The cross sections of fragments produced in the 140 A MeV58,64Ni+9 Be projectile fragmentation reactions are calculated by using the antisymmetrized molecular dynamics (AMD) model, the modified statistical abrasion...The cross sections of fragments produced in the 140 A MeV58,64Ni+9 Be projectile fragmentation reactions are calculated by using the antisymmetrized molecular dynamics (AMD) model, the modified statistical abrasion- ablation (SAA) model, and the empirical EPAX2/EPAX3 formulae. The Gogny-gO interaction is taken as the effective nucleon-nucleon interaction in the AMD calculation, and the decays of fragments obtained from the AMD results are calculated by using the GEMINI code. The calculated cross sections of fragments are compared.展开更多
A model comparison based software testing method (MCST) is proposed. In this method, the requirements aria programs or software under test are transformed into the ones in the same form, and described by the same mo...A model comparison based software testing method (MCST) is proposed. In this method, the requirements aria programs or software under test are transformed into the ones in the same form, and described by the same model describe language (MDL). Then, the requirements are transformed into a specification model and the programs into an implementation model. Thus, the elements and structures of the two models are compared, and the differences between them are obtained. Based on the diffrences, a test suite is generated. Different MDLs can be chosen for the software under test. The usages of two classical MDLs in MCST, the equivalence classes model and the extended finite state machine (EFSM) model, are described with example applications. The results show that the test suites generated by MCST are more efficient and smaller than some other testing methods, such as the pathcoverage testing method, the object state diagram testing method, etc.展开更多
The establishment of crop yield estimating model based on microwave and optical satellite images can conduct the mutual verification of the accuracy of the reported crop yield and the precision of the estimating model...The establishment of crop yield estimating model based on microwave and optical satellite images can conduct the mutual verification of the accuracy of the reported crop yield and the precision of the estimating model. With Shou County and Huaiyuan County of Anhui Province as the experimental fields of winter wheat producing areas, the linear winter wheat yield estimating models were established by adopting backscattering coefficient and Normalized Difference Vegetation Index(NDVI) based on images from the synthetic aperture radar(SAR)—RDARSAT-2 and HJ satellite photographed in mid-April and early May, 2014, and then comparisons were conducted on the accuracy of the yield estimating models. The accuracies of the yield estimating models established using co-polarized(HH) and cross-polarized(HV) modes of SAR in Jiangou Town, Shou County were 68.37% and 74.01%, respectively, while the accuracies in Longkang Town, Huaiyuan County were 63.10%and 69.10%, respectively. Accuracies of yield estimating models established by HJ satellite data were 69.52% and 66.43% in Shou County and Huaiyuan County, respectively. Accuracies of winter yield estimating model based on HJ satellite data and that based on SAR were closed, and the yield difference of winter wheat in the lodging region was analyzed in detail. The model results laid the foundation and accumulated experience for the verification, parameters correction and promotion of the winter wheat yield estimating model.展开更多
Cloud Computing is an uprising technology in the rapid growing IT world. The adaptation of cloud computing is increasing in very large scale business organizations to small institutions rapidly due to many advanced fe...Cloud Computing is an uprising technology in the rapid growing IT world. The adaptation of cloud computing is increasing in very large scale business organizations to small institutions rapidly due to many advanced features of cloud computing, such as SaaS, PaaS and IaaS service models. So, nowadays, many organizations are trying to implement Cloud Computing based ERP system to enjoy the benefits of cloud computing. To implement any ERP system, an organization usually faces many challenges. As a result, this research has introduced how easily this cloud system can be implemented in an organization. By using this ERP system, an organization can be benefited in many ways;especially Small and Medium Enterprises (SMEs) can enjoy the highest possible benefits from this system.展开更多
