本文通过两组含磷非对映异构体^(31)p NMR化学位移的测定和分子力学计算,观察到非对映异构体之间,分子力学计算的磷原子局部Van der Waals相互作用能(E_(VDW-P))是影响其^(31)p NMR化学位移的主要因素,即E_(VDW-P)大的异构体,δ_(31P)...本文通过两组含磷非对映异构体^(31)p NMR化学位移的测定和分子力学计算,观察到非对映异构体之间,分子力学计算的磷原子局部Van der Waals相互作用能(E_(VDW-P))是影响其^(31)p NMR化学位移的主要因素,即E_(VDW-P)大的异构体,δ_(31P)在低场;E_(VDW-P)小的,δ_(31P)在高场。这一结果对利用非对映异构体中某核的NMR化学位移的实验测定,结合分子力学计算的该核的局部Van der Waals相互作用能。建立一种简便的确定非对映异构体中未知不对称中心的绝对构型的新方法,具有一定的理论意义和实用价值。展开更多
Cell death manner is related to the contents of intra cell energy substances. The rate constants and the half life time of ATP, phosphocreatine (PCr) and inorganic phosphorus (P i) in different cells of eel and crucia...Cell death manner is related to the contents of intra cell energy substances. The rate constants and the half life time of ATP, phosphocreatine (PCr) and inorganic phosphorus (P i) in different cells of eel and crucian during their death have been determined with 31 P NMR. It has been found that there are differences in rate constants and change rule of these energy substances for different animals and different cells in the same animal from this study. The decreasing order of the half life time is: muscle of eel>brain of eel>muscle of crucian for ATP; brain of eel≈muscle of eel>muscle of crucian for PCr. These results are very vital to understanding the concerned change pattern of energy substances and the speed of cell death.展开更多
文摘本文通过两组含磷非对映异构体^(31)p NMR化学位移的测定和分子力学计算,观察到非对映异构体之间,分子力学计算的磷原子局部Van der Waals相互作用能(E_(VDW-P))是影响其^(31)p NMR化学位移的主要因素,即E_(VDW-P)大的异构体,δ_(31P)在低场;E_(VDW-P)小的,δ_(31P)在高场。这一结果对利用非对映异构体中某核的NMR化学位移的实验测定,结合分子力学计算的该核的局部Van der Waals相互作用能。建立一种简便的确定非对映异构体中未知不对称中心的绝对构型的新方法,具有一定的理论意义和实用价值。
文摘Cell death manner is related to the contents of intra cell energy substances. The rate constants and the half life time of ATP, phosphocreatine (PCr) and inorganic phosphorus (P i) in different cells of eel and crucian during their death have been determined with 31 P NMR. It has been found that there are differences in rate constants and change rule of these energy substances for different animals and different cells in the same animal from this study. The decreasing order of the half life time is: muscle of eel>brain of eel>muscle of crucian for ATP; brain of eel≈muscle of eel>muscle of crucian for PCr. These results are very vital to understanding the concerned change pattern of energy substances and the speed of cell death.
