To get the satisfying performance of a PID controller, this paper presents a novel Pareto-based multi-objective genetic algorithm (MOGA), which can be used to find the appropriate setting of the PID controller by anal...To get the satisfying performance of a PID controller, this paper presents a novel Pareto-based multi-objective genetic algorithm (MOGA), which can be used to find the appropriate setting of the PID controller by analyzing the pareto optimal surfaces. Rated settings of the controller by two criteria, the error between output and reference signals and control moves, are listed on the pareto surface. Appropriate setting can be chosen under a balance between two criteria for different control purposes. A controller tuning problem for a plant with high order and time delay is chosen as an example. Simulation results show that the method of MOGA is more efficient compared with traditional tuning methods.展开更多
Fluorescent light-up probes comprising a tetraphenylethene unit with aggregation-induced emission(AIE)characteristics and a water-soluble peptide have been designed and synthesized which provide cell membrane and nucl...Fluorescent light-up probes comprising a tetraphenylethene unit with aggregation-induced emission(AIE)characteristics and a water-soluble peptide have been designed and synthesized which provide cell membrane and nuclear permeability to live cells.This strategy has offered new opportunities for the development of probes with light-up ability and good signal-to-noise ratio.The selectivity or targeting specificity is determined by the peptide sequence,i.e.a nuclear localization signal that leads to nucleus imaging and a cell biomarker targeting peptide that offers specific light-up imaging of HT-29 cells.展开更多
基金Sponsored by the National Natural Science Foundation of China (Grant No. 60504033)
文摘To get the satisfying performance of a PID controller, this paper presents a novel Pareto-based multi-objective genetic algorithm (MOGA), which can be used to find the appropriate setting of the PID controller by analyzing the pareto optimal surfaces. Rated settings of the controller by two criteria, the error between output and reference signals and control moves, are listed on the pareto surface. Appropriate setting can be chosen under a balance between two criteria for different control purposes. A controller tuning problem for a plant with high order and time delay is chosen as an example. Simulation results show that the method of MOGA is more efficient compared with traditional tuning methods.
基金the Singapore National Research Foundation(R279-000-444-281)the Singapore-MIT Alliance for Research and Technology(R279-000-378-592)the Economic Development Board(Singapore-Peking-Oxford Research Enterprise,COY-15EWI-RCFSA/N197-1)
文摘Fluorescent light-up probes comprising a tetraphenylethene unit with aggregation-induced emission(AIE)characteristics and a water-soluble peptide have been designed and synthesized which provide cell membrane and nuclear permeability to live cells.This strategy has offered new opportunities for the development of probes with light-up ability and good signal-to-noise ratio.The selectivity or targeting specificity is determined by the peptide sequence,i.e.a nuclear localization signal that leads to nucleus imaging and a cell biomarker targeting peptide that offers specific light-up imaging of HT-29 cells.