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Association between Ambient Air Pollution and Outpatient Visits for Acute Bronchitis in a Chinese City 被引量:13
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作者 GUO Li Juan ZHAO Ang +2 位作者 CHEN Ren Jie KAN Hai Dong KUANG Xing Ya 《Biomedical and Environmental Sciences》 SCIE CAS CSCD 2014年第11期833-840,共8页
Objective To investigate the short-term association between outdoor air pollution and outpatient visits for acute bronchitis,which is a rare subject of research in the mainland of China.Methods A time-series analysis ... Objective To investigate the short-term association between outdoor air pollution and outpatient visits for acute bronchitis,which is a rare subject of research in the mainland of China.Methods A time-series analysis was conducted to examine the association of outdoor air pollutants with hospital outpatient visits in Shanghai by using two-year daily data(2010-2011).Results Outdoor air pollution was found to be associated with an increased risk of outpatient visits for acute bronchitis in Shanghai.The effect estimates of air pollutants varied with the lag structures of the concentrations of the pollutants.For lag06,a 10 μg/m3 increase in the concentrations of PM10,SO2,and NO2 corresponded to 0.94%(95% CI:0.83%,1.05%),11.12%(95% CI:10.76%,11.48%),and 4.84%(95% CI:4.49%,5.18%) increases in hospital visits for acute bronchitis,respectively.These associations appeared to be stronger in females(P〈0.05).Between-age differences were significant for SO2(P〈0.05),and between-season differences were also significant for SO2(P〈0.05).Conclusion Our analyses have provided the first evidence that the current air pollution level in China has an effect on acute bronchitis and that the rationale for further limiting air pollution levels in Shanghai should be strengthened. 展开更多
关键词 Air pollution Outpatient visits acute bronchitis Time-series
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Study on the underlying mechanism of almond and platycodon in treating acute bronchitis based on network pharmacology 被引量:1
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作者 Shen-Yan Cai Jia-Yong Shi Tian-Jiong Luo 《Journal of Hainan Medical University》 2021年第4期51-57,共7页
Objective:Network pharmacology method was adopted in this study to screen the target of almond and platycodon of the treatment to Acute Bronchitis and exploring its mechanism of treatment.Methods:Chemical components a... Objective:Network pharmacology method was adopted in this study to screen the target of almond and platycodon of the treatment to Acute Bronchitis and exploring its mechanism of treatment.Methods:Chemical components and selected targets related to almond and platycodon were searched through the Traditional Chinese Medicine Systems Pharmacology Database and Analysis Platform(TCMSP).Through GeneCards database,OMIM database,disease targets of Acute Bronchitis were searched.Venn diagram analysis was used to screen the common targets between drugs and disease,and then the interaction network diagram of the targets was constructed by String.Cytoscape3.7.0 was applied to construct the drugcomposition-target-disease interacted network.GO Enrichment and KEGG Enrichment Analysis of Targets were based on DAVID.Results:There are 25 active components such as luteolin,acacetin and Glabridin in the almond and platycodon,corresponding to 127 targets.81 targets are obtained by mapping with 1593 targets of acute bronchitis,including PTGS2,PTGS1,AKT1,TP53,etc.KEGG enrichment analysis mainly involves Apoptosis,PI3K-Akt signaling pathway,TNF signaling pathway,T cell receptor signaling pathway,etc.Conclusion:Based on the network pharmacology,the potential mechanism of almond and platycodon in the treatment of acute bronchitis was discussed,which provides ideas and directions for further experimental research. 展开更多
关键词 Network pharmacology ALMOND Platycodon acute bronchitis MECHANISM
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CLINICAL OBSERVATION ON TREATMENT OF ACUTE BRONCHITIS PRIMARILY WITH PRICKING-CUPPING ON BACK-SHU POINTS
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作者 徐蔚东 张永娟 +2 位作者 杨洁 陈晓香 刘永香 《World Journal of Acupuncture-Moxibustion》 2006年第2期15-18,共4页
