Effect of wrist-ankle acupuncture on propofol dosage during painless colonoscopy:A randomized controlled prospective study

BACKGROUND The clinical advantages of painless colonoscopy can reduce the fear and discomfort of patients and increase the detection rate of diseases.Propofol has the characteristics of fast effect and short action time.It is a common choice for painless endoscopic sedation and anesthetics.However,propofol can cause severe respiratory and circulatory depression.Therefore,it is important to find a way to reduce the dose of propofol.AIM To explore the effect of wrist-ankle acupuncture on propofol dose during colonoscopy.METHODS Two hundred patients who were going to receive selective painless colonoscopy in Hebei Hospital of Traditional Chinese Medicine were selected and divided into wrist-ankle acupuncture group(WAA group,n=100)and control group(CON group,n=100).After entering the operation room,patients were given 0.025 mg/kg nabufine intravenously and propofol at the initial dose of 0.5 mg/kg.In patients who did not fall asleep,propofol(10 mg/time)was given until loss of consciousness.Prior to anesthesia,patients in WAA group were punctured by specialist in the inferior 1,2 and 3 regions according to the zoning principle of wrist-ankle acupuncture.The primary endpoint was required dose of propofol,and the secondary endpoints were the incidence of hypoxemia and hypotension.Furthermore,the following data were recorded:The operation time,wake-up time,incidence of nausea and vomiting,incidence of abdominal distention,post colonoscopy pain,examiners'satisfaction,patients'satisfaction and Borg fatigue index.This study has been registered in the Chinese Clinical Trial Registry(Registration Code:ChiCTR1900022177).RESULTS The induced dose of propofol and the total dose of propofol in WAA group were 80 mg and 110 mg,respectively,which were significantly lower than those in CON group(P<0.05).The incidences of hypoxemia and hypotension in the WAA group were 2.2%and 3.3%,respectively,significantly lower than those in the CON group(P<0.05).The incidence of abdominal distension in the WAA group was 8.8%,which was significantly lower than that in the CON group(P<0.05,28.9%).The waking time of WAA group was 3.26±0.87 min,which was significantly lower than that of CON group(6.06±0.88 min,P<0.05).CONCLUSION Wrist-ankle acupuncture can reduce the induction dose and total dose of propofol as well as the incidence of adverse reactions in painless colonoscopy without affecting the satisfaction of examiners and patients.This procedure is simple in operation and easy to promote in clinical practice.

ACUPUNCTURE TREATMENT FOR SPRAINS OF THE ANKLE JOINT IN 354 CASES

Sprains of the ankle joint is one of themost common soft tissue injuries,which isusually caused by a violent twisting.Thismovement can lacerate the interarticular lig-aments and the tendon insertions aroundthe ankle joint.We treated 354 cases of thistype of injury with acupuncture,yielding aninspiring therapeutic result.CLINICAL MATERIALSOf the 354 cases in this series,291 caseswere injured for the first time,and 63

CLINICAL OBSERVATION ON THE THERAPEUTIC EFFECTS OF WRIST-ANKLE ACUPUNCTURE IN TREATMENT OF PAIN OF VARIOUS ORIGINS

Wrist-ankle acupuncture is performed at the specific points of the wrist or ankle to treat diseases inyolving corresponding parts of the body. It is a new therapeutic method enlightened by the theory of channels and collaterals and the theory of nerves, and advanced through clinical trials. It, therefore, exhibits not only the advantages of traditional acupuncture, but also its unique characteristics, yielding satisfactory results especially in pain of various origins. A report is presented below.

