Analysis of Imaging Characteristics and Dynamic Changes of 3 Cases of Severe Novel Coronavirus Pneumonia in Qinghai Province

Objective:To analyze the characteristics,dynamic changes,and outcomes of the first imaging manifestations of 3 patients with severe COVID-19 in our hospital.Methods:Computed tomography(CT)findings of 3 patients with severe COVID-19 who tested positive by the nucleic acid test in our hospital were selected,mainly focusing on the morphology,distribution characteristics,and dynamic changes of the first CT findings.Results:3 patients with severe pneumonia were older,with one aged 80.The first chest CT examination for all 3 patients differed.Imaging showed a leafy distribution of consolidation,primarily affecting the lower lobes of both lungs and extending subpleurally.A grid-like pattern was observed,along with changes in the consolidation and air bronchogram.These changes had slower absorption,especially in patients with underlying diseases.Conclusion:CT manifestations of severe COVID-19 have specific characteristics and the analysis of their characteristics and dynamic changes provide valuable insights for clinical treatment.

Study on the Quantity Dynamic Changes of Heterobacteria and Vibrios in Larvae Industrialized Culture System

[ Objective ] The dynamic change of heterobacteria and vibrios in larvae industrialized culture system was studied to provide scientific reference for healthy cultivation of shrimp. [ Method ] The heterobacteria, vibrios and pathogenic vibrio parahaemolyticus were monitored in larvae industrialized culture system. [ Result] The heterobacteria, vibrios and pathogenic vibrio parahaemolyticus were the most in fertilized eggs of shrimp but the least in nauplius, then their number would increase with growth. During whole rearing period, both boterobacteria in larvae, vibrios in water would increase by one order of magnitude, while both vibrios in larvae and heterobacteria in water would increase by two orders of magnitude. There were many heterobacteria and vibrios but few vibrio parahaemolyticus in living bait. The correlation coefficients between larvae and heterobacteria and vibrios in water were 0. 704 and 0. 840 in culture system respectively, while the correlation among heterobacteria, vibrios in living bait and larvae, water were weak or negative. [ Conclusion ] There was a dynamic relation between water and larvae in rearing period, and restrictly control of culture condition would restrain the occurrence of disease caused by vibrio parahaemolyticus, besides that bacteria number in bait was not obviously correlated with bacteria nubmer in culture system.

Effect of Combined Application of Manure and Chemical Fertilizer on the Dynamic Changes of Purple Soil Nutrient and Soil Enzyme Activities

[Objective] The aim was to study the effects of combined of manure and fertilizer on the content of nutrients in purplish soil as well as release dynamics of enzyme activities.[Method] The effects of manure and fertilizer application on the content of AOM,NH＋4-N and NO-3-N in soil as well as release dynamics of enzyme activities were studied by means of simulation culturing.[Result] In the treatments of combined application of simulation culture experiment,the content of active organic matters,NH＋4-N,NO-3-N and soil enzyme activities changed dynamically,which showed a shape of inverted ＂S＂ with two or more peaks.Compared with the treatment of fertilization,their peaks were relatively flat and occurred relatively late,while the treatment of fertilization had only one but the highest peak.The content of active organic matter came to top around 10 d in the order of cow5fertilizer5pig5fertilizer5cow manurepig manurefertilizer Ⅰfertilizer Ⅱ;the activity of urease came to top around 10 d in all treatments and in the order of pig manurecow5fertilizer5cow manurefertilizer Ⅰfertilizer Ⅱpig5fertilizer5.The activity of saccharase was in the order of pig5fertilizer5pig manurecow5fertilizer5cow manureCKfertilizer Ⅱfertilizer Ⅰ.[Conclusion] The study could provide the theoretical basis for reasonable application of manure and fertilizer.

