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Verbal Dyspraxia: A Case Study
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作者 Eirini Konstantopoulou Maria Trapali 《Open Journal of Preventive Medicine》 CAS 2023年第1期1-10,共10页
Introduction: While approaching the aspect of learning disorders, particular attention is paid to verbal dyspraxia, a phenomenon that runs its course regularly over the last years. Verbal dyspraxia is inherent in the ... Introduction: While approaching the aspect of learning disorders, particular attention is paid to verbal dyspraxia, a phenomenon that runs its course regularly over the last years. Verbal dyspraxia is inherent in the person without mental disorders and accompanies them throughout the whole spectrum of life. Comorbidity is an added issue. Although dyspraxia is met in homogeneous groups, some common elements such as intelligence, difficulty regarding linguistic skills, low learning performance and low self-esteem are present. Purpose: The object is to research how dyspraxia is manifested and how it affects a 6-year-old boy as well as the possibility of promptly interfering and simplifying his everyday life. Method: In the current case study, Achenbach’s questionnaire was used, combined with the use of expressive vocabulary. Results: The results of the research were unveiled through experts’ references in coordinance with the conferences conducted. Conclusion: Winding up, dyspraxia is a learning disorder that exists within the person through their lifespan. Immediate diagnosis, combined with experts’ personalized intervention programs (and perhaps, a differentiated curriculum, where applicable) can guide the person to live up to the educational needs. Family’s role is to be supportive, intending to eliminate possible emotional strains. 展开更多
关键词 Learning Disorders Verbal dyspraxia DIAGNOSIS INTERVENTION Case Study
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静宁颗粒对注意力缺陷多动症患儿运动协调障碍的影响 被引量:9
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作者 丁一芸 王雅璇 +2 位作者 任昕昕 方琼杰 王俊宏 《中华中医药学刊》 CAS 北大核心 2018年第4期869-872,共4页
目的:(1)观察注意力缺陷多动障碍(attention deficit hyperactivity disorder,ADHD)患儿是否普遍伴有运动协调障碍;(2)观察静宁颗粒对ADHD患儿典型症状及伴发运动协调障碍的改善情况;(3)探讨ADHD患儿伴运动协调障碍的可能原因... 目的:(1)观察注意力缺陷多动障碍(attention deficit hyperactivity disorder,ADHD)患儿是否普遍伴有运动协调障碍;(2)观察静宁颗粒对ADHD患儿典型症状及伴发运动协调障碍的改善情况;(3)探讨ADHD患儿伴运动协调障碍的可能原因,并推测ADHD可能的发病部位。方法:60例ADHD患儿随机分为托莫西汀组和静宁颗粒组,每组30例,并选择25名健康儿童作为空白对照组。3组研究对象均采用SNAP量表筛查症状并判断其损害程度,同时进行指鼻、指指、对指、翻手试验。结果:60例患儿中,脱落3例,总共完成57例临床观察。正常儿童4项实验结果均显著优于中药组与西药组(P〈0.01)。两治疗组儿童治疗后4项实验结果均优于治疗前(P〈0.05)。结论:多数ADHD患儿伴有运动协调障碍,静宁颗粒对ADHD及其伴发的运动协调障碍有一定的改善作用,推测其作用靶点可能为小脑、大脑-小脑环路的某些相关区域。 展开更多
关键词 注意力缺陷多动障碍 静宁颗粒 运动协调障碍 小脑 大脑-小脑环路
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成年版发育性协调障碍问卷的信效度研究
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作者 袁晓芳 徐青荣 +6 位作者 高小夏 吴野环 郭婧 缪金萍 楼碧文 郭佳琳 张一 《中国康复医学杂志》 CAS CSCD 北大核心 2022年第10期1354-1359,共6页
