＂Qi＂ （spirit） is originally an ancient Chinese philosophical term regarded as the fundamental material to constitute the universe. Later, it＇s used as a term in literary criticism referring to the authors＇ talen...＂Qi＂ （spirit） is originally an ancient Chinese philosophical term regarded as the fundamental material to constitute the universe. Later, it＇s used as a term in literary criticism referring to the authors＇ talent, qualities, and their work styles. Poetry, as a language form concentrating thoughts and feelings, is the best form reflecting the various changes of＂Qi＂ （spirit）. ＂Qi＂ （spirit） combines the style, imagery and charm of a poem in a union, translation of the poem should be close to such a combination. Translation of＂Qi＂ （spirit） is a pursuit of translating poetry which is based on translation of sense and image, but it may focus more on the wording technique with a wide insight on the original poem including the meaning and the tone of the poem and the author＇s thoughts and feelings, focusing on an overall effect of appreciation.展开更多
Using the technique of smooth filtering and cylindrical filtering,the initial vortex circulation and large-scale environmental field were separated from the background field.Then the separated initial vortex circulati...Using the technique of smooth filtering and cylindrical filtering,the initial vortex circulation and large-scale environmental field were separated from the background field.Then the separated initial vortex circulation was translated and reinserted in the location where it was observed.This led to the determination of a method of initial vortex relocation.For seven tropical cyclones at 23 points of measurement time in the years of 2006 and 2007,two schemes,either directly adding a tropical cyclone bogus model in the background or adding it after the relocation of the initial vortex in the background field,were employed.Simulation experiments were compared.The results showed that the mean errors of the simulated tropical cyclone tracks at 24 and 48 hours were both smaller with the scheme of adding tropical cyclone bogus model after the relocation of the initial vortex in the background field.The relocation method of the initial vortex decreases the error caused by the deviation of the initial tropical cyclone location in tropical cyclone models.The relocation method is conducive to improving the track forecast of tropical cyclone models and has a good perspective for operational application.展开更多
Cells encountering hypoxic stress conserve resources and energy by downregulating the protein synthesis. Here we demonstrate that one mechanism in this response is the translational repression of TOP mRNAs that encode...Cells encountering hypoxic stress conserve resources and energy by downregulating the protein synthesis. Here we demonstrate that one mechanism in this response is the translational repression of TOP mRNAs that encode components of the translational apparatus. This mode of regulation involves TSC and Rheb, as knockout of TSC1 or TSC2 or overexpression of Rheb rescued TOP mRNA translation in oxygen-deprived celts. Stress-induced translational repression of these mRNAs closely correlates with the hypophosphorylated state of 4E-BP, a translational repressor. However, a series of 4E-BP loss- and gain-of-function experiments disprove a cause-and- effect relationship between the phosphorylation status of 4E-BP and the translational repression of TOP mRNAs under oxygen or growth factor deprivation. Furthermore, the repressive effect of anoxia is similar to that attained by the very efficient inhibition of mTOR activity by Torin 1, but much more pronounced than roptor or rictor knockouL Likewise, deficiency of raptor or rictor, even though it mildly downregulated basal translation efficiency of TOP mRNAs, failed to suppress the oxygen-mediated translational activation of TOP mRNAs. Finally, co-knockdown of TIA-1 and TIAR, two RNA-binding proteins previously implicated in translational repression of TOP mRNAs in amino acid-starved cells, failed to relieve TOP mRNA translation under other stress conditions. Thus, the nature of the proximal translational regulator of TOP m RNAs remains elusive.展开更多
文摘＂Qi＂ （spirit） is originally an ancient Chinese philosophical term regarded as the fundamental material to constitute the universe. Later, it＇s used as a term in literary criticism referring to the authors＇ talent, qualities, and their work styles. Poetry, as a language form concentrating thoughts and feelings, is the best form reflecting the various changes of＂Qi＂ （spirit）. ＂Qi＂ （spirit） combines the style, imagery and charm of a poem in a union, translation of the poem should be close to such a combination. Translation of＂Qi＂ （spirit） is a pursuit of translating poetry which is based on translation of sense and image, but it may focus more on the wording technique with a wide insight on the original poem including the meaning and the tone of the poem and the author＇s thoughts and feelings, focusing on an overall effect of appreciation.
基金Natural Science Foundation of China (9101501190715031+2 种基金40875026)Team Project of Foundation of Natural Science of Guangdong Province(8351030101000002)Project of Science and Technology of Guangdong Province(2008B030303025)
文摘Using the technique of smooth filtering and cylindrical filtering,the initial vortex circulation and large-scale environmental field were separated from the background field.Then the separated initial vortex circulation was translated and reinserted in the location where it was observed.This led to the determination of a method of initial vortex relocation.For seven tropical cyclones at 23 points of measurement time in the years of 2006 and 2007,two schemes,either directly adding a tropical cyclone bogus model in the background or adding it after the relocation of the initial vortex in the background field,were employed.Simulation experiments were compared.The results showed that the mean errors of the simulated tropical cyclone tracks at 24 and 48 hours were both smaller with the scheme of adding tropical cyclone bogus model after the relocation of the initial vortex in the background field.The relocation method of the initial vortex decreases the error caused by the deviation of the initial tropical cyclone location in tropical cyclone models.The relocation method is conducive to improving the track forecast of tropical cyclone models and has a good perspective for operational application.
文摘Cells encountering hypoxic stress conserve resources and energy by downregulating the protein synthesis. Here we demonstrate that one mechanism in this response is the translational repression of TOP mRNAs that encode components of the translational apparatus. This mode of regulation involves TSC and Rheb, as knockout of TSC1 or TSC2 or overexpression of Rheb rescued TOP mRNA translation in oxygen-deprived celts. Stress-induced translational repression of these mRNAs closely correlates with the hypophosphorylated state of 4E-BP, a translational repressor. However, a series of 4E-BP loss- and gain-of-function experiments disprove a cause-and- effect relationship between the phosphorylation status of 4E-BP and the translational repression of TOP mRNAs under oxygen or growth factor deprivation. Furthermore, the repressive effect of anoxia is similar to that attained by the very efficient inhibition of mTOR activity by Torin 1, but much more pronounced than roptor or rictor knockouL Likewise, deficiency of raptor or rictor, even though it mildly downregulated basal translation efficiency of TOP mRNAs, failed to suppress the oxygen-mediated translational activation of TOP mRNAs. Finally, co-knockdown of TIA-1 and TIAR, two RNA-binding proteins previously implicated in translational repression of TOP mRNAs in amino acid-starved cells, failed to relieve TOP mRNA translation under other stress conditions. Thus, the nature of the proximal translational regulator of TOP m RNAs remains elusive.
