Numerical Treatments for Crossover Cancer Model of Hybrid Variable-Order Fractional Derivatives

In this paper,two crossover hybrid variable-order derivatives of the cancer model are developed.Grünwald-Letnikov approximation is used to approximate the hybrid fractional and variable-order fractional operators.The existence,uniqueness,and stability of the proposed model are discussed.Adams Bashfourth’s fifth-step method with a hybrid variable-order fractional operator is developed to study the proposed models.Comparative studies with generalized fifth-order Runge-Kutta method are given.Numerical examples and comparative studies to verify the applicability of the used methods and to demonstrate the simplicity of these approximations are presented.We have showcased the efficiency of the proposed method and garnered robust empirical support for our theoretical findings.

Modeling Drug Concentration in Blood through Caputo-Fabrizio and Caputo Fractional Derivatives

This study focuses on the dynamics of drug concentration in the blood.In general,the concentration level of a drug in the blood is evaluated by themean of an ordinary and first-order differential equation.More precisely,it is solved through an initial value problem.We proposed a newmodeling technique for studying drug concentration in blood dynamics.This technique is based on two fractional derivatives,namely,Caputo and Caputo-Fabrizio derivatives.We first provided comprehensive and detailed proof of the existence of at least one solution to the problem;we later proved the uniqueness of the existing solution.The proof was written using the Caputo-Fabrizio fractional derivative and some fixed-point techniques.Stability via theUlam-Hyers(UH)technique was also investigated.The application of the proposedmodel on two real data sets revealed that the Caputo derivative wasmore suitable in this study.Indeed,for the first data set,the model based on the Caputo derivative yielded a Mean Squared Error(MSE)of 0.03095 with a corresponding best value of fractional order of derivative of 1.00360.Caputo-Fabrizio-basedderivative appeared to be the second-best method for the problem,with an MSE of 0.04324 for a corresponding best fractional derivative order of 0.43532.For the second experiment,Caputo derivative-based model still performed the best as it yielded an MSE of 0.04066,whereas the classical and the Caputo-Fabrizio methods were tied with the same MSE of 0.07299.Another interesting finding was that the MSE yielded by the Caputo-Fabrizio fractional derivative coincided with the MSE obtained from the classical approach.

Fractional derivative statistical damage model of unsaturated expansive soil based on unified hydraulic effect

Unsaturated expansive soil is widely distributed in China and has complex engineering properties.This paper proposes the unified hydraulic effect shear strength theory of unsaturated expansive soil based on the effective stress principle,swelling force principle,and soil–water characteristics.Considering the viscoelasticity and structural damage of unsaturated expansive soil during loading,a fractional hardening–damage model of unsaturated expansive soil was established.The model parameters were established on the basis of the proposed calculation method of shear strength and the triaxial shear experiment on unsaturated expansive soil.The proposed model was verified by the experimental data and a traditional damage model.The proposed model can satisfactorily describe the entire process of the strain-hardening law of unsaturated expansive soil.Finally,by investigating the damage variables of the proposed model,it was found that:(a)when the values of confining pressure and matric suction are close,the coupling of confining pressure and matric suction contributes more to the shear strength;(b)there is a damage threshold for unsaturated expansive soil,and is mainly reflected by strength criterion of infinitesimal body;(c)the strain hardening law of unsaturated expansive soil is mainly reflected by fractional derivative operator.

Three Kinds of Discrete Formulae for the Caputo Fractional Derivative

In this paper,three kinds of discrete formulae for the Caputo fractional derivative are studied,including the modified L1 discretisation forα∈(O,1),and L2 discretisation and L2C discretisation forα∈(1,2).The truncation error estimates and the properties of the coeffcients of all these discretisations are analysed in more detail.Finally,the theoretical analyses areverifiedby thenumerical examples.

On the Fractional Derivatives with an Exponential Kernel

The present article mainly focuses on the fractional derivatives with an exponential kernel(“exponential fractional derivatives”for brevity).First,several extended integral transforms of the exponential fractional derivatives are proposed,including the Fourier transform and the Laplace transform.Then,the L2 discretisation for the exponential Caputo derivative with a∈(1,2)is established.The estimation of the truncation error and the properties of the coefficients are discussed.In addition,a numerical example is given to verify the correctness of the derived L2 discrete formula.