Dynamic Changes of Nitrogen in Saline-alkaline Paddy Field and Its Potential Environmental Impacts

[Objective] The paper was to study the dynamic changes of nitrogen in saline-alkaline paddy field and its potential environment impacts. [Method] With typical sodic saline-alkaline paddy fields of Songnen Plain as study object,field test method was used to explore the dynamic changes was strong alkof nitrogen in paddy field of the region and its potential impact on environment. [Result] The soil in test regionaline with high CEC and C/N ratios,as well as poor preserving capacity of fertilizer. During the two-year field experiment,the indicators of salinization fluctuated. Initially,the concentrations of total nitrogen and ammonia nitrogen reached their maximum values,then decreased over time as a result of heavy rain. The maximum of nitrate concentration appeared later than those of total nitrogen and ammonia nitrogen. Ammonia volatilization accounted for 18.9%-28.8% of the nitrogen loss. The total nitrogen concentration in surface water was higher than the national Class Ⅲ surface water environmental quality standard. The concentration of ammonia from the recession flow of agricultural field was considerably high,which would potentially threaten the fishery in the downstream of Chagan Lake. [Conclusion] The study provided theoretical basis for saline-alkaline soil management and conservation of water and fishery resources.

Dynamic changes of ocular biometric parameters:a modified form-deprivation myopia model of young guinea pigs

AIM: To evaluate the dynamic ocular biometric changes of a modified form-deprivation myopia model in young guinea pigs. METHODS: The animals were randomly assigned to two groups: the monocularly deprived facemask group (MDF, with all the right eyes covered, n=24) and the normal control group(free of facemask, n=24). Each group was then equally divided into four subgroups which were followed up for 2, 4, 6 and 8 weeks, respectively. Parameters measured from every eye included refraction, corneal curvature, axial length and the dry weight of sclera at the posterior pole. RESULTS: All the facemasks remained in place during the follow-up. The covered eyes developed myopia with the vitreous chamber lengthening and the dry weight of posterior sclera reduced at each time point compared with the contralateral uncovered (P<0.05 at all time points). The changes had a linear correlation with the deprivation time (P<0.05). There were no significant differences in all the parameters between the uncovered eyes of MDF group and the normal control group (P>0.05 at all time points). CONCLUSION: Monocular form deprivation with the facemask is highly effective and non-invasive in inducing axial myopia in guinea pigs. The axial myopia is mainly caused by the increased vitreous chamber length and the weakened posterior sclera rigidity. The form-deprivation eye didn't interfere with the natural development of the contralateral eye.

Quantitative analysis of the dynamic change and spatial differences of the ecological security: a case study of Loess Plateau in northern Shaanxi Province

Using the theory and method of the ecological footprint, and combining the changes of regional land use, resource environment, population, society and economy, this paper calculated the ecological footprint, ecological carrying capacity and ecological surplus/loss in 1986-2002 on the Loess Plateau in northern Shaanxi Province. What is more, this paper has put forward the concept of ecological pressure index, set up ecological pressure index models, and ecological security grading systems, and the prediction models of different ecological footprints, ecological carrying capacity, ecological surplus and ecological safety change, and also has assessed the ecological footprint demands of 10,000 yuan GDE The results of this study are as follows： （1） the ecological carrying capacity in northern Shaanxi shows a decreasing trend, the difference of reducing range is the fastest; （2） the ecological footprint appears an increasing trend; （3） ecological pressure index rose to 0.91 from 0.44 during 1986-2002 on the Loess Plateau of northern Shaanxi with an increase of 47%; and （4） the ecological security in the study area is in a critical state, and the ecological oressure index has been increasing rapidlv.

Comparison of performance between rescaled range analysis and rescaled variance analysis in detecting abrupt dynamic change

In the present paper, a comparison of the performance between moving cutting data-rescaled range analysis （MC- R/S） and moving cutting data-rescaled variance analysis （MC-V/S） is made. The results clearly indicate that the operating efficiency of the MC-R/S algorithm is higher than that of the MC-V/S algorithm. In our numerical test, the computer time consumed by MC-V/S is approximately 25 times that by MC-R/S for an identical window size in artificial data. Except for the difference in operating efficiency, there are no significant differences in performance between MC-R/S and MC-V/S for the abrupt dynamic change detection. Mc-R/s and MC-V/S both display some degree of anti-noise ability. However, it is important to consider the influences of strong noise on the detection results of MC-R/S and MC-V/S in practical application

Dynamic Changes in DNA Damage and Repair Biomarkers with Employment Length among Nickel Smelting Workers

