目的利用OPD-SCAN波前像差分析仪检查和分析近视眼患者准分子激光原位角膜磨镶术(laser in situ keratomileusis,LASIK)术后全眼和角膜前表面球面像差的改变。方法连续选取患者40例73眼进行手术前后波前像差检查,分低、中、高3个屈光度...目的利用OPD-SCAN波前像差分析仪检查和分析近视眼患者准分子激光原位角膜磨镶术(laser in situ keratomileusis,LASIK)术后全眼和角膜前表面球面像差的改变。方法连续选取患者40例73眼进行手术前后波前像差检查,分低、中、高3个屈光度组,计算出6mm瞳孔直径全眼和角膜前表面的球面像差值:(1)各组内术前、术后1周、术后3个月的球面像差比较采用单向方差分析,并用Post Hoc Tests进行两两比较;(2)术前屈光度和术后球面像差采用直线相关分析;(3)全眼和角膜前表面术后3个月球面像差较术前的变化采用t检验分析。结果低、中、高度各组术前、术后1周和术后3个月全眼和角膜前表面球面像差均方根值经比较差异有统计学意义(P<0.01)。术后1周和术后3个月的全眼和角膜前表面的球面像差均方根值均与术前屈光度(绝对值)呈正相关(P<0.01)。低、中、高度组全眼和角膜前表面术后3个月球面像差与术前球面像差的差值经比较差异有统计学意义(P<0.05)。结论LASIK术后全眼和角膜前表面的球面像差显著增加,并与术前屈光度(绝对值)呈正相关。LASIK术后全眼和角膜前表面的球面像差的增加是不同步的,以角膜前表面的球面像差增加更为显著。展开更多
【目的】观察不同年龄段人群实测与6.0 mm瞳孔直径下全角膜和前角膜球面像差的差异。【方法】观察不同年龄段(20~29, 30~39, 40~49, 50~59, 60~69, 70~79)共100例受试者,通过Sirius眼前节分析系统检测不同瞳孔直径下(2.0 mm, 2.5 mm, 3....【目的】观察不同年龄段人群实测与6.0 mm瞳孔直径下全角膜和前角膜球面像差的差异。【方法】观察不同年龄段(20~29, 30~39, 40~49, 50~59, 60~69, 70~79)共100例受试者,通过Sirius眼前节分析系统检测不同瞳孔直径下(2.0 mm, 2.5 mm, 3.0 mm, 3.5 mm, 4.0 mm, 4.5 mm, 5.0 mm, 5.5 mm, 6.0 mm, 6.5 mm, 7.0 mm)全角膜和前角膜球面像差及暗环境下实测瞳孔直径,通过数学拟合曲线计算出该实测瞳孔直径下全角膜和前角膜的球面像差值,分别比较其与6.0 mm瞳孔直径下全角膜与前角膜球面像差之间的差异。【结果】实测瞳孔直径与年龄呈负相关(P 0.05)。在60~69,70~79年龄段,实测全角膜和前角膜球面像差均显著低于6.0 mm瞳孔直径下对应参数(P 【0.05)。在20~29,30~39,70~79年龄段,实测全角膜与前角膜球面像差间有显著性差异(P 【0.05);在6.0 mm瞳孔直径下,全角膜球面像差值在30~39,40~49,60~69年龄段显著低于前角膜对应值(P 【0.05)。【结论】老年人群中实测瞳孔直径下全和前角膜球面像差均显著小于6.0 mm瞳孔直径下对应参数,此差异与老年人群实际平均瞳孔直径较小有关。在实测和6.0 mm瞳孔直径下,全与前角膜球面像差在部分年龄段存在差异,两者有显著性差异的年龄段分布不同。所测前角膜球面像差不能完全代替全角膜球面像差,建议以实测全角膜球面像差值作为白内障手术选择消球差人工晶状体类型的依据。展开更多
Purpose: To compare differences in subjective glare and spherical aberration b etween five foldable intraocular lenses (IOLs) made of different materials and t o different designs. Methods: This prospective study comp...Purpose: To compare differences in subjective glare and spherical aberration b etween five foldable intraocular lenses (IOLs) made of different materials and t o different designs. Methods: This prospective study comprised 175 cataract pati ents who underwent phacoemulsification and were randomized to receive one of fiv e types of foldable IOL (AcrySof. MA30BA, Alcon; Sensar. AR40, AMO; AcrySof. SA3 0AL, Alcon; Sensar. AR40e, AMO, and Tecnis. Z9000, Pharmacia &Upjohn). All pati ents received a questionnaire investigating the incidence of subjective photic p henomena. Two months postoperatively, we collected data regarding subjective gla re and evaluated pupil size, visual acuity and wavefront aberration of the corne a and eye. Results: With regard to difficulty in performing ordinary activities under different light conditions and light and dark adaptation, the difference b etween the groups was not significant (p >0.05, chi-squared test). With respect to difficulty in driving at night, the MA30BA