人工法off-line HDF对血液透析充分性和高同型半胱氨酸血症的影响

目的探究人工法off-line HDF对维持性血液透析(MHD)患者透析充分性、高同型半胱氨酸血症(HHcy)的影响。方法随机选取2021至2023年于南昌大学第一附属高新医院血液透析中心稳定透析6个月以上的MHD患者30例,进行单中心自身对照研究,时长6个月。前3个月维持每周2次高通量血液透析(HFHD)联合1次on-line HDF,后3个月维持每周2次人工法off-line HDF联合1次on-line HDF。于研究第3个月、第6个月时用全自动生化分析仪检测透析前后血尿素氮(BUN)、血肌酐(SCr)、β2-微球蛋白(β2MG)、同型半胱氨酸(Hcy)、白蛋白(Alb)、C反应蛋白(CRP)、血红蛋白(Hb)、甲状旁腺素(iPTH)、磷(P)、钾(K)水平;计算血清尿素清除指数(Kt/V)、尿素下降率(URR)和β2MG清除率。结果人工法off-line HDF模式透析的Kt/V、URR及β2MG清除率均较显著高于HFHD模式透析(P<0.05);人工法off-lineHDF模式透析Kt/V、URR及β2MG清除率达到透析充分的百分率分别为83.33%、83.33%和93.33%,均显著高于HFHD模式透析(P<0.05)。与HFHD模式透析时相比,人工法off-lineHDF模式透析结束后,患者透析前Hcy水平降低,Alb水平升高(P<0.05)。结论人工法off-line HDF模式透析可显著增加Kt/V、URR和β2MG清除率,提高MHD患者的透析充分性达标率,且对HHcy具有改善作用。

Impact of Sedation Protocols on Elderly Patients Undergoing Mechanical Ventilation and Off-Line Weaning

The proportion of elderly patients in intensive care is increasing, and a significant proportion of them require mechanical ventilation. How to implement safe and effective mechanical ventilation for elderly patients, and when appropriate off-line is an important issue in the field of critical care medicine. Appropriate sedation can improve patient outcomes, but excessive sedation may lead to prolonged mechanical ventilation and increase the risk of complications. Elderly patients should be closely monitored and evaluated on an individual basis while offline, and the sedation regimen should be dynamically adjusted. This requires the healthcare team to consider the patient’s sedation needs, disease status, and pharmacodynamics and pharmacokinetics of the drug to arrive at the best strategy. Although the current research has provided valuable insights and strategies for sedation and off-line management, there are still many problems to be further explored and solved.

Effects of on-line solution and off-line heat treatment on microstructure and hardness of die-cast AZ91D alloy

The effects of on-line solution, off-line solution and aging heat treatment on the microstructure and hardness of the die-cast AZ91D alloys were investigated. Brinell hardness of die-cast AZ91D alloy increases through on-line solution and off-line aging treatment but decreases after off-line solution treatment. By X-ray diffractometry, optical microscopy, differential thermal analysis, scanning electron microscopy and X-ray energy dispersive spectroscopy, it is found that the microstructures of the die-cast AZ91D magnesium alloy before and after on-line solution and off-line aging are similar, consisting of α-Mg and β-Al12Mg17. The precipitation of Al element is prevented by on-line solution so that the effect of solid solution strengthening is enhanced. The β-Al12Mg17 phases precipitate from supersaturated Mg solid solution after off-line aging treatment, and lead to microstructure refinement of AZ91D alloy, so the effect of precipitation hardening is enhanced. The β-Al12Mg17 phases dissolve in the substructure after off-line solution treatment, which leads to that the grain boundary strengthening phase is reduced significantly and the hardness of die cast AZ91D is reduced.

