载脂蛋白E敲除(ApoE^(-/-))小鼠整装(whole-mount)主动脉免疫荧光组织化学染色的血管外膜淋巴管成像

目的 探索载脂蛋白E敲除(ApoE^(-/-))小鼠整装(whole-mount)主动脉免疫荧光组织化学染色法显示血管外膜淋巴管的可行性。方法 制备ApoE^(-/-)小鼠整装主动脉,进行淋巴管内皮受体1(LYVE1)、 α平滑肌肌动蛋白(α-SMA)免疫荧光组织化学染色,染色后组织经5 g/L苏丹黑B处理30 min、组织透明液透明,移至自制的样本容器中,荧光显微镜下成像。结果经5 g/L苏丹黑B处理的整装主动脉可见血管自发荧光显著降低,外膜淋巴管的特异性荧光强度显著增强,更易观察且不会对其他通道荧光产生干扰。结论 建立的ApoE^(-/-)小鼠整装主动脉免疫荧光组织化学染色显示血管外膜淋巴管的方法操作简便,特异性好。

Volcanic Risk Perception and Coping Strategies from Mounts Cameroon and Nyiragongo Eruptions, Central Africa: A Comparative Analysis

Approximately 2,000,000 people are exposed to volcanic risks in communities situated at the flanks of Mounts Cameroon (MC) and Nyiragongo (MN) volcanoes in Central Africa. This study therefore sought to investigate risk perception from four previous eruptions of MC, namely the 1959, 1982, 1999, and 2000 eruptions;and two previous eruptions of MN: 1977 and 2002. The study was initiated with co-design workshops held with major stakeholders in the cities of Buea and Goma at the flanks of MC and MN, respectively, in 2017, to develop the research objectives for the study. A non-random questionnaire survey was later conducted within 14 and 15 communities in Buea and Goma respectively, on the effects, perceived risks, and coping strategies for the chosen eruptions. Three age groups (18 - 30, 31 - 45 and >45 years) and gender (male and female) were considered. The population at the flanks of both volcanoes cited scientific and indigenous factors to be responsible for eruptions from these volcanoes. At MC and MN, ≥45% of the sampled participants (with a higher female population) perceived that the sampled eruptions posed a very high risk to the population. In terms of the effects, the age group of 18 - 30 was the least knowledgeable. In terms of direct effect on persons, over 90% of participants at MC and MN attested that they were overcome by fear/panic. On measures to cope with any likely eruption, the following order was established at the flanks of both volcanoes: sensitization of population, use of religious (prayers) and of traditional/indigenous strategies. In terms of future coping strategies, while the males at MC maintained sensitization as the favourite option, 62% of the males at MN opted for traditional/indigenous strategies. The female population at both MC and MN showed a higher preference for religious strategies like prayers.

Variation in the surface heat flux on the north and south slopes of Mount Qomolangma

The distinctive conditions present on the north and south slopes of Mount Qomolangma,along with the intricate variations in the underlying surfaces,result in notable variations in the surface energy flux patterns of the two slopes.In this paper,data from TESEBS(Topographical Enhanced Surface Energy Balance System),remote sensing data from eight cloud-free scenarios,and observational data from nine stations are utilized to examine the fluctuations in the surface heat flux on both slopes.The inclusion of MCD43A3 satellite data enhances the surface albedo,contributing to more accurate simulation outcomes.The model results are validated using observational data.The RMSEs of the net radiation,ground heat,sensible heat,and latent heat flux are 40.73,17.09,33.26,and 30.91 W m^(−2),respectively.The net radiation flux is greater on the south slope and exhibits a rapid decline from summer to autumn.Due to the influence of the monsoon,on the north slope,the maximum sensible heat flux occurs in the pre-monsoon period in summer and the maximum latent heat flux occurs during the monsoon.The south slope experiences the highest latent heat flux in summer.The dominant flux on the north slope is sensible heat,while it is latent heat on the south slope.The seasonal variations in the ground heat flux are more pronounced on the south slope than on the north slope.Except in summer,the ground heat flux on the north slope surpasses that on the south slope.