目的:评估成年版发育性协调障碍问卷(adult developmental co-ordination disorders/dyspraxia checklist,ADC)的效度和信度,为临床推广及应用提供理论依据。方法:对英文版ADC量表进行翻译汉化,招募580例卫生职业学校学生,用汉化后的AD... 目的:评估成年版发育性协调障碍问卷(adult developmental co-ordination disorders/dyspraxia checklist,ADC)的效度和信度,为临床推广及应用提供理论依据。方法:对英文版ADC量表进行翻译汉化,招募580例卫生职业学校学生,用汉化后的ADC量表进行测验,完成填写后统计问卷得分,用内容效度、结构效度、内部一致性信度、分半信度、重测信度对测试结果进行评价。结果:内容效度方面,除A1、B2、B3、B5、B7、B15外,成年版发育性协调障碍问卷各因子与总分的相关系数在0.301—0.60之间(P<0.05),两个分项与总分的相关系数在0.791—0.973之间,具有良好的内容效度;采用验证性因子分析,提取公因子8个,累计方差贡献率为50.97%,各条目在相应因子的因子载荷均>0.5,结构效度良好。成年版发育性协调障碍问卷的Cronbachα系数为0.860,内部一致性信度高,分半信度为0.619,分半信度良好;重测ICC系数0.324—0.909之间,重测信度良好。结论:成年版发育性协调障碍问卷是一份具有良好效度和较好信度的测评工具。ADC可用于发现成年发育性协调障碍(developmental coordination disorder,DCD)疾病及运动协调能力的筛查,也可应用于DCD大规模流行病学调查。 展开更多
关键词 发育性协调障碍问卷 信度 效度 发育性协调障碍
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Foxp2小鼠模型中发育性言语障碍的分子遗传学研究 被引量:1
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作者 李慧 《实验动物与比较医学》 CAS 2019年第4期331-336,共6页
叉头框P2基因(FOXP2)是第一例发现的与一种特异性言语和语言障碍,即发育性言语失用症相关的基因。这一发现开启了研究相关神经通路的崭新方向。FOXP2在各种脊椎动物中显示了序列和神经系统表达的显著高度保守性,例如它在人胎脑中与对等... 叉头框P2基因(FOXP2)是第一例发现的与一种特异性言语和语言障碍,即发育性言语失用症相关的基因。这一发现开启了研究相关神经通路的崭新方向。FOXP2在各种脊椎动物中显示了序列和神经系统表达的显著高度保守性,例如它在人胎脑中与对等阶段的小鼠胎脑中表达模式高度相似。Foxp2小鼠模型包括基因敲除鼠,类似KE家族病理突变的鼠以及Foxp2被人源化的鼠。本文将从分子网络、感觉处理、运动技能学习等三方面综述对Foxp2小鼠模型的研究,以阐明语言障碍的遗传基础。 展开更多
关键词 叉头框P2基因(FOXP2) 发育性言语失用症 Foxp2小鼠模型 神经通路
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Neural Correlates of Developmental Coordination Disorder: The Mirror Neuron System Hypothesis
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作者 Julie M. Werner Sharon A. Cermak Lisa Aziz-Zadeh 《Journal of Behavioral and Brain Science》 2012年第2期258-268,共11页
Primary impairments of developmental coordination disorder (DCD) include impairments in motor skill, motor learning, and imitation. Such difficulties present challenges for individuals with DCD and may persist into ad... Primary impairments of developmental coordination disorder (DCD) include impairments in motor skill, motor learning, and imitation. Such difficulties present challenges for individuals with DCD and may persist into adulthood, negatively impacting daily life in school, work, and social domains. A better understanding of the neural correlates of motor and imitation impairments in DCD holds the potential for informing development of treatment approaches to address these impairments. Although the disorder is assumed to be of neurological origin, little is known of the brain-based etiology of DCD. In recent years the discovery of a fronto-parietal circuit—known as the mirror neuron system—has enabled researchers to better understand imitation, general motor functions, and aspects of social cognition. Given its involvement in imitation and other motor functions, we propose that dysfunction in the mirror neuron system may underlie the characteristic impairments of DCD. We review literature pertaining to the mirror neuron system and develop a theory of disordered mirror neuron functioning in DCD. Finally, we review the limited neuroimaging literature available on neural correlates of DCD and show that the findings from those investigations are congruent with a mirror neuron system theory of DCD. Future research in this population should be designed to investigate specifically mirror neuron regions in individuals with DCD during skilled motor tasks and imitation in particular. 展开更多
关键词 DEVELOPMENTAL Coordination DISORDER dyspraxia IMITATION Mirror NEURON System Motor Learning
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Improvement of Praxis Skills in Children with Hemiplegic Cerebral Palsy by Using New Trend of Augmented Visual and Auditory Feedback Training: A Case Report
