Effect of Exogenous Hydrogen Sulfide(H_2S) on the Electrocardiogram(ECG) of Rats Generally Anaesthetized by Zoletil

Hydrogen sulfide （H2S） is the third gaseous signaling molecule discovered in recent years, and plays an important physiological role in the cardivascular system. To explore the effects of different doses of exogenous H2S on the electrocardiogram （ECG） of rats generally anesthetized by zoletil, different doses of NariS solution were used for the intervention of intraperitoneal injection 20 rain before the zoletil anesthesia. The ECGs of rats from each treatment group during the time range of 10^th-50^th min were determined under general anesthesia, and then were compared with those from the control group. The results showed that exogenous H2S could significantly reduce the Q-T interval time limit, thus played a role in slowing tachycardia or arrhythmia and other anomalies, thereby protecting the heart. S-T segment and T segment evaluation values were significantly reduced, which might be associated with bradycardia.

A New Pattern Recognition Method for Detection and Localization of Myocardial Infarction Using T-Wave Integral and Total Integral as Extracted Features from One Cycle of ECG Signal

In this paper we used two new features i.e. T-wave integral and total integral as extracted feature from one cycle of normal and patient ECG signals to detection and localization of myocardial infarction (MI) in left ventricle of heart. In our previous work we used some features of body surface potential map data for this aim. But we know the standard ECG is more popular, so we focused our detection and localization of MI on standard ECG. We use the T-wave integral because this feature is important impression of T-wave in MI. The second feature in this research is total integral of one ECG cycle, because we believe that the MI affects the morphology of the ECG signal which leads to total integral changes. We used some pattern recognition method such as Artificial Neural Network (ANN) to detect and localize the MI, because this method has very good accuracy for classification of normal signal and abnormal signal. We used one type of Radial Basis Function (RBF) that called Probabilistic Neural Network (PNN) because of its nonlinearity property, and used other classifier such as k-Nearest Neighbors (KNN), Multilayer Perceptron (MLP) and Naive Bayes Classification. We used PhysioNet database as our training and test data. We reached over 76% for accuracy in test data for localization and over 94% for detection of MI. Main advantages of our method are simplicity and its good accuracy. Also we can improve the accuracy of classification by adding more features in this method. A simple method based on using only two features which were extracted from standard ECG is presented and has good accuracy in MI localization.

Cardiac arrhythmias detection in an ECG beat signal using fast fourier transform and artificial neural network

Cardiac Arrhythmias shows a condition of abnor-mal electrical activity in the heart which is a threat to humans. This paper presents a method to analyze electrocardiogram (ECG) signal, extract the fea-tures, for the classification of heart beats according to different arrhythmias. Data were obtained from 40 records of the MIT-BIH arrhythmia database (only one lead). Cardiac arrhythmias which are found are Tachycardia, Bradycardia, Supraventricular Tachycardia, Incomplete Bundle Branch Block, Bundle Branch Block, Ventricular Tachycardia. A learning dataset for the neural network was obtained from a twenty records set which were manually classified using MIT-BIH Arrhythmia Database Directory and docu- mentation, taking advantage of the professional experience of a cardiologist. Fast Fourier transforms are used to identify the peaks in the ECG signal and then Neural Networks are applied to identify the diseases. Levenberg Marquardt Back-Propagation algorithm is used to train the network. The results obtained have better efficiency then the previously proposed methods.

Compression of ECG Signal Based on Compressive Sensing and the Extraction of Significant Features