Dry matter intake (DMI) prediction models of NRC (2001), Fox et aL (2004) and Fuentes-Pila et aL (2003) were targeted in the present study, and the objective was to evaluate their prediction accuracy with feed...Dry matter intake (DMI) prediction models of NRC (2001), Fox et aL (2004) and Fuentes-Pila et aL (2003) were targeted in the present study, and the objective was to evaluate their prediction accuracy with feeding trial data of 32 lactating Holstein cows fed two total mixed rations with different forage source. Thirty-two cows were randomly assigned to one of two total mixed ration groups: a ration containing a mixed forage (MF) of 3.7% Chinese wildrye, 28.4% alfalfa hay and 26.5% corn silage diet and another ration containing 33.8% corn stover (CS) as unique forage source. The actual DMI was greater in MF group than in CS group (P=0.064). The NRC model to predict DMI resulted in the lowest root mean square prediction error for both MF and CS groups (1.09 kg d-1 vs. 1.28 kg d-1) and the highest accuracy and precision based on concordance correlation coefficient for both MF and CS diet (0.89 vs. 0.87). Except the NRC model, the other two models presented mean and linear biases in both MF and CS diets when prediction residuals were plotted against predicted DMI values (P〈0.001). The DMI variation in MF was caused by week of lactation (55.6%), milk yield (13.9%), milk fat percentage (7.1%) and dietary neutral detergent fiber (13.3%), while the variation in CS was caused by week of lactation (50.9%), live body weight (28.2%), milk yield (8.4%), milk fat percentage (5.2%) and dietary neutral detergent fibre (3.8%). In a brief, the NRC model to predict DMI is comparatively acceptable for lactating dairy cows fed two total mixed rations with different forage source.展开更多
Background: Effective methods for managing patients with solitary pulmonary nodules(SPNs) depend critically on the predictive probability of malignancy.Methods: Between July 2009 and June 2011, data on gender, age...Background: Effective methods for managing patients with solitary pulmonary nodules(SPNs) depend critically on the predictive probability of malignancy.Methods: Between July 2009 and June 2011, data on gender, age, cancer history, tumor familial history, smoking status, tumor location, nodule size, spiculation, calcification, the tumor border, and the final pathological diagnosis were collected retrospectively from 154 surgical patients with an SPN measuring 3-30 mm. Each final diagnosis was compared with the probability calculated by three predicted models—the Mayo, VA, and Peking University(PU) models. The accuracy of each model was assessed using area under the receiver operating characteristics(ROC) and calibration curves.Results: The area under the ROC curve of the PU model [0.800; 95% confidence interval(CI): 0.708-0.891] was higher than that of the Mayo model(0.753; 95% CI: 0.650-0.857) or VA model(0.728; 95% CI: 0.623-0.833); however, this finding was not statistically significant. To varying degrees, calibration curves showed that all three models overestimated malignancy.Conclusions: The three predicted models have similar accuracy for prediction of SPN malignancy, although the accuracy is not sufficient. For Chinese patients, the PU model may has greater predictive power.Background: Here, we introduced our short experience on the application of a new CUSA Excel ultrasonic aspiration system, which was provided by Integra Lifesciences corporation, in skull base meningiomas resection.Methods: Ten patients with anterior, middle skull base and sphenoid ridge meningioma were operated using the CUSA Excel ultrasonic aspiration system at the Neurosurgery Department of Shanghai Huashan Hospital from August 2014 to October 2014. There were six male and four female patients, aged from 38 to 61 years old(the mean age was 48.5 years old). Five cases with tumor located at anterior skull base, three cases with tumor on middle skull base, and two cases with tumor on sphenoid ridge.Results: All the patents received total resection of meningiomas with the help of this new tool, and the critical brain vessels and nerves were preserved during operations. All the patients recovered well after operation.Conclusions: This new CUSA Excel ultrasonic aspiration system has the advantage of preserving vital brain arteries and cranial nerves during skull base meningioma resection, which is very important for skull base tumor operations. This key step would ensure a well prognosis for patients. We hope the neurosurgeons would benefit from this kind of technique.Background: The purposes of this study were to explore the effects of high mobility group protein box 1(HMGB1) gene on the growth, proliferation, apoptosis, invasion, and metastasis of glioma cells, with an attempt to provide potential therapeutic targets for the treatment of glioma. Methods: The expressions of HMGB1 in glioma cells(U251, U-87 MG and LN-18) and one control cell line(SVG p12) were detected by real time PCR and Western blotting, respectively. Then, the effects of HMGB1 on the biological behaviors of glioma cells were detected: the expression of HMGB1 in human glioma cell lines U251 and U-87 MG were suppressed using RNAi technique, then the influences of