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Controlling disease spread on networks with feedback mechanism
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作者 王俐 颜家壬 +1 位作者 张建国 刘自然 《Chinese Physics B》 SCIE EI CAS CSCD 2007年第9期2498-2502,共5页
Many real-world networks have the ability to adapt themselves in response to the state of their nodes. This paper studies controlling disease spread on network with feedback mechanism, where the susceptible nodes are ... Many real-world networks have the ability to adapt themselves in response to the state of their nodes. This paper studies controlling disease spread on network with feedback mechanism, where the susceptible nodes are able to avoid contact with the infected ones by cutting their connections with probability when the density of infected nodes reaches a certain value in the network. Such feedback mechanism considers the networks' own adaptivity and the cost of immunization. The dynamical equations about immunization with feedback mechanism ave solved and theoretical predictions are in agreement with the results of large scale simulations. It shows that when the lethality a increases, the prevalence decreases more greatly with the same immunization g. That is, with the same cost, a better controlling result can be obtained. This approach offers an effective and practical policy to control disease spread, and also may be relevant to other similar networks. 展开更多
关键词 complex network systems disease spread feedback mechanism
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Enhancing customers prevention efforts:An incentive feedback mechanism design
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作者 Sun Huan Wang Haiyan 《Journal of Southeast University(English Edition)》 EI CAS 2021年第4期436-444,共9页
To improve the inefficient prevention caused by customers unwillingness to adopt prevention strategies in health management,an incentive feedback mechanism that is based on game theory and contract design theory is in... To improve the inefficient prevention caused by customers unwillingness to adopt prevention strategies in health management,an incentive feedback mechanism that is based on game theory and contract design theory is introduced.The conditions for making customers and health maintenance organizations(HMOs)willing to participate in the proposed mechanism are given.A dual nonlinear programming model is used to identify the optimal prevention effort of customers and the pricing strategy of HMOs.Results show that to generate increased benefits,HMOs need to consider cost sharing when customers are not familiar with the proposed health services.When health services are gradually accepted,the cost sharing factor can be gradually reduced.Simulation shows that under random circumstances in which the market reaches a certain size,the proposed method exhibits a positive network externality.Motivated by network externality,HMOs only need to make their customers understand that the larger the number of participants,the greater the utility of each person.Such customers may then spontaneously invite others to purchase insurance. 展开更多
关键词 customers prevention efforts incentive feedback mechanism healthcare service health pricing strategy health service optimization
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Feedback Mechanism-driven Mutation Reptile Search Algorithm for Optimizing Interpolation Developable Surfaces
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作者 Gang Hu Jiao Wang +1 位作者 Xiaoni Zhu Muhammad Abbas 《Journal of Bionic Engineering》 SCIE EI CSCD 2024年第1期527-571,共45页
Curvature lines are special and important curves on surfaces.It is of great significance to construct developable surface interpolated on curvature lines in engineering applications.In this paper,the shape optimizatio... Curvature lines are special and important curves on surfaces.It is of great significance to construct developable surface interpolated on curvature lines in engineering applications.In this paper,the shape optimization of generalized cubic ball developable surface interpolated on the curvature line is studied by using the improved reptile search algorithm.Firstly,based on the curvature line of generalized cubic ball curve with shape adjustable,this paper gives the construction method of SGC-Ball developable surface interpolated on the curve.Secondly,the feedback mechanism,adaptive parameters and mutation strategy are introduced into the reptile search algorithm,and the Feedback mechanism-driven improved reptile search algorithm effectively improves the solving precision.On IEEE congress on evolutionary computation 2014,2017,2019 and four engineering design problems,the feedback mechanism-driven improved reptile search algorithm is compared with other representative methods,and the result indicates that the solution performance of the feedback mechanism-driven improved reptile search algorithm is competitive.At last,taking the minimum energy as the evaluation index,the shape optimization model of SGC-Ball interpolation developable surface is established.The developable surface with the minimum energy is achieved with the help of the feedback mechanism-driven improved reptile search algorithm,and the comparison experiment verifies the superiority of the feedback mechanism-driven improved reptile search algorithm for the shape optimization problem. 展开更多