UNSTEADY FLOWS OF A GENERALIZED SECOND GRADE FLUID WITH THE FRACTIONAL DERIVATIVE MODEL BETWEEN TWO PARALLEL PLATES

The fractional calculus approach in the constitutive relationship model of a generalized second grade fluid is introduced.Exact analytical solutions are obtained for a class of unsteady flows for the generalized second grade fluid with the fractional derivative model between two parallel plates by using the Laplace transform and Fourier transform for fractional calculus.The unsteady flows are generated by the impulsive motion or periodic oscillation of one of the plates.In addition,the solutions of the shear stresses at the plates are also determined.

Hamilton formalism and Noether symmetry for mechanico electrical systems with fractional derivatives

This paper presents extensions to the traditional calculus of variations for mechanico-electrical systems containing fractional derivatives. The Euler Lagrange equations and the Hamilton formalism of the mechanico-electrical systems with fractional derivatives are established. The definition and the criteria for the fractional generalized Noether quasi- symmetry are presented. Furthermore, the fractional Noether theorem and conseved quantities of the systems are obtained by virtue of the invariance of the Hamiltonian action under the infinitesimal transformations. An example is presented to illustrate the application of the results.

Lagrange equations of nonholonomic systems with fractional derivatives

This paper obtains Lagrange equations of nonholonomic systems with fractional derivatives. First, the exchanging relationships between the isochronous variation and the fractional derivatives are derived. Secondly, based on these exchanging relationships, the Hamilton＇s principle is presented for non-conservative systems with fractional derivatives. Thirdly, Lagrange equations of the systems are obtained. Furthermore, the d＇Alembert-Lagrange principle with fractional derivatives is presented, and the Lagrange equations of nonholonomic systems with fractional derivatives are studied. An example is designed to illustrate these results.

Variational Calculus With Conformable Fractional Derivatives

Invariant conditions for conformable fractional problems of the calculus of variations under the presence of external forces in the dynamics are studied. Depending on the type of transformations considered, different necessary conditions of invariance are obtained. As particular cases, we prove fractional versions of Noether's symmetry theorem. Invariant conditions for fractional optimal control problems, using the Hamiltonian formalism, are also investigated. As an example of potential application in Physics, we show that with conformable derivatives it is possible to formulate an Action Principle for particles under frictional forces that is far simpler than the one obtained with classical fractional derivatives.

Analysis of one-dimensional rheological consolidation of double-layered soil with fractional derivative Merchant model and non-Darcian flow described by non-Newtonian index

To further investigate the one-dimensional(1D)rheological consolidation mechanism of double-layered soil,the fractional derivative Merchant model(FDMM)and the non-Darcian flow model with the non-Newtonian index are respectively introduced to describe the deformation of viscoelastic soil and the flow of pore water in the process of consolidation.Accordingly,an 1D rheological consolidation equation of double-layered soil is obtained,and its numerical analysis is performed by the implicit finite difference method.In order to verify its validity,the numerical solutions by the present method for some simplified cases are compared with the results in the related literature.Then,the influence of the revelent parameters on the rheological consolidation of double-layered soil are investigated.Numerical results indicate that the parameters of non-Darcian flow and FDMM of the first soil layer greatly influence the consolidation rate of double-layered soil.As the decrease of relative compressibility or the increase of relative permeability between the lower soil and the upper soil,the dissipation rate of excess pore water pressure and the settlement rate of the ground will be accelerated.Increasing the relative thickness of soil layer with high permeability or low compressibility will also accelerate the consolidation rate of double-layered soil.

