A 63-year-old man with diabetes and asymptomatic coronary artery disease developed refractory ventricular arrhythmia at 20 hours at rest after his second COVID-19 vaccine. Despite significant stenosis in the coronary ...A 63-year-old man with diabetes and asymptomatic coronary artery disease developed refractory ventricular arrhythmia at 20 hours at rest after his second COVID-19 vaccine. Despite significant stenosis in the coronary arteries, there was no evidence of acute or old myocardial infarction, heart failure, myocarditis or structural abnormalities on post-mortem to account for the substrate for the fatal arrhythmia. The refractory and incessant nature of the ventricular fibrillation and post-mortem finding of a grossly elevated unexplained IgE level (in the absence of acute myocardial infarction) suggested the possibility of Kounis Syndrome or allergic acute coronary syndrome.展开更多
1病例资料
患者,女,52岁,黄种人,农民,既往有原发性高血压（高血压）病史7~8年,血压最高190/110 mm Hg（1 mm Hg=0.133 k Pa）,有高血压家族史。患者于2015年3月14日22：00于家中进食后出现剑突下不适,恶心并呕吐1次,呕吐物为胃内容物...1病例资料
患者,女,52岁,黄种人,农民,既往有原发性高血压（高血压）病史7~8年,血压最高190/110 mm Hg（1 mm Hg=0.133 k Pa）,有高血压家族史。患者于2015年3月14日22：00于家中进食后出现剑突下不适,恶心并呕吐1次,呕吐物为胃内容物,自述伴有舌体肿胀,全身皮肤瘙痒,大汗,急呼120救护车。展开更多
1 Introduction Kounis syndrome constitutes a coronary hypersensitivity disorder defined by the association of an anaphylactoid,anaphylactic,allergic or hypersensitivity reaction with an acute coronary syndrome,in a ph...1 Introduction Kounis syndrome constitutes a coronary hypersensitivity disorder defined by the association of an anaphylactoid,anaphylactic,allergic or hypersensitivity reaction with an acute coronary syndrome,in a physiopathological context involving various interrelated and interacting inflammatory cells,such as mast-cells,eosinophils and platelets.[1,2]Similar entities to Kounis syndrome might involve cerebral and mesenteric arteries.展开更多
文摘A 63-year-old man with diabetes and asymptomatic coronary artery disease developed refractory ventricular arrhythmia at 20 hours at rest after his second COVID-19 vaccine. Despite significant stenosis in the coronary arteries, there was no evidence of acute or old myocardial infarction, heart failure, myocarditis or structural abnormalities on post-mortem to account for the substrate for the fatal arrhythmia. The refractory and incessant nature of the ventricular fibrillation and post-mortem finding of a grossly elevated unexplained IgE level (in the absence of acute myocardial infarction) suggested the possibility of Kounis Syndrome or allergic acute coronary syndrome.
文摘1病例资料
患者,女,52岁,黄种人,农民,既往有原发性高血压（高血压）病史7~8年,血压最高190/110 mm Hg（1 mm Hg=0.133 k Pa）,有高血压家族史。患者于2015年3月14日22：00于家中进食后出现剑突下不适,恶心并呕吐1次,呕吐物为胃内容物,自述伴有舌体肿胀,全身皮肤瘙痒,大汗,急呼120救护车。
文摘1 Introduction Kounis syndrome constitutes a coronary hypersensitivity disorder defined by the association of an anaphylactoid,anaphylactic,allergic or hypersensitivity reaction with an acute coronary syndrome,in a physiopathological context involving various interrelated and interacting inflammatory cells,such as mast-cells,eosinophils and platelets.[1,2]Similar entities to Kounis syndrome might involve cerebral and mesenteric arteries.
