轻子散射实验是探索核子与原子核结构的理想工具。中国电子离子对撞机(Electron Ion Collider in China,EicC)建议书设想在已开建的强流重离子加速器装置(High Intensity heavy ion Accelerator Facility,HIAF)的基础上,升级质子束流为2...轻子散射实验是探索核子与原子核结构的理想工具。中国电子离子对撞机(Electron Ion Collider in China,EicC)建议书设想在已开建的强流重离子加速器装置(High Intensity heavy ion Accelerator Facility,HIAF)的基础上,升级质子束流为20 GeV的极化束流,并建造2.8~5 GeV极化电子束流,从而实现质心系能量为15~20 GeV的双极化电子-离子对撞。EicC设计的亮度为(2~4)×10^33cm^-2·s^-1,质子束流极化率达到70%,电子束流极化率达到80%。该装置除了能提供极化轻离子束流(例如:氦-3)外,也可产生非极化重离子束流(碳-12~铀-238)。EicC将聚焦核子海夸克部分子结构、原子核物质结构与性质、奇特强子态三个方面的物理研究。高亮度、高精度的对撞机有助于精确地测量核子结构函数并对核子进行三维成像,揭示强相互作用的动力学规律;原子核部分子分布包括核子短程关联以及原子核介质效应同样是该提案的重要科学目标;EicC能区接近重味夸克产生阈值,在研究重味强子谱方面拥有低背景的独特优势,有助于发现研究新的奇特强子态。质子质量起源问题也可以通过重味矢量介子的产生来研究。为了完成上述物理目标,我们将利用最先进的探测器技术建造接近全立体角覆盖的EicC对撞机谱仪。在准备EicC白皮书的过程中,我们得到世界各国专家的支持。EicC的物理与已有的实验和美国即将建设的EIC中的物理项目相互补充。EicC的建成及运行有望引领前沿的中高能核物理研究,使我国在加速器和探测器先进技术等领域实现跨越式发展,为我国核物理与强子物理以及相关科学领域提供大型综合实验平台与人才培养基地。展开更多
Actin can be found in all kinds of eukaryotic cells, maintaining their shapes and motilities, while its dynamics in sperm cells is understood less than their nonmuscle somatic cell counterparts. Spermatogenesis is a c...Actin can be found in all kinds of eukaryotic cells, maintaining their shapes and motilities, while its dynamics in sperm cells is understood less than their nonmuscle somatic cell counterparts. Spermatogenesis is a complicated process, resulting in the production of mature sperm from primordial germ cell. Significant structural and biochemical changes take place in the seminif-erous epithelium of the adult testis during spermatogenesis. It was proved that all mammalian sperm contain actin, and that F-actin may play an important role during spermatogenesis, especially in nuclear shaping. Recently a new model for sperm head elonga-tion based on the acrosome-acroplaxome-manchette complex has been proposed. In Drosophila, F-actin assembly is supposed to be very crucial during individualization. In this mini-review, we provide an overview of the structure, function, and regulation characteristics of actin cytoskeleton, and a summary of the current status of research of actin-based structure and movement is also provided, with emphasis on the role of actins in sperm head shaping during spermiogenesis and the cell junction dynamics in the testis. Research of the Sertoli ectoplasmic specialization is in the spotlight, which is a testis-specific actin-based junction very important for the movement of germ cells across the epithelium. Study of the molecular architecture and the regulating mechanism of the Sertoli ectoplasmic specialization has become an intriguing field. All this may lead to a new strategy for male infertility and, at the same time, a novel idea may result in devising much safer contraception with high efficiency. It is hoped that the advances listed in this review would give developmental and morphological researchers a favorable investigating outline and could help to enlarge the view of new strategies and models for actin dynamics during spermatogenesis.展开更多
Two different isospin splittings of nucleon effective mass in nuclear medium as the form of mn*>mp* and mn*<mp* have been implemented in an isospin and momentum dependent transport model.Their impacts on the iso...Two different isospin splittings of nucleon effective mass in nuclear medium as the form of mn*>mp* and mn*<mp* have been implemented in an isospin and momentum dependent transport model.Their impacts on the isospin emission in heavy-ion collisions is investigated thoroughly.It is found that the yield ratios of energetic neutrons to protons squeezed out during the compression stage of two colliding nuclides are sensitive to the isospin splitting.The elliptic flows of free nucleons are also to be promising observables for extracting the nucleon effective mass splitting.Further experimental measurements are being expected,in particular at the CSR-CEE platform in Lanzhou.Several observables are proposed for constraining the density dependence of symmetry energy,such as the transverse flow difference of neutrons and protons,double ratios of n/p and π-/π+,excitation functions of π-/π+ and K0/K+.展开更多
