity series of 0.04,0.4 and 4 m/s and nanoparticle concentrations0.1% and 5%.The influence of nanoparticles’ concentration on velocity,temperature profiles,wall shear stress,and turbulent intensity was investigated.The obtained results showed that the viscous sub-layer,the buffer layer,and the loglaw layer along the potential-flow layer could be analyzed based on their curving quality in the regions which have just a single wall distance.It was seen that the viscous sub-layer is the biggest area in comparison with other areas.Alternatively,the section where the temperature changes considerably correspond to the thermal boundary layer’s thickness goes a downward trend when the velocity decreases.The thermal boundary layer gets deep away from the leading edge.However,a rise in the volume fraction of nanoparticles indicated a minor impact on the shear stress developed in the wall.In all cases,the thickness of the boundary layer undergoes a downward trend as the velocity increases,whereas increasing the nanoparticle concentrations would enhance the thickness.More precisely,the log layer is closed with log law,and it is minimal between Y^(+)=50 and Y^(+)=95.The temperature for nanoparticle concentration φ=5%is higher than that for φ=0.1%,in boundary layers,for all studied nanofluids.However,it is established that the behavior is inverted from the value of Y^(+)=1 and the temperature for φ =0.1% is more important than the case of φ =5%.For turbulence intensity peak,this peak exists at Y^(+)=100 for v=4 m/s,Y^(+)=10 for v=0.4 m/s and Y^(+)=8 for v=0.04 m/s.展开更多
Non-Newtonian fluid model for blood flow through a tapered artery with a stenosis and variable viscosity by modeling blood as Jeffrey fluid has been studied in this paper. The Jeffrey fluid has two parameters, the rel...Non-Newtonian fluid model for blood flow through a tapered artery with a stenosis and variable viscosity by modeling blood as Jeffrey fluid has been studied in this paper. The Jeffrey fluid has two parameters, the relaxation time A1 and retardation time A2. The governing equations are simplified using the case of mild stenosis. Perturbation method is used to solve the resulting equations. The effects of non-Newtonian nature of blood on velocity profile, temperature profile, wall shear stress, shearing stress at the stenotsis throat and impedance of the artery are discussed. The results for Newtonian fluid are obtained as special case from this model.展开更多
This paper reports experimental and computational fluid dynamics(CFD) studies on the performance of microfiltration enhanced by a helical screw insert.The experimental results show that the use of turbulence pro-moter...This paper reports experimental and computational fluid dynamics(CFD) studies on the performance of microfiltration enhanced by a helical screw insert.The experimental results show that the use of turbulence pro-moter can improve the permeate flux of membrane in the crossflow microfiltration of calcium carbonate suspension,and flux improvement efficiency is strongly influenced by operation conditions.The energy consumption analysis indicates that the enhanced membrane system is more energy saving at higher feed concentrations.To explore the intrinsic mechanism of flux enhancement by a helical screw insert,three-dimensional CFD simulation of fluid flow was implemented.It reveals that hydrodynamic characteristics of fluid flow inside the channel are entirely changed by the turbulence promoter.The rotational flow pattern increases the scouring effect on the tube wall,reducing the particle deposition on the membrane surface.The absence of stagnant regions and high wall shear stress are respon-sible for the enhanced filtration performance.No secondary flow is generated in the channel,owing to the streamline shape of helical screw insert,so that the enhanced performance is achieved at relatively low energy consumption.展开更多
The stent was a major breakthrough in the treatment of atherosclerotic vascular disease. The permanent vascular implant of a stent, however, changes the intra-stent blood flow hemodynamics. There is a growing consensu...The stent was a major breakthrough in the treatment of atherosclerotic vascular disease. The permanent vascular implant of a stent, however, changes the intra-stent blood flow hemodynamics. There is a growing consensus that the stent implant may change the artery wall shear stress distribution and hence lead to the restenosis process. Computational fluid dynamics （CFD） has been widely used to analyze hemodynamics in stented arteries. In this paper, two CFD models （the axisymmetric model and the 3-D stent model） were developed to investigate the effects of strut geometry and blood rheology on the intra-stent hemodynamics. The velocity profile, flow recirculation, and wall shear stress distribution of various stent strut geometries were studied. Results show strong correlations between the intra-stent hemodynamics and strut geometry. The intra-stent blood flow is very sensitive to the strut height and fillet size. A round strut with a large fillet size shows 36% and 34% reductions in key parameters evaluating the restenosis risk for the axisymmetric model and the 3-D stent model, respectively. This suggests that electrochemical polishing, a surface-improving process during stent manufacturing, strongly influences the hemodynamic behavior in stented arteries and should be controlled precisely in order to achieve the best clinical outcome. Rheological effects on the wall shear stress are minor in both axisymmetric and 3-D stent models for the vessel diameter of 4 mm, with Newtonian flow simulation tending to give more conservative estimates ofrestenosis risk. Therefore, it is reasonable to simulate the blood flow as a Newtonian flow in stented arteries using the simpler axisymmetric model. These findings will provide great insights for stent design optimization for potential restenosis improvement.展开更多