11 CASES OF MOTOR INJURY OF ANTERIOR TALOFIBULAR LIGAMENT TREATED BY ACUPUNCTURE OF QIUXU(GB 40)-THROUGH-ZHAOHAI(KI 6)POINT

Injury of ankle is the most common in athletic injury.Because of anatomic particu- larity of ankle joint,i.e.lateral malleolus is long and thin and is located at the posterior and lower than medial malleolus.The medial malleolus is broad and flat and is located at the anterior.Lateral ligament is thinner and weaker than medial ligament and the muscle groups supporting strephexopodia is far inferi- or to the muscle groups supporting strephenopodia in strength,injury of ankle joint happens more at inversion sprain and in- jury of anterior talofibular ligament is induced often.Thus,rapid and effective treatment of anterior talofibular ligament injury can elevate better athletics of sportsman.Whenever the disease happened in students to exercise,the authors often used acupuncture of Qiuxu（GB 40）-through-Zhaohai（KI 6）point with strong stimulative manipulation,which could relieve more remakedly pain of the ankle joint caused by anterior talofibular ligament injury as re- ported in

隔姜灸与腕踝针治疗脊髓损伤后尿潴留的临床研究

目的探讨脊髓损伤(SCI)后神经源性膀胱尿潴留患者应用隔姜灸联合腕踝针治疗的效果。方法选择2022年1月至2023年12月驻马店市中医院收治的106例SCI后神经源性膀胱尿潴留患者,采用随机数字表分为两组。对照组53例患者实施常规康复治疗,研究组53例患者实施常规康复治疗+隔姜灸联合腕踝针治疗,比较两组排尿日记、尿动力学指标、膀胱功能、生活质量[泌尿症状困扰评分(USDS)]、抑郁情绪[焦虑自评量表(SAS)]。结果研究组患者治疗后最大尿流率(13.12±2.23)mL/s、最大排尿量(241.37±52.13)mL、膀胱最大容量(433.82±48.63)mL,高于对照组的(10.65±2.17)mL/s、(184.26±50.44)mL、(405.12±50.04)mL,充盈期膀胱压、平均排尿次数、尿失禁次数、膀胱残余尿量、膀胱功能评分、USDS、SAS评分低于对照组(P<0.05)。结论SCI后神经源性膀胱尿潴留患者应用隔姜灸联合腕踝针治疗可有效促进排尿,减轻尿潴留,其作用机制可能与改善膀胱功能有关,有助于改善患者生活质量。

Clinical efficacy of sticking-needle acupuncture plus tendon-regulating manipulation in the treatment of acute ankle sprain

Objective To explore the treatment effect of sticking-needle acupuncture plus tendon-regulating manipulation on pain,swelling and joint dysfunction due to acute ankle sprain.Methods A total of 80 patients with acute ankle sprain were recruited and divided into a control group and a treatment group according to the random number table method,with 40 patients in each group.Both groups received the same conventional interventions.The control group was treated with additional tendon-regulating manipulation,and the treatment group was treated with tendon-regulating manipulation plus sticking-needle acupuncture.The pain,swelling and joint dysfunction of the ankle were observed in both groups before and after 3 d,7 d and 14 d of treatment.Results Before treatment,there was no statistically significant difference in the visual analog scale(VAS)score of pain between the two groups(P>0.05).After treatment,the VAS scores of both groups showed a decreasing trend over time,and the differences within the groups were statistically significant(P<0.05).After 3 d,7 d and 14 d of treatment,the VAS scores in the treatment group were lower than those in the control group,with statistically significant differences(P<0.05).Before treatment,there was no statistically significant difference in the degree of swelling between the two groups(P>0.05).After treatment,the degrees of swelling in both groups showed a decreasing trend over time,and the differences within the groups were statistically significant(P<0.05).After 3 d and 7 d of treatment,the degrees of swelling in the treatment group were lower than those in the control group,with statistically significant differences(P<0.05).There was no statistical difference in the degree of swelling between the two groups after 14 d of treatment(P>0.05).Before treatment,there was no statistically significant difference in the American Orthopedic Foot Ankle Society(AOFAS)ankle-hindfoot scale score between the two groups(P>0.05).After treatment,the AOFAS ankle-hindfoot scale scores of both groups showed an increasing trend over time,and all the differences within the groups were statistically significant(P<0.05).After 3 d,7 d and 14 d of treatment,the AOFAS ankle-hindfoot scale scores in the treatment group were higher than those in the control group,with statistically significant differences(P<0.05).Conclusion Based on the routine intervention,the addition of sticking-needle acupuncture and tendon-regulating manipulation was better in alleviating pain and swelling and improving joint function in patients with acute ankle sprain than the addition of tendon-regulating manipulation alone.