HMGB1 on the viability, cycle, apoptosis, and invasion abilities of U251 and U-87 MG cells were analyzed using in a Transwell invasion chamber. Also, the effects of HMGB1 on the expressions of cyclin D1, Bax, Bcl-2, and MMP 9 were detected. Results: As shown by real-time PCR and Western blotting, the expression of HMGB1 significantly increased in glioma cells(U251, U-87 MG, and LN-18) in comparison with the control cell line(SVG p12); the vitality, proliferation and invasive capabilities of U251 and U-87 MG cells in the HMGB1 siR NA-transfected group were significantly lower than those in the blank control group and negative control(NC) siR NA group(P〈0.05) but showed no significant difference between the blank control group and NC siR NA group. The percentage of apoptotic U251 and U-87 MG cells was significantly higher in the HMGB1 siR NA-transfected group than in the blank control group and NC siR NA group(P〈0.05) but was similar between the latter two groups. The HMGB1 siR NA-transfected group had significantly lower expression levels of Cyclin D1, Bcl-2, and MMP-9 protein in U251 and U-87 MG cells and significantly higher expression of Bax protein than in the blank control group and NC siR NA group(P〈0.05); the expression profiles of cyclin D1, Bax, Bcl-2, and MMP 9 showed no significant change in both blank control group and NC siR NA group. Conclusions: HMGB1 gene may promote the proliferation and migration of glioma cells and suppress its effects of apoptosis. Inhibition of the expression of HMGB1 gene can suppress the proliferation and migration of glioma cells and promote their apoptosis. Our observations provided a new target for intervention and treatment of glioma.展开更多
Potential evapotranspiration(EPET)is usually calculated by empirical methods from surface meteorological variables,such as temperature,radiation and wind speed.The in-situ measured pan evaporation(ETpan)can also be us...Potential evapotranspiration(EPET)is usually calculated by empirical methods from surface meteorological variables,such as temperature,radiation and wind speed.The in-situ measured pan evaporation(ETpan)can also be used as a proxy for EPET.In this study,EPET values computed from ten models are compared with observed ETpan data in ten Chinese river basins for the period 1961−2013.The daily observed meteorological variables at 2267 stations are used as the input to those models,and a ranking scheme is applied to rank the statistical quantities(ratio of standard deviations,correlation coefficient,and ratio of trends)between ETpan and modeled EPET in different river basins.There are large deviations between the modeled EPET and the ETpan in both the magnitude and the annual trend at most stations.In eight of the basins(except for Southeast and Southwest China),ETpan shows decreasing trends with magnitudes ranging between−0.01 mm d−1 yr−1 and−0.03 mm d−1 yr−1,while the decreasing trends in modeled EPET are less than−0.01 mm d−1 yr−1.Inter comparisons among different models in different river basins suggest that PETHam1 is the best model in the Pearl River basin,PETHam2 outperforms other models in the Huaihe River,Yangtze River and Yellow River basins,and PETFAO is the best model for the remaining basins.Sensitivity analyses reveal that wind speed and sunshine duration are two important factors for decreasing EPET in most basins except in Southeast and Southwest China.The increasing EPET trend in Southeast China is mainly attributed to the reduced relative humidity.展开更多
The margin of the Tibetan Plateau of Southwest China is one of the most seismically active regions of China and is the location of the China Seismic Experimental Site(CSES).Many studies have developed seismic velocity...The margin of the Tibetan Plateau of Southwest China is one of the most seismically active regions of China and is the location of the China Seismic Experimental Site(CSES).Many studies have developed seismic velocity models of Southwest China,but few have compared and evaluated these models which is important for further model improvement.Thus,we compared six published seismic shear-wave velocity models of Southwest China on absolute velocity and velocity perturbation patterns.The models are derived from different types of data(e.g.,surface waves from ambient noise and earthquakes,body-wave travel times,receiver functions) and inversion methods.We interpolated the models into a uniform horizontal grid(0.5° × 0.5°) and vertically sampled them at 5,10,20,30,40,and 60 km depths.We found significant differences between the six models.Then,we selected three of them that showed greater consistency for further comparison.Our further comparisons revealed systematic biases between models in absolute velocity that may be related to different data types.The perturbation pattern of the model is especially divergent in the shallow part,but more consistent in the deep part.We conducted synthetic and inversion tests to explore possible causes and our results imply that systematic differences between the data,differences in methods,and other factors may directly affect the model.Therefore,the Southwest China velocity model still has considerable room for improvement,and the impact of inconsistency between different data types on the model needs further research.Finally,we proposed a new reference shear-wave velocity model of Southwest China(SwCM-S1.0) based on the three selected models with high consistency.We believe that this model is a better representation of more robust features of the models that are based on different data sets.展开更多