The wall shear stress （WSS） that a moving fluid exerts on a surface affects many processes including those relating to vascular function. WSS plays an important role in normal physiology （e.g. angiogenesis） and af...The wall shear stress （WSS） that a moving fluid exerts on a surface affects many processes including those relating to vascular function. WSS plays an important role in normal physiology （e.g. angiogenesis） and affects the microvasculature＇s primary function of molecular transport. Points of fluctuating WSS show abnormalities in a number of diseases; however, there is no established technique for measuring WSS directly in physiological systems. All current methods rely on estimates obtained from measured velocity gradients in bulk flow data. In this work, we report a nanosensor that can directly measure WSS in microfluidic chambers with sub-micron spatial resolution by using a specific type of virus, the bacteriophage M13, which has been fluorescently labeled and anchored to a surface. It is demonstrated that the nanosensor can be calibrated and adapted for biological tissue, revealing WSS in micro-domains of cells that cannot be calculated accurately from bulk flow measurements. This method lends itself to a platform applicable to many applications in biology and microfluidics.展开更多
In this paper, a mathematical model for steady blood flow through blood vessels with uniform cross-section in stenoses arteries has been proposed. Blood is assumed to be non- Newtonian, incompressible and homogeneous ...In this paper, a mathematical model for steady blood flow through blood vessels with uniform cross-section in stenoses arteries has been proposed. Blood is assumed to be non- Newtonian, incompressible and homogeneous fluid. Blood in human artery is represented as Bingham plastic fluid. Expressions for flow rate, wall shear stress, and resistance to flow against stenoses size have been obtained. Obtained results indicate that stenoses size decreases the flow rate and increases the wall shear stress as well as resistance to flow.展开更多
In this paper, the outline of the Mach 4 supersonic wind tunnel for the investigation of the supersonic internal flows in ducts was firstly described. Secondly, the location, structure and characteristics of the Mach ...In this paper, the outline of the Mach 4 supersonic wind tunnel for the investigation of the supersonic internal flows in ducts was firstly described. Secondly, the location, structure and characteristics of the Mach 2 and Mach 4 pseudo-shock waves in a square duct were investigated by color schlieren photographs and duct wall pressure fluctuation measurements. Finally, the wall shear stress distributions on the side, top and bottom walls of the square duct with the Mach 4 pseudo-shock wave were investigated qualitatively by the shear stress-sensitive liquid crystal visualization method. The side wall boundary layer separation region under the first shock is narrow near the top wall, while the side wall boundary layer separation region under the first shock is very wide near the bottom wall.展开更多
The hemodynamics of intracranial aneurysm(IA)comprises complex transient flow patterns that affect its growth and rupture.Owing to the combined effects of geometrical factors and pulsatile flow conditions,the transien...The hemodynamics of intracranial aneurysm(IA)comprises complex transient flow patterns that affect its growth and rupture.Owing to the combined effects of geometrical factors and pulsatile flow conditions,the transient flow patterns in the IA are still unclear.The purpose of this work is to reveal the effect of the aspect ratio(AR,sac height/neck width)on the evolution of the internal flow patterns and the hemodynamics of the IA.We proposed an easy method to fabricate three simplified elastic IA models and measured the transient flow characteristics by using particle image velocimetry(PIV).Transient vortex structures in the IA modes during a cardiac cycle were systemically measured and many new flow phenomena were found,including the vortex morphology(size,structure,and core location),a high-speed jet,wall compliance effects,and three flow modes during retrograde flow phase.The results show that the AR of the IA affects the transient flow patterns as well as the wall shear stress(WSS)in complex ways.The results could deepen our understanding of the transient flow behaviors in IA and guide related clinical studies.展开更多
