The Relationship between Self-Esteem and Social Phobia among College Students:The Mediating Effect of Fear of Negative Evaluation and the Moderating Effect of Perfectionism

Objectives:To explore the relationship between college students’self-esteem(SE)and their social phobia(SP),as well as the mediating role of fear of negative evaluation(FNE)and the moderating effect of perfectionism.Methods:A convenience sampling survey was carried out for 1020 college students from Shandong Province of China,utilizing measures of college students’self-esteem,fear of negative evaluation,perfectionism,and social phobia.Data analysis was performed using the SPSS PROCESS macro.Results:(1)college students’self-esteem significantly and negatively predicts their social phobia(β=−0.31,t=−10.10,p<0.001);(2)fear of negative evaluation partially mediates the relation between self-esteem and social phobia among college students,with the mediating effect accounting for 48.97%of the total effect(TE);(3)the mediating role of fear of negative evaluation is moderated by perfectionism(β=0.18,t=7.75,p<0.001),where higher levels of perfectionism strengthen the mediating effect of fear of negative evaluation.Conclusions:Perfectionism moderates the mediating effect that fear of negative evaluation plays,establishing a moderated mediating model.

Resilience provides mediating effect of resilience between fear of progression and sleep quality in patients with hematological malignancies

BACKGROUND Hematological tumors are common malignant tumors,with high morbidity and mortality rates.Most patients with hematological malignancies develop sleep disorders that seriously affect their life and health because of acute onset of disease,rapid progression,high recurrence rates,complex treatment methods,and treatment costs.AIM To explore the mediating effect of resilience on fear of disease progression and sleep quality in patients with hematological malignancies.METHODS A cross-sectional analysis of 100 patients with hematological malignancies,treated in the First Affiliated Hospital of Jinzhou Medical University between August 2022 and August 2023,was conducted.Patients were assessed using a general data survey,a simplified scale for the fear of progression(FoP)of disease,a resilience scale,and the Pittsburgh Sleep Quality Index.Statistical analysis was conducted to determine the relationship between various patient characteristics and FoP,resilience,and sleep quality.Spearman’s correlation analysis was used to examine the correlations between mental resilience,FoP,and sleep quality.RESULTS The total FoP score mean value in patients with hematological malignancies was 38.09±5.16;the total resilience score mean value was 40.73±7.04;and the Pittsburgh Sleep Quality Index score mean value was 10.72±1.90.FoP,resilience,and sleep quality of the patients were associated with family per capita monthly income and patient education level(P<0.05).Spearman correlation analysis revealed that FoP was negatively correlated with resilience and sleep quality scores(r=-0.560,-0.537,P<0.01),respectively,and resilience was significantly associated with sleep quality scores(r=0.688,P<0.01).Mediation analysis showed that the mediating effect of resilience between FoP and sleep quality in patients with hematological malignancies was-0.100 and accounted for 50.51%of the total effect.This indicated that FoP directly and indirectly affected sleep quality through the mesomeric effect of resilience.CONCLUSION Resilience is an intermediary variable between FoP and sleep quality in patients with hematological malignancies.Medical staff should evaluate and follow-up FoP and resilience to implement measures to improve sleep quality.

Correlation among anxiety and depression,fear of disease progression,and social support in coronary heart disease