A new version of improved quantum molecular dynamics model that includes standard Skyrme interactions has been developed.Based on the new code,four commonly used parameter sets,SLy4,SkI2,SkM*and Gs are adopted in the ...A new version of improved quantum molecular dynamics model that includes standard Skyrme interactions has been developed.Based on the new code,four commonly used parameter sets,SLy4,SkI2,SkM*and Gs are adopted in the improved quantum molecular dynamics model and the isospin sensitive observables,namely isospin transport ratios,single and double ratios of the yields of neutrons and protons are investigated.The isospin transport ratios are strongly sensitive to the slope of symmetry energy,and are not very sensitive to the nucleon effective mass splitting.On the other hand,the high energy neutrons and protons yields ratios from reactions at different incident energies provide a good observable to the momentum dependence of nucleon effective mass splitting.By comparing our calculations with the data,we find that the constrained L value(the slope of density dependence of symmetry energy) is about ~46 MeV when the Skyrme type interaction is considered in transport models,and the isospin diffusion data prefer to mn*>mp*,but it is not a strong constraint with deep χ2minimum.展开更多
According to Wick's theorem, the second order self-energy corrections of hadrons in the hot and dense nuclear matter are calculated. Furthermore, the Feynman rules are summarized, and an effective formulation on quan...According to Wick's theorem, the second order self-energy corrections of hadrons in the hot and dense nuclear matter are calculated. Furthermore, the Feynman rules are summarized, and an effective formulation on quantum hadrodynamics at finite temperatures and densities is evauated. As the strong couplings between nucleons are considered, the self-consistency of this method is discussed in the framework of relativistic mean-field approximation. Debye screening masses of the scalar and vector mesons in the hot and dense nuclear matter are calculated with this method in the relativistic mean-field approximation. The results are different from those of thermofield dynamics and Brown-Rho conjecture. Moreover, the effective masses of the photon and the nucleon in the hot and dense nuclear matter are discussed.展开更多
The proton nuclear magnetic resonance spectroscopy (1H-NMR), the synchronous fluorescence spectrometry (SFS) and the ruthenium ions catalyzed oxidation (RICO) method were used to determine the chemical structure...The proton nuclear magnetic resonance spectroscopy (1H-NMR), the synchronous fluorescence spectrometry (SFS) and the ruthenium ions catalyzed oxidation (RICO) method were used to determine the chemical structure of polyaromatic nucleus in Oman residue fractions. The results of 1H-NMR analyses showed that the average numbers of aromatic rings in the aromatics, resins and asphaltenes units were 3.2, 5.6 and 8.2, respectively. SFS was used to investigate the distribution of aromatic rings in residue fractions, the main distribution range of aromatic rings in aromatics, resins and asphaltenes were 3 4 rings, 3--5 rings and more than 5 rings, respectively. The aromatic network in residue fractions was oxidized to produce numerous carboxylic acids. The types and content of benzenepolycarboxylic acids, such as phthalic acid, benzenetricarboxylic acids, benzenetetracarboxylic acids, benzenepentacarboxylic acid and benzenehexacarboxylic acid disclosed the condensed types of aromatic nuclei in the core. The biphenyl fraction (BIPH), the cata-condensed fraction (CATA), the peri-condensed fraction (PERI) and the condensed index (BCI) were calculated based on the benzenepolycarboxylic acids formed. The results implied that there was less biphenyl type structures in all residue fractions. The aromatics fraction was almost composed of the cata-condensed type system, and the asphaltenes fraction was wholly composed of the peri-condensed type system, while in the resins fraction co-existed the two types, herein the peri-con- densed type was predominant over the cata-condensed type. Based on the analytical results obtained in the study, the components --aromatics, resins and asphaltenes -- were given the likely structural models.展开更多
The sigma meson production in p + ^12C and p A- ^40Ca reactions at the incident energy Ep = 1.5 GeV is investigated within the Quantum Molecular Dynamics model. The simulation results indicate a distinctive A depende...The sigma meson production in p + ^12C and p A- ^40Ca reactions at the incident energy Ep = 1.5 GeV is investigated within the Quantum Molecular Dynamics model. The simulation results indicate a distinctive A dependence of the sigma production, that is, the increase of A is followed by an increase of the production cross sections. We find that the σ meson production in proton-induced reactions is strongly medium-dependent, and the produced σ mesons decaying in a denser medium experience a stronger mass shift towards lower masses. This mass shift is an experimentally accessible observable in the final state pion pairs, which do not suffer from reabsorption by the surrounding nucleons. It is pointed out that the ratio of measured sigma cross sections as a function of the sigma invariant-mass from various reactions is a good probe to explore the existence of the σ meson in a dense nuclear environment.展开更多