The monsoon intraseasonal oscillation(MISO)is the dominant variability over the Indian Ocean during the Indian summer monsoon(ISM)season and is characterized by pronounced northward propagation.Previous studies have s...The monsoon intraseasonal oscillation(MISO)is the dominant variability over the Indian Ocean during the Indian summer monsoon(ISM)season and is characterized by pronounced northward propagation.Previous studies have shown that general circulation models(GCMs)still have difficulty in simulating the northwardpropagating MISO,and that the role of air-sea interaction in MISO is unclear.In this study,14 atmosphere-ocean coupled GCMs(CGCMs)and the corresponding atmosphere-only GCMs(AGCMs)are selected from Phase 6 of the Coupled Model Intercomparison Project(CMIP6)to assess their performance in reproducing MISO and the associated vortex tilting mechanism.The results show that both CGCMs and AGCMs are able to well simulate the significant relationship between MISO and vortex tilting.However,80%of CGCMs show better simulation skills for MISO than AGCMs in CMIP6.In AGCMs,the poor model fidelity in MISO is due to the failure simulation of vortex tilting.Moreover,it is found that failure to simulate the downward motion to the north of convection is responsible for the poor simulation of vortex tilting in AGCMs.In addition,it is observed that there is a significant relationship between the simulated sea surface temperature gradient and simulated vertical velocity shear in the meridional direction.These findings indicate that air-sea interaction may play a vital role in simulating vertical motions in tilting and MISO processes.This work offers us a specific target to improve the MISO simulation and further studies are needed to elucidate the physical processes of this air-sea interaction coupling with vortex tilting.展开更多
In this paper, the many indices used in validation of crop models, such as RMSE (root mean square errors), Sd (standard error of absolute difference), da (mean absolute difference), dap (ratio of da to the mean...In this paper, the many indices used in validation of crop models, such as RMSE (root mean square errors), Sd (standard error of absolute difference), da (mean absolute difference), dap (ratio of da to the mean observation), r (correlation), and R2 (determination coefficient), are compared for the same rice architectural parameter model, and their advantages and disadvantages are analyzed. A new index for validation of crop models, dap between the observed and the simulated values, is proposed, with dap〈5% as the suggested standard for precision of crop models. The different kinds of validation methods in crop models should be combined in the following aspects:(1) calculating da and dap; (2) calculating the RMSE or Sd; (3) calculating r and R2, at the same time, plotting 1:1 diagram.展开更多
Jerome Model and Horace Model are the two influential translation models in the translation field. This article tries to find the similarities and differences between these two models.
Compound Poisson risk model has been simulated. It has started with exponential claim sizes. The simulations have checked for infinite ruin probabilities. An appropriate time window has been chosen to estimate and com...Compound Poisson risk model has been simulated. It has started with exponential claim sizes. The simulations have checked for infinite ruin probabilities. An appropriate time window has been chosen to estimate and compare ruin probabilities. The infinite ruin probabilities of two-compound Poisson risk process have estimated and compared them with standard theoretical results.展开更多
基金Supported by the Program for Science and Technology Innovation Talents in Universities of Henan Province under Grant No13HASTIT046
文摘The cross sections of fragments produced in the 140 A MeV58,64Ni+9 Be projectile fragmentation reactions are calculated by using the antisymmetrized molecular dynamics (AMD) model, the modified statistical abrasion- ablation (SAA) model, and the empirical EPAX2/EPAX3 formulae. The Gogny-gO interaction is taken as the effective nucleon-nucleon interaction in the AMD calculation, and the decays of fragments obtained from the AMD results are calculated by using the GEMINI code. The calculated cross sections of fragments are compared.
