Due to the complex nature of multi-source geological data, it is difficult to rebuild every geological structure through a single 3D modeling method. The multi-source data interpretation method put forward in this ana...Due to the complex nature of multi-source geological data, it is difficult to rebuild every geological structure through a single 3D modeling method. The multi-source data interpretation method put forward in this analysis is based on a database-driven pattern and focuses on the discrete and irregular features of geological data. The geological data from a variety of sources covering a range of accuracy, resolution, quantity and quality are classified and integrated according to their reliability and consistency for 3D modeling. The new interpolation-approximation fitting construction algorithm of geological surfaces with the non-uniform rational B-spline(NURBS) technique is then presented. The NURBS technique can retain the balance among the requirements for accuracy, surface continuity and data storage of geological structures. Finally, four alternative 3D modeling approaches are demonstrated with reference to some examples, which are selected according to the data quantity and accuracy specification. The proposed approaches offer flexible modeling patterns for different practical engineering demands.展开更多
In order to detect fault exactly and quickly, cusp catastrophe theory is used to interpret 3D coal seismic data in this paper. By establishing a cusp model, seismic signal is transformed into standard form of cusp cat...In order to detect fault exactly and quickly, cusp catastrophe theory is used to interpret 3D coal seismic data in this paper. By establishing a cusp model, seismic signal is transformed into standard form of cusp catastrophe and catastrophe parameters, including time-domain catastrophe potential, time-domain catastrophe time, frequency-domain catastrophe potential and frequency- domain degree, are calculated. Catastrophe theory is used in 3D seismic structural interpretation in coal mine. The results show that the position of abnormality of the catastrophe parameter profile or curve is related to the location of fault, and the cusp catastrophe theory is effective to automatically pick up geology information and improve the interpretation precision in 3D seismic data.展开更多
Branching river channels and the coexistence of valleys, ridges, hiils, and slopes'as the result of long-term weathering and erosion form the unique loess topography. The Changqing Geophysical Company, working in the...Branching river channels and the coexistence of valleys, ridges, hiils, and slopes'as the result of long-term weathering and erosion form the unique loess topography. The Changqing Geophysical Company, working in these complex conditions, has established a suite of technologies for high-fidelity processing and fine interpretation of seismic data. This article introduces the processes involved in the data processing and interpretation and illustrates the results.展开更多
The Pennsylvanian unconformity,which is a detrital surface,separates the beds of the Permian-aged strata from the Lower Paleozoic in the Central Basin Platform.Seismic data interpretation indicates that the unconformi...The Pennsylvanian unconformity,which is a detrital surface,separates the beds of the Permian-aged strata from the Lower Paleozoic in the Central Basin Platform.Seismic data interpretation indicates that the unconformity is an angular unconformity,overlying multiple normal faults,and accompanied with a thrust fault which maximizes the region's structural complexity.Additionally,the Pennsylvanian angular unconformity creates pinch-outs between the beds above and below.We computed the spectral decomposition and reflector convergence attributes and analyzed them to characterize the angular unconformity and faults.The spectral decomposition attribute divides the broadband seismic data into different spectral bands to resolve thin beds and show thickness variations.In contrast,the reflector convergence attribute highlights the location and direction of the pinch-outs as they dip south at angles between 2° and 6°.After reviewing findings from RGB blending of the spectrally decomposed frequencies along the Pennsylvanian unconformity,we observed channel-like features and multiple linear bands in addition to the faults and pinch-outs.It can be inferred that the identified linear bands could be the result of different lithologies associated with the tilting of the beds,and the faults may possibly influence hydrocarbon migration or act as a flow barrier to entrap hydrocarbon accumulation.The identification of this angular unconformity and the associated features in the study area are vital for the following reasons:1)the unconformity surface represents a natural stratigraphic boundary;2)the stratigraphic pinch-outs act as fluid flow connectivity boundaries;3)the areal extent of compartmentalized reservoirs'boundaries created by the angular unconformity are better defined;and 4)fault displacements are better understood when planning well locations as faults can be flow barriers,or permeability conduits,depending on facies heterogeneity and/or seal effectiveness of a fault,which can affect hydrocarbon production.The methodology utilized in this study is a further step in the characterization of reservoirs and can be used to expand our knowledge and obtain more information about the Goldsmith Field.展开更多
