Percutaneous electrical nerve stimulation of an injured nerve can promote and accelerate peripheral nerve regeneration and improve function.When performing acupuncture and moxibustion,locating the injured nerve using ...Percutaneous electrical nerve stimulation of an injured nerve can promote and accelerate peripheral nerve regeneration and improve function.When performing acupuncture and moxibustion,locating the injured nerve using ultrasound before percutaneous nerve stimulation can help prevent further injury to an already injured nerve.However,stimulation parameters have not been standardized.In this study,we constructed a multi-layer human forearm model using finite element modeling.Taking current density and activated function as optimization indicators,the optimal percutaneous nerve stimulation parameters were established.The optimal parameters were parallel placement located 3 cm apart with the injury site at the midpoint between the needles.To validate the efficacy of this regimen,we performed a randomized controlled trial in 23 patients with median nerve transection who underwent neurorrhaphy.Patients who received conventional rehabilitation combined with percutaneous electrical nerve stimulation experienced greater improvement in sensory function,motor function,and grip strength than those who received conventional rehabilitation combined with transcutaneous electrical nerve stimulation.These findings suggest that the percutaneous electrical nerve stimulation regimen established in this study can improve global median nerve function in patients with median nerve transection.展开更多
This paper uses a grouping-adjusting procedure to the data from a median linear regression model, and estimtes the regression coefficients by the method of weighted least squares. This method simplifies computation an...This paper uses a grouping-adjusting procedure to the data from a median linear regression model, and estimtes the regression coefficients by the method of weighted least squares. This method simplifies computation and in the meantime, preserves the same asymptotic normal distribution for the estimator, as in the ordinary minimum L_1-norm estimates.展开更多
Recently, the inverse connected p-median problem on block graphs G(V,E,w) under various cost functions, say rectilinear norm, Chebyshev norm, and bottleneck Hamming distance. Their contributions include finding a nece...Recently, the inverse connected p-median problem on block graphs G(V,E,w) under various cost functions, say rectilinear norm, Chebyshev norm, and bottleneck Hamming distance. Their contributions include finding a necessary and sufficient condition for the connected p-median problem on block graphs, developing algorithms and showing that these problems can be solved in O(n log n) time, where n is the number of vertices in the underlying block graph. Using similar technique, we show that some results are incorrect by a counter-example. Then we redefine some notations, reprove Theorem 1 and redescribe Theorem 2, Theorem 3 and Theorem 4.展开更多
The microscopic global nucleon–nucleus optical model potential(OMP)proposed by Whitehead,Lim,and Holt,the WLH potential(Whitehead et al.,Phys Rev Lett 127:182502,2021),which was constructed in the framework of many-b...The microscopic global nucleon–nucleus optical model potential(OMP)proposed by Whitehead,Lim,and Holt,the WLH potential(Whitehead et al.,Phys Rev Lett 127:182502,2021),which was constructed in the framework of many-body per-turbation theory with state-of-the-art nuclear interactions from chiral effective field theory(EFT),was tested with(p,d)transfer reactions calculated using adiabatic wave approximation.The target nuclei included both stable and unstable nuclei,and the incident energies reached 200 MeV.The results were compared with experimental data and predictions using the phenomenological global optical potential of Koning and Delaroche,the KD02 potential.Overall,we found that the micro-scopic WLH potential described the(p,d)reaction angular distributions similarly to the phenomenological KD02 potential;however,the former was slightly better than the latter for radioactive targets.On average,the obtained spectroscopic factors(SFs)using both microscopic and phenomenological potentials were similar when the incident energies were below approxi-mately 120 MeV.However,their difference tended to increase at higher incident energies,which was particularly apparent for the doubly magic target nucleus 40Ca.展开更多
In this paper, we consider median unbiased estimation of bivariate predictive regression models with non-normal, heavy-tailed or heteroscedastic errors. We construct confidence intervals and median unbiased estimator ...In this paper, we consider median unbiased estimation of bivariate predictive regression models with non-normal, heavy-tailed or heteroscedastic errors. We construct confidence intervals and median unbiased estimator for the parameter of interest. We show that the proposed estimator has better predictive potential than the usual least squares estimator via simulation. An empirical application to finance is given. And a possible extension of the estimation procedure to cointegration models is also described.展开更多
