The variability of ocean circulation and sea surface temperature (SST) in the tropical Atlantic, especially in the Gulf of Guinea (GG), defines this region as exceptionally rich from an oceanographic perspective. The ...The variability of ocean circulation and sea surface temperature (SST) in the tropical Atlantic, especially in the Gulf of Guinea (GG), defines this region as exceptionally rich from an oceanographic perspective. The Guinea Current (GC), as the major surface current, plays a significant role in marine productivity and coastal upwelling in the GG. This coastal upwelling is known to influence the climate of the surrounding region, primary productivity and local fisheries. Studies on GC variability and its impact on this coastal upwelling have highlighted that the upwelling downstream of Cape Palmas is influenced by GC detachment, topographic variations and advective processes leading to significant vertical mixing. This study aims to analyze the interannual variability of the GC and its impact on coastal upwelling using the Coastal and Regional Ocean COmmunity model (CROCO). The model’s evaluation is conducted using observational data, specifically Geostrophic and EKman Current Observatory (GEKCO) and Ocean Surface Current Analysis (OSCAR) for currents, and Air-sea Fluxes for the global Tropic ocean-description (TROPFLUX) and Optimum Interpolation-Sea Surface Temperature (OI-SST) for temperature. Thus, the model evaluation indicates that it accurately replicates ocean circulation and SST patterns in the tropical Atlantic and the GG. The joint analysis of upwelling indices (surface and intensity) and the position of the GC core allowed us to conclude that the displacement of the GC core does indeed influence the upwelling indices in the northern part of GG. However, other oceanic and atmospheric mechanisms such as vertical diffusion and horizontal advection as proposed by previous studies may also affect the year-by-year variability of coastal upwelling in the northern GG.展开更多
The main objective of this study was to evaluate the pharmacological potential of the hydroethanol extract of Strychnos camptoneura trunk bark on reproductive functions in male guinea pigs exposed to cypermethrin. The...The main objective of this study was to evaluate the pharmacological potential of the hydroethanol extract of Strychnos camptoneura trunk bark on reproductive functions in male guinea pigs exposed to cypermethrin. The results showed that administration of the hydroethanolic extract (100 and 250 mg/kg) of Strychnos camptoneura trunk bark after exposure of the animals to cypermethrin induced a highly significant (p Strychnos camptoneura trunk bark produced a highly significant (p Strychnos camptoneura trunk bark may have protective effects against cypermethrin-induced male infertility due to its androgenic, spermatogenic and antiradical properties.展开更多
AIM:To quantitatively measure ocular morphological parameters of guinea pig with Python technology.METHODS:Thirty-six eyeballs of eighteen 3-weekold guinea pigs were measured with keratometer and photographed to obtai...AIM:To quantitatively measure ocular morphological parameters of guinea pig with Python technology.METHODS:Thirty-six eyeballs of eighteen 3-weekold guinea pigs were measured with keratometer and photographed to obtain the horizontal,coronal,and sagittal planes respectively.The corresponding photo pixels-actual length ratio was acquired by a proportional scale.The edge coordinates were identified artificially by ginput function.Circle and conic curve fitting were applied to fit the contour of the eyeball in the sagittal,coronal and horizontal view.The curvature,curvature radius,eccentricity,tilt angle,corneal diameter,and binocular separation angle were calculated according to the geometric principles.Next,the eyeballs were removed,canny edge detection was applied to identify the contour of eyeball in vitro.The results were compared between in vivo and in vitro.RESULTS:Regarding the corneal curvature and curvature radius on the horizontal and sagittal planes,no significant differences were observed among results in vivo,in vitro,and the keratometer.The horizontal and vertical binocular separation angles were 130.6°±6.39°and 129.8°±9.58°respectively.For the corneal curvature radius and eccentricity in vivo,significant differences were observed between horizontal and vertical planes.CONCLUSION:The Graphical interface window of Python makes up the deficiency of edge detection,which requires too much definition in Matlab.There are significant differences between guinea pig and human beings,such as exotropic eye position,oblique oval eyeball,and obvious discrepancy of binoculus.This study helps evaluate objectively the ocular morphological parameters of small experimental animals in emmetropization research.展开更多
Blood transfusion saves lives and reduces morbidity and mortality for a large number of diseases and clinical conditions, but it is not without danger. The aim of this study was to determine the seroprevalence of HIV ...Blood transfusion saves lives and reduces morbidity and mortality for a large number of diseases and clinical conditions, but it is not without danger. The aim of this study was to determine the seroprevalence of HIV and hepatitis B in blood donors received at the regional Blood Transfusion Centre of N’Zérékoré (Guinea). This was a 5-year retrospective analytical study. We included records of blood donors aged 18 to 60 years admitted to the N’Zérékoré Regional Blood Transfusion Centre for blood donation from January 2016 to December 2020. We performed a descriptive analysis followed by Chi-2 or Fish-er-exact tests and the Student or Wilcoxon test, followed by multivariate logistic regression. In this study, donor age ranged from 18 - 60 years, with a pre-dominance of donors aged 25 - 34 (44.2%). Male donors were the most represented in our study (79.0% versus 21.0% female). More than half of the donors were blood group O (55.6%). We observed a seroprevalence of 3.6% for HIV, 13.4% for HBsAg and 0.2% for co-infection. In our series, age 25 - 34 (OR = 1.89 and P = 0.001) and 35 - 44 for HIV (OR = 2.01 and P = 0.001), HBsAgserostatus (OR = 3.04 and P = 0.001) and blood donation history (OR of 3.04 and P = 0.001) were factors associated with HIV positivity (P < 0.05). In our study, HIV serostatus (OR = 3.04 and P = 0.001) and blood donation history (OR = 0.01 and P = 0.001) were factors associated with HBsAgseropositivity. We reported a high prevalence of HIV and HBsAg. Sex, serological status and blood donation history were associated factors.展开更多
The antiretroviral treatment (ART) has significantly reduced the number of new HIV/AIDS infections and related deaths. However, cases of immunovirological discordance (IVD) are found in various locations. The objectiv...The antiretroviral treatment (ART) has significantly reduced the number of new HIV/AIDS infections and related deaths. However, cases of immunovirological discordance (IVD) are found in various locations. The objective of this study was to determine the profile of People living with HIV (PLHIV) with IVD and to identify associated factors. We conducted a cross-sectional study based on the records of PLHIV under ART for at least 6 months, followed at Hpital de Jour Donka from 2015 to 2017, and having both viral load (CV) and CD4 T-cell count. Prevalence of IVD was 34.57%, with 23.87% for immunological discordance (ID) and 10.7% for virological discordance (VD). Females were predominant (66.26%), and male gender influenced IVD with a statistically significant difference (p = 0.006) and was associated with VD (p = 0.007). The average age was 38.77 11.30 years. PLHIV were classified at WHO stages 3 and 4 (86.01%). The median initial haemoglobin level was 11.5 g/L [3.2 - 12]. The mean initial CD4 T-cell count was 272.84 cells/mm3 201.6. The median initial viral load (VL) was 147,337 copies/mL [1092 - 31,675,000]. The initial CD4 T-cell count 3 was associated with IVD with a statistically significant difference (p = 0.0009) and correlated with ID (p = 0.000). Prurigo was associated with IVD with a statistically significant difference (p = 0.003). Cerebral toxoplasmosis was not associated with IVD but was associated with ID (p = 0.04). This study allowed us to describe the profile of PLHIV with IVD. The main associated factors were male gender, initial CD4 T-cell count 3, toxoplasmosis, prurigo, and herpes zoster.展开更多
