2011年11月14-17日，由浙江大学化学系和浙江省化学学会主办的第5届多组分反应及相关化学国际研讨会（The 5th International Conference on Multi-Component Reactions and Related Chemistry，MCR2011）在杭州顺利召开。浙江大学化学...2011年11月14-17日，由浙江大学化学系和浙江省化学学会主办的第5届多组分反应及相关化学国际研讨会（The 5th International Conference on Multi-Component Reactions and Related Chemistry，MCR2011）在杭州顺利召开。浙江大学化学系系主任、浙江省化学会理事长王彦广教授和瑞士洛桑理工大学祝介平教授共同担任了会议主席，浙江大学吕萍教授担任会议秘书，组委会成员包括浙江大学化学系的戴伟民教授，林旭峰教授，马成教授，任红军特聘研究员和史炳锋特聘研究员。展开更多
A series of coumarin-chalcone hybrid compounds and coumarins linked to pyrazoline was synthesized in good yield and short time using a simple and efficient method. This method involved the one-pot reaction of salicyla...A series of coumarin-chalcone hybrid compounds and coumarins linked to pyrazoline was synthesized in good yield and short time using a simple and efficient method. This method involved the one-pot reaction of salicylaldehyde, an α-ketoester and an aromatic aldehyde(in the case of the coumarin-chalcone derivatives) in addition to hydrazine hydrate(in the case of the pyrazolyl coumarins) in the presence of a catalytic amount of bismuth triflate [Bi(OTf)3, 5 mol%]. The synthesized compounds showed scavenging activity towards the free radical 2,2-diphenyl-1-picrylhydrazyl. All compounds were characterized using IR, 1H NMR and 13 C NMR spectroscopy.展开更多
文摘2011年11月14-17日，由浙江大学化学系和浙江省化学学会主办的第5届多组分反应及相关化学国际研讨会（The 5th International Conference on Multi-Component Reactions and Related Chemistry，MCR2011）在杭州顺利召开。浙江大学化学系系主任、浙江省化学会理事长王彦广教授和瑞士洛桑理工大学祝介平教授共同担任了会议主席，浙江大学吕萍教授担任会议秘书，组委会成员包括浙江大学化学系的戴伟民教授，林旭峰教授，马成教授，任红军特聘研究员和史炳锋特聘研究员。
基金Sohag University in Egypt for supporting and facilitating this study
文摘A series of coumarin-chalcone hybrid compounds and coumarins linked to pyrazoline was synthesized in good yield and short time using a simple and efficient method. This method involved the one-pot reaction of salicylaldehyde, an α-ketoester and an aromatic aldehyde(in the case of the coumarin-chalcone derivatives) in addition to hydrazine hydrate(in the case of the pyrazolyl coumarins) in the presence of a catalytic amount of bismuth triflate [Bi(OTf)3, 5 mol%]. The synthesized compounds showed scavenging activity towards the free radical 2,2-diphenyl-1-picrylhydrazyl. All compounds were characterized using IR, 1H NMR and 13 C NMR spectroscopy.