Effect of wrist-ankle acupuncture on postoperative nausea and vomiting undergoing radiofrequency ablation in thyroid nodule:A randomized controlled trial

Objective:To observe the influence of wrist-ankle acupuncture(WAA)on postoperative nausea and vomiting(PONV)undergoing radiofrequency ablation(RFA)in thyroid nodule and its analgesic effect.Methods:A total of 66 patients with thyroid nodule and undergoing RFA were randomized into a WAA group and a sham-acupuncture(SA)group,33 cases in each one.Acupuncture was exerted after the patients entering operation room.In the WAA group,WAA was applied on the bilateral Upper 1,2 and 3 areas.In the SA group,the sham-acupuncture was given on the same areas.In 30 min after needle insertion,the routine RFA started in the patients of the two groups.All the needles were removed when the operation was finished.The proportion of intraoperative sufentanil supplementation,the incidence of24 h PONV and the proportion of intraoperative intravenous injection of urapidil were recorded in the patients of the two groups.Results:In the WAA group,sufentanil was supplemented by 12.90%,obviously less than 36.36%in the SA group.The incidence of 24 h PONV was 9.68%in the WAA group,remarkably lower than 27.27%in the SA group,indicating statistical significances(both P<0.05).The intravenous injection of urapidil was not applied during operation in the two groups,without statistical difference between the groups(P>0.05).Conclusion:Wrist-ankle acupuncture reduces the intraoperative demand of sufentanil in radiofrequency ablation of thyroid nodule and this therapy is preventive for PONV.

Wrist-Ankle Acupuncture and Ginger Moxibustion for Preventing Gastrointestinal Reactions to Chemotherapy:A Randomized Controlled Trial

Objective： To evaluate the effects of wrist-ankle acupuncture combined with ginger moxibustion against gastrointestinal tract reactions （nausea, vomiting, and constipation） to chemotherapy in cancer patients. Methods： A total of 60 patients with gynecological tumors treated by chemotherapy were randomly divided into two groups. The treatment group （30 cases） underwent wrist-ankle acupuncture and ginger moxibustion, whereas tropisetron hydrochloride and dexamethasone were intravenously administered to the control group （30 cases） during chemotherapy. Results： The frequency of nausea in the treatment group was significantly less than that of the control group from the 2nd to the 5th day of chemotherapy （P〈0.01）. The anti-emetic effect in the treatment group was significantly better than that in the control group on the 3rd day of therapy （P〈0.05）. The incidence rate of constipation was significantly lower in the treatment group than that in the control group （P〈0.01）. Furthermore, the cost of therapy for the treatment group was significantly lower than that of the control group （P〈0.01）. Only 1 patient manifested a post-acupuncture side effect in the form of subcutaneous blood stasis. Conclusion： Wrist-ankle acupuncture combined with ginger moxibustion could prevent gastrointestinal tract reactions to chemotherapy in cancer patients. In addition, the proposed method had fewer side effects, lower cost, and less risk.

Wrist–ankle acupuncture combined with pinching along the spine for children allergic rhinitis: A randomized controlled trial

Objective:To investigate the clinical effect of wrist–ankle acupuncture combined with pinching along the spine on allergic rhinitis(AR)in children.Methods:A total of 65 children with AR were collected from February 2017 through to December 2018 and they were randomly divided into a combined treatment group with wrist–ankle acupuncture,pinching along the spine and western medication(combined treatment group,32 cases)and a western medication group(33 cases).In the western medication group,loratadine was prescribed for oral administration.In the combined treatment group,on the base of the medication as the western medication group,the wrist–ankle acupuncture was adopted in combination with pinching along the spine.Before and after treatment,the symptoms and physical signs were scored and the clinical effect was observed in the children of the two groups.Results:After the treatment and in the follow-up,the scores of the symptoms and physical signs in the combined treatment group were lower than those of the western medication group,indicating a statistical significance(all P<0.05).The total effective rate was 93.7%in the combined treatment group,which was higher than 63.63%in the western medication group,indicating a statistical significance(P<0.05).Conclusion:The combined treatment of wrist–ankle acupuncture combined with pinching along the spine and loratadine effectively relieves the clinical symptoms and the physical signs in AR children.The clinical effect of this combined treatment is better than the simple use of loratadine.