As part of the national strategy to further develop the wind energy sector,the eight prefectures of Upper Guinea have been selected.Using meteorological data recorded over thirty years(1991-2021)at a height of 20 m,we...As part of the national strategy to further develop the wind energy sector,the eight prefectures of Upper Guinea have been selected.Using meteorological data recorded over thirty years(1991-2021)at a height of 20 m,we assessed wind resources in terms of characteristic speeds,power and available energy.To this end,the Weibull distribution method was used and the following values were obtained:3.66 m/s for the average speed;1,102.83 W/m^(2)for the available power and 8,747.06 kWh/m^(2)/year for the annual available energy.展开更多
Introduction: Corticosteroid therapy used in rheumatology is effective but can lead to complications. The objective was to describe the complications of corticosteroid therapy in rheumatological practice at Ignace Dee...Introduction: Corticosteroid therapy used in rheumatology is effective but can lead to complications. The objective was to describe the complications of corticosteroid therapy in rheumatological practice at Ignace Deen University Hospital (Conakry). Methods: Cross-sectional study from July 1, 2022 to March 31, 2023. All patients who had been diagnosed with a rheumatological disease and who had received corticosteroid therapy were included. Results: Of the 1489 patients suffering from rheumatological diseases, 238 (15.9%) had received corticosteroid therapy. The average age of the patients was 48.5 ± 17.16 years with a female predominance (70.5%). The main indications for corticosteroid therapy were lower back pain due to probable disco-radicular impingement (35.8%) followed by rheumatoid arthritis (21.9%). The predominant method of administration was infiltration (56.9%). The average dosage was 24.2 ± 13.5 mg prednisone equivalent (range: 5 mg and 40 mg). Complications were present in 26 patients (10.9%) such as muscle cramps (3.8%), hypocalcemia (3.4%), edema of the lower limbs (3%), stimulation of appetite and weight gain (3%), high blood pressure (2.5%), hyperglycemia (2.5%). The occurrence of complications was associated with the high dose of corticosteroid (p = 0.014) and long-term use (p = 0.000). Conclusion: Corticosteroid therapy used in 15.9% of consultations in the rheumatology department of Ignace Deen University Hospital led to 10.9% of complications. These complications were related to the dose and duration of corticosteroid therapy.展开更多
Introduction: Cystic lymphangiomas are rare benign malformative tumors of the lymphatic system of obscure etiopathogenesis. The cervico-facial location remains the most common (75%). Although benign, these tumors rema...Introduction: Cystic lymphangiomas are rare benign malformative tumors of the lymphatic system of obscure etiopathogenesis. The cervico-facial location remains the most common (75%). Although benign, these tumors remain potentially fatal, due to possible compression of the upper aero-digestive tract. The aim of this work is to study the epidemiological, diagnostic and therapeutic characteristics of cervico-mandibular congenital cystic lymphangiomas in the pediatric surgery department of the Donka National Hospital (HND) Conakry. Patients and methods: This is a retrospective and descriptive study of 13 files lasting 7 years from January 2015 to December 31, 2021. The files of children whose age is less than or equal to 15 years operated on cervical tumor with histological evidence of cystic lymphangioma were retained. The data were analyzed using SPSS statistical software 21 and anonymously. Results: The incidence of this study was 1.86 cases per year and a sex ratio of 0.62 in favor of girls. The average age was 8 months 19 days. In the antecedents, we only find poorly monitored pregnancies. The average size of the tumors was 11.85 cm. Cervical ultrasound and standard x-ray of the cervical mass were the only examinations performed. Total surgical excision of the cervical tumor was performed in all patients. The mass was polycystic on exploration. The histological examination of the surgical specimens was in favor of a cystic lymphangioma. The surgical consequences were simple in 11 patients (84.62%) and complicated by parietal suppuration in 2 cases (15.38%). There were no cases of recurrence after one year of follow-up. Conclusion: Cervico-mandibular cystic lymphangiomas are the most frequent locations of congenital lymphangiomas in children. Their severity is linked to the risk of compression of the aero-digestive tracts. Their diagnosis must be confirmed by the histology of the surgical specimen. Despite the therapeutic arsenal, excision of the cystic mass remains the only effective alternative in our socio-economic conditions to avoid recurrences and loss of follow-up of patients.展开更多
With the arrival of the 4G and 5G,the telecommunications networks have experienced a large expansion of these networks.That enabled the integration of many services and adequate flow,thus enabling the operators to res...With the arrival of the 4G and 5G,the telecommunications networks have experienced a large expansion of these networks.That enabled the integration of many services and adequate flow,thus enabling the operators to respond to the growing demand of users.This rapid evolution has given the operators to adapt,their methods to the new technologies that increase.This complexity becomes more important,when these networks include several technologies to access different from the heterogeneous network like in the 4G network.The dimensional new challenges tell the application and the considerable increase in demand for services and the compatibility with existing networks,the management of mobility intercellular of users and it offers a better quality of services.Thus,the proposed solution to meet these new requirements is the sizing of the EPC(Evolved Packet Core)core network to support the 5G access network.For the case of Orange Guinea,this involves setting up an architecture for interconnecting the core networks of Sonfonia and Camayenne.The objectives of our work are of two orders:(1)to propose these solutions and recommendations for the heart network EPC sizing and the deployment to be adopted;(2)supply and architectural interconnection in the heart network EPC and an existing heart network.In our work,the model of traffic in communication that we use to calculate the traffic generated with each technology has link in the network of the heart.展开更多