The three-body force effects on the equation of state and its iso-spin dependence of asymmetric nuclear matter and on the proton fraction in neutron star matter have been investigated within Brueckner-Hartree-Fock app...The three-body force effects on the equation of state and its iso-spin dependence of asymmetric nuclear matter and on the proton fraction in neutron star matter have been investigated within Brueckner-Hartree-Fock approach by using a microscopic three-body force. It is shown that, even in the presence of the three-body force, the empirical parabolic law of the energy per nucleon vs. isospin asymmetry is fulfilled in the whole asymmetry range and also up to high density. The three-body force provides a strong enhancement of symmetry energy at high density in agreement with relativistic approaches. It also shows that the three-body force leads to a much more rapid increasing of symmetry energy with density in relatively high density region and to a much lower threshold density for the direct URCA process to occur in a neutron star as compared to the predictions adopting only pure two-body force.展开更多
Our previous studies showed a predominance of high molecular weight protein group in tumor nuclear matrices. Contrary to normal cells, proteins of this group are preferentially phosphorylated. Phosphoproteins of hepat...Our previous studies showed a predominance of high molecular weight protein group in tumor nuclear matrices. Contrary to normal cells, proteins of this group are preferentially phosphorylated. Phosphoproteins of hepatoma nuclear matrix are selectively subjected to rapid proteolysis. By alkali treatment and a monoclonal antibody against phosphotyrosyl residue the presence of two high molecular weight bands of phosphotyrosyl-containing proteins was detected in nuclear matrices of tumor but not of normal liver cells. High molecular weight protein group of tumor nuclear matrices revealed also a rapid turnover and preferential incorporation of labeled amino acids selectively inhibited by chloramphenicol.展开更多
We propose a quantization procedure for the nucleon-scMar meson system, in which an arbitrary mean scalar meson field Ф is introduced. The equivalence of this procedure with the usual one is proven for any given valu...We propose a quantization procedure for the nucleon-scMar meson system, in which an arbitrary mean scalar meson field Ф is introduced. The equivalence of this procedure with the usual one is proven for any given value of qS. By use of this procedure, the scalar meson field in the Walecka's MFA and in Chin's RHA are quantized around the mean field, Its corrections on these theories are considered by perturbation up to the second order. The arbitrariness of Ф makes us free to fix it at any stage in the calculation. When we fix it in the way of Walecka's MFA, the quantum corrections are big, and the result does not converge. When we fix it in the way of Chin's RHA, the quantum correction is negligibly small, and the convergence is excellent. It shows that RHA covers the leading part of quantum field theory for nuclear systems and is an excellent zeroth order approximation for further quantum corrections, while the Walecka's MFA does not. We suggest to fix the parameter Ф at the end of the whole calculation by minimizing the total energy per-nucleon for the nuclear matter or the total energy for the finite nucleus, to make the quantized relativistic mean field theory (QRMFT) a variational method.展开更多
In the Hellings Nordtvedt theory, we obtain some expressions of energy radiation and mass defect effect for a kind of the active galactic nuclei, which is meaningful to calculating the energy radiation in the processi...In the Hellings Nordtvedt theory, we obtain some expressions of energy radiation and mass defect effect for a kind of the active galactic nuclei, which is meaningful to calculating the energy radiation in the procession of forming this kind of celestial bodies. This calculation can give some interpretation for energy source of the jet from the active galactic nuclei.展开更多