Diagnoses of heart diseases can be done effectively on long term recordings of ECG signals that preserve the signals’ morphologies. In these cases, the volume of the ECG data produced by the monitoring systems grows significantly. To make the mobile healthcare possible, the need for efficient ECG signal compression algorithms to store and/or transmit the signal efficiently has been rising exponentially. Currently, ECG signal is acquired at Nyquist rate or higher, thus introducing redundancies between adjacent heartbeats due to its quasi-periodic structure. Existing compression methods remove these redundancies by achieving compression and facilitate transmission of the patient’s imperative information. Based on the fact that these signals can be approximated by a linear combination of a few coefficients taken from different basis, an alternative new compression scheme based on Compressive Sensing (CS) has been proposed. CS provides a new approach concerned with signal compression and recovery by exploiting the fact that ECG signal can be reconstructed by acquiring a relatively small number of samples in the “sparse” domains through well-developed optimization procedures. In this paper, a single-lead ECG compression method has been proposed based on improving the signal sparisty through the extraction of the signal significant features. The proposed method starts with a preprocessing stage that detects the peaks and periods of the Q, R and S waves of each beat. Then, the QRS-complex for each signal beat is estimated. The estimated QRS-complexes are subtracted from the original ECG signal and the resulting error signal is compressed using the CS technique. Throughout this process, DWT sparsifying dictionaries have been adopted. The performance of the proposed algorithm, in terms of the reconstructed signal quality and compression ratio, is evaluated by adopting DWT spatial domain basis applied to ECG records extracted from the MIT-BIH Arrhythmia Database. The results indicate that average compression ratio of 11:1 with PRD1 = 1.2% are obtained. Moreover, the quality of the retrieved signal is guaranteed and the compression ratio achieved is an improvement over those obtained by previously reported algorithms. Simulation results suggest that CS should be considered as an acceptable methodology for ECG compression.

Early detection of sudden cardiac death by using classical linear techniques and time-frequency methods on electrocardiogram signals

Early detection of sudden cardiac death may be used for surviving the life of cardiac patients. In this paper we have investigated an algorithm to detect and predict sudden cardiac death, by processing of heart rate variability signal through the classical and time-frequency methods. At first, one minute of ECG signals, just before the cardiac death event are extracted and used to compute heart rate variability (HRV) signal. Five features in time domain and four features in frequency domain are extracted from the HRV signal and used as classical linear features. Then the Wigner Ville transform is applied to the HRV signal, and 11 extra features in the time-frequency (TF) domain are obtained. In order to improve the performance of classification, the principal component analysis (PCA) is applied to the obtained features vector. Finally a neural network classifier is applied to the reduced features. The obtained results show that the TF method can classify normal and SCD subjects, more efficiently than the classical methods. A MIT-BIH ECG database was used to evaluate the proposed method. The proposed method was implemented using MLP classifier and had 74.36% and 99.16% correct detection rate (accuracy) for classical features and TF method, respectively. Also, the accuracy of the KNN classifier were 73.87% and 96.04%.

Progress on Fabric Electrodes Used in ECG Signals Monitoring

Wearable monitoring system is designed for skin stimulation of conductive adhesive, prolonged physiological monitoring and biocompatibility, whose core is fabric electrodes and it can feedback physiological status by analysis of abnormal electrocardiogram (ECG). Fabric electrode is a sensor to collect biological signals based on textile materials including signals acquisition, processing systems and information feedback platform and so on. In this paper, the design methods and classification of medical electrodes would be introduced. It also sorted out the principle of biological electrical signals, the design methods and characteristics of different material and different structure electrodes from the point of dry electrodes and wet electrodes. There are many methods that can be used to prepare fabric electrodes. They are mainly metal plating, conductive polymer coating, magnetron sputtering, gas phase deposition and impregnation. Besides, they select the appropriate substrate, conductive medium and composite way to get light fabric electrodes which have high conductivity, good conformability. From the perspective of biological signal acquisition by fabric electrodes, this paper also sorted out the influence and approaches of biological signals and the way to feedback the physiological condition of human. As a new generation of bio-signal acquisition material, fabric electrode has met the requirements of the development of modern medicine. Fabric electrode is different from traditional conductive materials in the characteristics of comfort, intelligence, convenience, accuracy and so on.