为倡导绿色出行理念,解决以往研究在处理重复观测数据时容易忽视的潜在相关性和个体异质性问题,针对如何利用智能手机APP提供的多模式出行信息引导小汽车出行者转向停车换乘(Park-and-Ride,P+R)模式进行了探究,同时引入广义线性混合模型...为倡导绿色出行理念,解决以往研究在处理重复观测数据时容易忽视的潜在相关性和个体异质性问题,针对如何利用智能手机APP提供的多模式出行信息引导小汽车出行者转向停车换乘(Park-and-Ride,P+R)模式进行了探究,同时引入广义线性混合模型(Generalized Linear Mixed Model,GLMM)分析了多模式出行信息对小汽车出行者转向P+R意向的影响。首先,基于上海市路网设计意向调查问卷,整合了自驾和P+R两种出行方式的道路拥堵程度、出行时间、停车费用及地铁车厢座位情况等信息,并运用全因子设计法构建了24种不同信息水平组合的假设情景。然后,通过智能手机APP界面示意图向小汽车出行者展示这些多模式出行信息,并收集其转向P+R的意向数据。最后,运用GLMM方法处理同一个体重复决策数据中潜在的相关性和捕捉个体间的异质性。结果显示,GLMM的应用不仅解决了同一个体重复决策间的相关性,还揭示了不同个体对道路拥堵程度和地铁车厢座位情况的差异化关注;智能手机APP整合的多模式出行信息显著提升了小汽车出行者转向P+R的意愿,且这一转变占比达29.2%;高收入、长驾龄以及对P+R政策不了解的出行者转向P+R的意愿较低。研究表明,通过智能手机APP整合自驾和P+R的多模式出行信息能显著增强P+R方式的吸引力,可为提升P+R的普及率提供新思路,有效促进小汽车出行者向绿色出行方式的转变。展开更多
Sites with varying geometric features were analyzed to develop the 85 th percentile speed prediction models for car and sports utility vehicle(SUV) at 50 m prior to the point of curvature(PC), PC, midpoint of a curve(...Sites with varying geometric features were analyzed to develop the 85 th percentile speed prediction models for car and sports utility vehicle(SUV) at 50 m prior to the point of curvature(PC), PC, midpoint of a curve(MC), point of tangent(PT) and 50 m beyond PT on four-lane median divided rural highways. The car and SUV speed data were combined in the analysis as they were found to be normally distributed and not significantly different. Independent parameters representing geometric features and speed at the preceding section were logically selected in stepwise regression analyses to develop the models. Speeds at various locations were found to be dependent on some combinations of curve length, curvature and speed in the immediately preceding section of the highway. Curve length had a significant effect on the speed at locations 50 m prior to PC, PC and MC. The effect of curvature on speed was observed only at MC. The curve geometry did not have a significant effect on speed from PT onwards. The speed at 50 m prior to PC and curvature is the most significant parameter that affects the speed at PC and MC, respectively. Before entering a horizontal curve, drivers possibly perceive the curve based on its length. Longer curve encourages drivers to maintain higher speed in the preceding tangent section. Further, drivers start experiencing the effect of curvature only after entering the curve and adjust speed accordingly. Practitioners can use these findings in designing consistent horizontal curve for vehicle speed harmony.展开更多
基金supported by the National Natural Science Foundation of China,No.81801787(to XZS)China Postdoctoral Science Foundation,No.2018M640238(to XZS)the Natural Science Foundation of Tianjin,No.20JCQNJC01690(to XLC)。
文摘Percutaneous electrical nerve stimulation of an injured nerve can promote and accelerate peripheral nerve regeneration and improve function.When performing acupuncture and moxibustion,locating the injured nerve using ultrasound before percutaneous nerve stimulation can help prevent further injury to an already injured nerve.However,stimulation parameters have not been standardized.In this study,we constructed a multi-layer human forearm model using finite element modeling.Taking current density and activated function as optimization indicators,the optimal percutaneous nerve stimulation parameters were established.The optimal parameters were parallel placement located 3 cm apart with the injury site at the midpoint between the needles.To validate the efficacy of this regimen,we performed a randomized controlled trial in 23 patients with median nerve transection who underwent neurorrhaphy.Patients who received conventional rehabilitation combined with percutaneous electrical nerve stimulation experienced greater improvement in sensory function,motor function,and grip strength than those who received conventional rehabilitation combined with transcutaneous electrical nerve stimulation.These findings suggest that the percutaneous electrical nerve stimulation regimen established in this study can improve global median nerve function in patients with median nerve transection.
基金Research supported By AFOSC, USA, under Contract F49620-85-0008oy NNSFC of China.
文摘This paper uses a grouping-adjusting procedure to the data from a median linear regression model, and estimtes the regression coefficients by the method of weighted least squares. This method simplifies computation and in the meantime, preserves the same asymptotic normal distribution for the estimator, as in the ordinary minimum L_1-norm estimates.
文摘Recently, the inverse connected p-median problem on block graphs G(V,E,w) under various cost functions, say rectilinear norm, Chebyshev norm, and bottleneck Hamming distance. Their contributions include finding a necessary and sufficient condition for the connected p-median problem on block graphs, developing algorithms and showing that these problems can be solved in O(n log n) time, where n is the number of vertices in the underlying block graph. Using similar technique, we show that some results are incorrect by a counter-example. Then we redefine some notations, reprove Theorem 1 and redescribe Theorem 2, Theorem 3 and Theorem 4.