关键词 Reptile search algorithm feedback mechanism Adaptive parameter Mutation strategy SGC-Ball interpolation developable surface Shape optimization
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BFM:A Bus-Like Data Feedback Mechanism Between Graphics Processor and Host CPU
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作者 DENG Junyong JIANG Lin 《Journal of Shanghai Jiaotong university(Science)》 EI 2020年第5期615-622,共8页
Graphics processors have received an increasing attention with the growing demand for gaming,video streaming,and many other applications.During the graphics rendering with OpenGL,host CPU needs the runtime attributes ... Graphics processors have received an increasing attention with the growing demand for gaming,video streaming,and many other applications.During the graphics rendering with OpenGL,host CPU needs the runtime attributes to move on to the next procedure of rendering,which covers almost all the function units of graphics pipeline.Current methods suffer from the memory capacity issues to hold the variables or huge amount of data parsing paths which can cause congestion on the interface between graphics processor and host CPU.This paper refers to the operation principle of commuting bus,and proposes a bus-like data feedback mechanism(BFM)to traverse all the pipeline stages and collect the run-time status data or execution error of graphics rendering,then send them back to the host CPU.BFM can work in parallel with the graphics rendering logic.This method can complete the data feedback ta.sk easily with only 0.6%increase of resource utilization and has no negative impact on performance,which also obtains 1.3 times speed enhancement compared with a traditional approach. 展开更多
关键词 data feedback mechanism run-time attributes OjienGL graphics processor host CPU
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CISK,EVAPORATION-WIND FEEDBACK MECHANISM AND 30—60 DAY OSCILLATIONS IN THE TROPICAL ATMOSPHERE
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作者 赵强 付遵涛 +1 位作者 陈炯 刘式适 《Acta meteorologica Sinica》 SCIE 1997年第2期164-175,共12页
A baroclinic semi-geostrophic model with evaporation-wind feedback mechanism(EWFM) and CISK is established,two non-dimensional parameters a and η are introduced to represent EWFM and CISK,respectively.Analytic soluti... A baroclinic semi-geostrophic model with evaporation-wind feedback mechanism(EWFM) and CISK is established,two non-dimensional parameters a and η are introduced to represent EWFM and CISK,respectively.Analytic solutions of the model system are obtained,dynamics analyses and the model atmosphere calculations further confirm that EWFM and CISK are very important physical processes in leading to the low-frequency oscillations in the tropics. 展开更多
关键词 CISK(conditional instability of the second kind) EWFM (evaporation-wind feedback mechanism) LFO(low-frequency oscillation) EWFM-CISK-Rossby wave EWFM-CISK-Kelvin wave
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Analysis of epidemic spreading with feedback mechanism in weighted networks
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作者 Jiancheng Zhang Jitao Sun 《International Journal of Biomathematics》 2015年第1期81-91,共11页
In this paper, we investigate a new model with a generalized feedback mechanism in weighted networks. Compare to previous models, we consider the initiative response of people and the important impact of nodes with di... In this paper, we investigate a new model with a generalized feedback mechanism in weighted networks. Compare to previous models, we consider the initiative response of people and the important impact of nodes with different edges on transmission rate as epidemics prevail. Furthermore, by constructing Lyapunov function, we prove that the disease-free equilibrium E^0 is globally asymptotically stable as the epidemic threshold R^*〈 1. When R^* 〉 1, we obtain the permanence of epidemic and the local stability of endemic equilibrium E*. Finally, one can find a good agreement between numerical simulations and our analytical results. 展开更多
关键词 SIS model weighted network feedback mechanism global analysis
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Virtual Plant Modeling Based on Mutual Feedback of Function-structure 被引量:1
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作者 范振岐 司春景 +2 位作者 曹洪武 韩旭 李文华 《Agricultural Science & Technology》 CAS 2011年第12期1972-1974,共3页
