Alternative Methods of Regular and Singular Perturbation Problems

Making exact approximations to solve equations distinguishes applied mathematicians from pure mathematicians, physicists, and engineers. Perturbation problems, both regular and singular, are pervasive in diverse fields of applied mathematics and engineering. This research paper provides a comprehensive overview of algebraic methods for solving perturbation problems, featuring a comparative analysis of their strengths and limitations. Serving as a valuable resource for researchers and practitioners, it offers insights and guidance for tackling perturbation problems in various disciplines, facilitating the advancement of applied mathematics and engineering.

A proteomic landscape of pharmacologic perturbations for functional relevance

Pharmacological perturbation studies based on protein-level signatures are fundamental for drug discovery. In the present study, we used a mass spectrometry (MS)-based proteomic platform to profile the whole proteome of the breast cancer MCF7 cell line under stress induced by 78 bioactive compounds. The integrated analysis of perturbed signal abundance revealed the connectivity between phenotypic behaviors and molecular features in cancer cells. Our data showed functional relevance in exploring the novel pharmacological activity of phenolic xanthohumol, as well as the noncanonical targets of clinically approved tamoxifen, lovastatin, and their derivatives. Furthermore, the rational design of synergistic inhibition using a combination of histone methyltransferase and topoisomerase was identified based on their complementary drug fingerprints. This study provides rich resources for the proteomic landscape of drug responses for precision therapeutic medicine.

A novel algorithm for evaluating cement azimuthal density based on perturbation theory in horizontal well

Cement density monitoring plays a vital role in evaluating the quality of cementing projects,which is of great significance to the development of oil and gas.However,the presence of inhomogeneous cement distribution and casing eccentricity in horizontal wells often complicates the accurate evaluation of cement azimuthal density.In this regard,this paper proposes an algorithm to calculate the cement azimuthal density in horizontal wells using a multi-detector gamma-ray detection system.The spatial dynamic response functions are simulated to obtain the influence of cement density on gamma-ray counts by the perturbation theory,and the contribution of cement density in six sectors to the gamma-ray recorded by different detectors is obtained by integrating the spatial dynamic response functions.Combined with the relationship between gamma-ray counts and cement density,a multi-parameter calculation equation system is established,and the regularized Newton iteration method is employed to invert casing eccentricity and cement azimuthal density.This approach ensures the stability of the inversion process while simultaneously achieving an accuracy of 0.05 g/cm^(3) for the cement azimuthal density.This accuracy level is ten times higher compared to density accuracy calculated using calibration equations.Overall,this algorithm enhances the accuracy of cement azimuthal density evaluation,provides valuable technical support for the monitoring of cement azimuthal density in the oil and gas industry.

Investigation on the roles of equilibrium toroidal rotation during edge-localized mode mitigated by resonant magnetic perturbations

The effects of equilibrium toroidal rotation during edge-localized mode(ELM)mitigated by resonant magnetic perturbation(RMP)are studied with the experimental equilibria of the EAST tokamak based on the four-field model in the BOUT++code.As the two main parameters to determine the toroidal rotation profiles,the rotation shear and magnitudes were separately scanned to investigate their roles in the impact of RMPs on peeling-ballooning(P-B)modes.On one hand,the results show that strong toroidal rotation shear is favorable for the enhancement of the self-generated E×B shearing rate<ω_(E×B)>with RMPs,leading to significant ELM mitigation with RMP in the stronger toroidal rotation shear region.On the other hand,toroidal rotation magnitudes may affect ELM mitigation by changing the penetration of the RMPs,more precisely the resonant components.RMPs can lead to a reduction in the pedestal energy loss by enhancing the multimode coupling in the turbulence transport phase.The shielding effects on RMPs increase with the toroidal rotation magnitude,leading to the enhancement of the multimode coupling with RMPs to be significantly weakened.Hence,the reduction in pedestal energy loss by RMPs decreased with the rotation magnitude.In brief,the results show that toroidal rotation plays a dual role in ELM mitigation with RMP by changing the shielding effects of plasma by rotation magnitude and affecting<ω_(E×B)>by rotation shear.In the high toroidal rotation region,toroidal rotation shear is usually strong and hence plays a dominant role in the influence of RMP on P-B modes,whereas in the low rotation region,toroidal rotation shear is weak and has negligible impact on P-B modes,and the rotation magnitude plays a dominant role in the influence of RMPs on the P-B modes by changing the field penetration.Therefore,the dual role of toroidal rotation leads to stronger ELM mitigation with RMP,which may be achieved both in the low toroidal rotation region and the relatively high rotation region that has strong rotational shear.

An Initial Perturbation Method for the Multiscale Singular Vector in Global Ensemble Prediction

Ensemble prediction is widely used to represent the uncertainty of single deterministic Numerical Weather Prediction(NWP) caused by errors in initial conditions(ICs). The traditional Singular Vector(SV) initial perturbation method tends only to capture synoptic scale initial uncertainty rather than mesoscale uncertainty in global ensemble prediction. To address this issue, a multiscale SV initial perturbation method based on the China Meteorological Administration Global Ensemble Prediction System(CMA-GEPS) is proposed to quantify multiscale initial uncertainty. The multiscale SV initial perturbation approach entails calculating multiscale SVs at different resolutions with multiple linearized physical processes to capture fast-growing perturbations from mesoscale to synoptic scale in target areas and combining these SVs by using a Gaussian sampling method with amplitude coefficients to generate initial perturbations. Following that, the energy norm,energy spectrum, and structure of multiscale SVs and their impact on GEPS are analyzed based on a batch experiment in different seasons. The results show that the multiscale SV initial perturbations can possess more energy and capture more mesoscale uncertainties than the traditional single-SV method. Meanwhile, multiscale SV initial perturbations can reflect the strongest dynamical instability in target areas. Their performances in global ensemble prediction when compared to single-scale SVs are shown to(i) improve the relationship between the ensemble spread and the root-mean-square error and(ii) provide a better probability forecast skill for atmospheric circulation during the late forecast period and for short-to medium-range precipitation. This study provides scientific evidence and application foundations for the design and development of a multiscale SV initial perturbation method for the GEPS.