基金Supported by National Natural Science Foundation of China(Nos.U2067205 and 12205098)National Key Laboratory of Computational Physics(HX02021-35).
文摘The microscopic global nucleon–nucleus optical model potential(OMP)proposed by Whitehead,Lim,and Holt,the WLH potential(Whitehead et al.,Phys Rev Lett 127:182502,2021),which was constructed in the framework of many-body per-turbation theory with state-of-the-art nuclear interactions from chiral effective field theory(EFT),was tested with(p,d)transfer reactions calculated using adiabatic wave approximation.The target nuclei included both stable and unstable nuclei,and the incident energies reached 200 MeV.The results were compared with experimental data and predictions using the phenomenological global optical potential of Koning and Delaroche,the KD02 potential.Overall,we found that the micro-scopic WLH potential described the(p,d)reaction angular distributions similarly to the phenomenological KD02 potential;however,the former was slightly better than the latter for radioactive targets.On average,the obtained spectroscopic factors(SFs)using both microscopic and phenomenological potentials were similar when the incident energies were below approxi-mately 120 MeV.However,their difference tended to increase at higher incident energies,which was particularly apparent for the doubly magic target nucleus 40Ca.
基金The NNSF(10571073)of china,and 985 project of Jilin University.
文摘In this paper, we consider median unbiased estimation of bivariate predictive regression models with non-normal, heavy-tailed or heteroscedastic errors. We construct confidence intervals and median unbiased estimator for the parameter of interest. We show that the proposed estimator has better predictive potential than the usual least squares estimator via simulation. An empirical application to finance is given. And a possible extension of the estimation procedure to cointegration models is also described.
文摘为倡导绿色出行理念,解决以往研究在处理重复观测数据时容易忽视的潜在相关性和个体异质性问题,针对如何利用智能手机APP提供的多模式出行信息引导小汽车出行者转向停车换乘(Park-and-Ride,P+R)模式进行了探究,同时引入广义线性混合模型(Generalized Linear Mixed Model,GLMM)分析了多模式出行信息对小汽车出行者转向P+R意向的影响。首先,基于上海市路网设计意向调查问卷,整合了自驾和P+R两种出行方式的道路拥堵程度、出行时间、停车费用及地铁车厢座位情况等信息,并运用全因子设计法构建了24种不同信息水平组合的假设情景。然后,通过智能手机APP界面示意图向小汽车出行者展示这些多模式出行信息,并收集其转向P+R的意向数据。最后,运用GLMM方法处理同一个体重复决策数据中潜在的相关性和捕捉个体间的异质性。结果显示,GLMM的应用不仅解决了同一个体重复决策间的相关性,还揭示了不同个体对道路拥堵程度和地铁车厢座位情况的差异化关注;智能手机APP整合的多模式出行信息显著提升了小汽车出行者转向P+R的意愿,且这一转变占比达29.2%;高收入、长驾龄以及对P+R政策不了解的出行者转向P+R的意愿较低。研究表明,通过智能手机APP整合自驾和P+R的多模式出行信息能显著增强P+R方式的吸引力,可为提升P+R的普及率提供新思路,有效促进小汽车出行者向绿色出行方式的转变。
基金Indian Institute of Technology Bombay for providing funding (Project code:13IRCCSG001)
文摘Sites with varying geometric features were analyzed to develop the 85 th percentile speed prediction models for car and sports utility vehicle(SUV) at 50 m prior to the point of curvature(PC), PC, midpoint of a curve(MC), point of tangent(PT) and 50 m beyond PT on four-lane median divided rural highways. The car and SUV speed data were combined in the analysis as they were found to be normally distributed and not significantly different. Independent parameters representing geometric features and speed at the preceding section were logically selected in stepwise regression analyses to develop the models. Speeds at various locations were found to be dependent on some combinations of curve length, curvature and speed in the immediately preceding section of the highway. Curve length had a significant effect on the speed at locations 50 m prior to PC, PC and MC. The effect of curvature on speed was observed only at MC. The curve geometry did not have a significant effect on speed from PT onwards. The speed at 50 m prior to PC and curvature is the most significant parameter that affects the speed at PC and MC, respectively. Before entering a horizontal curve, drivers possibly perceive the curve based on its length. Longer curve encourages drivers to maintain higher speed in the preceding tangent section. Further, drivers start experiencing the effect of curvature only after entering the curve and adjust speed accordingly. Practitioners can use these findings in designing consistent horizontal curve for vehicle speed harmony.