分布式水文-土壤-植被模式的改进及气候水文Off-line模拟试验

文中对引进的高分辨率 (94 2 .5m× 94 2 .5m)分布式水文 土壤 植被模式 (DHSVM) ,针对海、滦河流域的特点进行了改进 ,主要包括 :(1)改变蒸散发模拟方法 ,用改进的Penman Monteith模式模拟海滦河流域的蒸发 ,较好地模拟出 1a内的两个峰值 ,最大值出现在 4～ 6月 ,次大值出现在 7～ 8月 ;(2 )改变水文模式结构 ,用多站点气候观测资料内插到模式网格点 ,充分实现了分布式水文模拟 ;(3)发展新的水文、植被、土壤参数化方案 ,对 33个参数分区计算和确定 ,并重点对土壤孔隙度 φ、土壤蓄水能力θfc、叶面指数LAI、随机阻抗γs 等 11个参数进行调试和修订 ,提高了水文模拟精度。用改进的DHSVM模式分别对滦河、桑干河流域蒸散发、地下水位、土壤湿度、土壤水下渗、产流、汇流与径流等水文过程进行Off line模拟试验 ,模拟结果与实测值一致性较好 ,滦河流域 1979～ 1991年、桑干河流域 1979～ 1987年水文模拟效率系数分别为 0 .89和 0 .82 。

A Land Surface Model(IAP94) for Climate Studies PartI:Formulation and Validation in Off-line Experiments

The IAP (Institute of Atmospheric Physics) land-surface model (IAP94) is described. This model is a comprehensive one with detailed description for the processes of vegetation, snow and soil. Particular attention has been paid to the cases with three water phases in the surface media. On the basis of the mixture theory and the theory of fluid dynamics of porous media, the system of universal conservational equations for water and heat of soil, snow and vegetation canopy has been constructed. On this background, all important factors that may affect the water and heat balance in media can be considered naturally, and each factor and term possess distinct physical meaning. In the computation of water content and temperature, the water phase change and the heat transportation by water flow are taken into account. Moreover, particular attention has been given to the water vapor diffusion in soil for arid or semi-arid cases, and snow compaction. In the treatment of surface turbulent fluxes, the difference between aerodynamic and thermal roughness is taken into account. The aerodynamic roughness of vegetation is calculated as a function of canopy density, height and zero-plane displacement. An extrapolation of log linear and exponential relationship is used when calculating the wind profile within canopy. The model has been validated against field measurements in off-line simulations. The desirable model′s performance leads to the conclusion that the IAP94 is able to reproduce the main physical mechanisms governing the energy and water balances in the global land surface. Part II of the present study will concern the validation in a 3-D experiment coupled with the IAP Two-Level AGCM.

Designing and Optimization of an Off-line Programming System for Robotic Belt Grinding Process

Off-line programming （OLP） system becomes one of the most important programming modules for the robotic belt grinding process, however there lacks research on increasing the grinding dexterous space depending on the OLP system. A new type of grinding robot and a novel robotic belt grinding workcell are forwarded, and their features are briefly introduced. An open and object-oriented off-line programming system is developed for this robotic belt grinding system. The parameters of the trimmed surface are read from the initial graphics exchange specification （IGES） file of the CAD model of the workpiece. The deBoor-Cox basis function is used to sample the grinding target with local contact frame on the workpiece. The numerical formula of inverse kinematics is set up based on Newton＇s iterative procedure, to calculate the grinding robot configurations corresponding to the grinding targets. After the grinding path is obtained, the OLP system turns to be more effective than the teach-by-showing system. In order to improve the grinding workspace, an optimization algorithm for dynamic tool frame is proposed and performed on the special robotic belt grinding system. The initial tool frame and the interval of neighboring tool frames are defined as the preparation of the algorithm. An optimized tool local frame can be selected to grind the complex surface for a maximum dexterity index of the robot. Under the optimization algorithm, a simulation of grinding a vane is included and comparison of grinding workspace is done before and after the tool frame optimization. By the algorithm, the grinding workspace can be enlarged. Moreover the dynamic tool frame can be considered to add one degree-of-freedom to the grinding kinematical chain, which provides the theoretical support for the improvement of robotic dexterity for the complex surface grinding.

An off-line simulation of land surface processes over the northern Tibetan Plateau

In order to further understand the land surface processes over the northern Tibetan Plateau, this study produced an off-line simulated examination at the Bujiao site on the northern Tibetan Plateau from June 2002 to April 2004, using the Noah Land Surface Model （Noah LSM） and observed data from the CAMP/Tibet experiment. The observed data were neces- sarily corrected and the number of soil layers in the Noah LSM was changed from 4 to 10 to enable this off-line simulation and analysis. The main conclusions are as follows： the Noah LSM performed well on the northern Tibetan Plateau. The simulated net radiation, upward longwave radiation, and upward shortwave radiation demonstrated the same remarkable annual and seasonal variation as the observed data, especially the upward longwave radiation. The simulated soil temperatures were acceptably close to the observed temperatures, especially in the shallow soil layers. The simulated freezing and melting processes were shown to start from the surface soil layer and spread down to the deep soil layers, but they took longer than the observed processes. However, Noah LSM did not adequately simulate the soil moisture. Therefore, additional high-quality, long-term observations of land surface-atmosphere processes over the Tibetan Plateau will be a key factor in proper adiustments of the model parameters in the future.