Introduction: The birth of a baby is a moment of joy and celebration. However, the neonatal period is a very delicate phase of life. Neonatal mortality rates remain high in low-income countries. In Guinea, after 20 ye...Introduction: The birth of a baby is a moment of joy and celebration. However, the neonatal period is a very delicate phase of life. Neonatal mortality rates remain high in low-income countries. In Guinea, after 20 years, this rate has fallen from 34.2% in 1998 to 32% in 2018. Objective: To identify the main risk factors for neonatal mortality. Methods: This was an observational, analytical case-control study, lasting 6 months from January 1 to June 30, 2019, conducted at the Institut de Nutrition et de la Santé de l’Enfant (INSE) at Donka National Hospital. Results: We collected 242 cases and 242 controls, i.e. a total of 484 records. 748 patients were registered, with 32.35% deaths. 82.86% of deaths occurred in the early neonatal period. Statistical analysis revealed the main risk factors: prematurity (RQ 7.39 95% CI 3.27 - 16.61 p = 0.0000003), hypothermia (RQ 2.29 95% CI 1.51 - 3.46 p = 0.0001), acute fetal distress (RQ 2.13 95% CI 1.33 - 3.43 p = 0.0016), low birth weight (QR 1.91 95% CI 1.12 - 3.24 p = 0.016), home birth (QR 3.26 95% CI 1.25 - 8.46 p = 0.015). Conclusion: Neonatal mortality is a health problem in the INSE neonatology department. To reduce the mortality rate in this referral facility, it is essential to equip it and provide ongoing training for staff.展开更多
The purpose of this work is to assess wind potential on the Kanfarandé site (Guinea). The data used for this research covers a period of 6 years (2018 to 2023) and consists of in situ data (Boké meteorologic...The purpose of this work is to assess wind potential on the Kanfarandé site (Guinea). The data used for this research covers a period of 6 years (2018 to 2023) and consists of in situ data (Boké meteorological station) and satellite products via NASA Power Larc. The study is based on sorted hourly data (speed and direction). The treatments focus on the monthly, annual and seasonal average of speeds, by sector and their frequencies as well as the annual available powers. The obtained results made it possible, on the one hand, to assess wind potential and, on the other hand, to highlight the most favorable periods for wind energy exploitation. The analyzes show the months of July and August have the best average wind speeds with 5.01 m/s and 5.34 m/s respectively. Average wind speeds are higher during the day than at night with a peak observed at 6 p.m. The study also shows that the prevailing winds are oriented towards the South-West. The Weibull parameters determined for the site give an average of 4.5 m/s for the scale parameter and for the shape parameter 2.40 corresponding to an average power density of 65 w/m2 with an annual available power of 194.80 W/m2 and an annual available energy of 1706.45 kWh/m2.展开更多
Leafhoppers (jassids) are well-known pests of vegetable crops in Niger. They are often part of a parasitic complex that causes varying degrees of damage. Over the last two crop years, the Niamey region has seen a heav...Leafhoppers (jassids) are well-known pests of vegetable crops in Niger. They are often part of a parasitic complex that causes varying degrees of damage. Over the last two crop years, the Niamey region has seen a heavy outbreak of leaf hoppers on okra and guinea sorrel. These insects alone have caused spectacular damage, resulting in losses ranging from 50% to 100% of unharvested plants. Following this observation, infested fields were surveyed, specimens sampled, and the responsible species identified. Two sites were surveyed in the city of Niamey. At each site, two plots of okra and two of guinea sorrel were visited. Fifty (50) plants were randomly sampled using the double “W” method per plot. The sampled plants were used for active and passive leaf hopper capture, damage description and loss assessment. Captured leaf hoppers were identified based on their morphology observed with a binocular magnifying glass and compared with the data in the identification keys. The symptoms observed in the plots were yellowing, leaf curling and drying, stunting, abortion of flowers and immature fruit and very low production. Identification results revealed the single species Amrasca biguttula (Ishida, 1913), which can be considered a new invasive species in Niger. Further confirmation of this identification by molecular tests, the distribution of the pest in Niger and the development of appropriate control methods would yield good prospects.展开更多
This article looks at the developments of computing in Papua New Guinea (PNG) in the post-independence era. More specifically, this article examines the development of national policies on Information and Communicatio...This article looks at the developments of computing in Papua New Guinea (PNG) in the post-independence era. More specifically, this article examines the development of national policies on Information and Communications Technology (ICT), digital technologies in PNG, and the development of computing education in PNG since 1975. The research findings reveal that PNG has made solid progress in computing, ICT, national ICT policies, digital technologies, and computing education at universities in the post-independence era. The proposed approach in this article might facilitate the research and development of computing, ICT, digital technologies, and big data analytics in PNG, and beyond.展开更多
Each year, rabies kills nearly 60,000 people worldwide. Asia and Africa are the most affected. It is a public health problem because of the number of stray dogs in these nations. In Guinea, rabies is endemic and cases...Each year, rabies kills nearly 60,000 people worldwide. Asia and Africa are the most affected. It is a public health problem because of the number of stray dogs in these nations. In Guinea, rabies is endemic and cases are often under-reported. The objective of this study was to determine the prevalence of rabies among human and animal exposures in Guinea. This was a retrospective analytical study from 2019 to 2021 conducted in the country’s human and veterinary health divisions and, primarily focused on rabies épidémiologique surveillance. The selection was based on human contact with an animal causing behavioural disorders, as well as animals put under observation following aggression on humans. The data were analysed using Epi Info version 21 software. Qualitative variables were expressed as proportions with 95% CIs, quantitative variables as mean ± standard deviation. The chi2 test and the Fischer exact test were used to compare proportions. A total of 85 veterinary facilities were visited and 100 animals registered, of which 93% were reported cases of exposure to canine rabies. One thousand five hundred and thirty-one (1531) people exposed to rabies were recorded between 2019 and 2021. During the period, the prevalence of human rabies was 0.533% [0.042 - 0.064] at 95% CI and that of canine rabies was 0.55% [0.039 - 0.061] at 95% CI. The biting animal was the dog in 97.2% of cases. Subjects over 45 years of age (57.7%) were the most affected. The prevalence of canine rabies was 0.5% compared with 0.533% for human rabies between 2019 and 2021. This low prevalence does not reflect the true extent of the phenomenon in Guinea, as few people consult health structures in the event of dog bites. Regular surveillance of the human and dog population is necessary for better rabies control in Guinea.展开更多