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作者 Safaa M. ElKholi Reham S. Alsakhawi 《Open Journal of Therapy and Rehabilitation》 2018年第2期43-55,共13页
Aims: The aim of the study is to investigate if the new method of auditory and visual biofeedback as Upper Limb Exercise may improve praxis skills alone without any traditional physical therapy treatment or not and wi... Aims: The aim of the study is to investigate if the new method of auditory and visual biofeedback as Upper Limb Exercise may improve praxis skills alone without any traditional physical therapy treatment or not and within three successive months of treatment in children with hemiplegic cerebral palsy. Methods: A 6-year-old hemiplegic cerebral palsied child was treated with Upper-Limb Exerciser as one of augmented visual and auditory feedback devices. Sensory Integration and Praxis test was used to measure a child’s ability to integrate sensory input for perception, motor planning, and spatial actions in;Space Visualization, Figure-Ground Perception, Standing and Walking Balance, Design Copying, Postural Praxis, Bilateral Motor Coordination, Constructional Praxis, Postrotary Nystagmus, Motor Accuracy, Sequencing Praxis, Oral Praxis, Manual Form Perception, Kinesthesia, Finger Identification, Graphethesia, Localization of Tactile Stimuli, and Praxis on Verbal Command. Results: The results revealed improvement of the major standard score for each of the 17 subtests of Sensory Integration and Praxis Test when compared after three successive treatment. Conclusion: The using upper limb exerciser as one method of augmented visual and auditory feedback can be used as one of the physical and occupational therapy programs aiming to improve praxis skills in hemiplegic cerebral palsied children. 展开更多
关键词 AUGMENTED VISUAL and Auditory Feedback Cerebral PALSY dyspraxia E-Linked Upper LIMB Exerciser HEMIPLEGIA Sensory Integration and Praxis Test
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点穴疗法治疗缺血性脑卒中后肢体功能障碍的疗效
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作者 刘强 文毅 《大医生》 2018年第8期3-4,共2页
目的探析点穴疗法对缺血性脑卒中患者肢体功能障碍的疗效。方法选取本院收治的80例缺血性脑卒中患者为研究对象,随机分为对照组和实验组,各40例。对照组患者给予内科药物治疗,实验组患者在对照组基础上加用点穴疗法。比较两组患者临床... 目的探析点穴疗法对缺血性脑卒中患者肢体功能障碍的疗效。方法选取本院收治的80例缺血性脑卒中患者为研究对象,随机分为对照组和实验组,各40例。对照组患者给予内科药物治疗,实验组患者在对照组基础上加用点穴疗法。比较两组患者临床疗效、症状改善时间及肢体功能。结果实验组临床总有效率为85.00%,显著高于对照组(62.50%,P <0.05);实验组口眼歪斜、语言謇涩、肢体功能改善时间均显著短于对照组(P <0.05);实验组治疗后肢体功能评分显著高于对照组(P <0.05)。结论应用点穴疗法治疗缺血性脑卒中患者的肢体功能障碍,能够有效减轻患者临床症状,改善患者肢体功能。 展开更多
关键词 缺血性脑卒中 点穴疗法 临床疗效 肢体功能障碍
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丘脑底核深部电刺激对不同性别帕金森病病人生活质量的影响 被引量:2
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作者 江立艳 赵珺燕 +1 位作者 丁毅宏 王晓 《护理研究》 北大核心 2018年第19期3082-3085,共4页
[目的]探讨丘脑底核深部电刺激治疗(STN DBS)对不同性别帕金森病病人生活质量的影响。[方法]术前和术后6个月随访时用帕金森病人生活质量问卷(PDQ-39)和统一帕金森病评定量表(UPDRS)评估病人的生活质量和病情严重程度,比较手术前后和不... [目的]探讨丘脑底核深部电刺激治疗(STN DBS)对不同性别帕金森病病人生活质量的影响。[方法]术前和术后6个月随访时用帕金森病人生活质量问卷(PDQ-39)和统一帕金森病评定量表(UPDRS)评估病人的生活质量和病情严重程度,比较手术前后和不同性别病人得分。[结果]术前,不同性别病人病程和运动功能(UPDRSⅢ)得分差异均无统计学意义;术后,病人运动功能提高且性别间差异无统计学意义;PDQ-39得分显示,仅有女性病人身体活动、病耻感、认知和总得分降低,仅有男性病人身体不适得分降低。[结论]尽管STN DBS对改善病人运动功能方面不存在性别差异,但术后女性病人的生活质量较男性得到更大程度提升。 展开更多
关键词 丘脑底核深部电刺激 帕金森病 生活质量 性别 舒适度 身体活动障碍 病残度