In this paper, steady incompressible micropolar fluid flow through a non-uniform channel with multiple stenoses is considered. Assuming the stenoses to be mild and using the slip boundary condition, the equations gove...In this paper, steady incompressible micropolar fluid flow through a non-uniform channel with multiple stenoses is considered. Assuming the stenoses to be mild and using the slip boundary condition, the equations governing the flow of the proposed model are solved, and closed-form expressions for the flow characteristics （resistance to flow and wall shear stress） are derived. The effects of different parameters on these flow characteristics are analyzed. It is observed that both the resistance to the flow and the wall shear stress increase with the heights of the stenoses and the slip parameter; but decrease with the Darcy number, b^rthermore, the effects of the wall exponent parameter, the cross-viscosity coefficient and the micropolar parameter on the flow characteristics are discussed.展开更多
基金support he received through General Research Project under the grant number (R.G.P.2/138/42)。
文摘A numerical analysis of the log-law behavior for the turbulent boundary layer of a wall-bounded flow is performed over a flat plate immersed in three nanofluids(Zn O-water,SiO_(2)-water,TiO_(2)-water).Numerical simulations using CFD code are employed to investigate the boundary layer and the hydrodynamic flow.To validate the current numerical model,measurement points from published works were used,and the compared results were in good compliance.Simulations were carried out for the velocity series of 0.04,0.4 and 4 m/s and nanoparticle concentrations0.1% and 5%.The influence of nanoparticles’ concentration on velocity,temperature profiles,wall shear stress,and turbulent intensity was investigated.The obtained results showed that the viscous sub-layer,the buffer layer,and the loglaw layer along the potential-flow layer could be analyzed based on their curving quality in the regions which have just a single wall distance.It was seen that the viscous sub-layer is the biggest area in comparison with other areas.Alternatively,the section where the temperature changes considerably correspond to the thermal boundary layer’s thickness goes a downward trend when the velocity decreases.The thermal boundary layer gets deep away from the leading edge.However,a rise in the volume fraction of nanoparticles indicated a minor impact on the shear stress developed in the wall.In all cases,the thickness of the boundary layer undergoes a downward trend as the velocity increases,whereas increasing the nanoparticle concentrations would enhance the thickness.More precisely,the log layer is closed with log law,and it is minimal between Y^(+)=50 and Y^(+)=95.The temperature for nanoparticle concentration φ=5%is higher than that for φ=0.1%,in boundary layers,for all studied nanofluids.However,it is established that the behavior is inverted from the value of Y^(+)=1 and the temperature for φ =0.1% is more important than the case of φ =5%.For turbulence intensity peak,this peak exists at Y^(+)=100 for v=4 m/s,Y^(+)=10 for v=0.4 m/s and Y^(+)=8 for v=0.04 m/s.
文摘Non-Newtonian fluid model for blood flow through a tapered artery with a stenosis and variable viscosity by modeling blood as Jeffrey fluid has been studied in this paper. The Jeffrey fluid has two parameters, the relaxation time A1 and retardation time A2. The governing equations are simplified using the case of mild stenosis. Perturbation method is used to solve the resulting equations. The effects of non-Newtonian nature of blood on velocity profile, temperature profile, wall shear stress, shearing stress at the stenotsis throat and impedance of the artery are discussed. The results for Newtonian fluid are obtained as special case from this model.
基金Supported by the National Science Fund for Distinguished Young Scholars of China (21125628)the National High Technology Research and Development Program of China (2012AA03A611)the Fundamental Research Fund for the Central Universities (DUT11ZD112)
文摘This paper reports experimental and computational fluid dynamics(CFD) studies on the performance of microfiltration enhanced by a helical screw insert.The experimental results show that the use of turbulence pro-moter can improve the permeate flux of membrane in the crossflow microfiltration of calcium carbonate suspension,and flux improvement efficiency is strongly influenced by operation conditions.The energy consumption analysis indicates that the enhanced membrane system is more energy saving at higher feed concentrations.To explore the intrinsic mechanism of flux enhancement by a helical screw insert,three-dimensional CFD simulation of fluid flow was implemented.It reveals that hydrodynamic characteristics of fluid flow inside the channel are entirely changed by the turbulence promoter.The rotational flow pattern increases the scouring effect on the tube wall,reducing the particle deposition on the membrane surface.The absence of stagnant regions and high wall shear stress are respon-sible for the enhanced filtration performance.No secondary flow is generated in the channel,owing to the streamline shape of helical screw insert,so that the enhanced performance is achieved at relatively low energy consumption.