Evaluation of periglacial landforms and formation of soil properties on the Mount Honaz,SW Türkiye

The main aim of this study is to explain periglacial processes on the summits of Mount Honaz(2571 m a.s.l.),define periglacial landforms,and determine the relationships between morphometric features and topographic factors.Mud circles,stony earth circles,non sorted steps,and non sorted stripes were identified on the summits of Mount Honaz.Pearson's correlation coefficient(r)and linear regression analyses were performed by taking metric measurements from 125 periglacial landforms to describe their morphometric features(length,width,height)of periglacial landforms and explain the relationships between them and topographic factors(elevation,slope).To explain the relationships between periglacial landforms and soil properties,soil samples from 11 periglacial landforms were taken and analysed.Periglacial landforms,which continue to develop on the summits of Mount Honaz today,have been evaluated with present climate data.Analysis of soil samples indicates a notable impact of parent material on the genesis of periglacial landforms.The high ratio of organic matter in mud circle and non sorted step landforms and the high lime ratio in stony earth circle landforms prove a strong relationship between the formation mechanisms of landforms and the soil properties.Furthermore,it is consistent with the findings obtained from the analysis that severe periglacial processes and washing and scavenging events are experienced more on the northern slopes.

The Applicability and Productiveness of a Systematic Literature Review Methodology in Volcanology Research: Case of the Magma Pathway at the Mount Cameroon Volcano

The presented research illustrates the applicability and productiveness of the systematic literature review methodology, a non-empirical methodology in the geological sciences, particularly volcanology. The systematic literature review methodology is a replicable, rigorous, and transparent methodology for synthesizing existing literature to answer questions on a specific topic. The synthesis allows for knowledge consolidation, such as identifying knowledge gaps. In our illustration of this methodology, we focused on the expanding knowledge about the magma pathway at Mount Cameroon, one of Africa’s active volcanoes. Our synthesis of the relevant international geoscience research literature is based on the framework of knowledge about the magma pathway beneath a typical basaltic volcano. The framework has three primary components: magma supply, storage, and transport to erupting vents. Across these components is a total of twelve secondary components. The result is a previously non-existent and fragmented overall understanding of the magma pathway at Mount Cameroon. The gaps in the understanding (such as in the magma supply rates, timescales of chamber processes, and magma ascent rates) may be addressed in future research. Another key implication of the presented research lies in the proof of concept of the systematic literature review methodology as an applicable qualitative research methodology in the study of volcanoes.

GO WEST TO THE HOMETOWN OF MOUNT QOMOLANGMA

Lakes that resemble mirrors and jade,ancient temples,and Mount Qomolangma soaring into the clouds...If you want to experience the unique folk culture of Xizang,you can head west to Xigaze,the hometown of Mount Qomolangma.

Study on Over-urbanization of the Ecotone between Mount Tai and Tai'an City

By investigating the ecotone between Mount Tai Scenic Area and downtown area of Tai'an City,the characteristics of such an ecotone are analyzed,serious problems brought by the over-urbanization to local natural environment,such as destruction of eco-environment,aggravated pollution and degradation of mountainous landscape resources are studied.Then countermeasures for the harmonious development of the ecotone are proposed to better promote the coordinated development of cities and mountainous scenic areas.

C-mount封装不同激光器芯片尺寸的热阻分析

采用波长漂移法对基于C-mount封装类型的不同尺寸芯片的热阻进行测量,得到了使热阻最小的最佳芯片尺寸和铟焊料厚度。测量结果表明,在铟焊料厚度为10μm、输出功率为2 W、条宽为200μm、腔长为2 000μm时,激光器芯片的热阻最小值为2.01℃/W。在铟焊料厚度为5μm和10μm两种条件下,对腔长为2 000μm的不同条宽的激光器芯片的热阻进行了测量,在铟焊料厚度为5μm时,激光器芯片的热阻由原来的2.01℃/W降到了1.85℃/W。