This documentary research aimed to describe the results of an epidemiological survey that sought to determine the prevalence of Infections Related to Health Care (IRHC) in newborns admitted to a Neonatal Intensive Car...This documentary research aimed to describe the results of an epidemiological survey that sought to determine the prevalence of Infections Related to Health Care (IRHC) in newborns admitted to a Neonatal Intensive Care Unit (NICU) at the city of Rio de Janeiro. For methodology, the existing data in the original research database were used as the primary source. The method used was the case study in a quantitative approach. The data have been statistically arranged by odds ratio, which measured the possibility of IRHC development at the 102 newborns, by exposition at the risk factors. Results: IRHC prevalence with pneumonias, sepsis, navel’s infection and ocular infections predominance rises. Prematures are 4.10 more susceptible. Twelve hours after amniotic rupture there are 1.77 more chances of infections. Babies with more than 10 days of hospitalization are 4.70 more susceptible than those with 10 days. The registers examined were incipient at the IRHC’s characterization, beginning and duration, which make the IRHC’s diagnostic/notification difficult.展开更多
Linear and circular interpretation structure maps of different relative depths are obtained by processing 1:200000 aeromagnetic data to the pole in Ailaoshan region,interpreting upward extension of 4 heights,extractin...Linear and circular interpretation structure maps of different relative depths are obtained by processing 1:200000 aeromagnetic data to the pole in Ailaoshan region,interpreting upward extension of 4 heights,extracting a vertical second derivative line of 0 value and a series of calculations. Concealed boundary of deep magnetic rocks can be delineated according to the maps. On the basis of the conclusions above,a set of economical and practical methods to graph the deep structure are summarized. In addition,the relationship between deep structure and mineralization positions is discussed.展开更多
Deep learning technologies are increasingly used in the fi eld of geophysics,and a variety of algorithms based on shallow convolutional neural networks are more widely used in fault recognition,but these methods are u...Deep learning technologies are increasingly used in the fi eld of geophysics,and a variety of algorithms based on shallow convolutional neural networks are more widely used in fault recognition,but these methods are usually not able to accurately identify complex faults.In this study,using the advantage of deep residual networks to capture strong learning features,we introduce residual blocks to replace all convolutional layers of the three-dimensional(3D)UNet to build a new 3D Res-UNet and select appropriate parameters through experiments to train a large amount of synthesized seismic data.After the training is completed,we introduce the mechanism of knowledge distillation.First,we treat the 3D Res-UNet as a teacher network and then train the 3D Res-UNet as a student network;in this process,the teacher network is in evaluation mode.Finally,we calculate the mixed loss function by combining the teacher model and student network to learn more fault information,improve the performance of the network,and optimize the fault recognition eff ect.The quantitative evaluation result of the synthetic model test proves that the 3D Res-UNet can considerably improve the accuracy of fault recognition from 0.956 to 0.993 after knowledge distillation,and the eff ectiveness and feasibility of our method can be verifi ed based on the application of actual seismic data.展开更多
The purpose of this study was to investigate the nuclear magnetic resonance (NMR) assignments of hydrolyzed products extracted from human blood plasma. The correlations between chemical, functional and structural pr...The purpose of this study was to investigate the nuclear magnetic resonance (NMR) assignments of hydrolyzed products extracted from human blood plasma. The correlations between chemical, functional and structural prop- erties of highly toxic pesticides were investigated using the PreADME analysis. We observed that toxic pesticides possessed higher molecular weight and, more hydrogen bond donors and acceptors when compared with less toxic pesticides. The occurrence of functional groups and structural properties was analyzed using ~H-NMR. The ~H- NMR spectra of the phosphomethoxy class of pesticides were characterized by methyl resonances at 3.7-3.9 ppm (8) with the coupling constants of 11-16 Hz (Je-cns). In phosphoethoxy pesticides, the methyl resonance was about 1.4 ppm (8) with the coupling constant of 10 Hz (Je-cH2) and the methylene resonances was 4.2-4.4 ppm (8) with the coupling constant of 0.8 Hz (Jp-cH3), respectively. Our study shows that the values of four parameters such as chemical shift, coupling constant, integration and relaxation time correlated with the concentration of toxic pesticides, and can be used to characterise the proton groups in the molecular structures of toxic pesticides.展开更多