[Objective] To study virtual plant modeling based on mutual feedback of function-structure.[Method] With the analysis of the shortcomings of current virtual plant modeling method,the modeling with the idea of function... [Objective] To study virtual plant modeling based on mutual feedback of function-structure.[Method] With the analysis of the shortcomings of current virtual plant modeling method,the modeling with the idea of function-structure mutual feedback was put forward,and the steps of this modeling were elaborated,including the determination of morphological structure model,biomass production model,biomass allocation model,organ reconstruction model,and the integration method of function model and morphological structure model.[Results] The breakthrough of function-structure mutual feedback based mechanism from the boundaries of physiological ecology model and morphological structure model can solve the difficulty of data transmission between the two models and build an integrated model from the two,which can effectively reflect the incidence relation between plant morphology and function,and more suitable for the growth mechanisms of plants.This modeling approach has significant advantages in the dynamic simulation of plant growth.[Conclusion] The virtual plant modeling based on function-structure mutual feedback provides basis for the simulation of plant growth status in the next stage,and has important significance for the accurate simulation of the dynamic growth process of plant. 展开更多
关键词 Structure-function model Mutual feedback mechanism Virtual plant
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A Large-Scale Group Decision Making Model Based on Trust Relationship and Social Network Updating
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作者 Rongrong Ren Luyang Su +2 位作者 Xinyu Meng Jianfang Wang Meng Zhao 《Computer Modeling in Engineering & Sciences》 SCIE EI 2024年第1期429-458,共30页
With the development of big data and social computing,large-scale group decisionmaking(LGDM)is nowmerging with social networks.Using social network analysis(SNA),this study proposes an LGDM consensus model that consid... With the development of big data and social computing,large-scale group decisionmaking(LGDM)is nowmerging with social networks.Using social network analysis(SNA),this study proposes an LGDM consensus model that considers the trust relationship among decisionmakers(DMs).In the process of consensusmeasurement:the social network is constructed according to the social relationship among DMs,and the Louvain method is introduced to classify social networks to form subgroups.In this study,the weights of each decision maker and each subgroup are computed by comprehensive network weights and trust weights.In the process of consensus improvement:A feedback mechanism with four identification and two direction rules is designed to guide the consensus of the improvement process.Based on the trust relationship among DMs,the preferences are modified,and the corresponding social network is updated to accelerate the consensus.Compared with the previous research,the proposedmodel not only allows the subgroups to be reconstructed and updated during the adjustment process,but also improves the accuracy of the adjustment by the feedbackmechanism.Finally,an example analysis is conducted to verify the effectiveness and flexibility of the proposed method.Moreover,compared with previous studies,the superiority of the proposed method in solving the LGDM problem is highlighted. 展开更多
关键词 Large-scale group decision making social network updating trust relationship group consensus feedback mechanism
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Need for education of psychiatric evaluation of offenders with mental disorders:A questionnaire survey for Japanese designated psychiatrists
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作者 Akihiro Shiina Tomihisa Niitsu +1 位作者 Masaomi Iyo Chiyo Fujii 《World Journal of Psychiatry》 SCIE 2024年第5期726-734,共9页
BACKGROUND The management of offenders with mental disorders has been a significant concern in forensic psychiatry.In Japan,the introduction of the Medical Treatment and Supervision Act in 2005 addressed the issue.How... BACKGROUND The management of offenders with mental disorders has been a significant concern in forensic psychiatry.In Japan,the introduction of the Medical Treatment and Supervision Act in 2005 addressed the issue.However,numerous psychiatric patients at risk of violence still find themselves subject to the administrative involuntary hospitalization(AIH)scheme,which lacks clarity and updated standards.AIM To explore current as well as optimized learning strategies for risk assessment in AIH decision making.METHODS We conducted a questionnaire survey among designated psychiatrists to explore their experiences and expectations regarding training methods for psychiatric assessments of offenders with mental disorders.RESULTS The findings of this study’s survey suggest a prevalent reliance on traditional learning approaches such as oral education and on-the-job training.CONCLUSION This underscores the pressing need for structured training protocols in AIH consultations.Moreover,feedback derived from inpatient treatment experiences is identified as a crucial element for enhancing risk assessment skills. 展开更多