Linking uplift and mineralisation at the Mount Novit Zn-Pb-Ag Deposit,Northern Australia:Evidence from geology,U-Pb geochronology and sphalerite geochemistry

The subeconomic Mount Novit Zn-Pb-Ag deposit is located approximately 20 km south of Mount Isa,Queensland.In contrast to the nearby Mount Isa,Hilton and George Fisher Zn-Pb-Ag deposits,mineralisation at Mount Novit is situated to the west of the regional-scale Mount Isa Fault and is hosted in the Moondarra Siltstone as opposed to the Urquhart Shale.Lower-grade(<4 wt.%Zn+Pb)Zn-Pb-Ag mineralisation primarily replaces pre-existing carbonate alteration and veining and consists of pyrrhotite,pyrite and sphalerite with lesser galena.Higher-grade(>10 wt.%Zn+Pb)mineralisation occurs as a matrix supported breccia dominated by sphalerite and pyrrhotite with galena,pyrite,and magnetite.In-situ U-Pb geochronology was completed on apatite and two textural varieties of monazite.Fine-grained(<50μm)subhedral to anhedral monazite is located within highly foliated biotite alteration directly adjacent Zn-Pb-Ag mineralisation and yields a mean weighted^(207)Pb/^(206)Pb age of 1527±18 Ma(MSWD=1.06).This age is consistent with the formation of highly foliated biotite alteration during D;deformation of the Isan Orogeny.Apatite from the same fabric yields a lower intercept age of1443±29 Ma(MSWD=1.30).Consistent with previous studies,this age is interpreted to represent the age of a major thrusting event along the Mount Isa Fault that resulted in the cooling of the Mount Novit area below~375℃.Coarse-grained monazite is coeval with Zn-Pb-Ag mineralisation and yields a mean weighted^(207)Pb/^(206)Pb age of 1457±11 Ma(MSWD=0.28).Sphalerite from Mount Novit has low concentrations(<1 ppm)of Ge and Ga and a relatively high concentration of In(5 to>10 ppm),possibly reflecting the leaching of the metals from an underlying basement unit.The GGIMFis geothermometer(Frenzel et al.,2016)produced a mean formation temperature of 345±52℃.The timing and temperature of Zn-Pb-Ag mineralisation is consistent with the age and cooling temperature of apatite presented in this study.Based on these correlations,we suggest that Zn-Pb-Ag mineralisation at Mount Novit was emplaced during an episode of major thrusting along the Mount Isa Fault,with the precipitation of Zn-Pb-Ag mineralisation driven by the cooling of the Mount Novit area below~375℃.A key implication of this study is a new model for synorogenic Zn-Pb-Ag mineralisation to the south of Mount Isa,which contrasts with the widely accepted regional-scale syngenetic metallogenic model.

Ride quality evaluation of the soil compactor cab supplemented by auxiliary hydraulic mounts via simulation and experiment

In order to evaluate the ride quality of the soil compactor cab supplemented by the auxiliary hydraulic mounts (AHM), a nonlinear dynamic model of the soil compactor interacting with the off-road deformable terrain is established based on Matlab/Simulink sofware. The power spectral density (PSD) and the weighted root mean square (RMS) of acceleration responses of the vertical driver s seat, the cab s pitch and roll angle are chosen as objective functions in low-frequency range. Experimental investigation is also used to verify the accuracy of the model. The influence of the damping coefficients of the AHM on the cab s ride quality is analyzed, and damping coefficients are then optimized via a genetic algorithm program. The research results show that the cab s rubber mounts added by the AHM clearly improve the ride quality under various operating conditions. Particularly, with the optimal damping coefficients of the front-end mounts c a 1,2 = 1 500 N · s/m and of the rear-end mounts c a 3,4 =2 335 N · s/m, the weighted RMS values of the driver s seat, the cab s pitch and roll angle are reduced by 22.2%, 18.8%, 58.7%, respectively. Under the condition of the vehicle travelling, with the optimal damping coefficients of c a 1,2 = 1 500 N · s/m and c a 3,4 =1 882 N · s/m, the maximum PSD values of the driver s seat, the cab s pitch and roll angle are clearly decreased by 36.7%, 54.7% and 50.6% under the condition of the vehicle working.

