曲马多用于手术后镇痛的临床评价(附40例报告)

观察曲马多用于术后镇痛的效果 ,结果证明曲马多是一种新型非麻醉性中枢镇痛药 ,可广泛应用于术后镇痛 ,对呼吸循环无抑制作用 ,无成瘾性。

不同剂量曲马多用于小儿全麻术后镇痛的临床研究

曲多马作为非麻醉性镇痛药具有不抑制呼吸的特点，是小儿术后镇痛的理想用药，本文旨在探讨曲马多用于小儿全麻术后镇痛的最佳剂量。

曲马多加米索前列醇联合利多卡因在人工流产术中的应用

目的 探讨曲马多加米索前列醇联合利多卡因在人工流产术中终止早孕的效果.方法 将320例人工流产者分为A、B两组,每组160例.A组分别于术前2h宫颈管内放置米索前列醇片200 μg,1h后给予曲马多针0.1g肌注,术前给予宫颈3、9点处注入2％利多卡因2 mL,3～5 min后手术,对于紧张、恐惧者术前给予安定10mg静推;B组术前给予宫颈3、9点处注入2％利多卡因2 mL,3～5 min后手术.结果 A组镇痛效果优于B组.结论 曲马多加米索前列醇联合利多卡因在人工流产术中应用值得推广.

Comparative study of caudal bupivacaine versus bupivacaine with tramadol for postoperative analgesia in paediatric cancer patients

Objective:Caudal epidural analgesia has become very common analgesic technique in paediatric surgery.Adding tramadol to bupivacaine for caudal injection prolongs duration of analgesia with minimal side effects.The aim of the study was to investigate the different effects of caudal bupivacaine versus bupivacaine with thamadol for postoperative analgesia in paediatric cancer patients.Methods:A prospective randomized controlled trial was conducted over 40 paediatric cancer patients who were recruited from Children Cancer Hospital of Egypt(57357 Hospital).Patients were randomized into 2 groups:bupivacaine group(group B,20 patients) to receive single shot caudal block of 1 mL/kg 0.1875% bupivacaine;tramadol group(group T,20 patients) prepared as group B with the addition of 1 mg/kg caudal tramadol.Results:The mean duration of analgesia was significantly longer among group T than group B [(24 ± 13.7) hours versus(7 ± 3.7) hours respectively with P = 0.001].Group T showed a significantly lower mean FLACC score than group B(2.2 ± 0.9 versus 3.6 ± 0.6 with P = 0.002).The difference in FLACC score was comparable on arrival,and after 2 and 4 hours.At 8 and 12 hours the group B recorded significantly higher scores(P = 0.002 and 0.0001 respectively).There were no significant differences between the groups as regards sedation score [the median in both groups was 1(0-1) with P value = o.8].No one developed facial flush or pruritis.Conclusion:Caudal injection of low dose tramadol 1 mg/kg with bupivacaine 0.1875% is proved to be effective,long standing technique for postoperative analgesia in major paediatric cancer surgery and almost devoid of side effect.

曲马多治疗术中寒战的临床应用效果观察

在阑尾炎手术中,探讨当患者出现寒战时进行曲马多治疗的效果。方法:在2019年6月至2020年6月间,选择进行阑尾炎手术的患者,共90名,手术前均使用硬膜外麻醉。随机将上述患者平均分为试验组和对照组。试验组患者给予药物为曲马多,对照组患者给予药物咪达唑仑。通过Ramsay评分对患者的寒战程度进行判定,治疗期间认真观察患者产生不良反应的情况。结果:阑尾炎手术后,对照组患者的镇静评分高于试验组患者(P<0.05)。对患者的入睡情况进行分析,对照组患者有轻度的呼吸抑制,而试验组患者睡眠质量较高,无打鼾,呼吸通畅。对照组患者的不良反应发生率也高于试验组患者(P<0.05)。结论:当患者手术前进行硬膜外麻醉时,通过曲马多进行预防治疗可在一定程度上改善患者的寒战情况,提高患者的睡眠质量,降低患者产生不良反应的概率,建议在外科中进行推广。