Acanthosis nigricans is characterized by papillomatous brownish lesions mainly in the intertriginous areas. We used dermoscopy to examine such lesions in a family with acanthosis nigricans. The dermoscopic images show...Acanthosis nigricans is characterized by papillomatous brownish lesions mainly in the intertriginous areas. We used dermoscopy to examine such lesions in a family with acanthosis nigricans. The dermoscopic images showed an aberrant skin structure of linear crista cutis and sulcus cutis, and hyperpigmented dots in crista cutis. The hyperpigmented dots, which could not be seen with the naked eyes, may contribute to the color of the pigmented skin. Dermoscopy can be useful for evaluating disorders involving the structure of area cutanea and a change in skin color.展开更多
Background: Wrinkles, pigmented spots, and roughness are representative parameters reflecting facial skin aging. Sulci cutis connecting to follicular orifices frequently form perifollicular cracks, which join together...Background: Wrinkles, pigmented spots, and roughness are representative parameters reflecting facial skin aging. Sulci cutis connecting to follicular orifices frequently form perifollicular cracks, which join together adjacent sulci. This follicle-sulcus-crack complex (FSCC) is exacerbated by dehydration. Purpose: Although dehydration is associated with facial skin aging, FSCC’s implications in facial skin aging remain unresolved. Method: We measured facial skin parameters in 1999 and 2010 in 108 Japanese women, and in 2006 and 2016 in 182 Chinese women. We addressed whether expansion of FSCC is associated with other skin aging parameters. We also examined whether skin moisturizer can reverse the expanded FSCC. Results: In both clinical studies, FSCC severity as well as wrinkles, spots, and roughness significantly deteriorated with age. Notably, FSCC significantly increased as early as in subjects in their 20s, whereas wrinkles, spots, and roughness became conspicuous in those in their 40s or older. Moreover, subjects with more severe FSCC in the initial measurement exhibited significantly worse wrinkles, spots, and roughness in the second measurement a decade later. Dehydration was significantly correlated with expanded FSCC. Furthermore, FSCC expansion was reversed after appropriate moisturization by daily application of Galactomyces ferment filtrate (GFF)-containing skincare product (SK-II Skin Power Cream) for 4 weeks in 37 women. Conclusion: The expanded FSCC is likely to be an early indicator of facial skin aging. Appropriate moisturization may reduce FSCC formation and decelerate facial skin aging.展开更多
Objective:Pityriasis versicolor(PV)is usually a clinical diagnosis.In uncertain cases,PV is confirmed by microscopic examination with 10%potassium hydroxide(KOH).However,the KOH test is not 100%sensitive in diagnosing...Objective:Pityriasis versicolor(PV)is usually a clinical diagnosis.In uncertain cases,PV is confirmed by microscopic examination with 10%potassium hydroxide(KOH).However,the KOH test is not 100%sensitive in diagnosing PV.Dermoscopy of PV is still an unexplored area with very little data reported.This study was planned to study the various dermoscopic features and their utility in the diagnosis of PV.Methods:This cross-sectional observational study was carried out over a 1-year period(September 2020-September 2021)among 57 patients with KOH-confirmed PV.All patients underwent dermoscopy using a handheld dermoscope(DermLite DL4;DermLite LLC).The chi-square test or Fisher’s exact test was used to analyze the data.Results:Of the 57 patients,43(75.44%)had the hypopigmented type,followed by the hyperpigmented type(n=12,21.05%)and the perifollicular type(n=2,3.51%).Nonuniform pigmentation was the most common dermoscopic finding observed in both patients with hypopigmented PV(n=42,97.67%)and hyperpigmented PV(n=12,100%)(P=0.001).Scaling was the second most commonly observed finding;patchy scaling(n=25,58.13%)and perifollicular scaling(n=13,30.23%)were commonly seen in hypopigmented PV,while hyperpigmented PV showed more diffuse scaling(n=6,50.00%)(P=0.04)followed by patchy scaling(n=5,41.66%).Dermoscopy showed unique“double-edged scales”in all lesions with furrow scaling(n=11,19.30%)after eliciting a positive evoked scale sign.Other interesting features seen in hypopigmented PV were hypopigmentation around the hair follicle(n=24,55.48%)(P=0.001)and perilesional hyperpigmentation(the halo sign)(n=15,34.88%)(P=0.04).Conclusion:We observed several dermoscopic findings in PV that can serve as useful clues for differentiating PV from other similar disorders.展开更多
文摘Acanthosis nigricans is characterized by papillomatous brownish lesions mainly in the intertriginous areas. We used dermoscopy to examine such lesions in a family with acanthosis nigricans. The dermoscopic images showed an aberrant skin structure of linear crista cutis and sulcus cutis, and hyperpigmented dots in crista cutis. The hyperpigmented dots, which could not be seen with the naked eyes, may contribute to the color of the pigmented skin. Dermoscopy can be useful for evaluating disorders involving the structure of area cutanea and a change in skin color.