The ideal landscape and its ecological planning approach in Mount Lushan National Park,China

This paper described the main four basic models of ideal landscape in the Mount Lushan National Park as Kunlunshan model, Xumishan model, Peach flower land model, Christian model. Five typical places in Mount Lushan with the ideal landscape characteristics like the East Grove Temple, White Deer Cave Academy, Simplicity and Tranquility Monastery, Lushan Valley, and Villa-cluster of the East Valley were analyzed, and the integration of the basic models for each place was discussed to make the realistic landscape conform to the ideal needs. Moreover, the discussions also involved the characteristics of ideal landscape that are featured in resource, culture, structure, function, process, scale and region. In conclusion, ideal landscape in the Mount Lushan National Park was the product of the interaction between human and nature. Mount Lushan inherits the essence of Chinese traditional culture with a history of more than 1000 years; and it also absorbs the manna of the Western culture as well as the exchanges between nature and humanities together with the conflict and adaptation among different cultures. The natural landscape could be satisfied with the survival demand and cultural taste of mankind by the way of ecological planning.

Passive Magnetorheological Fluid Filled Hydraulic Engine Mount

Using magnetorheological (MR) fluids in hydraulic engine mount for damping vehicle noise and vibration is opposed firstly, the structure of passive type and its mechanical model are described. The analysis of the experimental data show that the dynamic characteristics of MR mount such as dynamic stiffness and loss angles vary distinctly as the excitation frequency, and MR fluids as one type of attracting controllable fluids are fit for hydraulic engine mounts. The author advises to work out potentialities of MR fluids, the semi control or active control MR fluids filled hydraulic engine mount must be developed.

Planning and Countermeasures for the Safeguarding of World Heritage in Mount Longhu,Jiangxi Province of China

Aesthetic value,scientific research value and ecological protection value of world heritage in Mount Longhu,Jiangxi Province was analyzed.And the urgency of protecting Danxia landform was clarified from the perspective of influence brought by tourism development,population explosion,economic development and natural disasters.Planning and management agencies and relevant policy support for the safeguarding of world heritage in Mount Longhu,Jiangxi Province were expounded,as well as protective strategies for different zones and grades according to their scientific research value and protection value.Training for the protection and management of Mount Longhu,and local residents' participation in the training were introduced.Finally,suggestions for the heritage protection in Mount Longhu were given:project construction and management should be stressed,operation activities standardized,ticket management for the Longhu World Heritage improved,and the sustainable development persisted in.

澳大利亚北部Mount Isa型铅-锌-银矿成矿模型

澳大利亚的Pb-Zn-Ag矿床主要有4种成矿类型:(1)Mount Isa型,它含有澳大利亚56%的锌,(2)Broken Hill型,它含有澳大利亚19%的锌,(3)火山控制的硫化物矿床型,它含有澳大利亚12%的锌,(4)密西西比河谷型,它占有澳大利亚8%的锌。在澳大利亚北部则主要以Mount Isa型、Broken Hill型和密西西比河谷型为主。Mount Isa型是其中最重要的一类。

STUDY ON VIBRATION REDUCTION BEHAVIOR FOR THE HYDRAULIC ENGINE MOUNT

In this paper,the metal hydraulic engine mount (HEM) with the orifice is presented,the construction of HEM is consist of hydraulic cylinder and the spring on the bottom,its mechanical model is given and dynamics equations are set up with considering kinematics conditions and continuous of fluid,the dynamics behavior of HEM including dynamic stiffness of fluid and transferability of HEM are studied here.The example of hydraulic engine mount is calculated,it is shown that the vibration reduction performance of the hydraulic engine mount of this paper is better.The analysis method of vibration reduction behavior for HEM in this paper can be used in designing of the reduction vibration devices and the HEM in this paper can be used in the practical engineering for reduction vibration.