基金The National Natural Science Foundationof Hubei Province (No.2005ABA266)
文摘A model comparison based software testing method (MCST) is proposed. In this method, the requirements aria programs or software under test are transformed into the ones in the same form, and described by the same model describe language (MDL). Then, the requirements are transformed into a specification model and the programs into an implementation model. Thus, the elements and structures of the two models are compared, and the differences between them are obtained. Based on the diffrences, a test suite is generated. Different MDLs can be chosen for the software under test. The usages of two classical MDLs in MCST, the equivalence classes model and the extended finite state machine (EFSM) model, are described with example applications. The results show that the test suites generated by MCST are more efficient and smaller than some other testing methods, such as the pathcoverage testing method, the object state diagram testing method, etc.
基金Supported by the National Natural Science Foundation of China(41205126)the Discipline Construction and Macroscopic Agricultural Research Project of Anhui Academy of Agricultural Sciences(13A1424)+2 种基金the Fund for Youth Innovation of Anhui Academy of Agricultural Sciences(14B1460)the Innovative Research Team for Agricultural Disaster Risk Analysis in Anhui ProvinceAnhui Academy of Agricultural Sciences(14C1409)~~
文摘The establishment of crop yield estimating model based on microwave and optical satellite images can conduct the mutual verification of the accuracy of the reported crop yield and the precision of the estimating model. With Shou County and Huaiyuan County of Anhui Province as the experimental fields of winter wheat producing areas, the linear winter wheat yield estimating models were established by adopting backscattering coefficient and Normalized Difference Vegetation Index(NDVI) based on images from the synthetic aperture radar(SAR)—RDARSAT-2 and HJ satellite photographed in mid-April and early May, 2014, and then comparisons were conducted on the accuracy of the yield estimating models. The accuracies of the yield estimating models established using co-polarized(HH) and cross-polarized(HV) modes of SAR in Jiangou Town, Shou County were 68.37% and 74.01%, respectively, while the accuracies in Longkang Town, Huaiyuan County were 63.10%and 69.10%, respectively. Accuracies of yield estimating models established by HJ satellite data were 69.52% and 66.43% in Shou County and Huaiyuan County, respectively. Accuracies of winter yield estimating model based on HJ satellite data and that based on SAR were closed, and the yield difference of winter wheat in the lodging region was analyzed in detail. The model results laid the foundation and accumulated experience for the verification, parameters correction and promotion of the winter wheat yield estimating model.
文摘Cloud Computing is an uprising technology in the rapid growing IT world. The adaptation of cloud computing is increasing in very large scale business organizations to small institutions rapidly due to many advanced features of cloud computing, such as SaaS, PaaS and IaaS service models. So, nowadays, many organizations are trying to implement Cloud Computing based ERP system to enjoy the benefits of cloud computing. To implement any ERP system, an organization usually faces many challenges. As a result, this research has introduced how easily this cloud system can be implemented in an organization. By using this ERP system, an organization can be benefited in many ways;especially Small and Medium Enterprises (SMEs) can enjoy the highest possible benefits from this system.
