A new and simple route for the synthesis of α,β-unsaturated ketones via cleavage of the C-C(O)C single bond of monoalkylated β-diketone has been described. The reaction was catalyzed by copper, a cheap transition m...A new and simple route for the synthesis of α,β-unsaturated ketones via cleavage of the C-C(O)C single bond of monoalkylated β-diketone has been described. The reaction was catalyzed by copper, a cheap transition metal in a weakly basic medium (K<sub>3</sub>PO<sub>4</sub>) at room temperature. To carry out this study, we first had to synthesize the monoalkylated β-diketones 1. Afterwards, α,β-unsaturated ketones 2 were obtained with high yields around 80%. Finally, all the products were characterized by 1H NMR, 13C NMR, and HRMS spectra. .展开更多
Four monoalkyl esters of isoalkylphosphonic acids have been studied for the chromatographic separation of rare earths (RE).The relationship between distribution ratios and acid concentration of the eluants for samariu...Four monoalkyl esters of isoalkylphosphonic acids have been studied for the chromatographic separation of rare earths (RE).The relationship between distribution ratios and acid concentration of the eluants for samarium and ytterbium has been explored.The characteristics of these extractants loaded onto macroreticular poly (methyl methacrylate) resin beads for the separation of lanthanum,cerium,praseodymium and neodymium have been compared.Among the extractants studied,mono(1-methylheptyl) ester of isooctylphosphonic acid was found to be the best for RE separation.The acidity for separation is lower than any known P-containing extractants for the same purpose.For instance,with 1.73 mol·L^(-1) nitric acid as eluent,thulium,ytterbium and lutetium can be separated quantitatively.The extractant-loaded resins possess high column efficiency with good kinetic characteristics.The extraction mechanism was also explored.展开更多
New structural phospholipids 1.3-cyclic monoalkyl(acyl)-rac-glycerothiophosphates of uridine were synthesized. The strategy for the synthesis is using hexaethylphosphorous triamide, activated by a catalytic amount of ...New structural phospholipids 1.3-cyclic monoalkyl(acyl)-rac-glycerothiophosphates of uridine were synthesized. The strategy for the synthesis is using hexaethylphosphorous triamide, activated by a catalytic amount of iodine, as the phosphorylating reagent. Their structures were confirmed by (1)HNMR, (31)PNMR, IR and elemental analysis.展开更多
文摘A new and simple route for the synthesis of α,β-unsaturated ketones via cleavage of the C-C(O)C single bond of monoalkylated β-diketone has been described. The reaction was catalyzed by copper, a cheap transition metal in a weakly basic medium (K<sub>3</sub>PO<sub>4</sub>) at room temperature. To carry out this study, we first had to synthesize the monoalkylated β-diketones 1. Afterwards, α,β-unsaturated ketones 2 were obtained with high yields around 80%. Finally, all the products were characterized by 1H NMR, 13C NMR, and HRMS spectra. .
基金The project supported by the National Natural Science Foundation of China
文摘Four monoalkyl esters of isoalkylphosphonic acids have been studied for the chromatographic separation of rare earths (RE).The relationship between distribution ratios and acid concentration of the eluants for samarium and ytterbium has been explored.The characteristics of these extractants loaded onto macroreticular poly (methyl methacrylate) resin beads for the separation of lanthanum,cerium,praseodymium and neodymium have been compared.Among the extractants studied,mono(1-methylheptyl) ester of isooctylphosphonic acid was found to be the best for RE separation.The acidity for separation is lower than any known P-containing extractants for the same purpose.For instance,with 1.73 mol·L^(-1) nitric acid as eluent,thulium,ytterbium and lutetium can be separated quantitatively.The extractant-loaded resins possess high column efficiency with good kinetic characteristics.The extraction mechanism was also explored.
文摘New structural phospholipids 1.3-cyclic monoalkyl(acyl)-rac-glycerothiophosphates of uridine were synthesized. The strategy for the synthesis is using hexaethylphosphorous triamide, activated by a catalytic amount of iodine, as the phosphorylating reagent. Their structures were confirmed by (1)HNMR, (31)PNMR, IR and elemental analysis.
