Reproducibility of optical quality parameters measured at objective and subjective best focuses in a doublepass system

AIMTo evaluate intra-session repeatability and reproducibility of optical quality parameters measured at objective and subjective best focuses in a double-pass system.METHODSThirty Chinese healthy adults (19 to 40 years old) meeting our inclusion criterion were enrolled in the study. After a basic eye examination, two methods of optical quality measurement, based on subjective and objective best focuses were performed using the Optical Quality Analysis System (OQAS) with an artificial pupil diameter of 4.0 mm.RESULTSWith each method, three consecutive measurements of the following parameters: the modulation transfer function cutoff frequency (MTFcutoff), the Strehl2D ratio, the OQAS values (OVs) at contrasts of 100%, 20%, 9% and the objective scatter index (OSI) were performed by an experienced examiner. The repeatability of each method was evaluated by the repeatability limit (RL) and the coefficient of repeatability (COR). Reproducibility of the two methods was evaluated by intra-class correlation coefficient (ICC) and the 95% limits of agreement (Bland and Altman analysis). Thirty subjects, seven females and twenty three males, of whom 15 right eyes and 15 left eyes were selected randomly for recruitment in the study. The RLs (percentage) for the six parameters measured at objective focus and subjective focus ranged from 8.44% to 15.13% and 10.85% to 16.26%, respectively. The CORs for the two measurement methods ranged from 8.27% to 14.83% and 10.63% to 15.93%, respectively. With regard to reproducibility, the ICCs for the six parameters of OQAS ranged from 0.024 to 0.276. The 95% limits of agreement obtained for the six parameters (in comparison of the two methods) ranged from -0.57 to 42.18 (MTFcutoff), -0.01 to 0.23 (Strehl2D ratio), -0.02 to 1.40 (OV100%), -0.10 to 1.75 (OV20%), -0.14 to 1.80 (OV9%) and -1.46 to 0.18 (OSI).CONCLUSIONMeasurements provided by OQAS with either method showed a good repeatability. However, the results obtained from the two different measurement methods showed a poor reproducibility. These findings suggest that it might be best to evaluate patients' optical quality by OQAS using the best focus as chosen automatically by the instrument.

FOCUS-PDCA在降低在新生儿院内尿布性皮炎发生率的应用研究

探讨FOCUS -PDCA在新生儿院内尿布性皮炎管理的应用效果。方法 选取2023年6月1日至2023年9月30日入住新生儿患儿 379例,按入院时间先后顺序分为对照组(2023年6月1号-2023年7月31号)和试验组(2023年8月1号-2023年9月31号)。对照组采取常规护理方案,试验组采取运用FOCUS -PDCA进行修订相关流程、护理常规、开展针对性培训、加强督查与干预等循环管理。比较2组新生儿院内尿布性皮炎发生率。结果 试验组院内尿布性皮炎发生率为9.2‰,低于对照组的25.2 ‰(χ2=4.410578,P<0.05);且2023年8月、9月新生儿院内尿布性皮炎的发生率分别为15.8‰、11.8‰,整体呈一个下降的趋势。结论 采用FOCUS -PDCA进行循环管理,实施培训、督查与干预用于新生儿住院患者管理,可降低其院内尿布性皮炎的发生率。

＂Three Rare Mineral Resources＂ and Crystalline Graphite Have Become Prospecting Focuses in China

With the global rise of industries of the new-generation information technology, energy conservation and environmental protection, biotechnology, high-end manufacturing, new materials and clean-energy vehicles, traditional metal materials cannot meet the functional requirements. Consequently, ＂three rare mineral resources＂, regarded as the best altemative for current and future new industries, have received much attention among industrial circles and have become a new focus during the present geological prospecting in China.

Study on Technologies for Information Monitoring and Quick Response of Agricultural Focuses and Significant Events

This article analyzed the importance of information monitoring and quick response on agricultural focuses and significant events, proposed the workflow and technical framework for information monitoring and quick response based on modern information technologies, and explained key technologies during implementation and the functional structure for prototype system of the technical support platform.

Co-word clustering analysis for nursing safety management research focuses by PubMed

Objective： To analyze hot research areas and the present research status of nursing safety management in PubMed. Methods： PubMed was searched using ＂safety management＂ for the literature on nursing safety management. BICOMB 2.0 and SPSS 20.0 software were used to analyze high-frequency keywords and conduct co-word clustering analysis. Results： We searched for totally 2353 articles related to our topic and extracted 19 high-frequency keywords （27.50%）. Five research focuses were concluded, including： study on nursing safety culture; team work to promote nursing safety; practice of nursing safety management; workplace violence against nursing staffs; nursing safety and quality evaluation standard. Conclusion： Analysis of the hotspots of nursing safety management in the past 10 years will contribute to understanding the research emphases and trend of development, and provide reference for the study and practice of nursing safety management.