3D seismic prospecting in mining areas of Xieqiao Colliery is a successfulmodel for an advancement from the resource prospecting to mining prospecting stagein coal fields. Its results have proved that faults with a th...3D seismic prospecting in mining areas of Xieqiao Colliery is a successfulmodel for an advancement from the resource prospecting to mining prospecting stagein coal fields. Its results have proved that faults with a throw of 5-10 m can be detected in an area with good seismogeologic conditions by using 3D seismic technique.Detection of underground tunnels for the first time utilizing 3D seismic data indicates that subsided columns, gotten and mine goaf can be detected using 3D seismic technique, so it has a broad applied prospect.展开更多
Extensive oedometer tests and physical tests have been conducted on remolded and reconstituted marine soils with different initial water contents and liquid limits. The oedometer test data can be well fitted with a st...Extensive oedometer tests and physical tests have been conducted on remolded and reconstituted marine soils with different initial water contents and liquid limits. The oedometer test data can be well fitted with a straight line in the bilogarithmic ln(1+ e ) ~ lg p plot. The initial effective stress corresponding to the initial void ratio is determined by extrapolation of the bilogarithmic compression line. This new way of extrapolating oedometer test data to the initial void ratio overcomes the difficulty of measuring the residual effective stress of soils in the remolded state. The initial stable compression line of ocean floor deposits under different deposition environments corresponds to the compression line at the sensitivity equal to one. This initial stable compression line obtained in this study is consistent with the available compression line at the sensitivity equal to one which is proposed based on the experimental data of remolded undrained strength and the theoretical concept of Cam clay critical state line.展开更多
The development of spatial transcriptomics(ST)technologies has transformed genetic research from a single-cell data level to a two-dimensional spatial coordinate system and facilitated the study of the composition and...The development of spatial transcriptomics(ST)technologies has transformed genetic research from a single-cell data level to a two-dimensional spatial coordinate system and facilitated the study of the composition and function of various cell subsets in different environments and organs.The large-scale data generated by these ST technologies,which contain spatial gene expression information,have elicited the need for spatially resolved approaches to meet the requirements of computational and biological data interpretation.These requirements include dealing with the explosive growth of data to determine the cell-level and gene-level expression,correcting the inner batch effect and loss of expression to improve the data quality,conducting efficient interpretation and in-depth knowledge mining both at the single-cell and tissue-wide levels,and conducting multi-omics integration analysis to provide an extensible framework toward the in-depth understanding of biological processes.However,algorithms designed specifically for ST technologies to meet these requirements are still in their infancy.Here,we review computational approaches to these problems in light of corresponding issues and challenges,and present forward-looking insights into algorithm development.展开更多
We have developed a fuzzy neural expert system that has the precisionand learning ability of a neural network. Knowledge is acquired from domainexperts as fuzzy rules and membership functions. Then, they are converted...We have developed a fuzzy neural expert system that has the precisionand learning ability of a neural network. Knowledge is acquired from domainexperts as fuzzy rules and membership functions. Then, they are convertedinto a neural network which implements fuzzy inference without rule matching.The neural network is applied to problem-solving and learns from the dataobtained during operation to enhance the accuracy The learning ability of theneural network makes it easy to modify the membership functions defined bydomain experts. Also, by modifying the weights of neural networks adaptively,the problem of belief propagation in conventional expert systems can be solvedeasily. Converting the neural network back iato fuzzy rules and membershipfunctions helps explain the inner representation and operation of the neuralnetwork.展开更多
Phosphorylation is one of the most common post translational modifications (PTM), participating in a large number of processes to regulate cellular functions. Phosphorylation is also one of the key factors in the or...Phosphorylation is one of the most common post translational modifications (PTM), participating in a large number of processes to regulate cellular functions. Phosphorylation is also one of the key factors in the origin and development of cancer. The rapid development of mass spectrometric-based phosphoproteomic technologies has made it possible for high-throughput identification and quantification of phosphorylation events. In this review, we provide a general introduction and summary of the achievements made in mass spectrometry based phosphoproteomic research, including the approaches for phosphopeptide identification and quantification, as well as instrumentation and data interpretation methods. We also review some discoveries in cancer research made possible by phosphoproteomic analysis technologies.展开更多