The chemical and mineralogical composition of bauxite deposits is a key factor in the profitability of refining processes. The study of bauxites from the Saföfö site has assessed variations in chemical and m...The chemical and mineralogical composition of bauxite deposits is a key factor in the profitability of refining processes. The study of bauxites from the Saföfö site has assessed variations in chemical and mineralogical composition under various conditions, as well as the optimum conditions for their exploitation. The methodologies used in this study include experimental methods for determining moisture content, chemical composition, mineralogical composition, and specific density of bauxite. The results show significant variation in moisture content among the bauxite samples, with values ranging from 2.90% to 17.80%. The silica percentages in the samples range from 1.69% to 8.14%, while alumina percentages vary from 36.81% to 54.03%. After calcination, alumina oxide percentages range from 40% to 75%. After chemical activation, alumina oxides Al2O3 range from 40% to over 50%. Gibbsite is the most abundant mineral, accounting for about 60% - 70% of the total composition of the bauxite samples. Samples A to F have bulk densities varying between approximately 3.6 and 3.9. Sample B has the highest density, around 3.9, while sample C has the lowest, at around 3.5. Bauxite mining at the Saföfö site offers significant potential for the alumina industry, provided appropriate processing methods are selected to maximize quality and profitability while minimizing environmental impact.展开更多
AIM:To investigate the effect of electroacupuncture(EA)on the mitochondria-dependent apoptotic signaling pathway in the ciliary muscle of guinea pigs with negative lensinduced myopia(LIM).METHODS:Guinea pigs were rand...AIM:To investigate the effect of electroacupuncture(EA)on the mitochondria-dependent apoptotic signaling pathway in the ciliary muscle of guinea pigs with negative lensinduced myopia(LIM).METHODS:Guinea pigs were randomly divided into normal control(NC)group,LIM group,LIM+SHAM acupoint(LIM+SHAM)group,and LIM+EA group.Animals in the NC group received no intervention,while those in other three groups were covered with-6.0 diopter(D)lenses on right eyes.Meanwhile,animals in the LIM+EA group received EA at Hegu(LI4)combined with Taiyang(EX-HN5)acupoints,while those in the LIM+SHAM group were treated at sham points.After treatments for 1,2,and 4wk,morphological changes in ciliary muscles were observed with hematoxylin and eosin(H&E)staining and nick end labeling(TUNEL),and the expression of the mitochondrial apoptotic signaling pathway-related molecules in ciliary muscles was measured by real-time quantitative polymerase chain reaction(qPCR)and Western blot.Additionally,the adenosine triphosphate(ATP)contents were also determined in ciliary muscles.RESULTS:Axial length increased significantly in the LIM and LIM+SHAM groups and decreased in the LIM+EA group.The ciliary muscle fibers were broken and destroyed in both LIM and LIM+SHAM groups,whereas those in the LIM+EA group improved significantly.TUNEL assay showed the number of apoptotic cells increased in the LIM and LIM+SHAM groups,whereas reduced in the LIM+EA group.ATP contents showed a significant decrease in the LIM and LIM+SHAM groups,whereas increased after EA treatment.Compared with the NC group,the dynamin-related protein 1(DRP1),Caspase3,and apoptotic protease activator 1(APAF1)levels were significantly increased in the LIM group and decreased in the LIM+EA group.CONCLUSION:The results provide evidence of EA inhibiting the development of myopia by regulating the mitochondrial apoptotic signaling pathway.展开更多
Waves play a major role in the ocean phenomena in the Gulf of Guinea(GoG). In order to reveal the spatial-temporal distribution characteristics and the propagation mechanism of waves from the South Atlantic Ocean to t...Waves play a major role in the ocean phenomena in the Gulf of Guinea(GoG). In order to reveal the spatial-temporal distribution characteristics and the propagation mechanism of waves from the South Atlantic Ocean to the GoG, 4typical points located in mid-latitude of South Atlantic(14°30′W, 30°0′S), south of the GoG(10°30′W, 15°0′S), offshore of the GoG(0°0′, 0°0′) and near shore of the GoG(6°4′58.8″W, 4°3′36″S) are selected, and waves from Atlantic Ocean to GoG are simulated by using a two-layer-nesting wave numerical model SWAN(Simulating Waves Nearshore). The results show that the hybrid waves(waves hereafter) and the swells have strong relationship with local wind in Roaring Forties and at mid-latitude of South Atlantic Ocean, while there is no obvious correlation between waves and local winds in the GoG. Swells are generated in the South Atlantic Ocean and propagate into the GoG. 2D wave spectra at the four selected typical points are simulated. The spectral pattern and wave component structure indicate that the wave system in GoG is dominated by the S-SW swells generated from Roaring Forties and mid-latitude of South Atlantic, whether it is at maximum(2.2-2.8 m), medium(1.8-2.2 m) or minimum(1.2 m) significant wave height in the GoG during simulation period.展开更多
Ebstein’s anomaly is a rare congenital heart disease. We report a series of 4 cases of Ebstein’s anomaly discovered in adolescents. The mean age was 13.75 ± 0.96, with 3 boys and one girl. Three ...Ebstein’s anomaly is a rare congenital heart disease. We report a series of 4 cases of Ebstein’s anomaly discovered in adolescents. The mean age was 13.75 ± 0.96, with 3 boys and one girl. Three were in heart failure. The EKG showed atrial hypertrophy (1 case), right bundle branch block (1 case), Wolff-Parkinson-White (1 case), and atrial fibrillation (1 case). Cardiomegaly was present in all patients with a mean cardiothoracic index of 0.77 ± 0.03. On echocardiography, the mean apical displacement of the tricuspid septal leaflet was 22.5 ± 3.30 mm/m<sup>2</sup>, the Celermajer index was Grade 2 in 2 patients and Grade 4 in 2 patients. Depletive medical treatment was prescribed to 3 patients. Anticoagulant therapy was initiated in one patient. Two are awaiting surgery. One death was recorded, it was at Grade 4 of the Celermajer index.展开更多
The impacts of climate change on crop yields are receiving renewed interest,with focus on cereals and staple crops at the regional and national scales.Yet,the impacts of climate change on the yields of leguminous crop...The impacts of climate change on crop yields are receiving renewed interest,with focus on cereals and staple crops at the regional and national scales.Yet,the impacts of climate change on the yields of leguminous crops in the local context has not been explored.Thus,an in-depth understanding of climate change in the local context may support the design of locally relevant adaptation responses to current and future climate risks.This study examined the impacts of climate variables(annual rainfall,annual average temperature,rainfall indices(rainfall onset,rainfall cessation,and the length of rainy days),and the number of dry days)on the yields of leguminous crops(groundnuts,cowpeas,and soybeans)in the Guinea Savanna agroecological zone of Ghana during the period of 1989-2020.The data were analysed using Mann-Kendall’s trend,Sen’s slope test,correlation analysis,and Multiple Regression Analysis(MRA).The findings revealed that annual rainfall,annual average temperature,rainfall onset,rainfall cessation,and the length of rainy days,and the number of dry days all showed varied impacts on the yields of groundnuts,cowpeas,and soybeans.The trend analysis detected a marginal decrease in the amount of rainfall,rainfall onset,and the number of dry days from 1989 to 2020(P>0.050).Annual average temperature and the length of rainy days substantially varied(P<0.050)from 1989 to 2020,showing an increasing trend.The findings also showed a marked upward trend for the yields of groundnuts,cowpeas,and soybeans during 2005-2020.The climate variables analysed above increased the yields of groundnuts,cowpeas,and soybeans by 49.0%,55.0%,and 69.0%,respectively.The yields of groundnuts,cowpeas,and soybeans fluctuated with the variability of 30.0%,28.0%,and 27.0%from 2005 to 2020,respectively.The three leguminous crops under study demonstrated unpredictable yields due to the variations of annual rainfall,annual average temperature,rainfall onset,rainfall cessation,the length of rainy days,and the number of dry days,which stressed the need for agricultural diversification,changing planting dates,using improved seed variety,and irrigation to respond to climate change.The results of this study implied that climate change considerably impacts crop production in the Guinea Savanna agroecological zone of Ghana,emphasizing the urgency of locally based and farmer-induced adaptation measures for food security and resilient agricultural systems.展开更多