Our study explored the dynamic changes in andthe relationship between the DNA damage marker8-hydroxy-2＇-deoxyguanosine （8-OHdG） and theDNA repair marker 8-hydroxyguanine DNAglycosidase 1 （hOGG1） according to the length ofoccupational employment in nickel smeltingworkers. One hundred forty nickel-exposedsmelting workers and 140 age-matched unexposedoffice workers were selected from the Jinchangcohort. The 8-OHdG levels in smelting workers wassignificantly higher than in office workers （Z=-8.688,P〈0.05） and the 8-OHdG levels among nickelsmelting workers in the 10-14 y employment lengthcategory was significantly higher than among allpeers. The hOGG1 levels among smelting workerswere significantly lower than those of non-exposedworkers （Z=-8.948, P〈0.05）. There were significantdifferences between employment length andhOGG1 levels, with subjects employed in nickelsmelting for 10-14 y showing the highest levels ofhOGG1. Correlation analysis showed positivecorrelations between 8-OHdG and hOGG1 levels（r=0.413; P〈0.01）. DNA damage was increased withemployment length among nickel smelting workersand was related to the inhibition of hOGG1 repaircapacity.

Dynamic Change Analysis of Urban Green Land in Jinan City Based RS and Geo-information Tupu

The three-period (1995, 1998 and 2003) remote sensing images in Jinan City, China are selected. And the information of green land, construction land, woodland and water body is extracted by using the image processing module of remote-sensing software and computerized interpretation module. Both the change table and transfer matrix table of land use area are analyzed by modeling module of remote-sensing software. Then, the Geo-information Tupu is obtained; and the temporal and spatial variation of land use in Jinan City is monitored and analyzed by Geo-information Tupu and transfer matrix. Result shows that land use structure change of Jinan City in the years 1995-1998 shows a transformation from green land to construction land. Area of green land circulating into construction land reaches 62.27 square kilometers, accounting for 25.84% of the initial green land. In the year 1998, areas of woodland and green land are reduced due to the urban expansion of Jinan City. However, with the enhancement of people's awareness of environmental protection, areas of woodland and green land gradually increase in the year 2003, which are still less than those in the year 1995.

Dynamic Change of Landscape Pattern at Jilin Province from 1980 to 2000

By using remote sensing images from three periods (1980, 1995, 2000) and with the support of GIS and RS, the spatial information of landscape elements of Jilin Province from 1980 to 2000 was interpreted and extracted. Using models of landscape indices such as diversity, fragmentation, and mean patch fractal dimension, dynamic spatio-temporal changes of landscape patterns of the province were analyzed. The results: ① cropland and forestland were the main landscape types, and forestland became a landscape matrix; ② in the study area, landscapes were distributed unevenly, and there was low heterogeneity, a simple ecosystem structure and a tendency of irrational landscape patterns. There were also simple spatial shapes of patches and strong self-similarities, and in terms of dynamic change analysis, patch shapes tended to be more simple; ③ from 1980 to 2000, holistic landscape fragmentation was low and changed slightly. As far as landscape elements were concerned, the fragmentation of grassland, water area, land for residential area and factory facilities was relatively low; land distribution for residential areas and factory facilities was dispersed; and cropland and forestland were most concentrated-an indication that the trend will continue. Comprehensive effects among human activity, local policy, regional climate and environmental change led to the results.

Spectral-domain optical coherence tomography dynamic changes and steroid response in multiple evanescent white dot syndrome

Dear Editor,Multiple evanescent white dot syndrome （MEWDS） was first described in 1984 as a rare, acute, unilateral,multifocal retinochoroidal disorder, typically affecting young myopic women. Previous studies with fluorescein angiography （FA） and electrophysiology suggested that MEWDS to be a disease in the retinal pigment epithelium （RPE） or outer retina, while recent studies with spectral- domain optical coherence tomography （SD-OCT） suggested it may be an outer retinal disease due to observation of hyperreflective material in outer retina and subtle disruptionsof the ellipsoid zone without RPE disruption.