Chinese Customers' WTP for Legal Digital Music Downloading

This study is to examine the effects of some significant factors on consumers' willingness to pay( WTP) for digital music via the moderating variables of music affinity and the deterrence effect of the legislation. Based on 517 Chinese respondents with access to digital music,using the multiple liner regression model,this study indicates that free ideology,perceived benefits of free downloading,perceived benefits of paid downloading,subjective norm,habit strength have direct influence on WTP,and music affinity and the deterrence effect of the legislation have moderating effects. This study contributes theoretically to research on Chinese consumers' WTP for digital music and offers practical recommendations for the digital music charging system setup.

A word level segmentation for off-line Arabic characters

Segmentation of cursive text has been one of the major problems in Arabic writing. The problem is the shape of the letter which is context sensitive, depending on it’s location within a word. Many text recognition systems recognize text imagery at the character level and assemble words from the recognized characters. Unfortunately this approach does not work with Arabic text. In this paper we describe a new approach to segment Arabic text imagery at a word level, without analyzing individual characters. This approach avoids the problem of individual characters segmentation, and can overcome local errors in character recognition.

Off-line simulation of robot welding of radar pedestal

A study of the interference simulation based on robot welding of the radar pedestal was carried out by using the KUKA Sim Pro simulation software and off-line program technology. Compared with the actual robot welding process, it was found that the trajectory of the simulated robot welding process in line with that recorded in the actual welding process, and the actual limit and interference appeared at the same place as the simulation process. There was no interference phenomenon on the outside weld-seam; on the internal weld-seam, especially on the weld-joint of support plate connected to the cylinder, a phenomenon of interference appeared. It was helpful to use the simulation method to guide the actual robot welding so as to protect robot from impacting and reduce the weld defects.

Study on path planning and compensation of off-line programming for thick walled curve welding

Thick walled curve welding are usually joined by multi-layer and multi-pass welding, which quality and efficiency could be improved by off-line programming of robot welding. However, the precision of off-line programming welding path was decreased due to the deviation between the off-line planned welding path and the actual welding path. A path planning algorithm and a path compensation algorithm of multi-layer and multi-pass curve welding seam for off-line programming of robot welding are developed in this paper. Experimental results show that the robot off-line programming improves the welding efftcieney and precision for thick walled curve welding seam.

Influences of digital resource acquisition on scientific research behaviors——The statistical analysis on the full-text downloading quantity and cited times

With the emergence and further development of the digital library, the approaches of information acquisition correspondingly change a lot. This paper makes a statistical analysis on the journal downloading and citation behaviors under the digital environment conceived by the National Science Library(NSL), Chinese Academy of Sciences(CAS). It can be seen that the development of digital resources has influenced scientific research behaviors. For example, the large quantity of full-text downloading will maintain; the trend of journal downloading behaviors is basically same as the journal citation behavior; journals with large quantity of full-text downloading also boast the high cited times, and vice versa. Furthermore, authors make a linear regression analysis, with the journal downloading amount as the independent variable and journal cited times as dependent variable. Then they also prove the positive correlation between the journal downloading and citation behaviors by means of Pearson's correlation coefficient formula.

SPECTRAL TECHNIQUES FOR OFF-LINE TESTING AND DIAGNOSIS OF COMPUTER SYSTEMS

In this paper we present some of our recent results on applications of spectral techniques over finite fields to the problems of testing and diagnosis of computer systems.