The study of finite nuclei containing antibaryon(s) in addition to nucleons is an interesting topic in nuclear physics. The calculation of the lifetime of an antibaryon embedded in a nucleus was performed in the fra...The study of finite nuclei containing antibaryon(s) in addition to nucleons is an interesting topic in nuclear physics. The calculation of the lifetime of an antibaryon embedded in a nucleus was performed in the framework of the standard quantum field theory. It was shown that the annihilation probability of the antibaryon in nuclei is strongly dependent on the effective masses of mesons involved in the annihilation channels. The contribution of the Dirac sea to the annihilation probability makes the lifetime of the antibaryon short. If the Dirac sea effect is neglected, the lifetime of the bound antibaryon tends to be longer with the nuclear density increasing. Particularly, when the nuclear density is larger than a critical value, the antibaryon may exist stably in a nucleus.展开更多
文摘轻子散射实验是探索核子与原子核结构的理想工具。中国电子离子对撞机(Electron Ion Collider in China,EicC)建议书设想在已开建的强流重离子加速器装置(High Intensity heavy ion Accelerator Facility,HIAF)的基础上,升级质子束流为20 GeV的极化束流,并建造2.8~5 GeV极化电子束流,从而实现质心系能量为15~20 GeV的双极化电子-离子对撞。EicC设计的亮度为(2~4)×10^33cm^-2·s^-1,质子束流极化率达到70%,电子束流极化率达到80%。该装置除了能提供极化轻离子束流(例如:氦-3)外,也可产生非极化重离子束流(碳-12~铀-238)。EicC将聚焦核子海夸克部分子结构、原子核物质结构与性质、奇特强子态三个方面的物理研究。高亮度、高精度的对撞机有助于精确地测量核子结构函数并对核子进行三维成像,揭示强相互作用的动力学规律;原子核部分子分布包括核子短程关联以及原子核介质效应同样是该提案的重要科学目标;EicC能区接近重味夸克产生阈值,在研究重味强子谱方面拥有低背景的独特优势,有助于发现研究新的奇特强子态。质子质量起源问题也可以通过重味矢量介子的产生来研究。为了完成上述物理目标,我们将利用最先进的探测器技术建造接近全立体角覆盖的EicC对撞机谱仪。在准备EicC白皮书的过程中,我们得到世界各国专家的支持。EicC的物理与已有的实验和美国即将建设的EIC中的物理项目相互补充。EicC的建成及运行有望引领前沿的中高能核物理研究,使我国在加速器和探测器先进技术等领域实现跨越式发展,为我国核物理与强子物理以及相关科学领域提供大型综合实验平台与人才培养基地。
基金Project (No. 30671606) supported by the National Natural Science Foundation of China
文摘Actin can be found in all kinds of eukaryotic cells, maintaining their shapes and motilities, while its dynamics in sperm cells is understood less than their nonmuscle somatic cell counterparts. Spermatogenesis is a complicated process, resulting in the production of mature sperm from primordial germ cell. Significant structural and biochemical changes take place in the seminif-erous epithelium of the adult testis during spermatogenesis. It was proved that all mammalian sperm contain actin, and that F-actin may play an important role during spermatogenesis, especially in nuclear shaping. Recently a new model for sperm head elonga-tion based on the acrosome-acroplaxome-manchette complex has been proposed. In Drosophila, F-actin assembly is supposed to be very crucial during individualization. In this mini-review, we provide an overview of the structure, function, and regulation characteristics of actin cytoskeleton, and a summary of the current status of research of actin-based structure and movement is also provided, with emphasis on the role of actins in sperm head shaping during spermiogenesis and the cell junction dynamics in the testis. Research of the Sertoli ectoplasmic specialization is in the spotlight, which is a testis-specific actin-based junction very important for the movement of germ cells across the epithelium. Study of the molecular architecture and the regulating mechanism of the Sertoli ectoplasmic specialization has become an intriguing field. All this may lead to a new strategy for male infertility and, at the same time, a novel idea may result in devising much safer contraception with high efficiency. It is hoped that the advances listed in this review would give developmental and morphological researchers a favorable investigating outline and could help to enlarge the view of new strategies and models for actin dynamics during spermatogenesis.
基金Supported by National Natural Science Foundation of China(NSFC) projects (No.11175218)the Advancement Society of Young Innovation of Chinese Academy of Sciences
文摘Two different isospin splittings of nucleon effective mass in nuclear medium as the form of mn*>mp* and mn*<mp* have been implemented in an isospin and momentum dependent transport model.Their impacts on the isospin emission in heavy-ion collisions is investigated thoroughly.It is found that the yield ratios of energetic neutrons to protons squeezed out during the compression stage of two colliding nuclides are sensitive to the isospin splitting.The elliptic flows of free nucleons are also to be promising observables for extracting the nucleon effective mass splitting.Further experimental measurements are being expected,in particular at the CSR-CEE platform in Lanzhou.Several observables are proposed for constraining the density dependence of symmetry energy,such as the transverse flow difference of neutrons and protons,double ratios of n/p and π-/π+,excitation functions of π-/π+ and K0/K+.