Dynamic changes of gravity fields before and after the 2008 Wenchuan earthquake(Ms8.0)

The pattern evolution and dynamic mechanism of the dynamic changes of regional gravity fields occurring before and after the Wenchuan Ms8.0 earthquake are analyzed, based on five epochs of 1998 -2007 mobile gravity data from the middle-south section of the north-south seismic belt, and two epochs of field research data collected after the 2008 Wenchuan earthquake in combination with GPS data, leveling observations, and geotectonic environment data. The regional dynamic gravity changes demonstrate the effects of the eastward flow of solid matter in the Qinghai-Tibetan plateau and the preparation of the 2008 Wenchuan earthquake （2- 10 yr）. The two most meaningful gravity indicators of the Wcnchuan earthquake preparation are the positive （increasing） gravity changes occurring over many years in the southwest epicenter and the largescale gradient zone of gravity variation, with the cumulative difference between the two sides of the gradient zone of gravity exceeding 200 μGal. The positive gravity changes may facilitate a constant energy accumulation and the gradient belt may support seismic shear breakage. Overall, the gravity changes associated with the earthquake preparation indicate a pattern of accelerating increase-decelerating increase-earthquake occurrence. The Songpan-Ganzi block generally displays a negative gravity change, providing evidence for a local upwarp- ing of the deep crust-mantle and an interior expansion of the deep crust attributable to high temperatures. The viewpoint is consistent with the dilatant mechanism for earthquake preparation.

Dynamic changes of a typical linear dune in the Tengger Desert

The dynamical processes of a typical linear dune including morphological features, dune ridge swing range and crest height were investigated at different monitoring periods in the hinterland of Tengger Desert. The results indicated that the development of linear dune depends on not only the northwesterly prevailing wind, but also the winds from northeast and southwest. The dune ridge swayed along its fundamental strike and took on an eastward movement gradually. The original dune strike was NW70° on August 3, 1994, and then changed to NE15° on April 21, 2001. The dune crest increased by 1.8 m longitudinally, which manifested strong wind-blown sand activities in this region. Wind erosion frequently occured at the bottom of sand dune, while sand accumulation appeared on its mid-upper section. The mean wind erosion depth was 25 cm on the bottom of linear dune and the height difference of the control points on the dune’s ridge was 1.13 m. Although the linear dune swayed laterally, the horizontal displacement of its ridge moved eastward 5.8 m averagely. The swing range of the dune crest line is very distinct, with a maximum value of 13.2 m. The highest site on the K-profile swayed on both sides of the dune ridge and the heights were 19.88 m at the control point K5, 19.61 m at K6 and 19.05 m at K7, respectively. The results indicated that the lateral swing of the linear dune was distinct under the northwesterly wind and it moved toward east gradually.

Research on the Dynamic Change of Regional Stress Fields before the M_S8.0 Wenchuan Earthquake

Using the digital telemetric seismic waveform data of Chengdu and Kunming, this article studies the focal mechanism solutions and the apparent stress values of a large number of small earthquakes, and then analyzes the dynamic variation of regional stress fields and the spatio- temporal distribution of apparent stress values. The annual variation values of the azimuth of average principal stress field before the May 12, 2008 Ms8.0 Wenchuan earthquake in the Sichuan-Yunnan region were 58° from 2003 to 2004, 85° from 2003 to 2005,61° from 2006 to 2007 and 90° from 2006 to April 2008 respectively. In recent years, deflection or disturbances occurred in the azimuth of the average principal stress field in the Sichuan-Yunnan region. Analysis shows that this may be related to the change of stress field states of crustal blocks before and after the December 26, 2004 Ms9.0 Sumatra earthquake and the 2008 Ms8.0 Wenchuan earthquake. The ratio of thrust-type earthquakes in the Sichnan-Qinghai block was on the higher side in the period from 2006 to 2007, and the source faulting type of the regional moderate and small earthquakes had changed before the Ms8.0 Wenchnan earthquake. The change of state of the stress field is consistent with the changes in block displacement fields revealed by GPS data and the crustal shortening velocity vertical to the Longmenshan fault zone. Based on the radiation energy calculated from all bands of the seismic waveform, the value of apparent stress σapp is obtained. The fluctuation shape of the fitting trend of the apparent stress is related to the intensity of regional seismicity. It reveals that the micro- dynamic fluctuation process of the regional stress value is similar to the azimuth transition of the regional principal compressive stress field, which can be used to probe for pregnant physical processes. Areas with a higher value of apparent stress σapp are possible areas of potential seismic risk. It can be seen from the spatial distribution of the medium and shortterm apparent stress σapp before the Ms8.0 Wenchuan earthquake, the Longmenshan fault zone is in a low stress distribution area, and the relatively high apparent stress is in the peripheral area. These images may show medium and short-term locking phenomena near the seismogenic tectonics of the Ms8.0 Wenchuan earthquake. For example, changes with time of the focal parameter consistency of the sub-blocks in Sichuan and Yunnan Provinces, continual increase of thrust-type earthquakes in the Sichuan-Qinghai block and the appearance of spatial distribution areas of high apparent σapp stress. The work on this aspect was continued after the Ms8.0 Wenchuan earthquake, and the results seem to be shown a clearer relationship between these phenomena and future great earthquakes.