Individual Identification Using ECG SignalsW

The electrocardiogram (ECG) signal used for diagnosis and patient monitoring, has recently emerged as a biometric recognition tool. Indeed, ECG signal changes from one person to another according to health status, heart geometry and anatomy among other factors. This paper forms a comparative study between different identification techniques and their performances. Previous works in this field referred to methodologies implementing either set of fiducial or set non-fiducial features. In this study we show a comparison of the same data using a fiducial feature set and a non-fiducial feature set based on statistical calculation of wavelet coefficient. High identification rates were measured in both cases, non-fiducial using Discrete Meyer (dmey) wavelet outperformed the rest at 98.65.

ANALYSIS OF AFFECTIVE ECG SIGNALS TOWARD EMOTION RECOGNITION

Recently,as recognizing emotion has been one of the hallmarks of affective computing,more attention has been paid to physiological signals for emotion recognition.This paper presented an approach to emotion recognition using ElectroCardioGraphy(ECG) signals from multiple subjects.To collect reliable affective ECG data,we applied an arousal method by movie clips to make subjects experience specific emotions without external interference.Through precise location of P-QRS-T wave by continuous wavelet transform,an amount of ECG features was extracted sufficiently.Since feature selection is a combination optimization problem,Improved Binary Particle Swarm Optimization(IBPSO) based on neighborhood search was applied to search out effective features to improve classification results of emotion states with the help of fisher or K-Nearest Neighbor(KNN) classifier.In the experiment,it is shown that the approach is successful and the effective features got from ECG signals can express emotion states excellently.

Preliminary Biometrics of ECG Signal Based on Temporal Organization through the Implementation of a Multilayer Perceptron Neural Network

The attributes of the ECG signal signifying the unique electrical properties of the heart offer the opportunity to expand the realm of biometrics, which pertains the identification of an individual based on physical characteristics. The temporal organization of the ECG signal offers a basis for composing a machine learning feature set. The four attributes of the feature set are derived through software automation enabled by Python. These four attributes are the temporal differential of the P wave maximum and T wave maximum relative to the R wave maximum and the Q wave minimum and S wave minimum relative to the R wave maximum. The multilayer perceptron neural network was applied and evaluated in terms of classification accuracy and time to develop the model. Superior performance was achieved with respect to a reduced feature set considering only the temporal differential of the P wave maximum and T wave maximum relative to the R wave maximum by comparison to all four attributes applied to the feature set and the temporal differential of the Q wave minimum and S wave minimum relative to the R wave maximum. With these preliminary findings and the advent of portable and wearable devices for the acquisition of the ECG signal, the temporal organization of the ECG signal offers robust potential for the field of biometrics.

Application of Holter ECG Signal Analysis Based on Wavelet and Data Mining Technique

A new model based on dyadic differential wavelet was developed for detecting the R peak in Holter ECG signal according to the design of data mining. The Mallat recursive filter algorithm was introduced to calculate wavelet and optimize the detection algorithm which is based on the equivalent filter technique. The detection algorithm has been verified by MIT arrhythmia database with a high efficiency of 99%. After optimization, the algorithm was put into clinical experiment and tested in the Air Force Hospital in Tianjin for about two months. After about 108 hearts beating test of more than 100 patients, the total efficient detection rate has reached 97%. Now this algorithm module has been applied in business software and shows perfect performance under the complex conditions such as the inversion of heart beating, the falling off of the electrodes, the excursion of base line and so on.

Detection of healthy and pathological heartbeat dynamics in ECG signals using multivariate recurrence networks with multiple scale factors

The electrocardiogram(ECG)is one of the physiological signals applied in medical clinics to determine health status.The physiological complexity of the cardiac system is related to age,disease,etc.For the investigation of the effects of age and cardiovascular disease on the cardiac system,we then construct multivariate recurrence networks with multiple scale factors from multivariate time series.We propose a new concept of cross-clustering coefficient entropy to construct a weighted network,and calculate the average weighted path length and the graph energy of the weighted network to quantitatively probe the topological properties.The obtained results suggest that these two network measures show distinct changes between different subjects.This is because,with aging or cardiovascular disease,a reduction in the conductivity or structural changes in the myocardium of the heart contributes to a reduction in the complexity of the cardiac system.Consequently,the complexity of the cardiac system is reduced.After that,the support vector machine(SVM)classifier is adopted to evaluate the performance of the proposed approach.Accuracy of 94.1%and 95.58%between healthy and myocardial infarction is achieved on two datasets.Therefore,this method can be adopted for the development of a noninvasive and low-cost clinical prognostic system to identify heart-related diseases and detect hidden state changes in the cardiac system.