关键词 Forensic psychiatry Administrative involuntary hospitalization Psychiatric assessment Risk assessment Mental disorders Training protocols Clinical practice Structured learning feedback mechanisms Program development
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Fundamental Principles behind Climate Change
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作者 Haiyan DAI 《Meteorological and Environmental Research》 2024年第4期21-23,共3页
The attribution of climate change is complex,and the current mainstream view is more inclined towards human activities and carbon dioxide emissions from fossil fuels.Any complex problem is composed of basic principles... The attribution of climate change is complex,and the current mainstream view is more inclined towards human activities and carbon dioxide emissions from fossil fuels.Any complex problem is composed of basic principles.This article elaborates on the basic logic behind climate change(a global hot topic)through basic principles such as reaction types,carbon thermal properties of biomass energy,greenhouse gas attribution,ecological basic theory,and energy cycle. 展开更多
关键词 Climate change feedback mechanisms Fundamental principles DISASTERS
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Feed back Mechanism in Decision Support Systems
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作者 Sun Zhanshan(Institute of SE. Dalian Maritime University, 116024, P. R. China) 《Journal of Systems Engineering and Electronics》 SCIE EI CSCD 1997年第2期53-59,共7页
Feedback mechanism is a specific feature of control systems, however, the similarity has been found in decision support systems. Just because of this, the DSS can provide a flexible learning and thinking environment, ... Feedback mechanism is a specific feature of control systems, however, the similarity has been found in decision support systems. Just because of this, the DSS can provide a flexible learning and thinking environment, and help decision maker to solve semistructured and unstructured problems actively and creatively. In this paper, the role and type of the feedback in decision making are discussed from different point of view. This is also true in DSS because it supports decision making. The feedback design, especially the feedback interface design, is described through a case of practice DSS. Based on these points, the feedback mechanism is an important feature of DSS, and it is one of the differences between DSS and MIS. 展开更多
关键词 feedback mechanism Decision making Decision support system feedback interface design.
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Attribution of Persistent Precipitation in the Yangtze–Huaihe River Basin during February 2019 被引量:2
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作者 Zhixuan WANG Jilin SUN +2 位作者 Jiancheng WU Fangyue NING Weiqi CHEN 《Advances in Atmospheric Sciences》 SCIE CAS CSCD 2020年第12期1389-1404,共16页
In February 2019,a month-long persistent precipitation event occurred in the Yangtze–Huaihe River basin.The geopotential height field that affected the duration of this frontal rainfall was divided into a high-latitu... In February 2019,a month-long persistent precipitation event occurred in the Yangtze–Huaihe River basin.The geopotential height field that affected the duration of this frontal rainfall was divided into a high-latitude part and a lowlatitude part for analysis.In the high-latitude part,a two-wave structure led to quasi-stationary circulation,and the change of both the blocking high pressure and Arctic Oscillation phase caused cold air to invade South China continuously and changed the frontal position.In mid-to-low latitudes,the persistent precipitation showed quasi-biweekly oscillation characteristics.The so-called“subtropical high–precipitation–anticyclone”(SHPA)feedback mechanism blocked the circulation systems in the mid-to-low latitudes and provided a continuous supply of water vapor for precipitation.As for the effect of sea surface temperature,the western North Pacific anomalous anticyclone stimulated by El Niño strengthened the intensity of the southerly wind and provided support for the redevelopment of the anticyclone system in the SHPA feedback mechanism.The sea surface temperature anomaly in the South China Sea provided sensible heating for precipitation,and convergent rising airflow was conducive to the occurrence of precipitation.Additionally,the SHPA mechanism provides a reliable basis for the prediction of persistent precipitation in winter in the mid-to-low latitudes. 展开更多
关键词 persistent precipitation feedback mechanism latent heat
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Factors contributing to rapid decline of Arctic sea ice in autumn 被引量:2
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作者 LI Shuyao CUI Hongyan +6 位作者 XU Junli GONG Xiang QIAO Fangli YANG Yanzhao WANG Ping HAN Yuqun SHAN Feng 《Advances in Polar Science》 CSCD 2021年第2期96-104,共9页