CDMA2000下载业务系统中Download协议监测技术的研究与实现

增值业务的产生,丰富了通信网络,同时也增加了网络负荷。为保证通信质量,对增值业务关键接口进行监测的研究显得尤为重要。以CDMA2000网络作为承载网络,以增值业务网络中的下载业务系统作为切入点,对该系统与WAP网关相连接口下的Download协议进行监测研究;通过构造合理的哈希函数优化了CDR(calling detail record)合成处理速度。将此方法推广至增值业务中的其他关键接口,通过现网数据测试,运行效果良好。

基于浏览器扩展的Drive-by Download防御方法

基于Web的病毒感染及扩散方法,目前成为了互联网中病毒传播的主要方式。Drive-by Download攻击是其中一种非常常见的攻击方法。文中用浏览器扩展来监控用户下载文件的活动,从而建立相应的白表。同时在内核空间安装钩子,用于阻止非用户下载文件的执行,从而有效地防御Drive-by Download攻击。文中实现了一个在Windows操作系统上,基于Firefox扩展的原型系统:DPrevent(Drive-by Download Prevent)。实验表明,该系统的误报和漏报率都为零。同时因为它本身不需要知道具体的攻击方法,因此还可以有效地防御zero-day攻击。该系统的性能开销几乎为零,优于目前这方面的各种动态防御技术。

Cluster-Based Content Download and Forwarding Scheme for Highway VANETs

The recent advances in wireless communication technology enable high-speed vehicles to download data from roadside units(RSUs). However, the data download volume of individual vehicle is rather restricted due to high mobility and limited transmission range of vehicles, bringing users poor performance. To address this issue, we exploit the combination of both clustering and carry-and-forward schemes in this paper. Our scheme coordinates the cooperation of multiple infrastructures, cluster formation in the same direction and data forwarding of reverse vehicles to facilitate the target vehicle to download large-size content in dark areas. The process of data dissemination and achievable data download volume are then derived and analyzed theoretically. Finally, we conduct extensive simulations to verify the performance of the proposed scheme. Results show significant benefits of the proposed scheme in terms of increasing data download volume and throughput.

Adaptive progressive download based on the MPEG-4 file format

In this paper we describe how progressive download and adaptive streaming can be combined into a simple and efficient streaming framework. Based on the MPEG-4 file format (MP4) we use HTTP for transport and argue that these two components are sufficient for specifying an open streaming architecture. The client selects appropriate chunks from the MP4 file to be transferred based on (1) the header information (i.e. the 'moov' box) in the first part of the file and (2) his observation of network throughput. The framework is completely client driven which allows for better server scalability and reduces signalling overhead. We discuss architecture and implementation issues such as complexity, interoperability and scalability and compare to 3GPP PSS Re1-6 adaptive streaming when appropriate. Measurements from a simple MP4/HTTP streaming client are presented showing that appropriate chunks are selected such that increased reliability is achieved.

A Data Download Method from RSUs Using Fog Computing in Connected Vehicles

Communication is important for providing intelligent services in connected vehicles.Vehicles must be able to communicate with different places and exchange information while driving.For service operation,connected vehicles frequently attempt to download large amounts of data.They can request data downloading to a road side unit(RSU),which provides infrastructure for connected vehicles.The RSU is a data bottleneck in a transportation system because data traffic is concentrated on the RSU.Therefore,it is not appropriate for a connected vehicle to always attempt a high speed download from the RSU.If the mobile network between a connected vehicle and an RSU has poor connection quality,the efficiency and speed of the data download from the RSU is decreased.This problem affects the quality of the user experience.Therefore,it is important for a connected vehicle to connect to an RSU with consideration of the network conditions in order to try to maximize download speed.The proposed method maximizes download speed from an RSU using a machine learning algorithm.To collect and learn from network data,fog computing is used.A fog server is integrated with the RSU to perform computing.If the algorithm recognizes that conditions are not good for mass data download,it will not attempt to download at high speed.Thus,the proposed method can improve the efficiency of high speed downloads.This conclusion was validated using extensive computer simulations.

基于CAN通信实现MBD代码下载的DSP Bootloader开发

为了实现DSP嵌入式系统在实际应用中便捷下载MBD(model-based design)代码的需求,文章设计了一种基于CAN通信实现MBD代码下载的Bootloader方案。以TMS320F28335为例,通过对MBD代码的结构进行分析,设计了Boot程序与MBD程序的内存划分方案,确保程序下载的有效性和稳定性;开发了相应的Boot程序和上位机程序,详细介绍了Bootloader的实现流程,并对关键步骤函数进行了分析与解释,利用CAN通信实现了程序的下载。实验结果表明,该方法稳定可靠且具有实用性,为DSP嵌入式系统在实际应用中的MBD代码下载提供了一种可行且高效的解决方案。