Detection of T-wave Alternans in ECG Signals Using FRFT and Tensor Decomposition

T-wave alternans(TWA)refers to the periodic beat-to-beat variation in the amplitude of T-wave in the electrocardiogram(ECG)signal in an ABAB-pattern.TWA has been proven to be a very important indicator of malignant arrhythmia risk stratification.A new method to detect TWA by combining fractional Fourier transform(FRFT)and tensor decomposition is proposed.First,the T-wave vector is extracted from the ECG of each heartbeat,and its FRFT amplitudes at multiple orders are arranged to form a T-wave matrix.Then,a third-order tensor is composed of T-wave matrices of several consecutive heart beats.After tensor decomposition,projection matrices are obtained in three dimensions.The complexity of the projection matrix is measured by Shannon entropy to obtain feature vector to detect the presence of TWA.Results show that the sensitivity,specificity,and accuracy of the algorithm on the MIT-BIH database are 91.16%,94.25%,and 92.68%,respectively.This method effectively utilizes the fractional domain information of ECG,and shows the promising potential of the FRFT in ECG signal processing.

基于单通道ECG信号与INFO-ABCLogitBoost模型的睡眠分期

为了减少对传统多导睡眠图(PSG)系统的依赖,基于单通道心电图(ECG)信号,设计了一种简单高效的睡眠分析算法.采用最大重叠离散小波变换(MODWT)对原始信号进行多分辨分析,再进一步提取峰值信息;根据峰值位置的一阶偏差,提取多维度的心率变异性(HRV)特征.为了进一步筛选与不同睡眠阶段具有强关联性的HRV特征,提出基于ReliefF算法与Gini指数的特征提取方法.在此基础上,采用INFO-ABCLogitBoost方法挖掘HRV与不同睡眠阶段之间的关联性,从而实现睡眠阶段的精细分类.在实际公开数据集上的实验结果表明,所提出的模型在睡眠分期任务中,总体精度为83.67%,准确率为82.59%,Kappa系数为77.94%,F1-Score为82.97%.相比于睡眠分期任务中的常规模型,所提方法展现出更加高效便捷的睡眠质量评估性能,有助于实现家庭或移动医疗场景下的睡眠监测.

Automated Deep Learning Based Cardiovascular Disease Diagnosis Using ECG Signals

Automated biomedical signal processing becomes an essential process to determine the indicators of diseased states.At the same time,latest develop-ments of artificial intelligence(AI)techniques have the ability to manage and ana-lyzing massive amounts of biomedical datasets results in clinical decisions and real time applications.They can be employed for medical imaging;however,the 1D biomedical signal recognition process is still needing to be improved.Electrocardiogram(ECG)is one of the widely used 1-dimensional biomedical sig-nals,which is used to diagnose cardiovascular diseases.Computer assisted diag-nostic modelsfind it difficult to automatically classify the 1D ECG signals owing to time-varying dynamics and diverse profiles of ECG signals.To resolve these issues,this study designs automated deep learning based 1D biomedical ECG sig-nal recognition for cardiovascular disease diagnosis(DLECG-CVD)model.The DLECG-CVD model involves different stages of operations such as pre-proces-sing,feature extraction,hyperparameter tuning,and classification.At the initial stage,data pre-processing takes place to convert the ECG report to valuable data and transform it into a compatible format for further processing.In addition,deep belief network(DBN)model is applied to derive a set of feature vectors.Besides,improved swallow swarm optimization(ISSO)algorithm is used for the hyper-parameter tuning of the DBN model.Lastly,extreme gradient boosting(XGBoost)classifier is employed to allocate proper class labels to the test ECG signals.In order to verify the improved diagnostic performance of the DLECG-CVD model,a set of simulations is carried out on the benchmark PTB-XL dataset.A detailed comparative study highlighted the betterment of the DLECG-CVD model interms of accuracy,sensitivity,specificity,kappa,Mathew correlation coefficient,and Hamming loss.

