The purpose of this study was to explore the different effects between biomimetic mineralized collagen(MC)and ordinary physically blended hydroxyapatite/collagen(HA/Col)composite in evaluating new bone formation and r...The purpose of this study was to explore the different effects between biomimetic mineralized collagen(MC)and ordinary physically blended hydroxyapatite/collagen(HA/Col)composite in evaluating new bone formation and regenerated bone height in human extraction sockets.Thirty-four patients who cannot retain teeth caused by trauma or decay were randomly selected from Department of Stomatology of Dongzhimen Hospital from December 2013 to December 2014.The patients were randomly divided into two groups.After the operation of tooth extraction,17 patients were implanted with biomimetic MC(MC group),and other 17 patients were implanted with ordinary physically blended nHA/Col composite(nHA/Col group).X-ray positioning projection by auto-photographing was taken to test the distance between the lowest position and the neighboring CEJm-CEJd immediately,1 month and 3 months after the operation.The height of new bone formation of the MC group was significantly higher than the nHA/Col group.Biomimetic MC showed better clinical outcomes in the bone formation for extraction site preservation and would have broad application prospect in the field of oral and maxillofacial surgeries.展开更多
The purpose of this study was to demonstrate the feasibility of applying cone-beam computed tomography（CBCT） to observe dimensional changes in human alveolar bone continuously after tooth extraction.Sixty patients w...The purpose of this study was to demonstrate the feasibility of applying cone-beam computed tomography（CBCT） to observe dimensional changes in human alveolar bone continuously after tooth extraction.Sixty patients were selected from a CBCT database.Each patient had two CBCT scans（CBCT I and CBCT II）,one taken before and one taken after implant surgery.A fixed anatomic reference point was used to orient the horizontal slice of the two scans.The alveolar ridge width was measured on the horizontal slice.In each series of CBCT I sagittal slices,the number of slices from the start point to the pulp center of the test tooth was recorded.The tooth length was measured on the sagittal slice.In each series of CBCT II slices,tooth length was measured on a sagittal slice selected based on the number of slices from the start point to the pulp center recorded in CBCT I.Intraobserver reliability,assessed by the intraclass correlation coefficient（ICC）,was high.Paired sample t-tests of repeated measurements of both tooth length and alveolar bone width showed no statistically significant differences（P0.05）.This study has proved that projection differences among CBCT scans taken at different time points from one patient can be neglected without affecting the accuracy of millimeter scale measurements.CBCT is a reliable imaging tool for continuously observing dimensional changes in human alveolar bone.展开更多
基金supported by the National Basic Research Program of China(973 Program,2011CB606205)the‘Twelfth Five-Year’National Science and Technology Support Program(2012BAI17B02)the Ministry of Science and Technology of China and the National Natural Science Foundation of China(Grant Nos.21371106 and 51402167).
文摘The purpose of this study was to explore the different effects between biomimetic mineralized collagen(MC)and ordinary physically blended hydroxyapatite/collagen(HA/Col)composite in evaluating new bone formation and regenerated bone height in human extraction sockets.Thirty-four patients who cannot retain teeth caused by trauma or decay were randomly selected from Department of Stomatology of Dongzhimen Hospital from December 2013 to December 2014.The patients were randomly divided into two groups.After the operation of tooth extraction,17 patients were implanted with biomimetic MC(MC group),and other 17 patients were implanted with ordinary physically blended nHA/Col composite(nHA/Col group).X-ray positioning projection by auto-photographing was taken to test the distance between the lowest position and the neighboring CEJm-CEJd immediately,1 month and 3 months after the operation.The height of new bone formation of the MC group was significantly higher than the nHA/Col group.Biomimetic MC showed better clinical outcomes in the bone formation for extraction site preservation and would have broad application prospect in the field of oral and maxillofacial surgeries.
基金supported by the National Natural Science Foundation of China(No.81371115)
文摘The purpose of this study was to demonstrate the feasibility of applying cone-beam computed tomography（CBCT） to observe dimensional changes in human alveolar bone continuously after tooth extraction.Sixty patients were selected from a CBCT database.Each patient had two CBCT scans（CBCT I and CBCT II）,one taken before and one taken after implant surgery.A fixed anatomic reference point was used to orient the horizontal slice of the two scans.The alveolar ridge width was measured on the horizontal slice.In each series of CBCT I sagittal slices,the number of slices from the start point to the pulp center of the test tooth was recorded.The tooth length was measured on the sagittal slice.In each series of CBCT II slices,tooth length was measured on a sagittal slice selected based on the number of slices from the start point to the pulp center recorded in CBCT I.Intraobserver reliability,assessed by the intraclass correlation coefficient（ICC）,was high.Paired sample t-tests of repeated measurements of both tooth length and alveolar bone width showed no statistically significant differences（P0.05）.This study has proved that projection differences among CBCT scans taken at different time points from one patient can be neglected without affecting the accuracy of millimeter scale measurements.CBCT is a reliable imaging tool for continuously observing dimensional changes in human alveolar bone.