基金Supported by National Natural Science Foundation of China(NSFC) projects (Nos.11075215,10875031,11005022,11005155 and 11275052)973 Program of China(No.2013CB834404)National Science Foundation(Grants No.PHY-0606007)
文摘A new version of improved quantum molecular dynamics model that includes standard Skyrme interactions has been developed.Based on the new code,four commonly used parameter sets,SLy4,SkI2,SkM*and Gs are adopted in the improved quantum molecular dynamics model and the isospin sensitive observables,namely isospin transport ratios,single and double ratios of the yields of neutrons and protons are investigated.The isospin transport ratios are strongly sensitive to the slope of symmetry energy,and are not very sensitive to the nucleon effective mass splitting.On the other hand,the high energy neutrons and protons yields ratios from reactions at different incident energies provide a good observable to the momentum dependence of nucleon effective mass splitting.By comparing our calculations with the data,we find that the constrained L value(the slope of density dependence of symmetry energy) is about ~46 MeV when the Skyrme type interaction is considered in transport models,and the isospin diffusion data prefer to mn*>mp*,but it is not a strong constraint with deep χ2minimum.
基金The project supported by the Foundations of Beijing University of Technology and Ren-Cai-Qiang-Jiao Foundation of Beijing Municipal Education Commission
文摘According to Wick's theorem, the second order self-energy corrections of hadrons in the hot and dense nuclear matter are calculated. Furthermore, the Feynman rules are summarized, and an effective formulation on quantum hadrodynamics at finite temperatures and densities is evauated. As the strong couplings between nucleons are considered, the self-consistency of this method is discussed in the framework of relativistic mean-field approximation. Debye screening masses of the scalar and vector mesons in the hot and dense nuclear matter are calculated with this method in the relativistic mean-field approximation. The results are different from those of thermofield dynamics and Brown-Rho conjecture. Moreover, the effective masses of the photon and the nucleon in the hot and dense nuclear matter are discussed.
文摘The proton nuclear magnetic resonance spectroscopy (1H-NMR), the synchronous fluorescence spectrometry (SFS) and the ruthenium ions catalyzed oxidation (RICO) method were used to determine the chemical structure of polyaromatic nucleus in Oman residue fractions. The results of 1H-NMR analyses showed that the average numbers of aromatic rings in the aromatics, resins and asphaltenes units were 3.2, 5.6 and 8.2, respectively. SFS was used to investigate the distribution of aromatic rings in residue fractions, the main distribution range of aromatic rings in aromatics, resins and asphaltenes were 3 4 rings, 3--5 rings and more than 5 rings, respectively. The aromatic network in residue fractions was oxidized to produce numerous carboxylic acids. The types and content of benzenepolycarboxylic acids, such as phthalic acid, benzenetricarboxylic acids, benzenetetracarboxylic acids, benzenepentacarboxylic acid and benzenehexacarboxylic acid disclosed the condensed types of aromatic nuclei in the core. The biphenyl fraction (BIPH), the cata-condensed fraction (CATA), the peri-condensed fraction (PERI) and the condensed index (BCI) were calculated based on the benzenepolycarboxylic acids formed. The results implied that there was less biphenyl type structures in all residue fractions. The aromatics fraction was almost composed of the cata-condensed type system, and the asphaltenes fraction was wholly composed of the peri-condensed type system, while in the resins fraction co-existed the two types, herein the peri-con- densed type was predominant over the cata-condensed type. Based on the analytical results obtained in the study, the components --aromatics, resins and asphaltenes -- were given the likely structural models.