Variations of extreme temperature in the Mount Qomolangma region in China during 1971-2020

According to observational daily temperature data from the meteorological stations during 1971-2020,the variations of the extreme temperature event in the Mount Qomolangma(also known as Mount Everest) region in China have been analyzed using statistical methods.The extreme temperature indices recommended by the World Meteorological Organization are selected to describe the extreme temperature event.The RClimDEX 1.0 software is used to calculate the extreme temperature indices.There are no tropical nights,and just three summer days at the last 50 years.The frost days are the main extreme temperature events all year round.The temperature in the north slope is more extreme than that in the south slope of the Mount Qomolangma.There is remarkable decadal variation for the extreme temperature indices except diurnal temperature range.There are the warm extremes increasing,however,the cold extremes decreasing with the decadal lapse,which is more remarkable into the 21^(th) century.The tendencies for the extreme temperature indices in the north slope are consistent with those in the south slope.There are statistically significant trends for most extreme temperature indices during the study period.It shows that the warm extremes would be more prominent in the future with the global continued warming.The abrupt changes of the extreme temperature index have occurred mainly in the 20^(th) century especially from the mid to late 1980s and 1990s.The periodic changes in the south slope do not synchronize those in the north slope for the most extreme temperature indices.It is different for most extreme temperature indices between the south and north slope,which has demonstrated that the regional or local changes are not neglectable for extreme temperature research.The results of this study are also the consistent response of extreme temperature event to the global warming.

Effectiveness of Informatization Teaching Design:A Cause Study on Mountain Tourism Resources

With the rapid development of network technology,education informatization has become an inevitable trend in education reform and development.An important aspect of information teaching is the effective integration of information technology and course teaching.On the basis of fully understanding and considering the learning needs of students,we should clarify the teaching goals of mountain tourism resources,integrate relevant teaching content,select appropriate information teaching strategies and methods,and achieve the optimization of teaching effects,so that students can really effectively play the role of the main body in teaching.In the teaching process of mountain tourism resources,the use of information-based teaching methods is not the more the better,but an effective combination of corresponding information teaching methods should be explored instead,such as learning the formation of Mount Tai through 3D animation,learning the lithology of Mount Tai through VR,etc.,so that not only can students learn easily and efficiently,but the workload of teachers can be reduced as well.

基于C-mount封装的半导体激光器热特性模拟分析

通过对半导体激光器热特性以及散热方式的理论分析,建立了C-mount封装半导体激光器的物理散热模型,针对其在稳态工作条件下的热特性,利用ANSYS有限元软件进行了模拟分析,对ANSYS自建模与外部导入两种建模方式进行分析,发现自建模方式更加精确。通过改变C-mount热沉的厚度,得到了芯片温度的变化规律,并从热流的角度进行分析。最后,通过引入导热性能良好的金刚石膜与石墨烯膜,设计了一种较为理想的复式散热结构。

Conceptual design of automobile engine rubber mounting composite using TRIZ-Morphological chart-analytic network process technique

An engine rubber mounting is one of the important parts of a vehicle. It is a function to isolate or absorb and to reduce vibration to the vehicle body thus to the passenger itself. Due to the engine compartments environment such as heat and massive vibration due to road conditions, the engine rubber mountings lifespan has been reduced. Thus several studies have been conducted to upgrade the material lifespan to make it more reliable and better engine mounting components. This paper presents the conceptual design of kenaf fiber polymer as automotive engine rubber mounting composites using the integration of Theory of Inventive Problem Solving(TRIZ). In this early stage, the solution is generated using 40 inventive principles and TRIZ contradiction method. The solution parameter for the specific design character is the selected using the morphological chart to develop a systematic conceptual design for the component. Four(4) innovative design concepts were produced and Analytic Network Process(ANP)methods were utilized to perform the multi-criteria decision-making process of selecting the best concept design for the polymer composite engine rubber mounting component.