基金Supported by the National Natural Science Foundation of China(No.51379006 and No.51009106)the Program for New Century Excellent Talents in University of Ministry of Education of China(No.NCET-12-0404)the National Basic Research Program of China("973"Program,No.2013CB035903)
文摘Due to the complex nature of multi-source geological data, it is difficult to rebuild every geological structure through a single 3D modeling method. The multi-source data interpretation method put forward in this analysis is based on a database-driven pattern and focuses on the discrete and irregular features of geological data. The geological data from a variety of sources covering a range of accuracy, resolution, quantity and quality are classified and integrated according to their reliability and consistency for 3D modeling. The new interpolation-approximation fitting construction algorithm of geological surfaces with the non-uniform rational B-spline(NURBS) technique is then presented. The NURBS technique can retain the balance among the requirements for accuracy, surface continuity and data storage of geological structures. Finally, four alternative 3D modeling approaches are demonstrated with reference to some examples, which are selected according to the data quantity and accuracy specification. The proposed approaches offer flexible modeling patterns for different practical engineering demands.
文摘In order to detect fault exactly and quickly, cusp catastrophe theory is used to interpret 3D coal seismic data in this paper. By establishing a cusp model, seismic signal is transformed into standard form of cusp catastrophe and catastrophe parameters, including time-domain catastrophe potential, time-domain catastrophe time, frequency-domain catastrophe potential and frequency- domain degree, are calculated. Catastrophe theory is used in 3D seismic structural interpretation in coal mine. The results show that the position of abnormality of the catastrophe parameter profile or curve is related to the location of fault, and the cusp catastrophe theory is effective to automatically pick up geology information and improve the interpretation precision in 3D seismic data.
文摘Branching river channels and the coexistence of valleys, ridges, hiils, and slopes'as the result of long-term weathering and erosion form the unique loess topography. The Changqing Geophysical Company, working in these complex conditions, has established a suite of technologies for high-fidelity processing and fine interpretation of seismic data. This article introduces the processes involved in the data processing and interpretation and illustrates the results.
文摘The Pennsylvanian unconformity,which is a detrital surface,separates the beds of the Permian-aged strata from the Lower Paleozoic in the Central Basin Platform.Seismic data interpretation indicates that the unconformity is an angular unconformity,overlying multiple normal faults,and accompanied with a thrust fault which maximizes the region's structural complexity.Additionally,the Pennsylvanian angular unconformity creates pinch-outs between the beds above and below.We computed the spectral decomposition and reflector convergence attributes and analyzed them to characterize the angular unconformity and faults.The spectral decomposition attribute divides the broadband seismic data into different spectral bands to resolve thin beds and show thickness variations.In contrast,the reflector convergence attribute highlights the location and direction of the pinch-outs as they dip south at angles between 2° and 6°.After reviewing findings from RGB blending of the spectrally decomposed frequencies along the Pennsylvanian unconformity,we observed channel-like features and multiple linear bands in addition to the faults and pinch-outs.It can be inferred that the identified linear bands could be the result of different lithologies associated with the tilting of the beds,and the faults may possibly influence hydrocarbon migration or act as a flow barrier to entrap hydrocarbon accumulation.The identification of this angular unconformity and the associated features in the study area are vital for the following reasons:1)the unconformity surface represents a natural stratigraphic boundary;2)the stratigraphic pinch-outs act as fluid flow connectivity boundaries;3)the areal extent of compartmentalized reservoirs'boundaries created by the angular unconformity are better defined;and 4)fault displacements are better understood when planning well locations as faults can be flow barriers,or permeability conduits,depending on facies heterogeneity and/or seal effectiveness of a fault,which can affect hydrocarbon production.The methodology utilized in this study is a further step in the characterization of reservoirs and can be used to expand our knowledge and obtain more information about the Goldsmith Field.