基金financially supported by the National Natural Science Foundation of China(31572435)the National Key Research and Development Plan(2016YFD0700205,2016YFD0700201)
文摘Dry matter intake (DMI) prediction models of NRC (2001), Fox et aL (2004) and Fuentes-Pila et aL (2003) were targeted in the present study, and the objective was to evaluate their prediction accuracy with feeding trial data of 32 lactating Holstein cows fed two total mixed rations with different forage source. Thirty-two cows were randomly assigned to one of two total mixed ration groups: a ration containing a mixed forage (MF) of 3.7% Chinese wildrye, 28.4% alfalfa hay and 26.5% corn silage diet and another ration containing 33.8% corn stover (CS) as unique forage source. The actual DMI was greater in MF group than in CS group (P=0.064). The NRC model to predict DMI resulted in the lowest root mean square prediction error for both MF and CS groups (1.09 kg d-1 vs. 1.28 kg d-1) and the highest accuracy and precision based on concordance correlation coefficient for both MF and CS diet (0.89 vs. 0.87). Except the NRC model, the other two models presented mean and linear biases in both MF and CS diets when prediction residuals were plotted against predicted DMI values (P〈0.001). The DMI variation in MF was caused by week of lactation (55.6%), milk yield (13.9%), milk fat percentage (7.1%) and dietary neutral detergent fiber (13.3%), while the variation in CS was caused by week of lactation (50.9%), live body weight (28.2%), milk yield (8.4%), milk fat percentage (5.2%) and dietary neutral detergent fibre (3.8%). In a brief, the NRC model to predict DMI is comparatively acceptable for lactating dairy cows fed two total mixed rations with different forage source.
基金granted by the initiative research scheme for college student, Guangdong, China (No. 1212110046)
文摘Background: Effective methods for managing patients with solitary pulmonary nodules(SPNs) depend critically on the predictive probability of malignancy.Methods: Between July 2009 and June 2011, data on gender, age, cancer history, tumor familial history, smoking status, tumor location, nodule size, spiculation, calcification, the tumor border, and the final pathological diagnosis were collected retrospectively from 154 surgical patients with an SPN measuring 3-30 mm. Each final diagnosis was compared with the probability calculated by three predicted models—the Mayo, VA, and Peking University(PU) models. The accuracy of each model was assessed using area under the receiver operating characteristics(ROC) and calibration curves.Results: The area under the ROC curve of the PU model [0.800; 95% confidence interval(CI): 0.708-0.891] was higher than that of the Mayo model(0.753; 95% CI: 0.650-0.857) or VA model(0.728; 95% CI: 0.623-0.833); however, this finding was not statistically significant. To varying degrees, calibration curves showed that all three models overestimated malignancy.Conclusions: The three predicted models have similar accuracy for prediction of SPN malignancy, although the accuracy is not sufficient. For Chinese patients, the PU model may has greater predictive power.Background: Here, we introduced our short experience on the application of a new CUSA Excel ultrasonic aspiration system, which was provided by Integra Lifesciences corporation, in skull base meningiomas resection.Methods: Ten patients with anterior, middle skull base and sphenoid ridge meningioma were operated using the CUSA Excel ultrasonic aspiration system at the Neurosurgery Department of Shanghai Huashan Hospital from August 2014 to October 2014. There were six male and four female patients, aged from 38 to 61 years old(the mean age was 48.5 years old). Five cases with tumor located at anterior skull base, three cases with tumor on middle skull base, and two cases with tumor on sphenoid ridge.Results: All the patents received total resection of meningiomas with the help of this new tool, and the critical brain vessels and nerves were preserved during operations. All the patients recovered well after operation.Conclusions: This new CUSA Excel ultrasonic aspiration system has the advantage of preserving vital brain arteries and cranial nerves during skull base meningioma resection, which is very important for skull base tumor operations. This key step would ensure a well prognosis for patients. We hope the neurosurgeons would benefit from this kind of technique.Background: The purposes of this study were to explore the effects of high mobility group protein box 1(HMGB1) gene on the growth, proliferation, apoptosis, invasion, and metastasis of glioma cells, with an attempt to provide potential therapeutic targets for the treatment of glioma. Methods: The expressions of HMGB1 in glioma cells(U251, U-87 MG and LN-18) and one control cell line(SVG p12) were detected by real time PCR and Western blotting, respectively. Then, the effects of HMGB1 on the biological behaviors of glioma cells were detected: the expression of HMGB1 in human glioma cell lines U251 and U-87 MG were suppressed using RNAi technique, then the influences of HMGB1 on the viability, cycle, apoptosis, and invasion abilities of U251 and U-87 MG cells were analyzed using in a Transwell invasion chamber. Also, the effects of HMGB1 on the expressions of cyclin