实现大数据基础上的精准医学目标,需要可靠的证据支持、信息技术和产品保障。本文介绍了国外较为成熟的临床决策支持产品:法国居里研究院的无缝信息产品和护理决策支持产品My cancer genome、IBM的Watson及相关的证据研究。建议我国借...实现大数据基础上的精准医学目标,需要可靠的证据支持、信息技术和产品保障。本文介绍了国外较为成熟的临床决策支持产品:法国居里研究院的无缝信息产品和护理决策支持产品My cancer genome、IBM的Watson及相关的证据研究。建议我国借鉴美国方式培养生物信息学高端人才、开放医疗数据共享、制定需求导向的研究战略,科学布局,建设生物信息学基础框架和癌症知识网络,推动基因组、蛋白质组等组学技术研究成果与临床电子病历系统的对接与融合。展开更多
急性肾衰竭是一种发病率较高的临床疾病,尽早识别潜在患者有助于医生对其进行医疗干预,降低发病率和死亡率.近年来,依靠电子健康病历去预测患者潜在的健康风险逐渐受到关注.大多数模型通过聚合数据或者填充缺失值的方式处理人体生理指...急性肾衰竭是一种发病率较高的临床疾病,尽早识别潜在患者有助于医生对其进行医疗干预,降低发病率和死亡率.近年来,依靠电子健康病历去预测患者潜在的健康风险逐渐受到关注.大多数模型通过聚合数据或者填充缺失值的方式处理人体生理指标数据中存在的稀疏性和不规则性问题,忽视了缺失信息隐含的患者健康状态.此外,现有的急性肾衰竭预测模型并没有考虑各种模态的数据特点和模态之间的相关性.为了解决以上问题,提出了基于多模态的急性肾衰竭预测模型.该模型考虑了人体生理指标数据、疾病数据和人口统计学数据.设计了新的基于掩码和时间差的LSTM(long short term memory)网络去学习各个生理指标的时间间隔和缺失信息,捕获指标的数值变化和检测频率变化,引入了多头自注意力机制促进各模态表征的相互学习.在真实的数据集上进行了急性肾衰竭预测问题和死亡风险预测问题的实验,证明了所提出模型的有效性和合理性.展开更多
In order to improve patient care in the United States there,the government made a mandate called HIE(Health Information Exchange).This order was created from the belief that sharing digital health in-formation between...In order to improve patient care in the United States there,the government made a mandate called HIE(Health Information Exchange).This order was created from the belief that sharing digital health in-formation between,across,and within health communities will improve one's healthcare experience across their lifespan.Patient health information,i.e.the personal health record,should be shareable between healthcare providers;such as private practice physicians,home health agencies,hospitals and nursing care facilities.Most of the U.S.hospitals now have electronic health records,however,with a lack of standards for structuring health information and unified communication protocols to share health information across providers,only a small percentage of U.S.hospitals engage in computerized HIE.In order to understand barriers and facilitators in the U.S.of HIE adoption,we reviewed the published research literature between 2010 and 2015.Our search yielded 664 articles from Medline,PsychInfo,Global health,InSpec,Scopus and Business Source Complete databases.Thirty-nine articles met our inclusion criteria.This article presents the compiled organizational and end user barriers and facilitators along with suggested methods to achieve continuity of care through HIE.展开更多
文摘实现大数据基础上的精准医学目标,需要可靠的证据支持、信息技术和产品保障。本文介绍了国外较为成熟的临床决策支持产品:法国居里研究院的无缝信息产品和护理决策支持产品My cancer genome、IBM的Watson及相关的证据研究。建议我国借鉴美国方式培养生物信息学高端人才、开放医疗数据共享、制定需求导向的研究战略,科学布局,建设生物信息学基础框架和癌症知识网络,推动基因组、蛋白质组等组学技术研究成果与临床电子病历系统的对接与融合。
文摘急性肾衰竭是一种发病率较高的临床疾病,尽早识别潜在患者有助于医生对其进行医疗干预,降低发病率和死亡率.近年来,依靠电子健康病历去预测患者潜在的健康风险逐渐受到关注.大多数模型通过聚合数据或者填充缺失值的方式处理人体生理指标数据中存在的稀疏性和不规则性问题,忽视了缺失信息隐含的患者健康状态.此外,现有的急性肾衰竭预测模型并没有考虑各种模态的数据特点和模态之间的相关性.为了解决以上问题,提出了基于多模态的急性肾衰竭预测模型.该模型考虑了人体生理指标数据、疾病数据和人口统计学数据.设计了新的基于掩码和时间差的LSTM(long short term memory)网络去学习各个生理指标的时间间隔和缺失信息,捕获指标的数值变化和检测频率变化,引入了多头自注意力机制促进各模态表征的相互学习.在真实的数据集上进行了急性肾衰竭预测问题和死亡风险预测问题的实验,证明了所提出模型的有效性和合理性.
文摘In order to improve patient care in the United States there,the government made a mandate called HIE(Health Information Exchange).This order was created from the belief that sharing digital health in-formation between,across,and within health communities will improve one's healthcare experience across their lifespan.Patient health information,i.e.the personal health record,should be shareable between healthcare providers;such as private practice physicians,home health agencies,hospitals and nursing care facilities.Most of the U.S.hospitals now have electronic health records,however,with a lack of standards for structuring health information and unified communication protocols to share health information across providers,only a small percentage of U.S.hospitals engage in computerized HIE.In order to understand barriers and facilitators in the U.S.of HIE adoption,we reviewed the published research literature between 2010 and 2015.Our search yielded 664 articles from Medline,PsychInfo,Global health,InSpec,Scopus and Business Source Complete databases.Thirty-nine articles met our inclusion criteria.This article presents the compiled organizational and end user barriers and facilitators along with suggested methods to achieve continuity of care through HIE.