Stochastic seismic response of structures with added viscoelastic dampers modeled by fractional derivative

Viscoelastic dampers,as spplementary energy dissipation devices,have been used in building structures un- der seismic excitation or wind loads.Different analytical models have been proposed to describe their dynamic force deform- ation characteristics.Among these analytieal models,the fractional derivative models have attracted more attention as they can capture the frequency dependence of the material stiffness and damping properties observed from tests very well.In this paper,a Fourier-transform-based technique is presented to obtain the fractional unit impulse function and the response of structures with added viscoelastic dampers whose foree-detormation relationship is described by a fractional derivative mod- el.Then,a Duhamel integral-type expression is suggested for the response analysis of a fractional damped dynamie system subjected to deterministic or random excitation.Through numerical verification,it is shown that viscoelastic dampers are ef- fective in reducing structural responses over a wide frequency range,and the proposed schmnes can be used to accurately predict the stochastic seismic response of structures with added viscoelastic dampers described by a Kelvin model wills frac- tional derivative.

Fractional Pfaff-Birkhoff Principle and Birkhoff′s Equations in Terms of Riesz Fractional Derivatives

The dynamical and physical behavior of a complex system can be more accurately described by using the fractional model.With the successful use of fractional calculus in many areas of science and engineering,it is necessary to extend the classical theories and methods of analytical mechanics to the fractional dynamic system.Birkhoffian mechanics is a natural generalization of Hamiltonian mechanics,and its core is the Pfaff-Birkhoff principle and Birkhoff′s equations.The study on the Birkhoffian mechanics is an important developmental direction of modern analytical mechanics.Here,the fractional Pfaff-Birkhoff variational problem is presented and studied.The definitions of fractional derivatives,the formulae for integration by parts and some other preliminaries are firstly given.Secondly,the fractional Pfaff-Birkhoff principle and the fractional Birkhoff′s equations in terms of RieszRiemann-Liouville fractional derivatives and Riesz-Caputo fractional derivatives are presented respectively.Finally,an example is given to illustrate the application of the results.

Non-Noether symmetries of Hamiltonian systems with conformable fractional derivatives

In this paper, we present the fractional Hamilton＇s canonical equations and the fractional non-Noether symmetry of Hamilton systems by the conformable fractional derivative. First/y, the exchanging relationship between isochronous variation and fractional derivatives, and the fractional Hamilton principle of the system under this fractional derivative are proposed. Secondly, the fractional Hamilton＇s canonical equations of Hamilton systems based on the Hamilton principle are established. Thirdly, the fractional non-Noether symmetries, non-Noether theorem and non-Noether conserved quantities for the Hamilton systems with the conformable fractional derivatives are obtained. Finally, an example is given to illustrate the results.

Fractional derivative multivariable grey model for nonstationary sequence and its application

Most of the existing multivariable grey models are based on the 1-order derivative and 1-order accumulation, which makes the parameters unable to be adjusted according to the data characteristics of the actual problems. The results about fractional derivative multivariable grey models are very few at present. In this paper, a multivariable Caputo fractional derivative grey model with convolution integral CFGMC(q, N) is proposed. First, the Caputo fractional difference is used to discretize the model, and the least square method is used to solve the parameters. The orders of accumulations and differential equations are determined by using particle swarm optimization(PSO). Then, the analytical solution of the model is obtained by using the Laplace transform, and the convergence and divergence of series in analytical solutions are also discussed. Finally, the CFGMC(q, N) model is used to predict the municipal solid waste(MSW). Compared with other competition models, the model has the best prediction effect. This study enriches the model form of the multivariable grey model, expands the scope of application, and provides a new idea for the development of fractional derivative grey model.

Stochastic response of van der Pol oscillator with two kinds of fractional derivatives under Gaussian white noise excitation

This paper aims to investigate the stochastic response of the van der Pol （VDP） oscillator with two kinds of fractional derivatives under Gaussian white noise excitation. First, the fractional VDP oscillator is replaced by an equivalent VDP oscillator without fractional derivative terms by using the generalized harmonic balance technique. Then, the stochastic averaging method is applied to the equivalent VDP oscillator to obtain the analytical solution. Finally, the analytical solutions are validated by numerical results from the Monte Carlo simulation of the original fractional VDP oscillator. The numerical results not only demonstrate the accuracy of the proposed approach but also show that the fractional order, the fractional coefficient and the intensity of Gaussian white noise play important roles in the responses of the fractional VDP oscillator. An interesting phenomenon we found is that the effects of the fractional order of two kinds of fractional derivative items on the fractional stochastic systems are totally contrary.