D1, Bax, Bcl-2, and MMP 9 were detected. Results: As shown by real-time PCR and Western blotting, the expression of HMGB1 significantly increased in glioma cells(U251, U-87 MG, and LN-18) in comparison with the control cell line(SVG p12); the vitality, proliferation and invasive capabilities of U251 and U-87 MG cells in the HMGB1 siR NA-transfected group were significantly lower than those in the blank control group and negative control(NC) siR NA group(P〈0.05) but showed no significant difference between the blank control group and NC siR NA group. The percentage of apoptotic U251 and U-87 MG cells was significantly higher in the HMGB1 siR NA-transfected group than in the blank control group and NC siR NA group(P〈0.05) but was similar between the latter two groups. The HMGB1 siR NA-transfected group had significantly lower expression levels of Cyclin D1, Bcl-2, and MMP-9 protein in U251 and U-87 MG cells and significantly higher expression of Bax protein than in the blank control group and NC siR NA group(P〈0.05); the expression profiles of cyclin D1, Bax, Bcl-2, and MMP 9 showed no significant change in both blank control group and NC siR NA group. Conclusions: HMGB1 gene may promote the proliferation and migration of glioma cells and suppress its effects of apoptosis. Inhibition of the expression of HMGB1 gene can suppress the proliferation and migration of glioma cells and promote their apoptosis. Our observations provided a new target for intervention and treatment of glioma.
基金supported by the National Natural Science Foundation of China(Grant No.41875106)the National Key R&D Program of China(Grant No.2016YFA0602401)。
文摘Potential evapotranspiration(EPET)is usually calculated by empirical methods from surface meteorological variables,such as temperature,radiation and wind speed.The in-situ measured pan evaporation(ETpan)can also be used as a proxy for EPET.In this study,EPET values computed from ten models are compared with observed ETpan data in ten Chinese river basins for the period 1961−2013.The daily observed meteorological variables at 2267 stations are used as the input to those models,and a ranking scheme is applied to rank the statistical quantities(ratio of standard deviations,correlation coefficient,and ratio of trends)between ETpan and modeled EPET in different river basins.There are large deviations between the modeled EPET and the ETpan in both the magnitude and the annual trend at most stations.In eight of the basins(except for Southeast and Southwest China),ETpan shows decreasing trends with magnitudes ranging between−0.01 mm d−1 yr−1 and−0.03 mm d−1 yr−1,while the decreasing trends in modeled EPET are less than−0.01 mm d−1 yr−1.Inter comparisons among different models in different river basins suggest that PETHam1 is the best model in the Pearl River basin,PETHam2 outperforms other models in the Huaihe River,Yangtze River and Yellow River basins,and PETFAO is the best model for the remaining basins.Sensitivity analyses reveal that wind speed and sunshine duration are two important factors for decreasing EPET in most basins except in Southeast and Southwest China.The increasing EPET trend in Southeast China is mainly attributed to the reduced relative humidity.
基金supported by Open Fund from Sino Probe Laboratory (No. Sinoprobe Lab 202201)the National Natural Science Foundation of China (No. U1939204)the Special Fund of the Institute of Geophysics, China Earthquake Administration (No. DQJB21B32)
文摘The margin of the Tibetan Plateau of Southwest China is one of the most seismically active regions of China and is the location of the China Seismic Experimental Site(CSES).Many studies have developed seismic velocity models of Southwest China,but few have compared and evaluated these models which is important for further model improvement.Thus,we compared six published seismic shear-wave velocity models of Southwest China on absolute velocity and velocity perturbation patterns.The models are derived from different types of data(e.g.,surface waves from ambient noise and earthquakes,body-wave travel times,receiver functions) and inversion methods.We interpolated the models into a uniform horizontal grid(0.5° × 0.5°) and vertically sampled them at 5,10,20,30,40,and 60 km depths.We found significant differences between the six models.Then,we selected three of them that showed greater consistency for further comparison.Our further comparisons revealed systematic biases between models in absolute velocity that may be related to different data types.The perturbation pattern of the model is especially divergent in the shallow part,but more consistent in the deep part.We conducted synthetic and inversion tests to explore possible causes and our results imply that systematic differences between the data,differences in methods,and other factors may directly affect the model.Therefore,the Southwest China velocity model still has considerable room for improvement,and the impact of inconsistency between different data types on the model needs further research.Finally,we proposed a new reference shear-wave velocity model of Southwest China(SwCM-S1.0) based on the three selected models with high consistency.We believe that this model is a better representation of more robust features of the models that are based on different data sets.