基金National Natural Science Foundation of China under Grant Nos.10435080,10575075,and 10447006the Deutsche Forschungsgemeinschaft under Grant No.446CHV-113/91/1-3the National Research Concil of Thailand under Grant No.1.CH5/2549
文摘The sigma meson production in p + ^12C and p A- ^40Ca reactions at the incident energy Ep = 1.5 GeV is investigated within the Quantum Molecular Dynamics model. The simulation results indicate a distinctive A dependence of the sigma production, that is, the increase of A is followed by an increase of the production cross sections. We find that the σ meson production in proton-induced reactions is strongly medium-dependent, and the produced σ mesons decaying in a denser medium experience a stronger mass shift towards lower masses. This mass shift is an experimentally accessible observable in the final state pion pairs, which do not suffer from reabsorption by the surrounding nucleons. It is pointed out that the ratio of measured sigma cross sections as a function of the sigma invariant-mass from various reactions is a good probe to explore the existence of the σ meson in a dense nuclear environment.
文摘The three-body force effects on the equation of state and its iso-spin dependence of asymmetric nuclear matter and on the proton fraction in neutron star matter have been investigated within Brueckner-Hartree-Fock approach by using a microscopic three-body force. It is shown that, even in the presence of the three-body force, the empirical parabolic law of the energy per nucleon vs. isospin asymmetry is fulfilled in the whole asymmetry range and also up to high density. The three-body force provides a strong enhancement of symmetry energy at high density in agreement with relativistic approaches. It also shows that the three-body force leads to a much more rapid increasing of symmetry energy with density in relatively high density region and to a much lower threshold density for the direct URCA process to occur in a neutron star as compared to the predictions adopting only pure two-body force.
文摘Our previous studies showed a predominance of high molecular weight protein group in tumor nuclear matrices. Contrary to normal cells, proteins of this group are preferentially phosphorylated. Phosphoproteins of hepatoma nuclear matrix are selectively subjected to rapid proteolysis. By alkali treatment and a monoclonal antibody against phosphotyrosyl residue the presence of two high molecular weight bands of phosphotyrosyl-containing proteins was detected in nuclear matrices of tumor but not of normal liver cells. High molecular weight protein group of tumor nuclear matrices revealed also a rapid turnover and preferential incorporation of labeled amino acids selectively inhibited by chloramphenicol.
基金Supported by the Nature Science Foundation of China under Grant Nos.10875003 and 10811240152the calculations are supported by CERNET High Performance Computing Center in China
文摘We propose a quantization procedure for the nucleon-scMar meson system, in which an arbitrary mean scalar meson field Ф is introduced. The equivalence of this procedure with the usual one is proven for any given value of qS. By use of this procedure, the scalar meson field in the Walecka's MFA and in Chin's RHA are quantized around the mean field, Its corrections on these theories are considered by perturbation up to the second order. The arbitrariness of Ф makes us free to fix it at any stage in the calculation. When we fix it in the way of Walecka's MFA, the quantum corrections are big, and the result does not converge. When we fix it in the way of Chin's RHA, the quantum correction is negligibly small, and the convergence is excellent. It shows that RHA covers the leading part of quantum field theory for nuclear systems and is an excellent zeroth order approximation for further quantum corrections, while the Walecka's MFA does not. We suggest to fix the parameter Ф at the end of the whole calculation by minimizing the total energy per-nucleon for the nuclear matter or the total energy for the finite nucleus, to make the quantized relativistic mean field theory (QRMFT) a variational method.
基金The project supported by National Natural Science Foundation of China under Grant No.19975018+2 种基金National Basic Research Program of China under Grant No.2003CB716300Natural Science Foundation of Hunan Province of China under Grant No.01JJY2084
文摘In the Hellings Nordtvedt theory, we obtain some expressions of energy radiation and mass defect effect for a kind of the active galactic nuclei, which is meaningful to calculating the energy radiation in the procession of forming this kind of celestial bodies. This calculation can give some interpretation for energy source of the jet from the active galactic nuclei.
基金Supported by National Natural Science Foundation of China under Grant No.10775059Specialized Research Fand for the Doctoral Program of Higher Education of China under Grant No.20070183133
文摘The study of finite nuclei containing antibaryon(s) in addition to nucleons is an interesting topic in nuclear physics. The calculation of the lifetime of an antibaryon embedded in a nucleus was performed in the framework of the standard quantum field theory. It was shown that the annihilation probability of the antibaryon in nuclei is strongly dependent on the effective masses of mesons involved in the annihilation channels. The contribution of the Dirac sea to the annihilation probability makes the lifetime of the antibaryon short. If the Dirac sea effect is neglected, the lifetime of the bound antibaryon tends to be longer with the nuclear density increasing. Particularly, when the nuclear density is larger than a critical value, the antibaryon may exist stably in a nucleus.