BACKGROUND The mental well-being of individuals with coronary heart disease(CHD)during the intensive care unit(ICU)transition period is a multifaceted and significant concern.In this phase,the individuals might encounter psychological challenges like anxiety and depression,which can impede their recuperation and potentially have lasting effects on their health.AIM To investigate the correlation among psychological factors in CHD patients in the ICU transition period.METHODS A questionnaire survey was conducted with 119 patients admitted to the ICU after coronary artery bypass grafting between March and December 2023.Variations in Hamilton Anxiety Scale(HAMA)and Hamilton Depression Scale(HAMD),Fear of Progression Questionnaire-Short Form(Fop-Q-SF),and Social Support Rating Scale(SSRS)were collected and analyzed among diverse populations.We used Pearson’s correlation analysis to examine the correlation.Multiple linear regression analysis was used to explore whether these indicators influenced depression and anxiety in the patients.RESULTS The total scores for anxiety,depression,fear of disease progression,and social support were(7.50±1.41)points,(8.38±1.62)points,(35.19±8.14)points,and(36.34±7.08)points,respectively(P<0.05).Multivariate regression analysis showed that both the level of disease progression and social support affected the level of postoperative depression and anxiety in patients.CONCLUSION The anxiety and depression levels were positively related to each dimension of phobia disease progression and negatively related to each dimension of social support among patients with CHD.

The Association between Fear of COVID-19,Obsession with COVID-19,and Post Traumatic Stress Disorder in Korean Emergency Rescue Firefighters:A Cross-Sectional Study

During the rapid spread of COVID-19,first responders are at risk of being exposed to COVID-19 due to their role in providing first aid and responding to an unspecified number of people.This uncertainty can have adverse mental health effects,such as increased anxiety and fear.This study aimed to investigate the degree of association between fear of COVID-19,obsession with COVID-19,and post-traumatic stress disorder(PTSD)in emergency rescue firefighters.The participants were 150 emergency rescue firefighters working in Region S,Korea.They filled out self-report questionnaires:The data obtained through the Fear of COVID-19 Scale,Obsession with COVID-19 Scale,and Impact of Event Scale-Revised Korean version were subjected to nonparametric statistical analysis using SPSS WIN 25.0.The study found a significant correlation between emergency rescue firefighters’fear of COVID-19,obsession with COVID-19,and PTSD.Fear and obsession with COVID-19 were higher among first responder firefighters who were directly involved in COVID-19-related tasks.Furthermore,a one-point increase in obsession was associated with a 2.837-point increase in PTSD.Based on the results,we found that there is a need for effective control of obsessions and fears among first responder firefighters during COVID-19,and we suggest that there is a need for mental health care for first responder firefighters during the pandemic through the development and support of programs to prevent and mitigate obsessions.

Research Status of Fear of Cancer Recurrence in Breast Cancer Patients

Fear of disease progression is one of the most common psychological problems in the treatment of cancer patients. Early recognition and intervention can effectively control the level of fear of disease progression and improve the quality of life of patients. The present situation and influencing factors of FoP in breast cancer patients were reviewed in this paper, in order to provide reference for clinical research of breast cancer patients.

Qualitative Analysis of a Diffusive Predator-prey Model with Nonlcoal Fear Effect

In this paper,we establish a delayed predator-prey model with nonlocal fear effect.Firstly,the existence,uniqueness,and persistence of solutions of the model are studied.Then,the local stability,Turing bifurcation,and Hopf bifurcation of the constant equilibrium state are analyzed by examining the characteristic equation.The global asymptotic stability of the positive equilibrium point is investigated using the Lyapunov function method.Finally,the correctness of the theoretical analysis results is verified through numerical simulations.

Dynamical Behaviors of a Modified Leslie-Gower Predator-Prey System with Fear Effect and Prey Refuge

In this paper, the dynamical behaviors of a modified Leslie-Gower predator-prey model incorporating fear effect and prey refuge are investigated. We delve into the construction of the model and its biological significance, with preliminary results encompassing positivity, boundedness, and persistence. The stability of the system’s boundary and positive equilibrium points is proven by calculating the real part of the eigenvalues of the Jacobian matrix. At the positive equilibrium point, we demonstrate that the system’s unique positive equilibrium is globally asymptotically stable by using the Dulac criterion. Furthermore, at this equilibrium point, we employ the Implicit Function Theorem to discuss how fear effects and prey refuges influence the population densities of both prey and predators. Finally, numerical simulations are conducted to validate the above-mentioned conclusions and explored the impact of Predator-taxis sensitivity αon dynamics of the system.