文摘This documentary research aimed to describe the results of an epidemiological survey that sought to determine the prevalence of Infections Related to Health Care (IRHC) in newborns admitted to a Neonatal Intensive Care Unit (NICU) at the city of Rio de Janeiro. For methodology, the existing data in the original research database were used as the primary source. The method used was the case study in a quantitative approach. The data have been statistically arranged by odds ratio, which measured the possibility of IRHC development at the 102 newborns, by exposition at the risk factors. Results: IRHC prevalence with pneumonias, sepsis, navel’s infection and ocular infections predominance rises. Prematures are 4.10 more susceptible. Twelve hours after amniotic rupture there are 1.77 more chances of infections. Babies with more than 10 days of hospitalization are 4.70 more susceptible than those with 10 days. The registers examined were incipient at the IRHC’s characterization, beginning and duration, which make the IRHC’s diagnostic/notification difficult.
基金Project supported by National Key Technology R &D Program (No.2006BAB01B10)
文摘Linear and circular interpretation structure maps of different relative depths are obtained by processing 1:200000 aeromagnetic data to the pole in Ailaoshan region,interpreting upward extension of 4 heights,extracting a vertical second derivative line of 0 value and a series of calculations. Concealed boundary of deep magnetic rocks can be delineated according to the maps. On the basis of the conclusions above,a set of economical and practical methods to graph the deep structure are summarized. In addition,the relationship between deep structure and mineralization positions is discussed.
基金supported by the National Natural Science Foundation of China(No.42072169)。
文摘Deep learning technologies are increasingly used in the fi eld of geophysics,and a variety of algorithms based on shallow convolutional neural networks are more widely used in fault recognition,but these methods are usually not able to accurately identify complex faults.In this study,using the advantage of deep residual networks to capture strong learning features,we introduce residual blocks to replace all convolutional layers of the three-dimensional(3D)UNet to build a new 3D Res-UNet and select appropriate parameters through experiments to train a large amount of synthesized seismic data.After the training is completed,we introduce the mechanism of knowledge distillation.First,we treat the 3D Res-UNet as a teacher network and then train the 3D Res-UNet as a student network;in this process,the teacher network is in evaluation mode.Finally,we calculate the mixed loss function by combining the teacher model and student network to learn more fault information,improve the performance of the network,and optimize the fault recognition eff ect.The quantitative evaluation result of the synthetic model test proves that the 3D Res-UNet can considerably improve the accuracy of fault recognition from 0.956 to 0.993 after knowledge distillation,and the eff ectiveness and feasibility of our method can be verifi ed based on the application of actual seismic data.
文摘The purpose of this study was to investigate the nuclear magnetic resonance (NMR) assignments of hydrolyzed products extracted from human blood plasma. The correlations between chemical, functional and structural prop- erties of highly toxic pesticides were investigated using the PreADME analysis. We observed that toxic pesticides possessed higher molecular weight and, more hydrogen bond donors and acceptors when compared with less toxic pesticides. The occurrence of functional groups and structural properties was analyzed using ~H-NMR. The ~H- NMR spectra of the phosphomethoxy class of pesticides were characterized by methyl resonances at 3.7-3.9 ppm (8) with the coupling constants of 11-16 Hz (Je-cns). In phosphoethoxy pesticides, the methyl resonance was about 1.4 ppm (8) with the coupling constant of 10 Hz (Je-cH2) and the methylene resonances was 4.2-4.4 ppm (8) with the coupling constant of 0.8 Hz (Jp-cH3), respectively. Our study shows that the values of four parameters such as chemical shift, coupling constant, integration and relaxation time correlated with the concentration of toxic pesticides, and can be used to characterise the proton groups in the molecular structures of toxic pesticides.