The impact of dynamic change of cropland on grain production in Jilin

The quantity and quality changes of cropland in Jilin province are analyzed by combining the statistics from 1949 to 1999 and land-use maps interpreted from TM images in 1986 and in 2000. In general, the decreasing trend of the cropland in Jilin province was derived from the statistic data in 1949-1999. While since 1983, the cropland area has increased slightly, because of the conversion from other land-use types to cropland. It is showed that the net increase of cropland was about 43.40×10 4 ha. While the quality change of the cropland can be seen from that mainly caused by the conversion from forestland, grassland to cropland and the change mainly took place in the west, where it is ecologically fragile. According to the spatial distribution model, the centroids' move of the cropland and the grain production are calculated, whose directions are not consistent. The impact of the dynamic change of the cropland on food security is further analyzed.

Dynamic Changes of Lakes in Tibet Plateau and the Climate Interaction in the Past Forty Years

Lake change,as a mirror of climate change,has obvious indication and warning effect on climate.By extracting information of all lakes in Tibet Plateau from Landsat of the 1970’s,the 1990’s,around 2000 and 2010 based on RS and GIS,and,in combination with on-the-spot investigations to a few representative lakes,the authors

Dynamic change of agricultural energy efficiency and its influencing factors in China

In order to practice the concept of‘lucid waters and lush mountains are invaluable assets’and promote the green development of agriculture,it is necessary to improve the efficiency of agricultural energy utilization.Based on the panel data of 28 provinces from 1995 to 2018,this paper calculated China’s agricultural energy input from two categories of direct energy and indirect energy,and used EBM(Epsilon-based Measure)mixed distance function model to measure the energy efficiency of agriculture in China.The nuclear density function and spatial autocorrelation were used to analyze the dynamic evolution of agricultural energy efficiency,and the dynamic panel model was used to analyze the influencing factors of agricultural energy efficiency.The results showed that:①From 1995 to 2018,the total agricultural energy input had increased year by year in China,with an average annual growth rate of 2%.Energy input structure changed from indirect energy-based to direct energy-based.Agricultural energy efficiency showed an evolutionary trend of‘rising-stagnating-rising rapidly’in China.The agricultural energy efficiency was generally low in China,and there was a large space for improvement in agricultural energy efficiency.②From 1995 to 2018,the average annual growth rate of agricultural energy efficiency in the eastern,central and western regions was 2.7%,1.9%and 1.4%respectively.In 2018,the agricultural energy efficiency in the eastern,central and western regions was 0.81,0.71 and 0.59 respectively.The gap between regions was expanding rapidly,and the agricultural energy efficiency in the central and western regions needed to be improved.③From 1995 to 2018,the agricultural energy efficiency of each province was polarized and the absolute gap was widened.There was obvious improvement in agricultural energy efficiency in Guangdong,Shandong,Jiangxi,Jiangsu,Liaoning and Tianjin,while the agricultural energy efficiency of Xinjiang,Guizhou,Zhejiang,Shanghai,and Inner Mongolia deteriorated.④From 1995 to 2018,there was no global spatial correlation of China’s agricultural energy efficiency.However,local‘high-high’concentration gradually appeared in the eastern region since 2010.⑤The first lag of energy efficiency had a significant positive impact on agricultural energy efficiency,and agricultural energy efficiency improvement had a time lag.The level of human capital,per capita net income of farmers and the level of urbanizaton had a significant positive impact on agricultural energy efficiency.The disaster rate,the level of development of secondary and tertiary industries,and the level of opening up had a significant negative impact on agricultural energy efficiency.In the implementation of the strategy of rural revitalization,we should focus on the central and western regions,take the cultivation of professional farmers as the key,focus on improving agricultural production conditions,enhance the level of cooperation between regions,exert the leading role of the secondary and tertiary industries,and enhance the ability of agricultural disaster prevention and mitigation.