Muscle Strength, Lumbar Curve, Fear of Movement and Functional Disability among Patients with Lumbar Disc Herniation: A Review

Introduction: Lumbar disc herniation (LDH) refers to the rupture of the fibrous annulus of the intervertebral discs. Lumbar curvature may lead to the occurrence of lumbar disc degeneration. Fear of movement may worsen their disc herniation and cause further pain and injury. LDH conditions impact the individuals’ quality of life, to explore the relationship between lumbar curve, muscle strength, fear of movement and functional disability among patients with LDH. Methods: An electronic search was conducted on PubMed, Medline, Science Direct, Springerlink, Google Scholar and a hand search from reference lists was reviewed. Publications were included in human studies, patients 25 - 85 years of age, original studies and published in English language journals from January 2002 to December 2023. Result: In total, 64 articles were researched through the online search engines, and 9 papers were found through manual searches of reference lists. As a result, a total of 11 articles were included for the purpose of this review. The comprehensive analysis revealed the presence of eight cross-sectional studies, two retrospective studies and one experimental study. A minimum of 25 participants and a maximum of 360 participants were included. Ten studies included both genders, only one studies included healthy adults and patients with LDH but these studies didn’t mention gender. Results showed that the factors influencing LDH can be categorized into non-modifiable factors, such as gender, age, height or others. Modifiable factors included increased BMI, DM, smoking, alcohol, employment status, lifestyle and health problems or psychology. Conclusion: Females with greater VASC may be at risk of LDH. The lumbar extensor muscles indicated a localized disc herniation or nerve root pathology in patients with LDH. The fear of movement may lead to psychological consequences and reduce functional disability among patients with LDH.

Coping review of dementia fear studies among middle-aged and elderly people in the community

This study used Arksey and O’Malley’s scoping review methodology as a framework and searched the following databases:PubMed,Embase,EBSCO,CINAHL,Web of Science,Cochrane Library,Scopus,CNKI,Wanfang,VIP,and the Chinese Biomedical Literature Database.The database is open to December 20,2023,and documents related to the fear of dementia among the elderly in the community are described and analyzed to provide a reference for future research in this field.At the same time,we screened,extracted,and summarized relevant information from 21 included documents(16 in English and 5 in Chinese),which consisted of 16 cross-sectional studies,2 quasi-experimental studies,2 randomized controlled studies,and 1 longitudinal study.Sixteen of the included documents mentioned the incidence or level of dementia fear among the elderly in the community,2 addressed the adverse effects of dementia fear,and 4 reported prevention and intervention measures for dementia fear.In total,there are 8 assessment tools,and the influencing factors are categorized into sociodemographic characteristics,psychological and behavioral characteristics,sociocultural background factors,and health and dementia-related factors.The final conclusion is that the fear of dementia is common among the elderly in the community.In the future,the application of research tools should be expanded among middle-aged individuals,with considerations for other types of dementia in mind.It is recommended to conduct large-scale,multi-center randomized controlled trials while confirming the intervention’s effect on different types of middle-aged and elderly individuals,focusing on the long-term impact of these intervention measures to promote healthy aging.

The Mediating Role of Religious Beliefs in the Relationship between Well-Being and Fear of the Pandemic

Religion is one of the social entities that has had a significant impact on the pandemic.The study’s goals are to investigate the relationship between well-being and fear of COVID-19,as well as to test whether religious beliefs mediate the effect of wellbeing on fear of COVID-19.The sample comprised of 433 participants in Vietnam.Independent Sample t-Test,One-way ANOVA,mediation analysis were used to analyze the data.In the levels of well-being,individuals who engage in religious services daily have higher levels than those hardly and never attend,and people from the age of 18 to 30 have higher levels than individuals from 31 to above 60 years.In addition,people aged from 51 to above 60 have higher levels of religious beliefs than people aged from 18 to 50.Females experience more fear of COVID-19 compared to males.The latter illustrates that religious beliefs mediate the effect of well-being on fear of COVID-19.Social workers and clinicians must prioritize older adults and people with chronic diseases for early mental interventions,and they should be aware of the role of religion in psychological treatment integration.