Introduction: Unmet need for family planning (UNFP) is defined as women with unmet needs who want to stop or delay childbearing but are not using any method of contraception. The objective of this study was to analyze...Introduction: Unmet need for family planning (UNFP) is defined as women with unmet needs who want to stop or delay childbearing but are not using any method of contraception. The objective of this study was to analyze the factors associated with unmet needs for family planning among couples living in rural and urban areas of Guinea in 2019. Methodology: This was a prospective, analytical cross-sectional, multicenter study of a six-month period from August 1, 2018 to January 31, 2019, focusing on couples with unmet needs for family planning. Result: Among 189 couples interviewed, 567 had UNFP (33.3%), the reasons for not using modern contraceptive methods were desire for pregnancy (AOR = 2.74, 95% CI: 1.74, 4.31), husband’s refusal (AOR = 0.23, 95% CI: 0.06, 0.81), spousal attitude (AOR = 0.20, 95% CI: 0.130, 30), birth spacing (AOR = 2.10% to 95%: 1.16, 3.82), difficulty with a new pregnancy (AOR = 0.17, 95% CI: 0.04, 0.74), and spousal attitude (AOR = 0.20, 95% CI: 0.14, 0.30). Conclusion: The involvement of spouses, especially in rural communities, would help achieve family planning objectives and reduce unmet needs for family planning.展开更多
文摘The variability of ocean circulation and sea surface temperature (SST) in the tropical Atlantic, especially in the Gulf of Guinea (GG), defines this region as exceptionally rich from an oceanographic perspective. The Guinea Current (GC), as the major surface current, plays a significant role in marine productivity and coastal upwelling in the GG. This coastal upwelling is known to influence the climate of the surrounding region, primary productivity and local fisheries. Studies on GC variability and its impact on this coastal upwelling have highlighted that the upwelling downstream of Cape Palmas is influenced by GC detachment, topographic variations and advective processes leading to significant vertical mixing. This study aims to analyze the interannual variability of the GC and its impact on coastal upwelling using the Coastal and Regional Ocean COmmunity model (CROCO). The model’s evaluation is conducted using observational data, specifically Geostrophic and EKman Current Observatory (GEKCO) and Ocean Surface Current Analysis (OSCAR) for currents, and Air-sea Fluxes for the global Tropic ocean-description (TROPFLUX) and Optimum Interpolation-Sea Surface Temperature (OI-SST) for temperature. Thus, the model evaluation indicates that it accurately replicates ocean circulation and SST patterns in the tropical Atlantic and the GG. The joint analysis of upwelling indices (surface and intensity) and the position of the GC core allowed us to conclude that the displacement of the GC core does indeed influence the upwelling indices in the northern part of GG. However, other oceanic and atmospheric mechanisms such as vertical diffusion and horizontal advection as proposed by previous studies may also affect the year-by-year variability of coastal upwelling in the northern GG.
文摘The main objective of this study was to evaluate the pharmacological potential of the hydroethanol extract of Strychnos camptoneura trunk bark on reproductive functions in male guinea pigs exposed to cypermethrin. The results showed that administration of the hydroethanolic extract (100 and 250 mg/kg) of Strychnos camptoneura trunk bark after exposure of the animals to cypermethrin induced a highly significant (p Strychnos camptoneura trunk bark produced a highly significant (p Strychnos camptoneura trunk bark may have protective effects against cypermethrin-induced male infertility due to its androgenic, spermatogenic and antiradical properties.
基金Supported by the National Natural Science Foundation of China(No.81400428)Self-selected Projects of Shanghai Children’s Hospital(No.2020R124)Shanghai Children’s Hospital Hospital-level Project Clinical Research Cultivation Special Focus Project(No.2021YLYZ03).
文摘AIM:To quantitatively measure ocular morphological parameters of guinea pig with Python technology.METHODS:Thirty-six eyeballs of eighteen 3-weekold guinea pigs were measured with keratometer and photographed to obtain the horizontal,coronal,and sagittal planes respectively.The corresponding photo pixels-actual length ratio was acquired by a proportional scale.The edge coordinates were identified artificially by ginput function.Circle and conic curve fitting were applied to fit the contour of the eyeball in the sagittal,coronal and horizontal view.The curvature,curvature radius,eccentricity,tilt angle,corneal diameter,and binocular separation angle were calculated according to the geometric principles.Next,the eyeballs were removed,canny edge detection was applied to identify the contour of eyeball in vitro.The results were compared between in vivo and in vitro.RESULTS:Regarding the corneal curvature and curvature radius on the horizontal and sagittal planes,no significant differences were observed among results in vivo,in vitro,and the keratometer.The horizontal and vertical binocular separation angles were 130.6°±6.39°and 129.8°±9.58°respectively.For the corneal curvature radius and eccentricity in vivo,significant differences were observed between horizontal and vertical planes.CONCLUSION:The Graphical interface window of Python makes up the deficiency of edge detection,which requires too much definition in Matlab.There are significant differences between guinea pig and human beings,such as exotropic eye position,oblique oval eyeball,and obvious discrepancy of binoculus.This study helps evaluate objectively the ocular morphological parameters of small experimental animals in emmetropization research.
文摘Blood transfusion saves lives and reduces morbidity and mortality for a large number of diseases and clinical conditions, but it is not without danger. The aim of this study was to determine the seroprevalence of HIV and hepatitis B in blood donors received at the regional Blood Transfusion Centre of N’Zérékoré (Guinea). This was a 5-year retrospective analytical study. We included records of blood donors aged 18 to 60 years admitted to the N’Zérékoré Regional Blood Transfusion Centre for blood donation from January 2016 to December 2020. We performed a descriptive analysis followed by Chi-2 or Fish-er-exact tests and the Student or Wilcoxon test, followed by multivariate logistic regression. In this study, donor age ranged from 18 - 60 years, with a pre-dominance of donors aged 25 - 34 (44.2%). Male donors were the most represented in our study (79.0% versus 21.0% female). More than half of the donors were blood group O (55.6%). We observed a seroprevalence of 3.6% for HIV, 13.4% for HBsAg and 0.2% for co-infection. In our series, age 25 - 34 (OR = 1.89 and P = 0.001) and 35 - 44 for HIV (OR = 2.01 and P = 0.001), HBsAgserostatus (OR = 3.04 and P = 0.001) and blood donation history (OR of 3.04 and P = 0.001) were factors associated with HIV positivity (P < 0.05). In our study, HIV serostatus (OR = 3.04 and P = 0.001) and blood donation history (OR = 0.01 and P = 0.001) were factors associated with HBsAgseropositivity. We reported a high prevalence of HIV and HBsAg. Sex, serological status and blood donation history were associated factors.