Effect of wrist-ankle acupuncture on propofol dosage in painless bronchoscopy of elderly patients:A randomized controlled trial

Objective:To observe whether wrist-ankle acupuncture can reduce propofol dosage in painless bronchoscopy of elderly patients or not and its potential effect mechanism.Methods:A total of 60 patients undergoing painless bronchoscopy were randomized into a wrist-ankle acupuncture group and a control group,30 cases in each one.In the wrist-ankle acupuncture group,wrist-ankle acupuncture was received and the needles were retained for 30 min before entering to the operating room.In the control group,no any intervention was provided.The patients in two groups all received venous administration of midazolam,nalorphine and lidocaine and target controlled infusion of propofol.When the patient’s consciousness was lost and the eyelash reflex disappeared,bronchoscopy was performed and the propofol dosage was increased accordingly during operation.Propofol dosage,vital signs and occurrence of adverse reactions,bronchoscopist satisfaction,operation time and recovering time were recorded in the patients of two groups.Results:Propofol dosage in induction period and the total dosage of propofol in the wrist-ankle acupuncture group were lower than those in the control group,indicating the statistical differences(both P<0.05).The vital signs were stable during bronchoscopy in patients of two groups.The occurrence rates of hypoxemia and choking in the wrist-ankle acupuncture groups were lower than those in the control group,indicating the statistical differences(both P <0.05).Bronchoscopist satisfaction in the wrist-ankle acupuncture group was higher than that of the control group,and the operation time and recovering time were lower than the control group,indicating the statistical differences(all P<0.05).Conclusion:In painless bronchoscopy,wrist-ankle acupuncture may effectively reduce propofol dosage,alleviate respiratory suppression,reduce adverse reaction and shorten the recovering time in elderly patients.

Treatment of Ankle Sprain by Intradermal Acupuncture and Magnetic Therapy in 34 Cases

Treatment of 34 cases of Simple ankle sprain mainly by Ashi point and in cooperation with magnetic therapy, and Qiuxu (GB40), Shenmai(BL62), Jinmen (BL 63) and Pucan (BL 61) were added in the presence of strephenopodia sprain, Zhaohai (KI 6), Shuiquan (KI 5) and Taixi (KI 3) were added in the presence of strephexopodia sprain, the effective rate was 91.7%. Key Words Acupuncture-Moxibustion - Electromangetic Acupuncture - Ankle Joint - Sprains Author: Wang Hong-bin (1971-), male, acupuncturistTranslator: XIAO Yuan-chun

Treatment of 18 Orchitis Cases by Wrist- ankle Acupuncture

Needle embedding at the first region of ankle acupuncture plus fomentation was used to treat 18 orchitis cases. The curative rate was 100%. Key Words Acupuncture Therapy - Ankle Acupuncture - Orchitis Author: BAI Shu-xiang (1955-), male, attending physicianTranslator: HUANG Guo-qi

