啮齿类动物Playfighting的行为学研究进展

Playfighting是一种常见的社会性互动形式,具有互惠性和合作性等特点。其贯穿于动物的整个生命周期,并且会通过影响动物的社交、认知和运动等进一步影响大脑的执行功能。啮齿类动物的playfighting行为因具有易识别、易量化等特点,而被广泛研究。本文主要以大鼠和金仓鼠为例,整理概述了近年来啮齿类动物playfighting行为的研究现状,包括行为模式及其相关影响因素,希望为今后进一步研究playfighting行为提供参考。

China Focus:China′s MA60 Firefighting Aircraft Moves One Step Closer To Obtaining Certification

BEIJING,Dec.20 (Xinhua)——China′s independently-developed MA60 firefighting aircraft,a new member of the Modern Ark multipurpose aircraft family,is progressing forward on its airworthiness certification process,according to the Aviation Industry Corporation of China (AVIC).As an aircraft model tailored to serve emergency rescue missions,MA60 successfully completed a key test flight,which consisted of hedgehopping and dropping six tonnes of water,said the AVIC,China′s leading aircraft manufacturer.The aircraft successfully conducted the water drop over the scheduled site at a very low altitude of 55 meters.The test took place at an airport in southwest China′s Sichuan Province.

Fight fire with fire?Promoting physical activity and health through active video games

Physical inactivity has been identified as one of the leading causes of many chronic diseases such as cardiovascular disease,type 2 diabetes,and obesity.Technology such as video games plays a complicated role in physical inactivity—much like a double-edged sword.Traditionally,video games have contributed to the epidemic of physical inactivity and have

Whole-genome resequencing infers genomic basis of giant phenotype in Siamese fighting fish(Betta splendens)

Understanding the genetic basis of phenotypes is of importance in evolutionary biology and for genetic improvement of economically valuable animals.The giant phenotype of the fighting fish,Betta splendens,provides a unique opportunity to explore the genetic architecture of overgrowth in body size.As such,we re-sequenced and analyzed the genomes of 54 fighting fish.Genome-wide FST and selective sweep analyses using 3582429 DNA variants revealed three genomic regions at chr1,chr9,and chr11 that were associated with the giant phenotype.With a total length of~3.5 Mb,these regions showed high divergence between the giant and non-giant bettas.In contrast,no signature of selection was detected in the wild-type fish.Transcriptome analysis of brain and muscle samples from giant and normal bettas identified 14 candidate genes that were likely responsible for the giant phenotype.Overall,our data provide novel insights into the genetic basis of body size variation.The genome sequences,transcriptome sequences,DNA sequence variants,and candidate genes for body size provide valuable resources for further biological and evolutionary studies,as well as for rapid improvement in growth-related traits.

Three-Dimensional Kinematics Simulation of Robot Fighting Platform in Virtual Environment

A method of 3 D kinematics simulation of robot fighting platform （RFP） in virtual environment is proposed with the aim of enhancing vision telepresence. Based on the theory of space coordinate transformation, kinematics equat!ons of RFP are formulated; followed by applying a method of modeling using 3DMAX software to build an RFP＇s 3D geometric model before a 3D kinematics simulation system of RFP is completed based on virtual reality technology and Open Inventor VC ＋ ＋. Test results have indicated that this system can perform RFP＇s kinematics simulation in virtual environment. It can also imitate RFP＇s motion states and environmental features well. Moreover, not only can better real-time performances and interactions be achieved but also operator＇s vision telepresence be enhanced, therefore this approach may help lay the foundation for the realization of RFP＇s teleoperation with vision telepresence.

New neuroprotective perspectives in fighting oxidative stress and improving cellular energy metabolism by oleocanthal

Neurodegenerative diseases are a heterogeneous group of disorders characterized by a progressive dysfunction and death of neural cells which lead to compromised motor or cognitive function.Morphologically,the loss of neuron is associated with both gliosis and,frequently,with abnormal accumulation of extracellular and intracellular filamentous deposit in specific cell types.With a rapidly increasing aging population,these diseases are becoming a primary health problem(Albers and Beal,2000).

Work together to fight the epidemic

As is known to all,Chinese people once again face the virus crisis-COVID-19.In the beginning,people all over China were in panic.But the epidemic is getting better with the efforts of all Chinese people.Many ordinary people are playing a role in stopping the epidemic.My parents are among them.My father,a common government official.

Using Link Analysis Technique with a Modified Shortest-Path Algorithm to Fight Money Laundering

Effective link analysis techniques are needed to help law enforcement and intelligence agencies fight money laundering. This paper presents a link analysis technique that uses a modified shortest-path algorithms to identify the strongest association paths between entities in a money laundering network. Based on two-tree Dijkstra and Priority＇First-Search （PFS） algorithm, a modified algorithm is presented. To apply the algorithm, a network representation transformation is made first.