group had a significant higher in cidence of photic phenomena than the SA30AL, AR40e and Z9000 groups (p < 0.05, c hi-squared test). Wavefront measurements revealed a significant difference betw een the Z9000, AR40e and SA30AL groups, which showed the lowest values, and the MA30BA group, which showed the highest value (p< 0.05, ANOVA with Tamhane postho c test). Conclusions: New generation IOLs such as the Pharmacia Z9000, AMO AR40e and AcrySof. SA30AL have a lower incidence of glare and spherical aberrations; however, their impact on future IOL design should be conditioned by further data , especially regarding posterior capsule opacification.展开更多
目的比较个性化选择0、-0.20μm、-0.27μm三种不同球差非球面人工晶状体(intraocular lens,IOL)及其随机植入术后的视觉质量,探讨最佳矫正球差值。方法前瞻性病例对照研究。选取就诊于我科的白内障患者125例(145眼),术前使用i Trace全...目的比较个性化选择0、-0.20μm、-0.27μm三种不同球差非球面人工晶状体(intraocular lens,IOL)及其随机植入术后的视觉质量,探讨最佳矫正球差值。方法前瞻性病例对照研究。选取就诊于我科的白内障患者125例(145眼),术前使用i Trace全视觉功能分析仪测量角膜高阶像差,根据角膜球差(spherical aberation,SA)值的不同分为A、B、C三组,分别植入三种不同SA非球面IOL,对照组(D组)随机植入非球面IOL。术后3个月分析全眼及角膜的高阶像差、调制传递函数(modulation transfer function,MTF)、斯泰尔比值(Strehl ratio,SR)、最佳矫正视力(best corrected visual acuity,BCVA)。结果 (1)手术前后角膜SA差异无统计学意义(P>0.05),全眼慧差(Coma)、三叶草差(Trefoil)及总高阶像差(total high order aherration,t HOA)手术前后的变化与角膜SA的变化相似。(2)三组患者BCVA差异无统计学意义(P>0.05)。(3)3 mm瞳孔直径下,四组IOL眼的角膜SA、全眼MTF t HOA及SR差异均无统计学意义(均为P>0.05);全眼SA差异有统计学意义(P=0.019),A组、B组、C组间差异无统计学意义(P>0.05),但均<D组(P=0.000)。(4)5 mm瞳孔直径下,四组IOL眼角膜SA差异无统计学意义(P>0.05);全眼SA、t HOA差异均有统计学意义(均为P=0.000),A、B、C三组间差异无统计学意义(P>0.05),但均<D组(P=0.000);全眼MTF t HOA及SR差异均有统计学意义(均为P<0.05),A、B、C三组间差异无统计学意义(P>0.05),但均>D组(P=0.000)。结论超声乳化白内障吸出术前后角膜高阶像差无差异。小瞳孔直径下,不同SA设计非球面IOL眼术后视觉质量比较无差异。大瞳孔直径下,根据术前SA个性化选择较随机植入非球面IOL眼可获得较好的视觉质量。展开更多
文摘目的利用OPD-SCAN波前像差分析仪检查和分析近视眼患者准分子激光原位角膜磨镶术(laser in situ keratomileusis,LASIK)术后全眼和角膜前表面球面像差的改变。方法连续选取患者40例73眼进行手术前后波前像差检查,分低、中、高3个屈光度组,计算出6mm瞳孔直径全眼和角膜前表面的球面像差值:(1)各组内术前、术后1周、术后3个月的球面像差比较采用单向方差分析,并用Post Hoc Tests进行两两比较;(2)术前屈光度和术后球面像差采用直线相关分析;(3)全眼和角膜前表面术后3个月球面像差较术前的变化采用t检验分析。结果低、中、高度各组术前、术后1周和术后3个月全眼和角膜前表面球面像差均方根值经比较差异有统计学意义(P<0.01)。术后1周和术后3个月的全眼和角膜前表面的球面像差均方根值均与术前屈光度(绝对值)呈正相关(P<0.01)。低、中、高度组全眼和角膜前表面术后3个月球面像差与术前球面像差的差值经比较差异有统计学意义(P<0.05)。结论LASIK术后全眼和角膜前表面的球面像差显著增加,并与术前屈光度(绝对值)呈正相关。LASIK术后全眼和角膜前表面的球面像差的增加是不同步的,以角膜前表面的球面像差增加更为显著。
文摘【目的】观察不同年龄段人群实测与6.0 mm瞳孔直径下全角膜和前角膜球面像差的差异。【方法】观察不同年龄段(20~29, 30~39, 40~49, 50~59, 60~69, 70~79)共100例受试者,通过Sirius眼前节分析系统检测不同瞳孔直径下(2.0 mm, 2.5 mm, 3.0 mm, 3.5 mm, 4.0 mm, 4.5 mm, 5.0 mm, 5.5 mm, 6.0 mm, 6.5 mm, 7.0 mm)全角膜和前角膜球面像差及暗环境下实测瞳孔直径,通过数学拟合曲线计算出该实测瞳孔直径下全角膜和前角膜的球面像差值,分别比较其与6.0 mm瞳孔直径下全角膜与前角膜球面像差之间的差异。【结果】实测瞳孔直径与年龄呈负相关(P 0.05)。在60~69,70~79年龄段,实测全角膜和前角膜球面像差均显著低于6.0 mm瞳孔直径下对应参数(P 【0.05)。在20~29,30~39,70~79年龄段,实测全角膜与前角膜球面像差间有显著性差异(P 【0.05);在6.0 mm瞳孔直径下,全角膜球面像差值在30~39,40~49,60~69年龄段显著低于前角膜对应值(P 【0.05)。【结论】老年人群中实测瞳孔直径下全和前角膜球面像差均显著小于6.0 mm瞳孔直径下对应参数,此差异与老年人群实际平均瞳孔直径较小有关。在实测和6.0 mm瞳孔直径下,全与前角膜球面像差在部分年龄段存在差异,两者有显著性差异的年龄段分布不同。所测前角膜球面像差不能完全代替全角膜球面像差,建议以实测全角膜球面像差值作为白内障手术选择消球差人工晶状体类型的依据。