苏筋通络方结合“行气活血”针刺法治疗急性踝关节扭伤临床观察

目的观察苏筋通络方结合“行气活血”针刺法治疗急性踝关节扭伤临床效果。方法将医院创伤骨科门急诊就诊的102例急性踝关节扭伤患者(2020年5月—2022年7月)纳入研究,以随机数字表法将患者分为两组,每组51例,对照组采取西医常规治疗,观察组采取西医常规治疗同时结合苏筋通络方及“行气活血”针刺法治疗。数据比较:临床治疗效果、中医症状(踝关节疼痛肿胀、皮下瘀斑、关节活动受限等)积分变化、踝关节跖屈活动度与背伸活动度变化、视觉模拟评分(Visual Analogue Scale,VAS)变化、美国足踝外科协会(American Orthopaedic Foot and Ankle Society,AOFAS)踝-后足评分变化、血清疼痛物质(神经生长因子、神经肽、P物质)水平变化、白细胞介素-6(Interleukin-6,IL-6)、白细胞介素-1β(Interleukin-1β,IL-1β)、超敏C反应蛋白(Hypersensitive C-reactive protein,hs-CRP)变化。结果观察组患者与对照组患者治疗总有效率相比[98.04%(50/51)vs86.27%(44/51)],P<0.05;治疗后各组患者中医症状(踝关节疼痛肿胀、皮下瘀斑、关节活动受限等)积分、踝关节跖屈活动度与背伸活动度、VAS评分、AOFAS踝-后足评分、神经生长因子、神经肽、P物质、IL-6、IL-1β、hs-CRP等指标均改善,观察组患者治疗后中医症状(踝关节疼痛肿胀、皮下瘀斑、关节活动受限等)积分、踝关节跖屈活动度与背伸活动度、VAS评分、AOFAS踝-后足评分、神经生长因子、神经肽、P物质、IL-6、IL-1β、hs-CRP等指标均明显优于对照组患者,P均<0.05。结论苏筋通络方结合“行气活血”针刺法治疗急性踝关节扭伤临床效果显著,患者经治疗后临床症状显著改善,疼痛缓解,踝关节功能改善,值得应用。

子午流注腕踝针疗法防治化疗所致恶心呕吐的效果研究

目的探讨子午流注腕踝针疗法防治化疗所致恶心呕吐的临床效果。方法选取接受静脉化疗的肿瘤患者212例住院患者随机分为观察组107例、对照组105例。对照组采用常规护理方法,观察组在对照组的基础上给予腕踝针干预治疗。观察化疗后所致恶心呕吐发生率、严重程度、焦虑抑郁、日常生活能力。结果观察组患者化疗后第6天恶心呕吐发生率、严重程度、焦虑抑郁低于对照组(P<0.01),观察组患者化疗后第6天日常生活能力高于对照组(P<0.01)。结论子午流注腕踝针疗法可有效降低化疗所致肿瘤患者恶心呕吐发生率及严重程度,缓解焦虑情绪,提高生存质量具有较好的临床效果。

灵龟八法开穴法联合腕踝针对ⅢB、Ⅳ期非小细胞肺癌患者化疗所致恶心呕吐的影响

目的探究灵龟八法开穴法联合腕踝针对ⅢB、Ⅳ期非小细胞肺癌(non-small cell lung carcinoma,NSCLC)患者化疗所致恶心呕吐(chemotherapy-induced nausea and vomiting,CINV)的影响。方法选取2021年10月至2022年12月于青岛市中医医院就诊的190例ⅢB、Ⅳ期NSCLC患者为研究对象,按照随机数字表法分为观察组和对照组,每组95例。通过倾向性评分匹配后,两组分别纳入40例。比较两组患者化疗后第1、4天CINV发生情况以及化疗前后生活质量得分情况;对比分析两组患者化疗前及化疗后第1、3、5天的胃动素(motilin,MTL)、胃泌素(gastrin,GAS)、血管活性肽(vasoactive intestinal peptide,VIP)水平变化;采用广义估计方程评价两组患者治疗前后胃肠激素水平变化情况。结果化疗后第1天,两组患者在恶心呕吐发生率、恶心严重程度和呕吐次数方面差异均无统计学意义(P>0.05);化疗后第4天,观察组患者的恶心呕吐发生率、恶心严重程度和呕吐次数均低于对照组(P<0.05)。化疗前,两组患者在各项生活质量评分方面差异无统计学意义(P>0.05);化疗后,观察组患者在生理状态、躯体活动、情感状况、肺癌相关症状以及总分方面均高于对照组(P<0.05)。化疗前和化疗后第1天,两组患者MTL、GAS、VIP水平差异均无统计学意义(P>0.05);化疗后第3、5天,观察组MTL水平高于对照组、VIP水平低于对照组(P<0.05);化疗后第3天,观察组GAS水平低于对照组(P<0.05)。两组患者治疗前后MTL、GAS及VIP水平变化差异均具有统计学意义(P<0.05)。结论灵龟八法开穴法联合腕踝针对ⅢB、Ⅳ期NSCLC患者CINV具有较好的治疗效果,且能够升高MTL水平、降低GAS和VIP水平以调节胃肠激素平衡,在癌症疾病治疗中有重要意义。