Influencing factors of fear of falling among glaucoma patients in west China:a cross-sectional study

AIM:To investigate the current situation and influencing factors of fear of falling in glaucoma patients in western China.METHODS:In this cross-sectional study,glaucoma patients treated in the Ophthalmology Department of West China Hospital of Sichuan University were conducted to investigate the demographic data,visual acuity,visual field,activities of daily living,risk of falling,fear of falling and psychological states.Generalized linear model was used for multivariate analysis with fear of falling as dependent variable and other factors as independent variables.RESULTS:The mean score of the Chinese version modified Fall Efficacy Scale(MFES)was 7.52±2.09 points.Univariate analysis and multivariate analysis showed that the history of falls within one year,visual acuity,visual field,risk of falling,activities of daily living and psychological states had statistically difference on fear of falling(P<0.05).CONCLUSION:Glaucoma patients in west China have relatively high risk of fear of falling.History of falling within 1y,severe visual function impairment,high risk of falling,incapable of independence of daily living,and abnormal psychological state are risk factors of fear of falling among glaucoma patients.

COVID-19 Vaccine Rejection among Muslims in Turkey: Religiosity and Fear of Death

This study aimed to examine the relationship between COVID-19 vaccine refusal and religiosity and fear of death among Muslims living in Turkey. This cross-sectional study was conducted online with 1046 adults aged 18 and older. The Ok-Religious Attitude Scale (Islam) (ORASI) (8 items) and Thorson-Powell Death Anxiety Scale (TPDAS) (20 items) were used as data collection instruments. The data were analyzed using the Pearson chi-square test, Student’s t-test, and binary logistic regression. A p-value of 0.05). In binary logistic regression analysis, vaccine rejection was 7.19 times higher among single people, 50.55 times higher among workers and tradesmen, and 3.36 times higher among people who did not have COVID-19. As religiosity increased, the risk of vaccine refusal decreased 1.037-fold.

基于FEARS数据库研究利培酮不良反应信号

目的基于FEARS数据库为利培酮临床安全使用提供依据。方法收集FAERS数据库中所收集上报的2020年1月1日至2023年3月31日15个季度以利培酮为怀疑药品不良事件报告,经过药品不良反应术语集标准化,利用比例报告比值法(PRR)和报告比值比法(ROR)进行不良反应信号检测。结果提取FAERS数据库中总的原始数据份,利培酮药物的不良反应病例报告11168份,以男性(7525,67.38%)居多;年龄以18~<45岁(2302,20.61%)分布最多;不良事件发生时间-用药日期中以0~30 d为主,1453例,占比为13.01%。ROR法和PRR法共得到不良反应检测中,检测信号526个,其中精神系统检测信号最多(112个)。结论使用利培酮容易导致严重不良反应的发生,尤其是延长患者的住院时间。利培酮所引起的代谢障碍,如肥胖、高泌乳素血症等信号较高,在临床使用过程中,需警惕上述不良反应发生。

Gender Emergency:Fear of the Forsaken

Considered a great example of investigative fiction,Mia per sempre[Mine Forever]which denounces violence against women,encourages them to speak out,seek assistance,and refuse to flee in terror,has been hailed as outstanding work to denounce violence against women.The book is a study of women’s unusual relationships,which are marked by intense love,envious friendships,and unbreakable ties that result in mental instability,irrational behavior,or uncontrollable behavior.Tani’s work has also received recognition for including the knowledgeable perspectives of various specialists who offer a deeper and priceless understanding of these catastrophes occurring individuals’home.This study examines those instances of fear-sharing in relation to women’s independence and ability to move on or start new lives.The main question is how and why Tani’s employs fear.Who are the women or circumstances that cause fear?This paper considers the theoretical discourse on fear developed by scholars of the emotions such as,among others,Jaimal Yogis and Olsson and Phelps in order to examine the circumstances and outcomes of fear fashioned by Tani in her representation of Italian men’s criminal reaction to women’s autonomy.