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早产和早期出生与中国城市儿童发育性协调障碍的相关性研究 被引量:5
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作者 刘明霞 花静 +2 位作者 柯李 段雯 杜雯翀 《中国妇幼健康研究》 2022年第3期28-35,共8页
目的调查中国城市儿童早期儿(37~38^(+6)孕周)、晚期早产儿(34~36^(+6)孕周)和中/早期早产儿(<34孕周)发育性协调障碍(DCD)的情况。方法2016年对中国城市3~10岁儿童进行横断面研究,共招募1673名儿童参加运动评估成套测验,分析不同出... 目的调查中国城市儿童早期儿(37~38^(+6)孕周)、晚期早产儿(34~36^(+6)孕周)和中/早期早产儿(<34孕周)发育性协调障碍(DCD)的情况。方法2016年对中国城市3~10岁儿童进行横断面研究,共招募1673名儿童参加运动评估成套测验,分析不同出生胎龄与学龄前和学龄期儿童运动发育的关系。结果调整潜在混杂因素后,学龄前儿童中早期早产儿整体运动能力得分(β=-5.111,95%CI:-9.200~-1.022;P<0.05)和平衡能力得分(β=-5.182,95%CI:-5.055~-1.158;P<0.05)显著低于同龄儿童中的足月儿。调整所有受试者的潜在混杂因素后,所有受试儿童中,中/早期早产儿与足月儿相比出现显著运动障碍的风险更高(OR=2.931,95%CI:1.067~8.054;P<0.05)和学龄前儿童中的中/早期早产儿比足月儿出现DCD风险更高(OR=3.673,95%CI:1.072~12.585;P<0.05)。晚期早产和早期出生对DCD患病无明显影响。结论早产儿DCD患病风险增加,需要针对运动发育进行长期随访和支持性干预。 展开更多
关键词 运动障碍 早产儿 早期儿 儿童 中国
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A Tool for Setting Therapeutic Goals by the Multidisciplinary Team for the Preschool Child With ASD (Autism Spectrum Disorder) 被引量:1
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作者 Kotsopoulou Angelique Georgiou Anastasia Gyftogianni Maria Gyftogianni Kataerina Sakellari Marigo Troupou Antigoni Florou Irene 《Psychology Research》 2014年第5期354-363,共10页
关键词 评估工具 多学科 孩子 自闭 治疗 学龄前 正常发育 临床特点
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Sensorimotor dysfunctions as primary features of autism spectrum disorders 被引量:9
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作者 Matthew W.MOSCONI John A.SWEENEY 《Science China(Life Sciences)》 SCIE CAS CSCD 2015年第10期1016-1023,共8页
Motor impairments in autism spectrum disorders(ASD) have received far less research attention than core social- communication and cognitive features. Yet, behavioral, neurophysiological, neuroimaging and histopatholog... Motor impairments in autism spectrum disorders(ASD) have received far less research attention than core social- communication and cognitive features. Yet, behavioral, neurophysiological, neuroimaging and histopathological studies have documented abnormal motor system development in the majority of individuals with ASD suggesting that these deficits may be primary to the disorder. There are several unique advantages to studying motor development in ASD. First, the neurophysiological substrates of motor skills have been well-characterized via animal and human lesion studies. Second, many of the single-gene disorders associated with ASD also are characterized by motor dysfunctions. Third, recent evidence suggests that the onset of motor dysfunctions may precede the emergence of social and communication deficits during the first year of life in ASD. Motor deficits documented in ASD indicate disruptions throughout the neuroaxis affecting cortex, striatum, the cerebellum and brainstem. Questions remain regarding the timing and development of motor system alterations in ASD, their association with defining clinical features, and their potential for parsing heterogeneity in ASD. Pursuing these questions through neurobiologically informed translational research holds great promise for identifying gene-brain pathways associated with ASD. 展开更多
关键词 AUTISM MOTOR CEREBELLUM dyspraxia OCULOMOTOR
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