Autumn Arctic sea ice has been declining since the beginning of the era of satellite sea ice observations.In this study,we examined the factors contributing to the decline of autumn sea ice concentration.From the Beau... Autumn Arctic sea ice has been declining since the beginning of the era of satellite sea ice observations.In this study,we examined the factors contributing to the decline of autumn sea ice concentration.From the Beaufort Sea to the Barents Sea,autumn sea ice concentration has decreased considerably between 1982 and 2020,and the rates of decline were the highest around the Beaufort Sea.We calculated the correlation coefficients between sea ice extent(SIE)anomalies and anomalies of sea surface temperature(SST),surface air temperature(SAT)and specific humidity(SH).Among these coefficients,the largest absolute value was found in the coefficient between SIE and SAT anomalies for August to October,which has a value of−0.9446.The second largest absolute value was found in the coefficient between SIE and SH anomalies for September to November,which has a value of−0.9436.Among the correlation coefficients between SIE and SST anomalies,the largest absolute value was found in the coefficient for August to October,which has a value of−0.9410.We conducted empirical orthogonal function(EOF)analyses of sea ice,SST,SAT,SH,sea level pressure(SLP)and the wind field for the months where the absolute values of the correlation coefficient were the largest.The first EOFs of SST,SAT and SH account for 39.07%,63.54%and 47.60%of the total variances,respectively,and are mainly concentrated in the area between the Beaufort Sea and the East Siberian Sea.The corresponding principal component time series also indicate positive trends.The first EOF of SLP explains 41.57%of the total variance.It is mostly negative in the central Arctic.Over the Beaufort,Chukchi and East Siberian seas,the zonal wind weakened while the meridional wind strengthened.Results from the correlation and EOF analyses further verified the effects of the ice-temperature,ice-SH and ice-SLP feedback mechanisms in the Arctic.These mechanisms accelerate melting and decrease the rate of formation of sea ice.In addition,stronger meridional winds favor the flow of warm air from lower latitudes towards the polar region,further promoting Arctic sea ice decline. 展开更多
关键词 Arctic sea ice rapid decline empirical orthogonal function feedback mechanisms
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Contention avoidance using dual-fuzzy assembly threshold algorithm in optical burst switching networks
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作者 杨九如 王钢 贾世楼 《Journal of Harbin Institute of Technology(New Series)》 EI CAS 2009年第4期465-468,共4页
To avoid burst contention efficiently,on the basis of feedback-based source flow-rate control(SFC) strategy,a novel fuzzy-control-based assembly algorithm,called dual-fuzzy assembly threshold(DFAT),is proposed in an o... To avoid burst contention efficiently,on the basis of feedback-based source flow-rate control(SFC) strategy,a novel fuzzy-control-based assembly algorithm,called dual-fuzzy assembly threshold(DFAT),is proposed in an optical burst switching network.In our algorithm,according to the variations of burst assembly period and the interarrival of burst control packet,the traffic states of edge-switching nodes and core-switching nodes are first obtained.Then,the assembly threshold of bursts is set dynamically in order to operate the source traffic management from the information of traffic states.The performance of DFAT algorithm on burst loss probability is evaluated,and simulation results show that,compared with conventional assembly algorithms,the proposed scheme can constrain the birth of burst contention efficiently,when being a heavy load state of network. 展开更多
关键词 optical burst switching contention avoidance burst assembly dual feedback mechanism
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A Bioelectromagnetic Proposal Approaching the Complex Challenges of COVID-19
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作者 Andras Szasz 《Open Journal of Biophysics》 2021年第1期1-67,共67页
The COVID-19 pandemic has experienced unprecedented limitations and extraordinary scientific efforts to address this exceptional situation. Despite blanket closures that have resulted in significant financial constrai... The COVID-19 pandemic has experienced unprecedented limitations and extraordinary scientific efforts to address this exceptional situation. Despite blanket closures that have resulted in significant financial constraints and losses around the world, research has an “unlimited” budget, with an exceptional concentration of medical and scientific care on a single topic: understanding the mechanisms for overcoming the disease. A large number of clinical trials have been launched with different drugs that have been behind different concepts and solutions. I would like to focus on the complexity aspect of COVID-19. Living systems are organized in a complex way, which implies dynamic stochastic phenomena, and deterministic reductionism can mislead research. When research