文摘The antiretroviral treatment (ART) has significantly reduced the number of new HIV/AIDS infections and related deaths. However, cases of immunovirological discordance (IVD) are found in various locations. The objective of this study was to determine the profile of People living with HIV (PLHIV) with IVD and to identify associated factors. We conducted a cross-sectional study based on the records of PLHIV under ART for at least 6 months, followed at Hpital de Jour Donka from 2015 to 2017, and having both viral load (CV) and CD4 T-cell count. Prevalence of IVD was 34.57%, with 23.87% for immunological discordance (ID) and 10.7% for virological discordance (VD). Females were predominant (66.26%), and male gender influenced IVD with a statistically significant difference (p = 0.006) and was associated with VD (p = 0.007). The average age was 38.77 11.30 years. PLHIV were classified at WHO stages 3 and 4 (86.01%). The median initial haemoglobin level was 11.5 g/L [3.2 - 12]. The mean initial CD4 T-cell count was 272.84 cells/mm3 201.6. The median initial viral load (VL) was 147,337 copies/mL [1092 - 31,675,000]. The initial CD4 T-cell count 3 was associated with IVD with a statistically significant difference (p = 0.0009) and correlated with ID (p = 0.000). Prurigo was associated with IVD with a statistically significant difference (p = 0.003). Cerebral toxoplasmosis was not associated with IVD but was associated with ID (p = 0.04). This study allowed us to describe the profile of PLHIV with IVD. The main associated factors were male gender, initial CD4 T-cell count 3, toxoplasmosis, prurigo, and herpes zoster.
文摘As part of the national strategy to further develop the wind energy sector,the eight prefectures of Upper Guinea have been selected.Using meteorological data recorded over thirty years(1991-2021)at a height of 20 m,we assessed wind resources in terms of characteristic speeds,power and available energy.To this end,the Weibull distribution method was used and the following values were obtained:3.66 m/s for the average speed;1,102.83 W/m^(2)for the available power and 8,747.06 kWh/m^(2)/year for the annual available energy.
文摘Introduction: Corticosteroid therapy used in rheumatology is effective but can lead to complications. The objective was to describe the complications of corticosteroid therapy in rheumatological practice at Ignace Deen University Hospital (Conakry). Methods: Cross-sectional study from July 1, 2022 to March 31, 2023. All patients who had been diagnosed with a rheumatological disease and who had received corticosteroid therapy were included. Results: Of the 1489 patients suffering from rheumatological diseases, 238 (15.9%) had received corticosteroid therapy. The average age of the patients was 48.5 ± 17.16 years with a female predominance (70.5%). The main indications for corticosteroid therapy were lower back pain due to probable disco-radicular impingement (35.8%) followed by rheumatoid arthritis (21.9%). The predominant method of administration was infiltration (56.9%). The average dosage was 24.2 ± 13.5 mg prednisone equivalent (range: 5 mg and 40 mg). Complications were present in 26 patients (10.9%) such as muscle cramps (3.8%), hypocalcemia (3.4%), edema of the lower limbs (3%), stimulation of appetite and weight gain (3%), high blood pressure (2.5%), hyperglycemia (2.5%). The occurrence of complications was associated with the high dose of corticosteroid (p = 0.014) and long-term use (p = 0.000). Conclusion: Corticosteroid therapy used in 15.9% of consultations in the rheumatology department of Ignace Deen University Hospital led to 10.9% of complications. These complications were related to the dose and duration of corticosteroid therapy.
文摘Introduction: Cystic lymphangiomas are rare benign malformative tumors of the lymphatic system of obscure etiopathogenesis. The cervico-facial location remains the most common (75%). Although benign, these tumors remain potentially fatal, due to possible compression of the upper aero-digestive tract. The aim of this work is to study the epidemiological, diagnostic and therapeutic characteristics of cervico-mandibular congenital cystic lymphangiomas in the pediatric surgery department of the Donka National Hospital (HND) Conakry. Patients and methods: This is a retrospective and descriptive study of 13 files lasting 7 years from January 2015 to December 31, 2021. The files of children whose age is less than or equal to 15 years operated on cervical tumor with histological evidence of cystic lymphangioma were retained. The data were analyzed using SPSS statistical software 21 and anonymously. Results: The incidence of this study was 1.86 cases per year and a sex ratio of 0.62 in favor of girls. The average age was 8 months 19 days. In the antecedents, we only find poorly monitored pregnancies. The average size of the tumors was 11.85 cm. Cervical ultrasound and standard x-ray of the cervical mass were the only examinations performed. Total surgical excision of the cervical tumor was performed in all patients. The mass was polycystic on exploration. The histological examination of the surgical specimens was in favor of a cystic lymphangioma. The surgical consequences were simple in 11 patients (84.62%) and complicated by parietal suppuration in 2 cases (15.38%). There were no cases of recurrence after one year of follow-up. Conclusion: Cervico-mandibular cystic lymphangiomas are the most frequent locations of congenital lymphangiomas in children. Their severity is linked to the risk of compression of the aero-digestive tracts. Their diagnosis must be confirmed by the histology of the surgical specimen. Despite the therapeutic arsenal, excision of the cystic mass remains the only effective alternative in our socio-economic conditions to avoid recurrences and loss of follow-up of patients.
文摘With the arrival of the 4G and 5G,the telecommunications networks have experienced a large expansion of these networks.That enabled the integration of many services and adequate flow,thus enabling the operators to respond to the growing demand of users.This rapid evolution has given the operators to adapt,their methods to the new technologies that increase.This complexity becomes more important,when these networks include several technologies to access different from the heterogeneous network like in the 4G network.The dimensional new challenges tell the application and the considerable increase in demand for services and the compatibility with existing networks,the management of mobility intercellular of users and it offers a better quality of services.Thus,the proposed solution to meet these new requirements is the sizing of the EPC(Evolved Packet Core)core network to support the 5G access network.For the case of Orange Guinea,this involves setting up an architecture for interconnecting the core networks of Sonfonia and Camayenne.The objectives of our work are of two orders:(1)to propose these solutions and recommendations for the heart network EPC sizing and the deployment to be adopted;(2)supply and architectural interconnection in the heart network EPC and an existing heart network.In our work,the model of traffic in communication that we use to calculate the traffic generated with each technology has link in the network of the heart.