Visualization of the Machine Learning Process Using J48 Decision Tree for Biometrics through ECG Signal

The inherently unique qualities of the heart infer the candidacy for the domain of biometrics, which applies physiological attributes to establish the recognition of a person’s identity. The heart’s characteristics can be ascertained by recording the electrical signal activity of the heart through the acquisition of an electrocardiogram (ECG). With the application of machine learning the subject specific ECG signal can be differentiated. However, the process of distinguishing subjects through machine learning may be considered esoteric, especially for contributing subject matter experts external to the domain of machine learning. A resolution to this dilemma is the application of the J48 decision tree available through the Waikato Environment for Knowledge Analysis (WEKA). The J48 decision tree elucidates the machine learning process through a visualized decision tree that attains classification accuracy through the application of thresholds applied to the numeric attributes of the feature set. Additionally, the numeric attributes of the feature set for the application of the J48 decision tree are derived from the temporal organization of the ECG signal maxima and minima for the respective P, Q, R, S, and T waves. The J48 decision tree achieves considerable classification accuracy for the distinction of subjects based on their ECG signal, for which the machine learning model is briskly composed.

Intelligent Biomedical Electrocardiogram Signal Processing for Cardiovascular Disease Diagnosis

Automatic biomedical signal recognition is an important processfor several disease diagnoses. Particularly, Electrocardiogram (ECG) is commonly used to identify cardiovascular diseases. The professionals can determine the existence of cardiovascular diseases using the morphological patternsof the ECG signals. In order to raise the diagnostic accuracy and reduce thediagnostic time, automated computer aided diagnosis model is necessary. Withthe advancements of artificial intelligence (AI) techniques, large quantity ofbiomedical datasets can be easily examined for decision making. In this aspect,this paper presents an intelligent biomedical ECG signal processing (IBECGSP) technique for CVD diagnosis. The proposed IBECG-SP technique examines the ECG signals for decision making. In addition, gated recurrent unit(GRU) model is used for the feature extraction of the ECG signals. Moreover,earthworm optimization (EWO) algorithm is utilized to optimally tune thehyperparameters of the GRU model. Lastly, softmax classifier is employedto allot appropriate class labels to the applied ECG signals. For examiningthe enhanced outcomes of the proposed IBECG-SP technique, an extensivesimulation analysis take place on the PTB-XL database. The experimentalresults portrayed the supremacy of the IBECG-SP technique over the recentstate of art techniques.

Compression of ECG Signals Based on DWT and Exploiting the Correlation between ECG Signal Samples

This paper presents a hybrid technique for the compression of ECG signals based on DWT and exploiting the correlation between signal samples. It incorporates Discrete Wavelet Transform (DWT), Differential Pulse Code Modulation (DPCM), and run-length coding techniques for the compression of different parts of the signal;where lossless compression is adopted in clinically relevant parts and lossy compression is used in those parts that are not clinically relevant. The proposed compression algorithm begins by segmenting the ECG signal into its main components (P-waves, QRS-complexes, T-waves, U-waves and the isoelectric waves). The resulting waves are grouped into Region of Interest (RoI) and Non Region of Interest (NonRoI) parts. Consequently, lossless and lossy compression schemes are applied to the RoI and NonRoI parts respectively. Ideally we would like to compress the signal losslessly, but in many applications this is not an option. Thus, given a fixed bit budget, it makes sense to spend more bits to represent those parts of the signal that belong to a specific RoI and, thus, reconstruct them with higher fidelity, while allowing other parts to suffer larger distortion. For this purpose, the correlation between the successive samples of the RoI part is utilized by adopting DPCM approach. However the NonRoI part is compressed using DWT, thresholding and coding techniques. The wavelet transformation is used for concentrating the signal energy into a small number of transform coefficients. Compression is then achieved by selecting a subset of the most relevant coefficients which afterwards are efficiently coded. Illustrative examples are given to demonstrate thresholding based on energy packing efficiency strategy, coding of DWT coefficients and data packetizing. The performance of the proposed algorithm is tested in terms of the compression ratio and the PRD distortion metrics for the compression of 10 seconds of data extracted from records 100 and 117 of MIT-BIH database. The obtained results revealed that the proposed technique possesses higher compression ratios and lower PRD compared to the other wavelet transformation techniques. The principal advantages of the proposed approach are: 1) the deployment of different compression schemes to compress different ECG parts to reduce the correlation between consecutive signal samples;and 2) getting high compression ratios with acceptable reconstruction signal quality compared to the recently published results.