基金The Zhejiang Provincial Natural Science Foundation of China under contract No.LR19D060001the Scientific Research Fund of the Second Institute of Oceanography,Ministry of Natural Resources,under contract No.JB2206+1 种基金the China Postdoctoral Science Foundation under contract Nos 2022M711010 and 2021M703792the National Natural Science Foundation of China under contract No.42106003。
文摘The monsoon intraseasonal oscillation(MISO)is the dominant variability over the Indian Ocean during the Indian summer monsoon(ISM)season and is characterized by pronounced northward propagation.Previous studies have shown that general circulation models(GCMs)still have difficulty in simulating the northwardpropagating MISO,and that the role of air-sea interaction in MISO is unclear.In this study,14 atmosphere-ocean coupled GCMs(CGCMs)and the corresponding atmosphere-only GCMs(AGCMs)are selected from Phase 6 of the Coupled Model Intercomparison Project(CMIP6)to assess their performance in reproducing MISO and the associated vortex tilting mechanism.The results show that both CGCMs and AGCMs are able to well simulate the significant relationship between MISO and vortex tilting.However,80%of CGCMs show better simulation skills for MISO than AGCMs in CMIP6.In AGCMs,the poor model fidelity in MISO is due to the failure simulation of vortex tilting.Moreover,it is found that failure to simulate the downward motion to the north of convection is responsible for the poor simulation of vortex tilting in AGCMs.In addition,it is observed that there is a significant relationship between the simulated sea surface temperature gradient and simulated vertical velocity shear in the meridional direction.These findings indicate that air-sea interaction may play a vital role in simulating vertical motions in tilting and MISO processes.This work offers us a specific target to improve the MISO simulation and further studies are needed to elucidate the physical processes of this air-sea interaction coupling with vortex tilting.
基金supported by the National High-Tech R&D Program (2006AA10Z230,2006AA10Z219-1)the National Natural Science Foundation of China (31171455)+3 种基金the Jiangsu Province Agricultural Scientific Technology Innovation Fund, China (CX(10)221, CX (11)2042)the Agricultural Scientific Technology Support Program, Jiangsu Province, China (BE2008397,BE2011342)the No-Profit Industry (Meteorology) Research Program, China (GYHY201006027, GYHY201106027)the Jiangsu Government Scholarship for Overseas Studies, China
文摘In this paper, the many indices used in validation of crop models, such as RMSE (root mean square errors), Sd (standard error of absolute difference), da (mean absolute difference), dap (ratio of da to the mean observation), r (correlation), and R2 (determination coefficient), are compared for the same rice architectural parameter model, and their advantages and disadvantages are analyzed. A new index for validation of crop models, dap between the observed and the simulated values, is proposed, with dap〈5% as the suggested standard for precision of crop models. The different kinds of validation methods in crop models should be combined in the following aspects:(1) calculating da and dap; (2) calculating the RMSE or Sd; (3) calculating r and R2, at the same time, plotting 1:1 diagram.
文摘Jerome Model and Horace Model are the two influential translation models in the translation field. This article tries to find the similarities and differences between these two models.
文摘Compound Poisson risk model has been simulated. It has started with exponential claim sizes. The simulations have checked for infinite ruin probabilities. An appropriate time window has been chosen to estimate and compare ruin probabilities. The infinite ruin probabilities of two-compound Poisson risk process have estimated and compared them with standard theoretical results.