Properties of focused Laguerre–Gaussian beam propagating in anisotropic ocean turbulence

We analyze the properties of a focused Laguerre–Gaussian(LG)beam propagating through anisotropic ocean turbulence based on the Huygens–Fresnel principle.Under the Rytov approximation theory,we derive the analytical formula of the channel capacity of the focused LG beam in the anisotropic ocean turbulence,and analyze the relationship between the capacity and the light source parameters as well as the turbulent ocean parameters.It is found that the focusing mirror can greatly enhance the channel capacity of the system at the geometric focal plane in oceanic turbulence.The results also demonstrate that the communication link can obtain high channel capacity by adopting longer beam wavelength,greater initial beam waist radius,and larger number of transmission channels.Further,the capacity of the system increases with the decrease of the mean squared temperature dissipation rate,temperature-salinity contribution ratio and turbulence outer scale factor,and with the increase of the kinetic energy dissipation rate per unit mass of fluid,turbulence inner scale factor and anisotropy factor.Compared to a Hankel–Bessel beam with diffraction-free characteristics and unfocused LG beam,the focused LG beam shows superior anti-turbulence interference properties,which provide a theoretical reference for research and development of underwater optical communication links using focused LG beams.

Topic Focuses of APEC Meeting2014

On November 5-11,China hosted the 2014 APEC Economic Leaders’Week in Beijing.China’s Foreign Trade invited three experts focusing on APEC issues to share their thoughts on this year’s APEC meeting.1 What do you think of the meaning and impact of China’s holding APEC meeting this year?2 As we know,this theme of the summit is"Shaping the future through Asia-Pacific Partnership".There are three important issues of

Co-doped BaFe_(2)As_(2) Josephson junction fabricated with a focused helium ion beam

Josephson junction plays a key role not only in studying the basic physics of unconventional iron-based superconductors but also in realizing practical application of thin-film based devices,therefore the preparation of high-quality iron pnictide Josephson junctions is of great importance.In this work,we have successfully fabricated Josephson junctions from Co-doped BaFe_(2)As_(2)thin films using a direct junction fabrication technique which utilizes high energy focused helium ion beam(FHIB).The electrical transport properties were investigated for junctions fabricated with various He^(+)irradiation doses.The junctions show sharp superconducting transition around 24 K with a narrow transition width of 2.5 K,and a dose correlated foot-structure resistance which corresponds to the effective tuning of junction properties by He^(+)irradiation.Significant J_c suppression by more than two orders of magnitude can be achieved by increasing the He^(+)irradiation dose,which is advantageous for the realization of low noise ion pnictide thin film devices.Clear Shapiro steps are observed under 10 GHz microwave irradiation.The above results demonstrate the successful fabrication of high quality and controllable Co-doped BaFe_(2)As_(2)Josephson junction with high reproducibility using the FHIB technique,laying the foundation for future investigating the mechanism of iron-based superconductors,and also the further implementation in various superconducting electronic devices.

参仙升脉口服液化学成分的UHPLC-Q Exactive Focus MS/MS快速分析

目的探究参仙升脉口服液的化学物质基础。方法利用超高效液相色谱-四极杆/静电场轨道阱高分辨质谱(UHPLC-Q Exactive Focus MS/MS)对参仙升脉口服液的化学成分进行整体、系统辨识。采用Thermo Accucore aQ C_(18)色谱柱(150 mm×2.1 mm,2.6μm),流动相0.1%甲酸水溶液(A)-甲醇(B)梯度洗脱,洗脱程序为0-13 min,5%-60%B;13-27 min,60%-95%B;27-30 min,95%B,流速0.3 mL·min^(-1),柱温30°C;质谱分析离子化方式为加热电喷雾离子化(H-ESI),扫描模式为正、负离子切换,扫描范围m/z 120-1800,碰撞能量30 eV、50 eV、70 eV。结果共鉴定出160个化学成分,包括29个黄酮类成分,24个有机酸类成分,21个生物碱类成分,19个萜类成分,15个苯丙素类成分,12个皂苷类成分和40个其他类成分;其中6个化学成分(芦丁、补骨脂苷、异补骨脂苷、补骨脂素、异补骨脂素和补骨脂酚)经对照品比对确认。结论该研究借助UHPLC-Q Exactive Focus MS/MS技术实现了参仙升脉口服液化学成分准确、快速、系统的分析和鉴定,为其化学物质基础的阐明和质量控制提供了重要依据。

Focusing on the tetra-partite synapse in Parkinson’s disease research using human patient-derived neurons

Parkinson’s disease(PD)was first described as a neurological disease by Dr.James Parkinson in 1817 as a“shaking palsy”.Since that time,much more is known about the pathophysiology of PD yet the disease is still uncurable.The hallmark of the disease is often considered Lewy body neural inclusions in the substantia nigra pars compacta and other brain areas,although not all patients have these inclusions.The patients exhibit massive neuronal cell loss in the substantia nigra pars compacta,which is associated with the motor symptoms of tremor,bradykinesia,rigidity,and postural instability.PD is the second most common neurodegenerative disease after Alzheimer’s disease with a prevalence of around 1%of individuals over the age of 60.