Classification of Electrocardiogram Signals for Arrhythmia Detection Using Convolutional Neural Network

With the help of computer-aided diagnostic systems,cardiovascular diseases can be identified timely manner to minimize the mortality rate of patients suffering from cardiac disease.However,the early diagnosis of cardiac arrhythmia is one of the most challenging tasks.The manual analysis of electrocardiogram(ECG)data with the help of the Holter monitor is challenging.Currently,the Convolutional Neural Network(CNN)is receiving considerable attention from researchers for automatically identifying ECG signals.This paper proposes a 9-layer-based CNN model to classify the ECG signals into five primary categories according to the American National Standards Institute(ANSI)standards and the Association for the Advancement of Medical Instruments(AAMI).The Massachusetts Institute of Technology-Beth Israel Hospital(MIT-BIH)arrhythmia dataset is used for the experiment.The proposed model outperformed the previous model in terms of accuracy and achieved a sensitivity of 99.0%and a positivity predictively 99.2%in the detection of a Ventricular Ectopic Beat(VEB).Moreover,it also gained a sensitivity of 99.0%and positivity predictively of 99.2%for the detection of a supraventricular ectopic beat(SVEB).The overall accuracy of the proposed model is 99.68%.

Improved Bat Algorithm with Deep Learning-Based Biomedical ECG Signal Classification Model

With new developments experienced in Internet of Things(IoT),wearable,and sensing technology,the value of healthcare services has enhanced.This evolution has brought significant changes from conventional medicine-based healthcare to real-time observation-based healthcare.Biomedical Electrocardiogram(ECG)signals are generally utilized in examination and diagnosis of Cardiovascular Diseases(CVDs)since it is quick and non-invasive in nature.Due to increasing number of patients in recent years,the classifier efficiency gets reduced due to high variances observed in ECG signal patterns obtained from patients.In such scenario computer-assisted automated diagnostic tools are important for classification of ECG signals.The current study devises an Improved Bat Algorithm with Deep Learning Based Biomedical ECGSignal Classification(IBADL-BECGC)approach.To accomplish this,the proposed IBADL-BECGC model initially pre-processes the input signals.Besides,IBADL-BECGC model applies NasNet model to derive the features from test ECG signals.In addition,Improved Bat Algorithm(IBA)is employed to optimally fine-tune the hyperparameters related to NasNet approach.Finally,Extreme Learning Machine(ELM)classification algorithm is executed to perform ECG classification method.The presented IBADL-BECGC model was experimentally validated utilizing benchmark dataset.The comparison study outcomes established the improved performance of IBADL-BECGC model over other existing methodologies since the former achieved a maximum accuracy of 97.49%.

Secured Transmission of ECG Signals: Numerical and Electronic Simulations

In many domains of science and technology, as the need for secured transmission of information has grown over the years, a variety of methods have been studied and devised to achieve this goal. In this paper, we present an information securing method using chaos encryption. Our proposal uses only one chaotic oscillator both for signal encryption and decryption for?avoiding the delicate synchronisation step. We carried out numerical and electronic simulations of the proposed circuit using electrocardiographic signals as input. Results obtained from both simulations were compared and exhibited a good agreement proving the suitability of our system for signal encryption and decryption.