Study on dynamic changes of land desertification in the circum-lake zone of the Qinghai Lake in the past 30 years supported by Remote Sensing and Geographical Information System

The circum-lake zone of the Qinghai Lake is one of the most serious regions of desertification on the Qinghai-Tibetan Plateau. Based on Remote Sensing （RS） and Geographical Information System （GIS） techniques, the four sets of remote sensing images acquired in 1976, 1987, 1995, and 2006 were selected to conduct thematic information extraction in 14,300 km2 of land in the circum-lake zone using the Earth Resource Data Analysis System （ERDAS） image and information processing function. In the meantime the off-site interpretation and filed check-correction methods were used to recon- struct the temporal-spatial dynamic changes and differentiation patterns of land desertification in the circum-lake zone in the past 30 years, and based on this, the developmental trend of land desertification in the next 20 years was predicted. The results of the study show that in the past 30 years land desertification in the region experienced a continuous fluctuation between rapid- and slow-development processes in time, while in space it exhibited a few small patchy distributions or sporadic distributions in many places while at the same time, four large sand-dominated distributions stood out and evolved into a circum-lake belt differentiation pattern with a lakeside dike as the connecting line. Due to the integrated effects of climate changes, human activities and artificial rehabilitation, land desertification area in the region in the next 20 years will exhibit an increasing trend in the first 15 years and then increase at a slower rate, and afterward occur in a reverse, decreasing trend.

Dynamic Changes of the CT Perfusion Parameters in the Embolic Model of Cerebral Ischemia

Summary: To study the dynamic changes of CT perfusion parameters during the first 12 h in the embolic cerebral ischemia models. Local cerebral ischemia model were established in 7 New Zealand white rabbits. All CT scans were performed with a GE Lightspeed 16 multislice CT. Following the baseline scan, further CT perfusion scans were performed at the same locations 20 min, 1-6 h and 8, 10 and 12 h after the embolus delivery. Maps of all parameters were obtained by CT perfusion software at each time point. The brains, taken 12 h after the scan, were sliced corresponding to the positions of the CT slices and stained by 2,3,5-triphenyltetrazolium chloride (TTC). On the basis of the TTC results, the ischemic sides were divided into 3 regions: core, penumbra and the relatively normal region. The changes of all parameters were then divided into 3 stages. In the first two hours (the first stage), the CBV dropped more remarkably in the core than in the penumbra but rose slightly in the relatively normal region while the CBF decreased and MTT, TTP extended in all regions to varying degrees. In the 2nd-5th h (the second stage), all the parameters fluctuated slightly around a certain level. In the 5th-12th h (the third stage), the CBV and CBF dropped, and MTT and TTP were prolonged or shortened slightly in the core and penumbra though much notably in the former while the CBV, CBF rose and MTT, TTP were shortened remarkably in the relatively normal region. We experimentally demonstrated that the location and extent of cerebral ischemia could be accurately assessed by CT perfusion imaging. The pathophysiology of the ischemia could be reflected by the CT perfusion to varying degrees.

Dynamic Changes of Microbial Community for Degradation of Lignocellulose

Dynamic changes of a microbial community for lignocellulose degradation were explored in details. Community composition and development were investigated by the means of denaturing gradient gel electrophoresis （DGGE）, and results showed that the microbial community was constituted of 14 kinds of bacteria and presented the fluctuation in some degrees with fermentation. Furthmore, the result of cluster analysis of DGGE pattern was accordant with growth curve, and the degradation process was divided into three stages： initial stage （0-12 h）, intermediate stage （24-144 h） and end stage （144-216 h）.