文摘Introduction: The birth of a baby is a moment of joy and celebration. However, the neonatal period is a very delicate phase of life. Neonatal mortality rates remain high in low-income countries. In Guinea, after 20 years, this rate has fallen from 34.2% in 1998 to 32% in 2018. Objective: To identify the main risk factors for neonatal mortality. Methods: This was an observational, analytical case-control study, lasting 6 months from January 1 to June 30, 2019, conducted at the Institut de Nutrition et de la Santé de l’Enfant (INSE) at Donka National Hospital. Results: We collected 242 cases and 242 controls, i.e. a total of 484 records. 748 patients were registered, with 32.35% deaths. 82.86% of deaths occurred in the early neonatal period. Statistical analysis revealed the main risk factors: prematurity (RQ 7.39 95% CI 3.27 - 16.61 p = 0.0000003), hypothermia (RQ 2.29 95% CI 1.51 - 3.46 p = 0.0001), acute fetal distress (RQ 2.13 95% CI 1.33 - 3.43 p = 0.0016), low birth weight (QR 1.91 95% CI 1.12 - 3.24 p = 0.016), home birth (QR 3.26 95% CI 1.25 - 8.46 p = 0.015). Conclusion: Neonatal mortality is a health problem in the INSE neonatology department. To reduce the mortality rate in this referral facility, it is essential to equip it and provide ongoing training for staff.
文摘The purpose of this work is to assess wind potential on the Kanfarandé site (Guinea). The data used for this research covers a period of 6 years (2018 to 2023) and consists of in situ data (Boké meteorological station) and satellite products via NASA Power Larc. The study is based on sorted hourly data (speed and direction). The treatments focus on the monthly, annual and seasonal average of speeds, by sector and their frequencies as well as the annual available powers. The obtained results made it possible, on the one hand, to assess wind potential and, on the other hand, to highlight the most favorable periods for wind energy exploitation. The analyzes show the months of July and August have the best average wind speeds with 5.01 m/s and 5.34 m/s respectively. Average wind speeds are higher during the day than at night with a peak observed at 6 p.m. The study also shows that the prevailing winds are oriented towards the South-West. The Weibull parameters determined for the site give an average of 4.5 m/s for the scale parameter and for the shape parameter 2.40 corresponding to an average power density of 65 w/m2 with an annual available power of 194.80 W/m2 and an annual available energy of 1706.45 kWh/m2.
文摘Leafhoppers (jassids) are well-known pests of vegetable crops in Niger. They are often part of a parasitic complex that causes varying degrees of damage. Over the last two crop years, the Niamey region has seen a heavy outbreak of leaf hoppers on okra and guinea sorrel. These insects alone have caused spectacular damage, resulting in losses ranging from 50% to 100% of unharvested plants. Following this observation, infested fields were surveyed, specimens sampled, and the responsible species identified. Two sites were surveyed in the city of Niamey. At each site, two plots of okra and two of guinea sorrel were visited. Fifty (50) plants were randomly sampled using the double “W” method per plot. The sampled plants were used for active and passive leaf hopper capture, damage description and loss assessment. Captured leaf hoppers were identified based on their morphology observed with a binocular magnifying glass and compared with the data in the identification keys. The symptoms observed in the plots were yellowing, leaf curling and drying, stunting, abortion of flowers and immature fruit and very low production. Identification results revealed the single species Amrasca biguttula (Ishida, 1913), which can be considered a new invasive species in Niger. Further confirmation of this identification by molecular tests, the distribution of the pest in Niger and the development of appropriate control methods would yield good prospects.
文摘This article looks at the developments of computing in Papua New Guinea (PNG) in the post-independence era. More specifically, this article examines the development of national policies on Information and Communications Technology (ICT), digital technologies in PNG, and the development of computing education in PNG since 1975. The research findings reveal that PNG has made solid progress in computing, ICT, national ICT policies, digital technologies, and computing education at universities in the post-independence era. The proposed approach in this article might facilitate the research and development of computing, ICT, digital technologies, and big data analytics in PNG, and beyond.
文摘Each year, rabies kills nearly 60,000 people worldwide. Asia and Africa are the most affected. It is a public health problem because of the number of stray dogs in these nations. In Guinea, rabies is endemic and cases are often under-reported. The objective of this study was to determine the prevalence of rabies among human and animal exposures in Guinea. This was a retrospective analytical study from 2019 to 2021 conducted in the country’s human and veterinary health divisions and, primarily focused on rabies épidémiologique surveillance. The selection was based on human contact with an animal causing behavioural disorders, as well as animals put under observation following aggression on humans. The data were analysed using Epi Info version 21 software. Qualitative variables were expressed as proportions with 95% CIs, quantitative variables as mean ± standard deviation. The chi2 test and the Fischer exact test were used to compare proportions. A total of 85 veterinary facilities were visited and 100 animals registered, of which 93% were reported cases of exposure to canine rabies. One thousand five hundred and thirty-one (1531) people exposed to rabies were recorded between 2019 and 2021. During the period, the prevalence of human rabies was 0.533% [0.042 - 0.064] at 95% CI and that of canine rabies was 0.55% [0.039 - 0.061] at 95% CI. The biting animal was the dog in 97.2% of cases. Subjects over 45 years of age (57.7%) were the most affected. The prevalence of canine rabies was 0.5% compared with 0.533% for human rabies between 2019 and 2021. This low prevalence does not reflect the true extent of the phenomenon in Guinea, as few people consult health structures in the event of dog bites. Regular surveillance of the human and dog population is necessary for better rabies control in Guinea.
文摘The chemical and mineralogical composition of bauxite deposits is a key factor in the profitability of refining processes. The study of bauxites from the Saföfö site has assessed variations in chemical and mineralogical composition under various conditions, as well as the optimum conditions for their exploitation. The methodologies used in this study include experimental methods for determining moisture content, chemical composition, mineralogical composition, and specific density of bauxite. The results show significant variation in moisture content among the bauxite samples, with values ranging from 2.90% to 17.80%. The silica percentages in the samples range from 1.69% to 8.14%, while alumina percentages vary from 36.81% to 54.03%. After calcination, alumina oxide percentages range from 40% to 75%. After chemical activation, alumina oxides Al2O3 range from 40% to over 50%. Gibbsite is the most abundant mineral, accounting for about 60% - 70% of the total composition of the bauxite samples. Samples A to F have bulk densities varying between approximately 3.6 and 3.9. Sample B has the highest density, around 3.9, while sample C has the lowest, at around 3.5. Bauxite mining at the Saföfö site offers significant potential for the alumina industry, provided appropriate processing methods are selected to maximize quality and profitability while minimizing environmental impact.
基金Supported by National Key R&D Program of China(No.2021YFC2702103,No.2021YFC2702100)the National Natural Science Foundation of China(No.82104937)the Key R&D Program of Shandong Province(No.2019GSF108252).