腕踝针联合药物罐治疗寒湿痹阻型肩周炎临床观察

目的观察腕踝针联合药物罐治疗寒湿痹阻型肩周炎的临床效果。方法将80例寒湿痹阻型肩周炎患者随机分为A组、B组、C组和D组,每组20例。A组采用口服双氯芬酸钠缓释片治疗,B组、C组和D组在A组基础上分别采用腕踝针、药物罐及腕踝针联合药物罐治疗。观察各组治疗前后视觉模拟量表(VAS)评分、肩关节功能Mallet评分的变化情况,以及各组临床效果。结果各组治疗后1 d、7 d、14 d、21 d的VAS及肩关节功能Mallet评分与治疗前比较,差异均有统计学意义(P<0.05);治疗后1 d、7 d、14 d、21 d,B组、C组和D组VAS及肩关节功能Mallet评分与A组比较,差异均有统计学意义(P<0.05),D组VAS及Mallet评分与B组和C组比较,差异均有统计学意义(P<0.05)。结论腕踝针联合药物罐治疗寒湿痹阻型肩周炎效果确切,能有效改善患者肩关节疼痛及活动受限的症状。

艾灸联合腕踝针治疗腰椎间盘突出症急性期的临床研究

目的:研究艾灸联合腕踝针治疗腰椎间盘突出症急性期的疗效。方法:将112例腰椎间盘突出症急性期患者随机分为观察组(采用艾灸联合腕踝针治疗,56例)及对照组(腕踝针治疗,56例),比较两组患者的临床疗效、中医证候积分、疼痛程度[视觉模拟量表(VAS)]、腰椎功能[腰椎功能评估量表(JOA)]、功能障碍程度[Oswestry功能障碍指数(ODI)]及腰背肌力参数[屈曲过程表面肌电值(AEMG)、伸直过程AEMG和屈伸松弛比(FRR)]。结果:治疗2周后,观察组患者治疗总有效率较对照组高,差异具有统计学意义(P<0.05);治疗2周后,两组患者中医证候积分均降低,且观察组较对照组低,差异具有统计学意义(P<0.05);治疗1、2周后,两组患者VAS评分均降低,且观察组较对照组低,差异具有统计学意义(P<0.05);治疗2周后,两组患者JOA评分均升高,且观察组较对照组高,差异具有统计学意义(P<0.05);治疗2周后,两组患者ODI评分均降低,且观察组较对照组低,差异具有统计学意义(P<0.05);治疗2周后,两组患者屈曲过程AEMG及FRR均降低,且观察组较对照组低,差异具有统计学意义(P<0.05),伸直过程AEMG均升高,且观察组较对照组高,差异具有统计学意义(P<0.05);治疗2周后,两组患者TNF-α、CRP及IL-6水平均降低,且观察组更低,差异具有统计学意义(P<0.05)。结论:采用艾灸联合腕踝针治疗腰椎间盘突出症急性期患者可减轻其疼痛程度,且疗效较好,同时改善其腰椎功能及腰背肌力,减轻炎症反应,促进其功能恢复。