FOCUS-PDCA模式对老年肌少症病人日常生活能力和生活质量影响的Meta分析

目的:系统评价FOCUS-PDCA模式对老年肌少症病人日常生活能力和生活质量的影响。方法:检索PubMed、Web of Science、the Cochrane Library、中国知网、万方数据库、维普数据库、中国生物医学文献数据库中关于FOCUS-PDCA模式对老年肌少症病人日常生活能力和生活质量影响的随机对照试验,检索时限从建库至2022年12月31日。采用RevMan 5.4软件进行Meta分析。结果:共纳入5篇文献,涉及534例病人。Meta分析结果显示,使用FOCUS-PDCA模式干预可有效改善病人的生活质量[SMD=2.52,95%CI(1.50,3.54),P<0.000 01],提高日常活动能力[MD=23.94,95%CI(14.96,32.96),P<0.000 01]。结论:现有证据表明,FOCUS-PDCA模式可提高老年肌少症病人的日常生活能力,改善其生活质量。

Shandong focuses on a clean energy future

According to Shandong Development and Reform Commission, the province’s new energy industry is expected to grow at an annual average rate of 20% to reach

Focus on pet diseases

Pets become vital companions in human life.Tey ofer companionship and emotional support,and contribute signifcantly to physical and mental health,as well as social activities.Living with pets can stimulate human bodies to release more“afnity hormones”such as serotonin,dopamine,and oxytocin,which helps alleviate negative emotions.Te human-animal bond can enhance the human body’s ability to eliminate toxins,reduce the risk of illnesses,strengthen the immune system,and alleviate depressive symptoms.Moreover,pet-related social activities can facilitate the making of new friends and the establishment of social connections,serving as a bridge for those who struggle with social interactions.

Simulating the evolution of focused waves by a two-layer Boussinesq-type model

Accurate simulation of the evolution of freak waves by the wave phase focusing method requires accurate linear and nonlinear properties,especially in deep-water conditions.In this paper,we analyze the ability to simulate deep-water focused waves of a two-layer Boussinesq-type(BT)model,which has been shown to have excellent linear and nonlinear performance.To further improve the numerical accuracy and stability,the internal wavegenerated method is introduced into the two-layer Boussinesq-type model.Firstly,the sensitivity of the numerical results to the grid resolution is analyzed to verify the convergence of the model;secondly,the focused wave propagating in two opposite directions is simulated to prove the symmetry of the numerical results and the feasibility of the internal wave-generated method;thirdly,the limiting focused wave condition is simulated to compare and analyze the wave surface and the horizontal velocity of the profile at the focusing position,which is in good agreement with the measured values.Meanwhile the simulation of focused waves in very deep waters agrees well with the measured values,which further demonstrates the capability of the two-layer BT model in simulating focused waves in deep waters.

A Study on the Focuses and Fronts of International Second Language Acquisition Researches -Statistical Analysis of the Articles Published in Language Learning(2012-2016)

Keywords word frequency and co-word analysis are adopted in an attempt to to investigate the focuses and fronts of inter-national second language acquisition(SLA) researches by analyzing the key words in articles published in the internationally re-nowned SLA academic journal Language Learning from 2012 to 2016. It is found that the best researched topics in SLA are vocabu-lary acquisition, explicit knowledge, form-focused teaching, language use, and so on, among which learner's language attracts themost attention. In terms of research methods, they become more diversified and interdisciplinary, as empirical studies take a domi-nant position and experiments still play a leading role, displaying an interdisciplinary feature.

Italian Textile Machinery Industry Focuses on Sustainability

As for fashion industry,Italian brands always play as one of the leaders influencing the global trends.This time,in Shanghai,the Italian textile machinery manufacturers highlight the latest proposals on sustainability and eco-friendly technology.

Half-integer Shapiro steps in MgB_(2) focused He ion beam Josephson junctions

Half-integer microwave induced steps(Shapiro steps)have been observed in many different Josephson junction systems,which have attracted a lot of attention because they signify the deviation of current phase relation(CPR)and uncover many unconventional physical properties.In this article,we first report the discovery of half-integer Shapiro steps in MgB_(2)focused He ion beam(He-FIB)Josephson junctions.The half-integer steps'dependence on microwave frequency,temperature,microwave power,and magnetic field is also analyzed.We find that the existence of half-integer steps can be controlled by the magnetic field periodically,which is similar to that of high temperature superconductor(HTS)grain boundary junctions,and the similarity of the microstructures between gain boundary junctions and He-FIB junctions is discussed.As a consequence,we mainly attribute the physical origin of half-integer steps in MgB_(2)He-FIB junctions to the model that a He-FIB junction is analogous to a parallel junctions'array.Our results show that He-FIB technology is a promising platform for researching CPR in junctions made of different superconductors.

China’s Unprecedented Focus on Foreign Investment

The Communique of the Third Plenary Session of the 20th Central Committee of the Communist Party of China(CPC),which has just been concluded,mentions that it is necessary to steadily expand institutional opening-up,deepen foreign trade structural reform,further reform the management systems for inward and outward investment,improve planning for regional opening up,and refine the mechanisms for high-quality cooperation under the Belt and Road Initiative.