The Relationship between the intolerance of uncertainty and the fear of COVID-19 in patients awaiting kidney transplantation during the pandemic

Objective:This study aims to identify the relationship between the intolerance of uncertainty and the fear of COVID-19 in patients awaiting kidney transplantation during the COVID-19 pandemic.Methods:This descriptive and cross-sectional study was performed with the participation of 355 individuals.The data were collected with a patient information form,the intolerance of uncertainty scale–short form(IUS),and the fear of COVID-19 scale(FCV-19S).Results:The mean IUS–short form score of the participants was 53.03±5.11,and their mean FCV-19S score was 30.62±4.10.A statistically highly significant positive relationship was identified between the FCV-19S and IUS scores of the participants(r:0.850;P<0.001).Conclusion:As the patients’intolerance of uncertainty increased,their fears of COVID-19 also increased.For patients awaiting kidney transplantation during the COVID-19 pandemic,which is full of challenges,to cope with fear and uncertainty,it is recommended that patients are provided with care with a multidisciplinary team approach.

Fear of missing out: A brief overview of origin, theoretical underpinnings and relationship with mental health

Fear of missing out(FoMO)is a unique term introduced in 2004 to describe a phenomenon observed on social networking sites.FoMO includes two processes;firstly,perception of missing out,followed up with a compulsive behavior to maintain these social connections.We are interested in understanding the complex construct of FoMO and its relations to the need to belong and form stable interpersonal relationships.It is associated with a range of negative life experiences and feelings,due to it being considered a problematic attachment to social media.We have provided a general review of the literature and have summarized the findings in relation to mental health,social functioning,sleep,academic performance and productivity,neuro-developmental disorders,and physical well-being.We have also discussed the treatment options available for FoMo based on cognitive behavior therapy.It imperative that new findings on FoMO are communicated to the clinical community as it has diagnostic implications and could be a confounding variable in those who do not respond to treatment as usual.

Sevoflurane plays a reduced role in cognitive impairment compared with isoflurane: limited effect on fear memory retention

Isoflurane and sevoflurane are both inhalation anesthetics,but in clinical application,sevoflurane has been considered to be less suitable for long-term anesthesia because of its catabolic compounds and potential nephrotoxicity.Nevertheless,recent studies have shown that these two inhalation anesthetics are similar in hepatorenal toxicity,cost,and long-term anesthetic effect.Moreover,sevoflurane possibly has less cognitive impact on young mice.In this study,C57BL/6 mice aged 8–10 weeks were exposed to 1.2%isoflurane or 2.4%sevoflurane for 6 hours.Cognitive function and memory were examined in young mice using the novel object recognition,contextual fear conditioning,and cued-fear extinction tests.Western blot assay was performed to detect expression levels of D1 dopamine receptor,catechol-O-methyltransferase,phospho-glycogen synthase kinase-3β,and total glycogen synthase kinase-3βin the hippocampus.Our results show that impaired performance was not detected in mice exposed to sevoflurane during the novel object recognition test.Contextual memory impairment in the fear conditioning test was shorter in the sevoflurane group than the isoflurane group.Long-term sevoflurane exposure did not affect memory consolidation,while isoflurane led to memory consolidation and reduced retention.Downregulation of hippocampal D1 dopamine receptors and phosphorylated glycogen synthase kinase-3β/total glycogen synthase kinase-3βand upregulation of catechol-O-methyltransferase may be associated with differing memory performance after exposure to isoflurane or sevoflurane.These results confirm that sevoflurane has less effect on cognitive impairment than isoflurane,which may be related to expression of D1 dopamine receptors and catechol-O-methyltransferase and phosphorylation of glycogen synthase kinase-3βin the hippocampus.This study was approved by the Institutional Animal Care and Use Committee,Nanjing University,China on November 20,2017(approval No.20171102).

