据英国《BBc新闻》（BBCNEWS）2016-07-23报道，美国休斯顿大学（University of Houston）的一项研究发现，睡眠不足对儿童影响也是深远的，会令儿童成年后更易罹患抑郁症和焦虑症。休斯顿睡眠及焦虑研究中心（Sleep and Anxiety Center...据英国《BBc新闻》（BBCNEWS）2016-07-23报道，美国休斯顿大学（University of Houston）的一项研究发现，睡眠不足对儿童影响也是深远的，会令儿童成年后更易罹患抑郁症和焦虑症。休斯顿睡眠及焦虑研究中心（Sleep and Anxiety Center of Houston, SACH）的研究人员为了研究儿童睡眠对认知、行为及心理的影响，对50名7—11岁儿童进行暂时限制性睡眠实验。展开更多
AIM： To analyze the polygraphic sleep patterns during cirrhosis progression in a rat model by repeated CCh administration. METHODS： Male Wistar rats received three weekly injections of CCl4 for 11 wk, and were analy...AIM： To analyze the polygraphic sleep patterns during cirrhosis progression in a rat model by repeated CCh administration. METHODS： Male Wistar rats received three weekly injections of CCl4 for 11 wk, and were analyzed before and during the induction of cirrhosis. Rats were im- planted with electrodes to record their sleep patterns. Polygraph recordings were made weekly over 11 wk for 8 h, during the light period. After a basal recording, rats received three weekly injections of CCl4. Histological confirmation of cirrhosis was performed after 11 wk. RESULTS： The results showed a progressive decrease in total wake time that reached statistical significance from the second week of treatment. In addition, there was an increase in total time of slow wave sleep （SWS）Ⅱ and rapid eye movement sleep （REM sleep） in most of the 11 wk. SWS I showed no significant variations. During the final weeks, a significant increase in REM sleep frequency was also observed. Histological analyses of the livers showed unequivocal signs of cirrhosis. CONCLUSION： These data suggest that hepatic failure produced by CCh administration is capable of modifying the sleep pattern even after only a few doses.展开更多
文摘据英国《BBc新闻》（BBCNEWS）2016-07-23报道，美国休斯顿大学（University of Houston）的一项研究发现，睡眠不足对儿童影响也是深远的，会令儿童成年后更易罹患抑郁症和焦虑症。休斯顿睡眠及焦虑研究中心（Sleep and Anxiety Center of Houston, SACH）的研究人员为了研究儿童睡眠对认知、行为及心理的影响，对50名7—11岁儿童进行暂时限制性睡眠实验。
基金Supported by Grant 50633 from CONACyT to Jiménez-Anguiano A
文摘AIM： To analyze the polygraphic sleep patterns during cirrhosis progression in a rat model by repeated CCh administration. METHODS： Male Wistar rats received three weekly injections of CCl4 for 11 wk, and were analyzed before and during the induction of cirrhosis. Rats were im- planted with electrodes to record their sleep patterns. Polygraph recordings were made weekly over 11 wk for 8 h, during the light period. After a basal recording, rats received three weekly injections of CCl4. Histological confirmation of cirrhosis was performed after 11 wk. RESULTS： The results showed a progressive decrease in total wake time that reached statistical significance from the second week of treatment. In addition, there was an increase in total time of slow wave sleep （SWS）Ⅱ and rapid eye movement sleep （REM sleep） in most of the 11 wk. SWS I showed no significant variations. During the final weeks, a significant increase in REM sleep frequency was also observed. Histological analyses of the livers showed unequivocal signs of cirrhosis. CONCLUSION： These data suggest that hepatic failure produced by CCh administration is capable of modifying the sleep pattern even after only a few doses.