focuses on individual molecules or pathways as products, it is distracted from the processes in which these products operate, thus neglecting the complex interactions between regulations and feedback controls. Common problems in product-oriented research are articulated as “double-edged swords”, “Janus behavior”, “two-sided action”, with a simple question: “friend or foe?” I focus on the missing complexity. I propose a bioelectromagnetic process that can maintain a complex approach, affecting processes rather than products. This hypothetical proposal is not a comprehensive solution. Complexity itself limits the overall effects of causing “miracles”. Well-designed electromagnetic effects can support current efforts and, in combination with intensively developed pharmaceuticals, bring us closer to a pharmaceutical solution against COVID-19. 展开更多
关键词 SARS-Cov-2 HOMEOSTASIS feedback mechanisms Biophysical Selection Modulated-Electro-Hyperthermia mEHT Oncothermia VACCINATION
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Cardiac Neurons Firing Preceding Cortical Neurons Firing by Variable Time Equivalent to RP before Conscious Act
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作者 Amna A1Faki 《Journal of Philosophy Study》 2011年第4期305-309,共5页
The signals and the neuronal mechanisms that underlying the behavior, actions, and action-directed goals in man and animals during conscious state are not fully understood, and the neuro-dynamic mechanisms and the sou... The signals and the neuronal mechanisms that underlying the behavior, actions, and action-directed goals in man and animals during conscious state are not fully understood, and the neuro-dynamic mechanisms and the source of these neuronal signals are not authenticated. Temporal judgment alone can neither account for neural signaling necessary for emergence of conscious act nor explain RP (Readiness Potential, the accepted neural correlate time needed for the neurons to fire) that precedes the onset of action or the latency time of 0.5 ms that precedes the conscious act found by Libet. Neuronal feedback mechanisms between the heart and the brain seem feasible and logical suggestions to be considered, so clearly, I would suggest that the onset of a conscious-directed goal, conscious action, freewill, intension, and the neural signals and mechanisms that control them may depend upon the interaction between two sources: (1) the brain and (2) the heart. The temporal-cardiac (neural system) interaction has been well established in heart-brain interaction studies by many workers who found that the work of the heart precedes that of the brain in EEG (electroencephalography) findings in conscious stimulation, which may explain and account for RP time and the 0.5 ms latency period of Libet's important findings. According to my hypothesis (AlFaki 2009) and views, the temporal neurons in the soma to-sensory cortex will respond to conscious stimulation only after receiving neuronal signals from the cardiac neurons in the neural plexus of the heart; after variable millisecond equivalent to RP or Libet's latency period prior to temporal neuronal firinging in response to conscious act, this time is the time needed by cardiac neurons to process and signal information to the brain through feedback mechanism and heart-brain interaction. 展开更多
关键词 feedback mechanisms latency period RP (Readiness Potential) freewill INTENSION consciousness cognition neural plexus heart-brain interaction
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Construction of an intelligent patient satisfaction assessment system and its application in emergency management
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作者 Yi-Bo Wu Jin-Yi Meng +3 位作者 Hong-Xue Chen Dong-Yun Li Shu-Xian Xu Tao Wang 《TMR Clinical Research》 2020年第1期30-30,31-35,共6页
Hospital emergency management work is of great importance which not only related to the life and health of the people but also related to social stability.It is necessary to construct and improve the patient satisfact... Hospital emergency management work is of great importance which not only related to the life and health of the people but also related to social stability.It is necessary to construct and improve the patient satisfaction assessment system so that doctors and patients can interact in a timely and effective manner,and the hospital can alert or respond promptly.This study constructs a closed-loop emergency management system consisting of patient-end,data center and decision-making-end,and apply the feedback information to hospital emergency management.In the preliminary applications,the system has a significant effect on the hospital emergency management mechanism.The researchers will improve the system in the follow-up study。 展开更多
关键词 Hospital Emergency Management Patient Satisfaction feedback mechanism
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Optimized design of high power plasma inverter based on bionics 被引量:3
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作者 王振民 张芩 吴祥淼 《China Welding》 EI CAS 2011年第3期37-41,共5页
