Analyses made among four radiotherapy schedules for NPC in order to determine whether there is an impact of radiotherapy course length on treatment results.A series of 320 NPC patients were divided into four radiati...Analyses made among four radiotherapy schedules for NPC in order to determine whether there is an impact of radiotherapy course length on treatment results.A series of 320 NPC patients were divided into four radiation treatment branches each with a schedule, this clinical trial was non-randomized.Radiotherapy course length factor was considered with a derivative LQ model formula that biological effective dose(BED)=nd[1 +d/(α/β)]-(T-28).The four branches were:1.split-course 103 cases, with an intermediary rest of 3-4 weeks,mean total dose 70Gy/35fx,73d, BED 51.6 Gy; 2.continuous 115 cases, 72Gy/36fx, 61d, BED 62.6 Gy;3.hyperfractionation I 52 cases, 1.5 Gy b.i.d.,time interval(Ti)≥6 hr, 75Gy/49fx,57d,BED 65.5Gy;4. hyperfractionation Ⅱ 50 cases, 1.2 Gy b.i.d., Ti≥6hr,76Gy/60fx,59d,BED 63.0 Gy.Treatment results were compared with 1-, and 3-year loco-regional recurrent rates,and 1-,and 3-year survival rates, and these rates were of a negative interrelation with prolonged course duration, but of a positive one with BED valas.Continuous branch was of a course mean 12 days shorter than the spilt-course one, its treatment results were nearly 10% higher in some subgroups;and hyperfractionation branches were slightly better than continuous one.展开更多
Innovation and entrepreneurship education is becoming one of the important goals of higher education in China.According to the requirements of the Ministry of Education to deepen the reform of innovation and entrepren...Innovation and entrepreneurship education is becoming one of the important goals of higher education in China.According to the requirements of the Ministry of Education to deepen the reform of innovation and entrepreneur-ship education in colleges and universities,we propose a core principle of“from basis to comprehensiveness,and then to innovation”to construct the software design and programming practice course in the information and communication engineering discipline.We have integrated specialized knowledge teaching with innovation and entrepreneurship training,implemented a series of experimental projects that integrate theory with practice,and explored mixed teaching methods and diversified examination methods.In this paper,details about software design and programming practice course construction are shown from aspects of teaching content,teaching methods,and examination methods.These course construction experiences will benefit teachers who engage in innovative practical courses in the information and communication engineering discipline.展开更多
文摘Analyses made among four radiotherapy schedules for NPC in order to determine whether there is an impact of radiotherapy course length on treatment results.A series of 320 NPC patients were divided into four radiation treatment branches each with a schedule, this clinical trial was non-randomized.Radiotherapy course length factor was considered with a derivative LQ model formula that biological effective dose(BED)=nd[1 +d/(α/β)]-(T-28).The four branches were:1.split-course 103 cases, with an intermediary rest of 3-4 weeks,mean total dose 70Gy/35fx,73d, BED 51.6 Gy; 2.continuous 115 cases, 72Gy/36fx, 61d, BED 62.6 Gy;3.hyperfractionation I 52 cases, 1.5 Gy b.i.d.,time interval(Ti)≥6 hr, 75Gy/49fx,57d,BED 65.5Gy;4. hyperfractionation Ⅱ 50 cases, 1.2 Gy b.i.d., Ti≥6hr,76Gy/60fx,59d,BED 63.0 Gy.Treatment results were compared with 1-, and 3-year loco-regional recurrent rates,and 1-,and 3-year survival rates, and these rates were of a negative interrelation with prolonged course duration, but of a positive one with BED valas.Continuous branch was of a course mean 12 days shorter than the spilt-course one, its treatment results were nearly 10% higher in some subgroups;and hyperfractionation branches were slightly better than continuous one.
基金This work is supported by the Teaching Reform Project of Harbin Engineering University under Grant JG2021B0806.
文摘Innovation and entrepreneurship education is becoming one of the important goals of higher education in China.According to the requirements of the Ministry of Education to deepen the reform of innovation and entrepreneur-ship education in colleges and universities,we propose a core principle of“from basis to comprehensiveness,and then to innovation”to construct the software design and programming practice course in the information and communication engineering discipline.We have integrated specialized knowledge teaching with innovation and entrepreneurship training,implemented a series of experimental projects that integrate theory with practice,and explored mixed teaching methods and diversified examination methods.In this paper,details about software design and programming practice course construction are shown from aspects of teaching content,teaching methods,and examination methods.These course construction experiences will benefit teachers who engage in innovative practical courses in the information and communication engineering discipline.