文摘AIM:To investigate the effect of electroacupuncture(EA)on the mitochondria-dependent apoptotic signaling pathway in the ciliary muscle of guinea pigs with negative lensinduced myopia(LIM).METHODS:Guinea pigs were randomly divided into normal control(NC)group,LIM group,LIM+SHAM acupoint(LIM+SHAM)group,and LIM+EA group.Animals in the NC group received no intervention,while those in other three groups were covered with-6.0 diopter(D)lenses on right eyes.Meanwhile,animals in the LIM+EA group received EA at Hegu(LI4)combined with Taiyang(EX-HN5)acupoints,while those in the LIM+SHAM group were treated at sham points.After treatments for 1,2,and 4wk,morphological changes in ciliary muscles were observed with hematoxylin and eosin(H&E)staining and nick end labeling(TUNEL),and the expression of the mitochondrial apoptotic signaling pathway-related molecules in ciliary muscles was measured by real-time quantitative polymerase chain reaction(qPCR)and Western blot.Additionally,the adenosine triphosphate(ATP)contents were also determined in ciliary muscles.RESULTS:Axial length increased significantly in the LIM and LIM+SHAM groups and decreased in the LIM+EA group.The ciliary muscle fibers were broken and destroyed in both LIM and LIM+SHAM groups,whereas those in the LIM+EA group improved significantly.TUNEL assay showed the number of apoptotic cells increased in the LIM and LIM+SHAM groups,whereas reduced in the LIM+EA group.ATP contents showed a significant decrease in the LIM and LIM+SHAM groups,whereas increased after EA treatment.Compared with the NC group,the dynamin-related protein 1(DRP1),Caspase3,and apoptotic protease activator 1(APAF1)levels were significantly increased in the LIM group and decreased in the LIM+EA group.CONCLUSION:The results provide evidence of EA inhibiting the development of myopia by regulating the mitochondrial apoptotic signaling pathway.
基金funded by the National Natural Science Foundation of China (Grant No. 51920105013)。
文摘Waves play a major role in the ocean phenomena in the Gulf of Guinea(GoG). In order to reveal the spatial-temporal distribution characteristics and the propagation mechanism of waves from the South Atlantic Ocean to the GoG, 4typical points located in mid-latitude of South Atlantic(14°30′W, 30°0′S), south of the GoG(10°30′W, 15°0′S), offshore of the GoG(0°0′, 0°0′) and near shore of the GoG(6°4′58.8″W, 4°3′36″S) are selected, and waves from Atlantic Ocean to GoG are simulated by using a two-layer-nesting wave numerical model SWAN(Simulating Waves Nearshore). The results show that the hybrid waves(waves hereafter) and the swells have strong relationship with local wind in Roaring Forties and at mid-latitude of South Atlantic Ocean, while there is no obvious correlation between waves and local winds in the GoG. Swells are generated in the South Atlantic Ocean and propagate into the GoG. 2D wave spectra at the four selected typical points are simulated. The spectral pattern and wave component structure indicate that the wave system in GoG is dominated by the S-SW swells generated from Roaring Forties and mid-latitude of South Atlantic, whether it is at maximum(2.2-2.8 m), medium(1.8-2.2 m) or minimum(1.2 m) significant wave height in the GoG during simulation period.
文摘Ebstein’s anomaly is a rare congenital heart disease. We report a series of 4 cases of Ebstein’s anomaly discovered in adolescents. The mean age was 13.75 ± 0.96, with 3 boys and one girl. Three were in heart failure. The EKG showed atrial hypertrophy (1 case), right bundle branch block (1 case), Wolff-Parkinson-White (1 case), and atrial fibrillation (1 case). Cardiomegaly was present in all patients with a mean cardiothoracic index of 0.77 ± 0.03. On echocardiography, the mean apical displacement of the tricuspid septal leaflet was 22.5 ± 3.30 mm/m<sup>2</sup>, the Celermajer index was Grade 2 in 2 patients and Grade 4 in 2 patients. Depletive medical treatment was prescribed to 3 patients. Anticoagulant therapy was initiated in one patient. Two are awaiting surgery. One death was recorded, it was at Grade 4 of the Celermajer index.
文摘The impacts of climate change on crop yields are receiving renewed interest,with focus on cereals and staple crops at the regional and national scales.Yet,the impacts of climate change on the yields of leguminous crops in the local context has not been explored.Thus,an in-depth understanding of climate change in the local context may support the design of locally relevant adaptation responses to current and future climate risks.This study examined the impacts of climate variables(annual rainfall,annual average temperature,rainfall indices(rainfall onset,rainfall cessation,and the length of rainy days),and the number of dry days)on the yields of leguminous crops(groundnuts,cowpeas,and soybeans)in the Guinea Savanna agroecological zone of Ghana during the period of 1989-2020.The data were analysed using Mann-Kendall’s trend,Sen’s slope test,correlation analysis,and Multiple Regression Analysis(MRA).The findings revealed that annual rainfall,annual average temperature,rainfall onset,rainfall cessation,and the length of rainy days,and the number of dry days all showed varied impacts on the yields of groundnuts,cowpeas,and soybeans.The trend analysis detected a marginal decrease in the amount of rainfall,rainfall onset,and the number of dry days from 1989 to 2020(P>0.050).Annual average temperature and the length of rainy days substantially varied(P<0.050)from 1989 to 2020,showing an increasing trend.The findings also showed a marked upward trend for the yields of groundnuts,cowpeas,and soybeans during 2005-2020.The climate variables analysed above increased the yields of groundnuts,cowpeas,and soybeans by 49.0%,55.0%,and 69.0%,respectively.The yields of groundnuts,cowpeas,and soybeans fluctuated with the variability of 30.0%,28.0%,and 27.0%from 2005 to 2020,respectively.The three leguminous crops under study demonstrated unpredictable yields due to the variations of annual rainfall,annual average temperature,rainfall onset,rainfall cessation,the length of rainy days,and the number of dry days,which stressed the need for agricultural diversification,changing planting dates,using improved seed variety,and irrigation to respond to climate change.The results of this study implied that climate change considerably impacts crop production in the Guinea Savanna agroecological zone of Ghana,emphasizing the urgency of locally based and farmer-induced adaptation measures for food security and resilient agricultural systems.
文摘Introduction: Unmet need for family planning (UNFP) is defined as women with unmet needs who want to stop or delay childbearing but are not using any method of contraception. The objective of this study was to analyze the factors associated with unmet needs for family planning among couples living in rural and urban areas of Guinea in 2019. Methodology: This was a prospective, analytical cross-sectional, multicenter study of a six-month period from August 1, 2018 to January 31, 2019, focusing on couples with unmet needs for family planning. Result: Among 189 couples interviewed, 567 had UNFP (33.3%), the reasons for not using modern contraceptive methods were desire for pregnancy (AOR = 2.74, 95% CI: 1.74, 4.31), husband’s refusal (AOR = 0.23, 95% CI: 0.06, 0.81), spousal attitude (AOR = 0.20, 95% CI: 0.130, 30), birth spacing (AOR = 2.10% to 95%: 1.16, 3.82), difficulty with a new pregnancy (AOR = 0.17, 95% CI: 0.04, 0.74), and spousal attitude (AOR = 0.20, 95% CI: 0.14, 0.30). Conclusion: The involvement of spouses, especially in rural communities, would help achieve family planning objectives and reduce unmet needs for family planning.