Through the inspiration of the reliability mechanism of human body, it is obvious that the bionic methods can be used as a reference for the optimized design of high power plasma inverter. On this basis, the high powe... Through the inspiration of the reliability mechanism of human body, it is obvious that the bionic methods can be used as a reference for the optimized design of high power plasma inverter. On this basis, the high power plasma inverter can be composed of several high power density intelligent power electric building blocks ( IPEBB ) , which are controlled by intelligent controller with the capability of self-management and can be regarded as the cell of the inverter. All of these IPEBB can be controllable and cooperative through distributed communication structure with digital control. This structure can be regarded as the nerve of the inverter. In each IPEBB, the advance mechanical feedback mechanism is adopted to suppress the magnetic bins, over-current protection and gate driving for the high power switches. A 75 kW Prototype constructed by IPEBBs was built to test the performance. Experimental results verify the feasibility of the proposed approach, and the bionic design methods can benefit the optimized design of high power plasma inverter. 展开更多
关键词 PLASMA plasma inverter BIONICS advance mechanical feedback power electronic building block
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A Study on the Molecular Switch of Gene Expression of the Mouse Heart Nuclear DNA Fragments
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作者 袁明秀 JIN +6 位作者 Rui Niu Weiran Chen Zhijun Zhang Zhihong 《High Technology Letters》 EI CAS 2001年第4期1-7,共7页
It is observed by in situ stain that LDH (1 5) ...nNAD + can probably enter the nucleopore and can be bound bound specifically with the genes that encode them. During the in vitro expression, the dilution of heart nuc... It is observed by in situ stain that LDH (1 5) ...nNAD + can probably enter the nucleopore and can be bound bound specifically with the genes that encode them. During the in vitro expression, the dilution of heart nuclear DNA fragments could enhance the expression activity of LDH/DNA and the amount of expressed LDH (1 5) is in proportion to the amount of dissociable LDH (1 5) on the LDH/DNA. With the integration of 14C Leu to the proteins, it is also observed that the addition of LDH (1 5) ...nNAD + can suppress the in vitro expression activity of LDH/DNA. AFM observation shows that the regulation sequence at the both ends of active genes may be bound with such active factors as proteins encoded by the genes which probably is the main molecular switch of gene expression and regulation we have been always searching for. Our work shows the prospective application of the combination of AFM and isotope labeling in the research of biological reaction. 展开更多
关键词 Molecular switch of gene expression Positive and negative feedback regulation mechanism Gene expression and regulation AFM
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MSLFuzzer:black-box fuzzing of SOHO router devices via message segment list inference
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作者 Yixuan Cheng Wenqing Fan +3 位作者 Wei Huang Jingyu Yang Gaoqing Yu Wen Liu 《Cybersecurity》 EI CSCD 2024年第4期89-109,共21页
The popularity of small office and home office routers has brought convenience,but it also caused many security issues due to vulnerabilities.Black-box fuzzing through network protocols to discover vulnerabilities bec... The popularity of small office and home office routers has brought convenience,but it also caused many security issues due to vulnerabilities.Black-box fuzzing through network protocols to discover vulnerabilities becomes a viable option.The main drawbacks of state-of-the-art black-box fuzzers can be summarized as follows.First,the feedback process neglects to discover the mising felds in the raw message.Secondly,the guidance of the raw message content in the mutation process is aimless.Finally,the randomized validity of the test case structure can cause most fuzzing tests to end up with an invalid response of the tested device.To address these challenges,we propose a novel black-box fuzzing framework called MSL Fuzzer.MSL Fuzzer infers the raw message structure according to the response from a tested device and generates a message segment list.Furthermore,MSL Fuzzer performs semantic,sequence,and stability analyses on each message segment to enhance the complementation of missing fields in the raw message and guide the mutation process.We construct a dataset of 35 real-world vulnerabilities and evaluate MSL Fuzzer.The evaluation results show that MSL Fuzzer can find more vulnerabilities and elicit more types of responses from fuzzing targets.Additionally,MSL Fuzzer successfully discovered 10 previously unknown vulnerabilities. 展开更多
关键词 Vulnerability discovery Black-box fuzzing SOHO routers feedback mechanism
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