A new cyclodipeptide, cyclo(phenylalanyl-N-methyltyrosyl) 1, was isolated from the mycelial solid cultures of Geotrichum candidum. Its structure was elucidated by spectroscopic methods. The antifungal activity of the ...A new cyclodipeptide, cyclo(phenylalanyl-N-methyltyrosyl) 1, was isolated from the mycelial solid cultures of Geotrichum candidum. Its structure was elucidated by spectroscopic methods. The antifungal activity of the new compound against Peronophythora litchii was assessed by microplate Alamar blue assay (MABA).展开更多
This paper is a report of a 34-year-old man with chronic renal failure undergoing Continuous Ambulatory Peritoneal Dialysis which developed peritonitis due to Geotricum candidum. The diagnosis was established by cultu...This paper is a report of a 34-year-old man with chronic renal failure undergoing Continuous Ambulatory Peritoneal Dialysis which developed peritonitis due to Geotricum candidum. The diagnosis was established by culture of dialysis fluid. The purpose of this report is to provide data on a fungal peritonitis due to a non-common agent.展开更多
A great variety of dairy products with different flavour, texture and health-promoting properties can be obtained from milk using different technologies and starter cultures. Fermented milks are consumed in many parts...A great variety of dairy products with different flavour, texture and health-promoting properties can be obtained from milk using different technologies and starter cultures. Fermented milks are consumed in many parts of the world and are relished for their acidic taste and health benefits. The aim of this study was to compare effects of different ratios of DL-type starter culture： mould Geotrichum candidum grown in milk on its viscosity and sensory properties on the 5th, 10th and 15th day of storage at 4 ~C~ in order to determine the best ratio to prepare fermented milk on basis of Iranian acceptance. We have examined the production of fermented milk by 80： 20, 70： 30, and 60：40 ratios of DL-type starter culture： mould Geotrichum candidum grown in milk. The results obtained from viscosity measurement and sensory evaluation showed no significant difference between these treatments used in the study and were not satisfactory; their viscosity was not accepted and scores attributed to odour and flavor of fermented milks by panelists were low.展开更多
The coevolution and coexistence of bacterial–fungal consortium have been widely reported in various natural ecosystems. The transboundary communication mediated by bacterial acyl–homoserine lactone signals probably ...The coevolution and coexistence of bacterial–fungal consortium have been widely reported in various natural ecosystems. The transboundary communication mediated by bacterial acyl–homoserine lactone signals probably is the driving force of fungal spore germination. This study aimed to report a functional bacterial signal molecule, C10-acyl homoserine lactone, which could be sensed by Galactomyces geotrichum. The spore germination rates of G. geotrichum increased by 22%. Meanwhile, carbohydrate production improved by 1.0-to 2.5-fold. G. geotrichum signaled to C10-HSL through receptor gene Rho1and made a response in cell wall assembly and carbohydrate biosynthesis by the upregulated expression(above 1-fold) of functional genes, such as Smi1, Utr2, and Chs2. It contributed to spore germination and morphology transformation together. This study provides a novel perspective for understating the transboundary cooperation between fungi and bacteria by cell-to-cell communication.展开更多
Bioreduction of some β-carbonyl phenyl sulfides, sulfoxides and sulfones (1, 3, 5, 8, 11 and 13) by Geotrichum sp. was studied. Reduction of β-carbonyl phenyl sulfoxides (5 and 8) gave anti-Prelog sulfoxide alcohols...Bioreduction of some β-carbonyl phenyl sulfides, sulfoxides and sulfones (1, 3, 5, 8, 11 and 13) by Geotrichum sp. was studied. Reduction of β-carbonyl phenyl sulfoxides (5 and 8) gave anti-Prelog sulfoxide alcohols. (S,Ss)-3-Chloro-1-phenylsulfinylpropan-2-ol (9) WBP obtained in high yield with 95% e. e. after recrystallization from methylene chloride petroleum ether.展开更多
文摘A new cyclodipeptide, cyclo(phenylalanyl-N-methyltyrosyl) 1, was isolated from the mycelial solid cultures of Geotrichum candidum. Its structure was elucidated by spectroscopic methods. The antifungal activity of the new compound against Peronophythora litchii was assessed by microplate Alamar blue assay (MABA).
文摘This paper is a report of a 34-year-old man with chronic renal failure undergoing Continuous Ambulatory Peritoneal Dialysis which developed peritonitis due to Geotricum candidum. The diagnosis was established by culture of dialysis fluid. The purpose of this report is to provide data on a fungal peritonitis due to a non-common agent.
文摘A great variety of dairy products with different flavour, texture and health-promoting properties can be obtained from milk using different technologies and starter cultures. Fermented milks are consumed in many parts of the world and are relished for their acidic taste and health benefits. The aim of this study was to compare effects of different ratios of DL-type starter culture： mould Geotrichum candidum grown in milk on its viscosity and sensory properties on the 5th, 10th and 15th day of storage at 4 ~C~ in order to determine the best ratio to prepare fermented milk on basis of Iranian acceptance. We have examined the production of fermented milk by 80： 20, 70： 30, and 60：40 ratios of DL-type starter culture： mould Geotrichum candidum grown in milk. The results obtained from viscosity measurement and sensory evaluation showed no significant difference between these treatments used in the study and were not satisfactory; their viscosity was not accepted and scores attributed to odour and flavor of fermented milks by panelists were low.
基金the National Natural Science Foundation of China (Nos. 52070036, U20A20322)the Fundamental Research Funds for the Central Universities (No. 2412018ZD042) for their financial support。
文摘The coevolution and coexistence of bacterial–fungal consortium have been widely reported in various natural ecosystems. The transboundary communication mediated by bacterial acyl–homoserine lactone signals probably is the driving force of fungal spore germination. This study aimed to report a functional bacterial signal molecule, C10-acyl homoserine lactone, which could be sensed by Galactomyces geotrichum. The spore germination rates of G. geotrichum increased by 22%. Meanwhile, carbohydrate production improved by 1.0-to 2.5-fold. G. geotrichum signaled to C10-HSL through receptor gene Rho1and made a response in cell wall assembly and carbohydrate biosynthesis by the upregulated expression(above 1-fold) of functional genes, such as Smi1, Utr2, and Chs2. It contributed to spore germination and morphology transformation together. This study provides a novel perspective for understating the transboundary cooperation between fungi and bacteria by cell-to-cell communication.
基金Project supported by the National Natural Science Foundation of China (No. 29790125).
文摘Bioreduction of some β-carbonyl phenyl sulfides, sulfoxides and sulfones (1, 3, 5, 8, 11 and 13) by Geotrichum sp. was studied. Reduction of β-carbonyl phenyl sulfoxides (5 and 8) gave anti-Prelog sulfoxide alcohols. (S,Ss)-3-Chloro-1-phenylsulfinylpropan-2-ol (9) WBP obtained in high yield with 95% e. e. after recrystallization from methylene chloride petroleum ether.