Promoting the fighting spirit against the pandemic and planning a new chapter of nursing

2020 has been an extraordinary year.After the outbreak of the coronavirus disease 2019(COVID-19),vast numbers of nurses have made an exceptional contribution to improving the recovery and reducing the mortality of patients.On International Nurses Day,President Xi Jinping extended festive congratulations and sincere condolences to nurses nationwide,and fully affirmed their important contributions in winning the battle against the pandemic in China and ensuring the safety and health of people in all countries.This is a great encouragement to us.We will bear in mind the President’s instructions,implement the fighting spirit against the pandemic in our work,insist on the people’s supremacy,importance of putting life first,and ensure the health of the people.

Adapt to New Normal State of Environmental Protection,Fight a Tough Fight,and Make Full Efforts to Build a Beautiful Xi'an

In China, economic growing speed converts from high speed to moderate and high speed; economic structure enters from moderate and low end to moderate and high end; development power converts from investment drive to innovation drive, and investment of resource and environ- ment factors presents declining trend. Spatial pattern of economy development is changing greatly, which needs eco-civilization construction and en- vironmental protection field continuously adjusting focus, environmental rules and laws correspondingly regulating, eco-civilization construction and environmental protection field also entering into new normal state. It requires scientifically understanding, actively adapting to and responding to new normal state of eco-civilization construction and environmental protection,and fighting a tough fight. Firstly, we should handle with the relationship between environment and economy, and strive to explore the way of environmental protection. Secondly, we should insist protection priority and prevention oriented,and promote transformation of environmental management strategy. Finally, we should accelerate to promote eco-civilization system reform and environmental protection management system reform, and further promote environmental protection work in Xi＇an on new level from eight aspects.

China Will Fight to the End If US Keeps Escalating Trade Frictions: MOC

“China will fight to the end if the United States continues to escalate trade frictions,”the Ministry of Commerce(MOC)said recently.China will not give ground on issues of principle during bilateral economic and trade talks,which are clearly stated in a white paper on bilateral trade consultations issued earlier this month,MOC spokesperson Gao Feng said.In response to the new threat of tarrifs by the United States,Gao said China is firmly against US unilateralism and bullying.

Reduction of serotonergic gene expression in the raphe nuclei of the midbrain under positive fighting experience in male mice

The concept of a major inhibitory role of serotonin in aggressive behavior is widely accepted by investigators. There was ample evidence that a pharmacologically-induced increase in the serotonin activity attenuates agonistic behavior in animals, and that the manipulations inhibiting the brain serotonergic system can elicit aggressiveness in male mice and rats. Repeated experience of aggression in daily agonistic interactions has been shown to reduce serotonin activity in brain of victorious male mice. The study aimed to analyze expression of the serotonergic genes -Tph2, Sert, Maoa and Htr1a, as well as the Bdnf and Creb genes in the midbrain raphe nuclei of male mice with positive fighting experience in daily encounters and male mice with the same track record of aggression followed by two-week no-fight period. It has been shown that mRNA levels of the serotonergic and Creb genes are reduced in the winners in comparison with male mice without consecutive positive fighting experience of aggression. After the fighting deprivation the Tph2, Sert, Bdnf and Creb genes recover their expression while mRNA levels of the Maoa and Htr1a genes proceed at a significantly higher level as compared with the respective controls. Downregulation of serotonergic genes is indicative of the inhibition of serotonergic activity under repeated experience of aggression. Nevertheless recovering of Tph2 and Sert gene expression and overexpression of the Maoa and Htr1a genes after no-fight period suggest that changes in brain serotonergic activity are not main cause of the behavioral pathology developing in male mice in this experimental context.

Comparison of the Anthelmintic Efficacy of Three Commercial Products against Ascarids and Capillaria SPP. in Fighting Cocks