文摘3D seismic prospecting in mining areas of Xieqiao Colliery is a successfulmodel for an advancement from the resource prospecting to mining prospecting stagein coal fields. Its results have proved that faults with a throw of 5-10 m can be detected in an area with good seismogeologic conditions by using 3D seismic technique.Detection of underground tunnels for the first time utilizing 3D seismic data indicates that subsided columns, gotten and mine goaf can be detected using 3D seismic technique, so it has a broad applied prospect.
文摘Extensive oedometer tests and physical tests have been conducted on remolded and reconstituted marine soils with different initial water contents and liquid limits. The oedometer test data can be well fitted with a straight line in the bilogarithmic ln(1+ e ) ~ lg p plot. The initial effective stress corresponding to the initial void ratio is determined by extrapolation of the bilogarithmic compression line. This new way of extrapolating oedometer test data to the initial void ratio overcomes the difficulty of measuring the residual effective stress of soils in the remolded state. The initial stable compression line of ocean floor deposits under different deposition environments corresponds to the compression line at the sensitivity equal to one. This initial stable compression line obtained in this study is consistent with the available compression line at the sensitivity equal to one which is proposed based on the experimental data of remolded undrained strength and the theoretical concept of Cam clay critical state line.
基金We thank Ying Zhang,Chao Liu,and Ping Qiu for their assistance for the manuscript.
文摘The development of spatial transcriptomics(ST)technologies has transformed genetic research from a single-cell data level to a two-dimensional spatial coordinate system and facilitated the study of the composition and function of various cell subsets in different environments and organs.The large-scale data generated by these ST technologies,which contain spatial gene expression information,have elicited the need for spatially resolved approaches to meet the requirements of computational and biological data interpretation.These requirements include dealing with the explosive growth of data to determine the cell-level and gene-level expression,correcting the inner batch effect and loss of expression to improve the data quality,conducting efficient interpretation and in-depth knowledge mining both at the single-cell and tissue-wide levels,and conducting multi-omics integration analysis to provide an extensible framework toward the in-depth understanding of biological processes.However,algorithms designed specifically for ST technologies to meet these requirements are still in their infancy.Here,we review computational approaches to these problems in light of corresponding issues and challenges,and present forward-looking insights into algorithm development.
文摘We have developed a fuzzy neural expert system that has the precisionand learning ability of a neural network. Knowledge is acquired from domainexperts as fuzzy rules and membership functions. Then, they are convertedinto a neural network which implements fuzzy inference without rule matching.The neural network is applied to problem-solving and learns from the dataobtained during operation to enhance the accuracy The learning ability of theneural network makes it easy to modify the membership functions defined bydomain experts. Also, by modifying the weights of neural networks adaptively,the problem of belief propagation in conventional expert systems can be solvedeasily. Converting the neural network back iato fuzzy rules and membershipfunctions helps explain the inner representation and operation of the neuralnetwork.
文摘Phosphorylation is one of the most common post translational modifications (PTM), participating in a large number of processes to regulate cellular functions. Phosphorylation is also one of the key factors in the origin and development of cancer. The rapid development of mass spectrometric-based phosphoproteomic technologies has made it possible for high-throughput identification and quantification of phosphorylation events. In this review, we provide a general introduction and summary of the achievements made in mass spectrometry based phosphoproteomic research, including the approaches for phosphopeptide identification and quantification, as well as instrumentation and data interpretation methods. We also review some discoveries in cancer research made possible by phosphoproteomic analysis technologies.