文摘Background: Wrinkles, pigmented spots, and roughness are representative parameters reflecting facial skin aging. Sulci cutis connecting to follicular orifices frequently form perifollicular cracks, which join together adjacent sulci. This follicle-sulcus-crack complex (FSCC) is exacerbated by dehydration. Purpose: Although dehydration is associated with facial skin aging, FSCC’s implications in facial skin aging remain unresolved. Method: We measured facial skin parameters in 1999 and 2010 in 108 Japanese women, and in 2006 and 2016 in 182 Chinese women. We addressed whether expansion of FSCC is associated with other skin aging parameters. We also examined whether skin moisturizer can reverse the expanded FSCC. Results: In both clinical studies, FSCC severity as well as wrinkles, spots, and roughness significantly deteriorated with age. Notably, FSCC significantly increased as early as in subjects in their 20s, whereas wrinkles, spots, and roughness became conspicuous in those in their 40s or older. Moreover, subjects with more severe FSCC in the initial measurement exhibited significantly worse wrinkles, spots, and roughness in the second measurement a decade later. Dehydration was significantly correlated with expanded FSCC. Furthermore, FSCC expansion was reversed after appropriate moisturization by daily application of Galactomyces ferment filtrate (GFF)-containing skincare product (SK-II Skin Power Cream) for 4 weeks in 37 women. Conclusion: The expanded FSCC is likely to be an early indicator of facial skin aging. Appropriate moisturization may reduce FSCC formation and decelerate facial skin aging.
文摘Objective:Pityriasis versicolor(PV)is usually a clinical diagnosis.In uncertain cases,PV is confirmed by microscopic examination with 10%potassium hydroxide(KOH).However,the KOH test is not 100%sensitive in diagnosing PV.Dermoscopy of PV is still an unexplored area with very little data reported.This study was planned to study the various dermoscopic features and their utility in the diagnosis of PV.Methods:This cross-sectional observational study was carried out over a 1-year period(September 2020-September 2021)among 57 patients with KOH-confirmed PV.All patients underwent dermoscopy using a handheld dermoscope(DermLite DL4;DermLite LLC).The chi-square test or Fisher’s exact test was used to analyze the data.Results:Of the 57 patients,43(75.44%)had the hypopigmented type,followed by the hyperpigmented type(n=12,21.05%)and the perifollicular type(n=2,3.51%).Nonuniform pigmentation was the most common dermoscopic finding observed in both patients with hypopigmented PV(n=42,97.67%)and hyperpigmented PV(n=12,100%)(P=0.001).Scaling was the second most commonly observed finding;patchy scaling(n=25,58.13%)and perifollicular scaling(n=13,30.23%)were commonly seen in hypopigmented PV,while hyperpigmented PV showed more diffuse scaling(n=6,50.00%)(P=0.04)followed by patchy scaling(n=5,41.66%).Dermoscopy showed unique“double-edged scales”in all lesions with furrow scaling(n=11,19.30%)after eliciting a positive evoked scale sign.Other interesting features seen in hypopigmented PV were hypopigmentation around the hair follicle(n=24,55.48%)(P=0.001)and perilesional hyperpigmentation(the halo sign)(n=15,34.88%)(P=0.04).Conclusion:We observed several dermoscopic findings in PV that can serve as useful clues for differentiating PV from other similar disorders.