Stochastic bifurcations of generalized Duffing–van der Pol system with fractional derivative under colored noise

The stochastic bifurcation of a generalized Duffing–van der Pol system with fractional derivative under color noise excitation is studied. Firstly, fractional derivative in a form of generalized integral with time-delay is approximated by a set of periodic functions. Based on this work, the stochastic averaging method is applied to obtain the FPK equation and the stationary probability density of the amplitude. After that, the critical parameter conditions of stochastic P-bifurcation are obtained based on the singularity theory. Different types of stationary probability densities of the amplitude are also obtained. The study finds that the change of noise intensity, fractional order, and correlation time will lead to the stochastic bifurcation.

A note on the definition of fractional derivatives applied in rheology

It is known that there exist obivious differences between the two most commonly used definitions of fractional derivatives-Riemann-Liouville （R-L） definition and Caputo definition. The multiple definitions of fractional derivatives in fractional calculus have hindered the application of fractional calculus in rheology. In this paper, we clarify that the R-L definition and Caputo definition are both rheologically imperfect with the help of mechanical analogues of the fractional element model （Scott-Blair model）. We also clarify that to make them perfect rheologically, the lower terminals of both definitions should be put to ∞. We further prove that the R-L definition with lower terminal a →∞ and the Caputo definition with lower terminal a →∞ are equivalent in the differentiation of functions that are smooth enough and functions that have finite number of singular points. Thus we can define the fractional derivatives in rheology as the R-L derivatives with lower terminal a →∞ （or, equivalently, the Caputo derivatives with lower terminal a →∞） not only for steady-state processes, but also for transient processes. Based on the above definition, the problems of composition rules of fractional operators and the initial conditions for fractional differential equations are discussed, respectively. As an example we study a fractional oscillator with Scott-Blair model and give an exact solution of this equation under given initial conditions.

Response of a Duffing-Rayleigh system with a fractional derivative under Gaussian white noise excitation

In this paper,we consider the response analysis of a Duffing-Rayleigh system with fractional derivative under Gaussian white noise excitation.A stochastic averaging procedure for this system is developed by using the generalized harmonic functions.First,the system state is approximated by a diffusive Markov process.Then,the stationary probability densities are derived from the averaged Ito stochastic differential equation of the system.The accuracy of the analytical results is validated by the results from the Monte Carlo simulation of the original system.Moreover,the effects of different system parameters and noise intensity on the response of the system are also discussed.

QUASI-STATIC AND DYNAMICAL ANALYSIS FOR VISCOELASTICTIMOSHENKO BEAM WITH FRACTIONAL DERIVATIVECONSTITUTIVE RELATION

The equations of motion governing the quasi-static and dynamical behavior of a viscoelastic Timoshenko beam are derived. The viscoelastic material is assumed to obey a three-dimensional fractional derivative constitutive relation. ne quasi-static behavior of the viscoelastic Timoshenko beam under step loading is analyzed and the analytical solution is obtained. The influence of material parameters on the deflection is investigated. The dynamical response of the viscoelastic Timoshenko beam subjected to a periodic excitation is studied by means of mode shape functions. And the effect of both transverse shear and rotational inertia on the vibration of the beam is discussed.

An inverse problem to estimate an unknown order of a Riemann-Liouville fractional derivative for a fractional Stokes' first problem for a heated generalized second grade fluid

In this paper,we propose a numerical method to estimate the unknown order of a Riemann-Liouville fractional derivative for a fractional Stokes＇ first problem for a heated generalized second grade fluid.The implicit numerical method is employed to solve the direct problem.For the inverse problem,we first obtain the fractional sensitivity equation by means of the digamma function,and then we propose an efficient numerical method,that is,the Levenberg-Marquardt algorithm based on a fractional derivative,to estimate the unknown order of a Riemann-Liouville fractional derivative.In order to demonstrate the effectiveness of the proposed numerical method,two cases in which the measurement values contain random measurement error or not are considered.The computational results demonstrate that the proposed numerical method could efficiently obtain the optimal estimation of the unknown order of a RiemannLiouville fractional derivative for a fractional Stokes＇ first problem for a heated generalized second grade fluid.