腕踝针疗法在股骨粗隆间骨折术后镇痛中的应用

目的 探究在股骨粗隆间骨折术后使用腕踝针疗法进行干预的效果。方法 选取南昌市洪都中医院收治的80例股骨粗隆间骨折患者作为研究对象,所处时间均在2019年3月—2021年3月,按镇痛方式的差异将其分为常规组和观察组,每组40例,其中常规组采用常规疼痛干预措施,观察组在常规组的基础上采用腕踝针疗法。对比2组患者麻醉消失后不同时间段的疼痛数字评价量表(NRS)分值变化情况,观察2组患者匹兹堡睡眠质量指数(PSQI)分值。结果 观察组在干预后各时间段的NRS分值、PSQI分值均低于常规组(P<0.05)。结论 在股骨粗隆间骨折术后使用腕踝针疗法进行干预,可有效改善患者的疼痛程度,改善其睡眠质量,起到较好的镇痛作用,利于患者术后恢复。

恢刺法治疗腓总神经损伤踝背屈功能疗效观察

目的 比较恢刺法与常规针刺法对腓总神经损伤的疗效差异。方法 采用回顾性队列研究方法,收集2018年3月至2022年10月河南省儿童医院康复科住院和门诊收治的腓总神经损伤患儿的临床资料,根据治疗方案不同分为恢刺组和常规针刺组,每组各收集20例,共40例。两组均选择患侧下肢阳陵泉、足三里、三阴交、解溪、太冲等穴位,恢刺组在常规取穴基础上予以行针,常规针刺组在针刺得气后予以平补平泻,每次留针30 min。两组均每日1次,每周5次,4周(20次)为1个疗程,共治疗8周(2个疗程)后评定疗效。观察两组治疗效果及下肢运动功能评估、足背屈角度变化。结果 治疗后恢刺组总有效率为90.0%(18/20),显著高于常规针刺组60.0%(12/20),差异有统计学意义(P<0.05)。治疗后,恢刺组Fugl-Meyer运动功能评分及踝关节背屈活动度改善程度明显高于常规针刺组,差异有统计学意义(P<0.05)。结论 恢刺法在改善下肢运动功能和踝关节活动度方面治疗效果优于常规针刺法,值得临床推广应用。

腕踝针治疗带状疱疹后神经痛临床疗效及对血清炎症因子水平的影响

目的:探讨腕踝针治疗带状疱疹后神经痛(postherpetic neuralgia,PHN)病人的临床疗效及对血清炎症因子水平的影响。方法:选取2023年5月至2024年3月就诊于福建中医药大学附属第二人民医院的88例PHN病人,采用随机数字表法分为观察组和对照组,每组44例,对照组给予普瑞巴林口服治疗,观察组接受腕踝针治疗,疗程均为4周。采用视觉模拟评分法(visual analogue scale,VAS)评估两组治疗前、治疗后7、14、28天的疼痛程度。比较两组治疗前、治疗4周后匹兹堡睡眠质量指数(Pittsburg sleep quality index,PSQI)、焦虑自评量表(self-rating anxiety scale,SAS)和抑郁自评量表(self-rating depression scale,SDS)评分及血清炎症因子水平变化情况,并对两组进行临床疗效评价;同时记录两组病人使用应急镇痛药物及不良反应发生情况。结果:观察组和对照组各脱落2例,各42例纳入分析。两组治疗后7、14、28天VAS评分均较治疗前显著降低(P<0.05),且观察组治疗后各时间点VAS评分均低于对照组(P<0.05)。两组治疗前PSQI评分、SAS评分、SDS评分及血清IL-6、TNF-α和CRP水平比较无显著差异,观察组治疗后PSQI评分、SAS评分、SDS评分及血清IL-6、TNF-α和CRP水平均显著低于对照组(P<0.05)。观察组临床总有效率为90.5%,对照组临床总有效率为83.3%(P>0.05)。治疗期间观察组服用应急镇痛药物5例,对照组服用应急镇痛药物11例(P>0.05)。观察组病人不良反应率为9.52%(4/42),显著低于对照组的28.57%(12/42)。结论:腕踝针治疗PHN病人疗效显著,可有效降低VAS评分、改善睡眠质量及调节负性情绪、抑制炎性因子水平、总体临床疗效不劣于对照组,且不良反应低于对照组,值得临床推广应用。