文摘The stent was a major breakthrough in the treatment of atherosclerotic vascular disease. The permanent vascular implant of a stent, however, changes the intra-stent blood flow hemodynamics. There is a growing consensus that the stent implant may change the artery wall shear stress distribution and hence lead to the restenosis process. Computational fluid dynamics （CFD） has been widely used to analyze hemodynamics in stented arteries. In this paper, two CFD models （the axisymmetric model and the 3-D stent model） were developed to investigate the effects of strut geometry and blood rheology on the intra-stent hemodynamics. The velocity profile, flow recirculation, and wall shear stress distribution of various stent strut geometries were studied. Results show strong correlations between the intra-stent hemodynamics and strut geometry. The intra-stent blood flow is very sensitive to the strut height and fillet size. A round strut with a large fillet size shows 36% and 34% reductions in key parameters evaluating the restenosis risk for the axisymmetric model and the 3-D stent model, respectively. This suggests that electrochemical polishing, a surface-improving process during stent manufacturing, strongly influences the hemodynamic behavior in stented arteries and should be controlled precisely in order to achieve the best clinical outcome. Rheological effects on the wall shear stress are minor in both axisymmetric and 3-D stent models for the vessel diameter of 4 mm, with Newtonian flow simulation tending to give more conservative estimates ofrestenosis risk. Therefore, it is reasonable to simulate the blood flow as a Newtonian flow in stented arteries using the simpler axisymmetric model. These findings will provide great insights for stent design optimization for potential restenosis improvement.
文摘The wall shear stress （WSS） that a moving fluid exerts on a surface affects many processes including those relating to vascular function. WSS plays an important role in normal physiology （e.g. angiogenesis） and affects the microvasculature＇s primary function of molecular transport. Points of fluctuating WSS show abnormalities in a number of diseases; however, there is no established technique for measuring WSS directly in physiological systems. All current methods rely on estimates obtained from measured velocity gradients in bulk flow data. In this work, we report a nanosensor that can directly measure WSS in microfluidic chambers with sub-micron spatial resolution by using a specific type of virus, the bacteriophage M13, which has been fluorescently labeled and anchored to a surface. It is demonstrated that the nanosensor can be calibrated and adapted for biological tissue, revealing WSS in micro-domains of cells that cannot be calculated accurately from bulk flow measurements. This method lends itself to a platform applicable to many applications in biology and microfluidics.
文摘In this paper, a mathematical model for steady blood flow through blood vessels with uniform cross-section in stenoses arteries has been proposed. Blood is assumed to be non- Newtonian, incompressible and homogeneous fluid. Blood in human artery is represented as Bingham plastic fluid. Expressions for flow rate, wall shear stress, and resistance to flow against stenoses size have been obtained. Obtained results indicate that stenoses size decreases the flow rate and increases the wall shear stress as well as resistance to flow.
文摘In this paper, the outline of the Mach 4 supersonic wind tunnel for the investigation of the supersonic internal flows in ducts was firstly described. Secondly, the location, structure and characteristics of the Mach 2 and Mach 4 pseudo-shock waves in a square duct were investigated by color schlieren photographs and duct wall pressure fluctuation measurements. Finally, the wall shear stress distributions on the side, top and bottom walls of the square duct with the Mach 4 pseudo-shock wave were investigated qualitatively by the shear stress-sensitive liquid crystal visualization method. The side wall boundary layer separation region under the first shock is narrow near the top wall, while the side wall boundary layer separation region under the first shock is very wide near the bottom wall.
基金supported by the National Natural Science Foundation of China(Grant Nos:12172017 and 11872083)Project of Beijing Municipal Education Commission(Grant Nos.KZ202210005006 and KZ202110005007).
文摘The hemodynamics of intracranial aneurysm(IA)comprises complex transient flow patterns that affect its growth and rupture.Owing to the combined effects of geometrical factors and pulsatile flow conditions,the transient flow patterns in the IA are still unclear.The purpose of this work is to reveal the effect of the aspect ratio(AR,sac height/neck width)on the evolution of the internal flow patterns and the hemodynamics of the IA.We proposed an easy method to fabricate three simplified elastic IA models and measured the transient flow characteristics by using particle image velocimetry(PIV).Transient vortex structures in the IA modes during a cardiac cycle were systemically measured and many new flow phenomena were found,including the vortex morphology(size,structure,and core location),a high-speed jet,wall compliance effects,and three flow modes during retrograde flow phase.The results show that the AR of the IA affects the transient flow patterns as well as the wall shear stress(WSS)in complex ways.The results could deepen our understanding of the transient flow behaviors in IA and guide related clinical studies.
文摘In this paper, steady incompressible micropolar fluid flow through a non-uniform channel with multiple stenoses is considered. Assuming the stenoses to be mild and using the slip boundary condition, the equations governing the flow of the proposed model are solved, and closed-form expressions for the flow characteristics （resistance to flow and wall shear stress） are derived. The effects of different parameters on these flow characteristics are analyzed. It is observed that both the resistance to the flow and the wall shear stress increase with the heights of the stenoses and the slip parameter; but decrease with the Darcy number, b^rthermore, the effects of the wall exponent parameter, the cross-viscosity coefficient and the micropolar parameter on the flow characteristics are discussed.
