Aim: To describe the two-dimensional elastographic profile according to the Shearwave (2D-SWE) technique in patients with chronic liver disease in Lom. Materials and method: Cross-sectional, descriptive study conducte...Aim: To describe the two-dimensional elastographic profile according to the Shearwave (2D-SWE) technique in patients with chronic liver disease in Lom. Materials and method: Cross-sectional, descriptive study conducted over seven month at the Autel dElie Clinic in Lom, from January to August 2022, on adult patients with chronic liver disease who underwent abdominal ultrasound coupled with two-dimensional elastography. Results: The sample size was 54 patients. The mean age of the patients was 33 12 years, with extremes of 18 and 66 years. Patients aged 30 years or less accounted for 48.1% (n = 26). All patients (n = 54) had at least one transaminase assay with a mean of 69.3 78.3 IU/l (AST) and 59.3 82.8 IU/l (ALT). There was no statistically significant association between the biological parameters and the presence of fibrosis. Viral liver disease was the main cause, accounting for 81.5% (n = 44) of cases, with no significant association with the degree of fibrosis. Ultrasound revealed a dysmorphic liver (57.4%;n = 31) and portal hypertension (18.5%, n = 10). Fibrosis stages F1, F2 and F4 accounted for (48.1%, n = 26), (24.1%, n = 13) and (13%, n = 7) of cases respectively. Liver dysmorphia was significantly associated with the presence of fibrosis (p = 0.012) and portal hypertension was significantly associated with the degree of fibrosis (p = 0.0063). Conclusion: Assessment of liver fibrosis in patients with chronic liver disease using 2D-SWE elastography is essential for patient follow-up.展开更多
【目的】将声触诊弹性成像(STE)和二维剪切波弹性成像(2D-SWE)检测肝脏硬度进行比较,为STE新技术的临床应用提供循证依据。【方法】采用STE和2D-SWE技术,对43例健康志愿者和63例肝硬化患者行肝硬度检测,对比分析两种技术的检测成功率、...【目的】将声触诊弹性成像(STE)和二维剪切波弹性成像(2D-SWE)检测肝脏硬度进行比较,为STE新技术的临床应用提供循证依据。【方法】采用STE和2D-SWE技术,对43例健康志愿者和63例肝硬化患者行肝硬度检测,对比分析两种技术的检测成功率、操作者内重复性、测值相关性和测值差异。【结果】肝脏STE、2D-SWE检测成功率分别为100%(106/106)、96.2%(102/106)(χ^2=2.320,P=0.128),4例2D-SWE检测失败的均为肝硬化患者。在健康组STE测值高于2D-SWE[5.83(5.30~6.37)kPa vs 5.00(4.80~5.20)kPa,Z=4.419,P<0.001]、肝硬化组低于2D-SWE[15.82(11.71~25.02)kPa vs 18.50(11.95~29.93)kPa,Z=-2.981,P=0.003]。STE和2D-SWE两种技术的测值相关系数为0.896(95%CI:0.849~0.928,P<0.001)。【结论】STE检测成功率高、重复性好,尤其在肝硬化患者穿透性好、与2D-SWE比较更具优势;STE测值与2D-SWE不直接等同,临床应用中需要注意。展开更多
文摘Aim: To describe the two-dimensional elastographic profile according to the Shearwave (2D-SWE) technique in patients with chronic liver disease in Lom. Materials and method: Cross-sectional, descriptive study conducted over seven month at the Autel dElie Clinic in Lom, from January to August 2022, on adult patients with chronic liver disease who underwent abdominal ultrasound coupled with two-dimensional elastography. Results: The sample size was 54 patients. The mean age of the patients was 33 12 years, with extremes of 18 and 66 years. Patients aged 30 years or less accounted for 48.1% (n = 26). All patients (n = 54) had at least one transaminase assay with a mean of 69.3 78.3 IU/l (AST) and 59.3 82.8 IU/l (ALT). There was no statistically significant association between the biological parameters and the presence of fibrosis. Viral liver disease was the main cause, accounting for 81.5% (n = 44) of cases, with no significant association with the degree of fibrosis. Ultrasound revealed a dysmorphic liver (57.4%;n = 31) and portal hypertension (18.5%, n = 10). Fibrosis stages F1, F2 and F4 accounted for (48.1%, n = 26), (24.1%, n = 13) and (13%, n = 7) of cases respectively. Liver dysmorphia was significantly associated with the presence of fibrosis (p = 0.012) and portal hypertension was significantly associated with the degree of fibrosis (p = 0.0063). Conclusion: Assessment of liver fibrosis in patients with chronic liver disease using 2D-SWE elastography is essential for patient follow-up.
文摘【目的】将声触诊弹性成像(STE)和二维剪切波弹性成像(2D-SWE)检测肝脏硬度进行比较,为STE新技术的临床应用提供循证依据。【方法】采用STE和2D-SWE技术,对43例健康志愿者和63例肝硬化患者行肝硬度检测,对比分析两种技术的检测成功率、操作者内重复性、测值相关性和测值差异。【结果】肝脏STE、2D-SWE检测成功率分别为100%(106/106)、96.2%(102/106)(χ^2=2.320,P=0.128),4例2D-SWE检测失败的均为肝硬化患者。在健康组STE测值高于2D-SWE[5.83(5.30~6.37)kPa vs 5.00(4.80~5.20)kPa,Z=4.419,P<0.001]、肝硬化组低于2D-SWE[15.82(11.71~25.02)kPa vs 18.50(11.95~29.93)kPa,Z=-2.981,P=0.003]。STE和2D-SWE两种技术的测值相关系数为0.896(95%CI:0.849~0.928,P<0.001)。【结论】STE检测成功率高、重复性好,尤其在肝硬化患者穿透性好、与2D-SWE比较更具优势;STE测值与2D-SWE不直接等同,临床应用中需要注意。