The aim of the present study was to evaluate the anthelmintic efficacy of three commercial compounds against ascarids and Capillaria spp. in naturally infected fighting cocks from Mexico. First experiment.- Forty cocks were selected on the basis of eggs per gram (EPG) counts quantified by the McMaster method. On day 0 the birds were divided into four groups of 10 cocks, each subjected to the treatments. Group 1 received a single oral dose of 1 mg of ivermectin, 25 mg of praziquantel and 40 mg of fenbendazole given in tablets according to body weight (b.w). Group 2 was treated with a single oral dose of 1 mg of ivermectin, 25 mg of praziquantel and 40 mg of fenbendazole given in tablets/b.w. but formulated with a different excipient. Group 3 received a single tablet containing 0.2 mg of abamectin and 30 mg of albendazole. Group 4 served as a non-treated control. Fecal analyses were carried out on days 0 (day of treatment), 7, 14, 21 and 28, being collected from the floor where the cocks were individually caged. Efficacy was measured on the percentage of egg reduction from day 0 with respect the EPG counts from the control group. In a second experiment the study was similarly performed using another cock-farm located at approximately 300 km away from the first one. Results indicated an overall efficacy of 100%, 94.0% and 100% for groups 1, 2 and 3 in the first experiment and 100%, 100%, 100% for groups 1, 2 and 3 of the 2nd experiment, respectively. It is concluded that all drugs used exerted high efficacy in fighting cocks naturally infected with helminths.

Pleiotrophin fights Brd2 for neuronal differentiation

Bromodomain containing 2 （Brd2） protein belongs to the Bromodomains and Extra Terminal domain （BET） family of chromatin adaptors characterized by the presence of two N-terminal tandem bromodomains and an exclusive C-terminal extra terminal domain （ET） （Belkina and Denis, 2012; Shi and Vakoc, 2014）. Bromodomains are involved in recognizing acetylated histone tails and other acetylated proteins while the ET domain has been implicated in protein-protein interaction.

Effect of Butylated Hydroxytoluene on Survival of Frozen-TIhawed Fighting Bull Spermatozoa

The aim of the present study was to evaluate effect of 3 levels of butylated hydroxytoluene （BHT） supplemented in extender for fighting bull semen. Ejaculates were obtained from 10 healthy fighting bulls by artificial vagina. Semen with motility of more than 70% was included in the experiment. Tris-fructose-glycerol-egg yolk extender containing 0, 1, 3 and 7 mM BHT was used to dilute semen to final concentration of 200 × 10^6 cells/ml. Diluted semen was frozen in 0.25 mL straws and frozen semen was thawed in a 37 ℃ water bath for 15 sec before being evaluated at 0 and 1 hour. Sperm motility at 0 and 1 hour after thawing did not differ among groups tested （ranged 47.86-53.57 and 21.79-24.29 respectively）. At 0 hour after thawing, percentage of live sperm of 3 mM BHT （37.39% ± 2.91%） was lower than those of 0 and 1 mM BHT （43.71%± 2.76% and 41.46% ±2.59% respectively, P 〈 0.05） but not different from 7 mM BHT （40.89%± 2.50%）. The effect was more significant at 1 hour after thawing and 3 mM BHT （32.07% ± 2.45%） suppressed live cells more than other concentrations （ranged 35.07%-37.46%, P 〈 0.05）. At 0 hour after thawing, percentage of membrane integrity （hypo-osmotic swelling test） was not affected by BHT concentration （ranged 23.89%-28.54%）. However, at 1 hour after thawing, percentage of membrane integrity of 3 mM BHT （19.75% ± 1.41%） was lower that of 7 mM BHT （23.29% ± 1.88%, P 〈 0.05） but not different from those of 0 and 1 mM BHT （20.32% ±1.81% and 22.07% ± 2.27% respectively）. No significant effect was found on percentage of abnormal sperm. There was no effect of BHT supplementation in extender on most of the Hamilton-thorn motility analyser parameters. It may be concluded that 3 mM BHT can be harmful to fighting bull spermatozoa and lower concentrmion can be used without detrimental effect. Further study may be needed to verify use of BHT in lower range of concentrations.

Thoughts of a travelling ecologist 10.Will fighting exotics ever succeed?

We live in the Age of Extinctions-the call for naming our time＂Anthropocene＂is no more than hubris and escapism from this colossal sin.Although the6thmass extinction has possibly already started（Barnosky et al.,2011）,and it may prove the largest so far to be endured by life on Earth,efforts are needed not to turn this into the Age of Loneliness,when humans may find themselves Masters of the Earthbut alone（Wilson,2014）.

Deepening Reform of the Supervisory System to Intensify the Fight Against Corruption

FIGHTING against corruption according to the law is a hallmark of China’s anti-corruption campaign since the 18th National Congress of the Communist Party of China(CPC),convened in 2012;and creating a sound,law-based supervisory system is a key focus and task of China’s efforts to establish a system of socialist rule of law with Chinese characteristics and comprehensively advance law-based governance.In 2018,both the government and the CPC stepped up the formulation of laws and Party regulations for the fight against corruption.

Understanding China’s Fight Against Poverty

POVERTY is a common challenge and a major global issue all countries have to face in their economic and social development. Therefore, the fight against poverty is crucial for the progress of human society.