文摘Purpose: To compare differences in subjective glare and spherical aberration b etween five foldable intraocular lenses (IOLs) made of different materials and t o different designs. Methods: This prospective study comprised 175 cataract pati ents who underwent phacoemulsification and were randomized to receive one of fiv e types of foldable IOL (AcrySof. MA30BA, Alcon; Sensar. AR40, AMO; AcrySof. SA3 0AL, Alcon; Sensar. AR40e, AMO, and Tecnis. Z9000, Pharmacia &Upjohn). All pati ents received a questionnaire investigating the incidence of subjective photic p henomena. Two months postoperatively, we collected data regarding subjective gla re and evaluated pupil size, visual acuity and wavefront aberration of the corne a and eye. Results: With regard to difficulty in performing ordinary activities under different light conditions and light and dark adaptation, the difference b etween the groups was not significant (p >0.05, chi-squared test). With respect to difficulty in driving at night, the MA30BA group had a significant higher in cidence of photic phenomena than the SA30AL, AR40e and Z9000 groups (p < 0.05, c hi-squared test). Wavefront measurements revealed a significant difference betw een the Z9000, AR40e and SA30AL groups, which showed the lowest values, and the MA30BA group, which showed the highest value (p< 0.05, ANOVA with Tamhane postho c test). Conclusions: New generation IOLs such as the Pharmacia Z9000, AMO AR40e and AcrySof. SA30AL have a lower incidence of glare and spherical aberrations; however, their impact on future IOL design should be conditioned by further data , especially regarding posterior capsule opacification.
文摘目的比较个性化选择0、-0.20μm、-0.27μm三种不同球差非球面人工晶状体(intraocular lens,IOL)及其随机植入术后的视觉质量,探讨最佳矫正球差值。方法前瞻性病例对照研究。选取就诊于我科的白内障患者125例(145眼),术前使用i Trace全视觉功能分析仪测量角膜高阶像差,根据角膜球差(spherical aberation,SA)值的不同分为A、B、C三组,分别植入三种不同SA非球面IOL,对照组(D组)随机植入非球面IOL。术后3个月分析全眼及角膜的高阶像差、调制传递函数(modulation transfer function,MTF)、斯泰尔比值(Strehl ratio,SR)、最佳矫正视力(best corrected visual acuity,BCVA)。结果 (1)手术前后角膜SA差异无统计学意义(P>0.05),全眼慧差(Coma)、三叶草差(Trefoil)及总高阶像差(total high order aherration,t HOA)手术前后的变化与角膜SA的变化相似。(2)三组患者BCVA差异无统计学意义(P>0.05)。(3)3 mm瞳孔直径下,四组IOL眼的角膜SA、全眼MTF t HOA及SR差异均无统计学意义(均为P>0.05);全眼SA差异有统计学意义(P=0.019),A组、B组、C组间差异无统计学意义(P>0.05),但均<D组(P=0.000)。(4)5 mm瞳孔直径下,四组IOL眼角膜SA差异无统计学意义(P>0.05);全眼SA、t HOA差异均有统计学意义(均为P=0.000),A、B、C三组间差异无统计学意义(P>0.05),但均<D组(P=0.000);全眼MTF t HOA及SR差异均有统计学意义(均为P<0.05),A、B、C三组间差异无统计学意义(P>0.05),但均>D组(P=0.000)。结论超声乳化白内障吸出术前后角膜高阶像差无差异。小瞳孔直径下,不同SA设计非球面IOL眼术后视觉质量比较无差异。大瞳孔直径下,根据术前SA个性化选择较随机植入非球面IOL眼可获得较好的视觉质量。