To observe the clinical effect of treatment of acute bronchitis primarily with prickingcupping method on Back-shu points. Methods. The patients of acute bronchitis were randomly divided into 2 groups. In the observati... To observe the clinical effect of treatment of acute bronchitis primarily with prickingcupping method on Back-shu points. Methods. The patients of acute bronchitis were randomly divided into 2 groups. In the observation group, there were 36 cases, who were treated with the integrated traditional Chinese and western medicine, primarily the pricking-cupping method on Back-shu points; while in the control group, there were 29 cases who were given the conventinal treatment of western medicine. All the 2 groups were treated for 7 days as one treating course. Results: The total effective rate of the observation group was 97.2% while that of the control group was 82,8%, so there is a significant difference between them. On the first and third days the clinical manifestations were more satisfactorily improved in the treatment group than in the control group (P 〈 0.01) and on the fifth and seventh days, the comparison showed no significant difference (P〉0.05). Conclusion: The treatment of acute bronchitis by means of the integrated traditional Chinese and western medicine primarily with pricking-cupping method on Back-shu points is of marked therapeutic effect, simple manipulation, and little untoward effects, thus claiming the unique advantage. 展开更多
关键词 acute bronchitis Integrated traditional Chinese and western medicine Pricking-cupping method Back-shu point
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Short-term effects of air pollutants on hospital admissions for acute bronchitis in children:a multi-city time-series study in Southwest China 被引量:2
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作者 Yi He Wanyanhan Jiang +3 位作者 Jia-Qiang Liao Lin Jing Jia Li Lian Yang 《World Journal of Pediatrics》 SCIE CAS CSCD 2022年第6期426-434,共9页
Background Few studies have investigated the effects of air pollutants on children with acute bronchitis.This study aimed to explore the acute effects of four air pollutants[fine particulate matter(PM_(2.5)),inhalable... Background Few studies have investigated the effects of air pollutants on children with acute bronchitis.This study aimed to explore the acute effects of four air pollutants[fine particulate matter(PM_(2.5)),inhalable particulate matter(PM10),sulfur dioxide(SO_(2)),and nitrogen dioxide(NO_(2))]on the daily number of children admitted to the hospital for acute bronchitis in Sichuan Province,China.Methods The 49,975 records of hospitalized children with acute bronchitis from medical institutions in nine cities/prefectures,Sichuan Province,China,as well as the simultaneous meteorological data and air pollution data from 183 monitoring sites,were collected from 1 January 2017 to 31 December 2018.A generalized additive model was adopted to analyze the exposure–response and lag effects of hospitalizations of children with acute bronchitis to air pollutants.Stratified analyses were conducted based on sex,age,and season.Results The single-pollutant model showed that a 10µg/m3 increase at lag07 of PM_(2.5),PM10,SO_(2),and NO_(2) corresponded to an increase of 1.23%[95%confidence interval(CI)0.21–2.26%],1.33%(95%CI 0.62–2.05%),23.52%(95%CI 11.52–36.81%),and 12.47%(95%CI 8.46–16.64%)in daily hospitalizations for children with acute bronchitis,respectively.Children aged 0–2 were more prone to PM_(2.5)(P<0.05).Interestingly,the effects were stronger in the warm season than in transition seasons and the cool season for PM_(2.5) and PM10(P<0.05).Conclusion The higher daily average concentrations of four pollutants in Sichuan Province can result in an increased number of children hospitalized for acute bronchitis. 展开更多
关键词 acute bronchitis Air pollutants CHILDREN Time-series study
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Ambient Temperature and Outpatient Visits for Acute Exacerbation of Chronic Bronchitis in Shanghai: A Time Series Analysis 被引量:8
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作者 HUANG Fang ZHAO Ang +2 位作者 CHEN Ren Jie KAN Hai Dong KUANG Xing Ya 《Biomedical and Environmental Sciences》 SCIE CAS CSCD 2015年第1期76-79,共4页