Effects of Abnormal Early Rearing Environments on Fear Memory in Adult Rats

In the present experiment, Pavlovian fear conditioning was adopted to study the effects of different early rearing environments on fear conditioning in adult rats. Weaned rats were reared in three manipulable environments （enriched, social and isolated conditions）. After 8 weeks, fear conditioning （characterized by percentage of freezing） was observed and analyzed, and rats＇ weight, locomoter activity and foot-shock sensitivity were operated too. The results showed that： （1） Compared with control group, the level of conditioned fear was significantly increased in enriched group, but significantly decreased in isolated group; （2） Enriched and isolated conditions influenced rat＇s weight significantly; （3） Different rearing conditions have no effect on locomoter activity and foot-shock sensitivity. These results indicated that early enriched condition could improve the tone-evoked fear conditioning response, while isolated condition impaired the response.

A comparison of maternal fear of childbirth,labor pain intensity and intrapartum analgesic consumption between primiparas and multiparas:A cross-sectional study

Objectives:To describe and compare fear of childbirth and in-labor pain intensity between primiparas and multiparas and explore the association between the amount of actual pain relief and fear of childbirth.Methods:A convenience sampling method was used.A total of 260 women undergoing spontaneous or induced labor,including 97 primiparas and 163 multiparas,were recruited in a large academic specialized hospital in Guangzhou,China,from February 2018 to August 2019.The clinical data of maternal and neonatal were extracted from a structured electronic medical record system.Other demographic information,such as employment and family monthly income,was collected by a questionnaire.The Numeric Rating Scale(NRS)and the Chinese version of the Childbirth Attitude Questionnaire(C-CAQ)were applied to assess maternal in-labor pain intensity and fear of childbirth.The analgesic consumption and the frequency of manual boluses as rescue analgesia were stored and collected from the analgesia pump.Results:Eighty-two(84.5%)primiparas and ninety-nine(60.7%)multiparas received epidural analgesia(P<0.001).In the epidural subgroup,the primiparous average fear of childbirth(36.46±10.93)was higher than that of the multiparas(32.06±10.23)(P¼0.007).However,multiparas reported more intense in-labor pain[8.0(8.0,9.0)vs.8.0(7.0,8.0)],had more successful manual boluses per hour[2.68(1.65,3.85)vs.1.77(0.90,2.47)],more hourly analgesic consumption[23.00(16.00,28.25)vs.17.24(11.52,21.36)mL]and more average analgesic consumption[0.35(0.24,0.45)vs.0.26(0.19,0.35)mL/(h$kg)]than the primiparas(P<0.05).Spearman’s correlation analysis showed that the maximum in-labor pain was weakly positively correlated with fear of childbirth(r¼0.09)(P<0.05),hourly analgesic consumption(r¼0.16)(P<0.01)and average analgesic consumption(r¼0.17)(P<0.05).No statistically significant association was uncovered between analgesic consumption and maternal fear of childbirth.Conclusions:Fear of childbirth is a potential predictor of labor pain intensity.Further study is needed to explore its role and value in pain management during delivery.Parity is not a determinant of pain relief use and should not be a preconceived preference of obstetric care team members to determine the distribution of epidural analgesia,especially when analgesia resources are insufficient.

Fear can be more harmful than the severe acute respiratory syndrome coronavirus 2 in controlling the corona virus disease 2019 epidemic

The current corona virus disease 2019 outbreak caused by severe acute respiratory syndrome coronavirus 2 started in Wuhan,China in December 2019 and has put the world on alert.To safeguard Chinese citizens and to strengthen global health security,China has made great efforts to control the epidemic.Many in the global community have joined China to limit the epidemic.However,discrimination and prejudice driven by fear or misinformation have been flowing globally,superseding evidence and jeopardizing the anti-severe acute respiratory syndrome coronavirus 2 efforts.We analyze this phenomenon and its underlying causes and suggest practical solutions.