The association between ambient temperature and acute exacerbation of chronic bronchitis (AECB) was still unknown. Therefore, we performed an epidemiological study in a large hospital of Shanghai to explore the rela... The association between ambient temperature and acute exacerbation of chronic bronchitis (AECB) was still unknown. Therefore, we performed an epidemiological study in a large hospital of Shanghai to explore the relationship about temperature and outpatient visit for AECB. We adopted a quasi-Poisson generalized additive models and distributed lag nonlinear models to estimate the accumulative effects of temperature on AECB across multiple days. We found significant non-linear effects of cold temperature on hospital visits for AECB, and the potential effect of cold temperature might last more than 2 weeks. The relative risks of extreme cold (first percentiles of temperature throughout the study period) and cold (10th percentile of temperature) temperature over lags 0-14 d were 2.98 [95% confidence intervals (CI): 1.77, 5.04] and 1.63 (95% Ch 1.21, 2.19), compared with the 25th percentile of temperature. However, we found no positive association between hospital visits and hot weather. This study showed that exposure to both extreme cold and cold temperatures were associated with increased outpatient visits for AECB in a large hospital of Shanghai. 展开更多
关键词 AECB Ambient Temperature and Outpatient Visits for acute Exacerbation of Chronic bronchitis in Shanghai
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Systematic review of Shufeng Jiedu capsules for acute attack of chronic bronchitis
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作者 Dan Dou Yuan-Ping Jia +3 位作者 Chuan-Hui Yao Yu-Juan Li Shu-Ying Lv Hong-Chun Zhang 《Journal of Hainan Medical University》 2022年第6期51-57,共7页
Objective:To systematically evaluate the efficacy and safety of Shufeng Jiedu Capsules in the treatment of acute attacks of chronic bronchitis.Methods:CNKI,VIP,CBM,WanFang,PubMed,EMbase,Cochrane Library and ChiCTR wer... Objective:To systematically evaluate the efficacy and safety of Shufeng Jiedu Capsules in the treatment of acute attacks of chronic bronchitis.Methods:CNKI,VIP,CBM,WanFang,PubMed,EMbase,Cochrane Library and ChiCTR were searched by computer,and randomized controlled trials of Shufeng Jiedu capsules in the treatment of AECB were integrated.The retrieval time was from the date of establishing the database to December 31,2020.Meta-analysis of outcome indicators[including effective rate,C-reactive protein(CRP),lung function[FEV1%and/or FEV1/FVC],interleukin-8(IL-8),tumor necrosis factor-α(TNF-α)]were carried out by RevMan 5.3 software,and the effective rate was tested by sequential analysis(TSA),and the quality of evidence was evaluated according to GRADE standards.Results:A total of 680 cases in 8 articles were included.Shufeng Jiedu Capsules improved the effective rate of clinicaltreatment[RR=1.20,95%CI(1.13,1.28)],improved lung function[FEV1:MD=0.33,95%CI(0.22,0.45),FEV1/FVC:MD=10.17,95%CI(8.15,12.19)],reduced CRP[MD=-7.32,95%CI(-8.42,-6.22)],IL-8[MD=-63.39,95%CI(-73.49,-53.29)],TNF-α[MD=-7.44,95%CI(-8.35,-6.53)]levels.The above differences were statistically significant(P<0.05),and no serious adverse reactions were reported in all studies.The results of TSA analysis showed that the experimental group had definite evidence for improving the efficiency.According to the GRADE evaluation system,the efficiency,TNF-αwere medium-quality evidences,FEV1 was low-quality evidence,and FEV1/FVC,CRP,and IL-8 were extremely low-quality evidence.Conclusions:The curative effect of Shufeng Jiedu capsule combined with western medicine in the treatment of AECB was better than that of single western medicine.Nevertheless,considering the limited sample size and the quality of included articles,higher quality RCTs are still needed to further confirm its effectiveness and safety. 展开更多
关键词 Shufeng Jiedu capsule acute attack of chronic bronchitis Meta analysis Sequential analysis
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TCM aerosol inhalation treatment in acute exacerbations of chronic bronchitis: a meta-analysis
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作者 Wei Luo Ji-Ni Yang +4 位作者 Yi-Hua Fan Ji-Fang Song Fang-Jing Liu Teng Zhang Qiang Zhang 《TMR Integrative Medicine》 2017年第1期9-19,共11页
Objectives: To determine whether traditional Chinese medicine (TCM) aerosol inhalation treatment is effective inthe treatment of acute exacerbation of chronic bronchitis. Methods: Search double-blind randomised cl... Objectives: To determine whether traditional Chinese medicine (TCM) aerosol inhalation treatment is effective inthe treatment of acute exacerbation of chronic bronchitis. Methods: Search double-blind randomised clinical trials(RCT) about the use of TCM aerosol inhalation in patient with acute exacerbation of chronic bronchitis via database including Chinese biomedicine literature database, Wanfang Data, CNKI, Pubmed, EMBASE and CochraneLibrary from the beginning to October 2016. Quality evaluation, data extraction and data analysis of these RCT wascarried out with reference to the Cochrane systematic review. Results: 16 studies with 738 patients in TCM aerosolinhalation group and 675 in control group were included. The results of meta-analysis showed, (1) TCM aerosolinhalation group could improve the total cure rate. (2) TCM aerosol inhalation could increase the expression of IL-2while decrease the expression of IL-8 and MDA in sputum and blood. (3) TCM aerosol inhalation could improvethe symptoms of cough, cough with sputum, cough with dyspnea and lung wet rales. It also improve the symptomsof cough, expectorate and lung wet rales. (4) Shorten the time of cough and lung rale. (5) The adverse reactionswere light only with 1 occurrence of nausea and vomiting. Conclusions: The use of TCM aerosol inhalation in thetreatment of acute exacerbation of chronic bronchitis was effective. However, the inclusion researches quality werenot very high, which only provided limited evidence for clinical application. Higher-quality randomized controlledtrials were needed for further study. 展开更多
关键词 Traditional Chinese medicine Aerosol inhalation acute exacerbation of chronic bronchitis META-ANALYSIS
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MANAGEMENT OF AE-CB/COPD: A SURVEY OF RESPIRATORY PHYSICIANS IN SOME REGIONS OF CHINA
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作者 程齐俭 邓伟吾 《Journal of Shanghai Second Medical University(Foreign Language Edition)》 2006年第1期48-50,70,共4页
Objective To investigate the bacteria spectrum isolated from AE-CB/ COPD and the manner of management of AE-CB/COPD in respiratory or internal medicine department in some regions of China. Methods Respiratory physicia... Objective To investigate the bacteria spectrum isolated from AE-CB/ COPD and the manner of management of AE-CB/COPD in respiratory or internal medicine department in some regions of China. Methods Respiratory physicians received questionnaire at randomization just after they managed a patient presenting to outpatient department with AE-CB/ COPD, on general conditions and symptoms of patients, type of examinations, diagnosis, type of antibiotics used and mode of administration. Results of sputum bacteria culture were followed up. Results Amang the1583 AE-CB/COPD, 63. 04% were male and 35.19% were female. 54.6% of them were older than 60 years. 81.87% of the patients produced sputum. Sputum bacteria culture, chest X-ray and chest CT were carried out to 21.3%, 66. 3% and 11. 1% patients, respectively. 355 strains were isolated from patients whose sputum bacteria culture was positive. Streptococcus pneumoniae, Haemophilus influenzae and Moraxella ca- tarrhalis were the three most isolates. 84. 7% of the 1583 AE-CB/COPD received 1692 times of antibiotic prescribing. The most frequently prescribed antibiotic were B-lactams (51.36% of all antibiotic prescribing), macrolides (14. 01% ) and quinolones (31.03%). Much more macrolides were prescribed in the area where mare patients pay the medicines at his own expense than those in the area where more patients share public health service. Conclusion In China, respiratory physicians can reasonably select antibiotics to manage acute exacerbation of chronic bronchitis/ chronic obstructive pulmonary disease in pulmonary outpatient department. Sputum culture is done in part of the patients, but susceptibility tests are missing. One issue revealed by the survey is that the list of prescribing medications laid down by government have great influence on antibiotic use. 展开更多
关键词 chronic bronchitis chronic obstructive pulmonary disease acute exacerbation management survey
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