A generalization of Banach's lemma and its applications to perturbations of bounded linear operators

Let X be a Banach space and let P:X→X be a bounded linear operator.Using an algebraic inequality on the spectrum of P,we give a new sufficient condition that guarantees the existence of(I-P)^(-1) as a bounded linear operator on X,and a bound on its spectral radius is also obtained.This generalizes the classic Banach lemma.We apply the result to the perturbation analysis of general bounded linear operators on X with commutative perturbations.

Generalized nth-Order Perturbation Method Based on Loop Subdivision Surface Boundary Element Method for Three-Dimensional Broadband Structural Acoustic Uncertainty Analysis

In this paper,a generalized nth-order perturbation method based on the isogeometric boundary element method is proposed for the uncertainty analysis of broadband structural acoustic scattering problems.The Burton-Miller method is employed to solve the problem of non-unique solutions that may be encountered in the external acoustic field,and the nth-order discretization formulation of the boundary integral equation is derived.In addition,the computation of loop subdivision surfaces and the subdivision rules are introduced.In order to confirm the effectiveness of the algorithm,the computed results are contrasted and analyzed with the results under Monte Carlo simulations(MCs)through several numerical examples.

Growth of ablative Rayleigh-Taylor instability induced by time-varying heat-flux perturbation

The evolution of ablative Rayleigh–Taylor instability(ARTI)induced by single-mode stationary and time-varying perturbations in heat flux is studied numerically in two dimensions.Compared with the stationary case,time-varying heat-flux perturbation mitigates ARTI growth because of the enhanced thermal smoothing induced by the wave-like traveling heat flux.A resonance is found to form when the phase velocity of the heat-flux perturbation matches the average sound speed in the ablation region.In the resonant regime,the coherent density and temperature fluctuations enhance the electron thermal conduction in the ablation region and lead to larger ablation pressure and effective acceleration,which consequently yield higher linear growth rate and saturated bubble velocity.The enhanced effective acceleration offers increased implosion velocity but can also compromise the integrity of inertial confinement fusion shells by causing faster ARTI growth.

Comparison of transport coefficients before and after density pump-out induced by resonant magnetic perturbation using a BOUT++ six-field model on the EAST tokamak

Many experiments have demonstrated that resonant magnetic perturbation(RMP) can affect the turbulent transport at the edge of the tokamak. Through the Experimental Advanced Superconducting Tokamak(EAST) density modulation experiment, the particle transport coefficients were calculated using the experimental data, and the result shows that the particle transport coefficients increase with RMP. In this study, the six-field two-fluid model in BOUT++ is used to simulate the transport before and after density pump-out induced by RMP,respectively referred as the case without RMP and the case with RMP. In the linear simulations,the instabilities generally decreases for cases with RMP. In the nonlinear simulation, ELM only appears in the case without RMP. Additionally, the particle transport coefficient was analyzed,and the result shows that the particle transport coefficient becomes larger for the case with RMP,which is consistent with the experimental conclusion. Moreover, its magnitude is comparable to the results calculated from experimental data.

Volcanically Driven Terrestrial Environmental Perturbations during the Carnian Pluvial Episode in the Eastern Tethys

The Carnian Pluvial Episode(CPE)fingerprints global environmental perturbations and biological extinction on land and oceans and is potentially linked to the Wrangellia Large Igneous Province(LIP).However,the correlation between terrestrial environmental changes and Wrangellia volcanism in the Ordos Basin during the CPE remains poorly understood.Records of negative carbon isotopic excursions(NCIEs),mercury(Hg),Hg/TOC,and Hg enrichment factor(HgEF)from oil shales in a large-scale terrestrial Ordos Basin in the Eastern Tethys were correlated with marine and other terrestrial successions.The three significant NCIEs in the study section were consistently correlated with those in the CPE successions of Europe,the UK,and South and North China.The U-Pb geochronology indicates a Ladinian-Carnian age for the Chang 7 Member.A comprehensive overview of the geochronology,NCIE correlation,and previous bio-and chronostratigraphic frameworks shows that the Ladinian-Carnian boundary is located in the lower part of Chang 7 in the Yishicun section.HgEF may be a more reliable proxy for tracing volcanic eruptions than the Hg/TOC ratio because the accumulation rates of TOC content largely vary in terrestrial and marine successions.The records of Hg,Hg/TOC,HgEF,and NCIEs in the Ordos Basin aligned with Carnian successions worldwide and were marked by similar anomalies,indicating a global response to the Wrangellia LIP during the CPE.Anoxia,a warm-humid climate,enhancement of detrital input,and NCIEs are synchronous with the CPE interval in the Ordos Basin,which suggests that the CPE combined with the regional Qinling Orogeny should dominate the enhanced rate of terrigenous input and paleoenvironmental evolution in the Ordos Basin.

Growth and Interactions of Multi-Source Perturbations in Convection-Allowing Ensemble Forecasts

This study investigated the growth of forecast errors stemming from initial conditions(ICs),lateral boundary conditions(LBCs),and model(MO)perturbations,as well as their interactions,by conducting seven 36 h convectionallowing ensemble forecast(CAEF)experiments.Two cases,one with strong-forcing(SF)and the other with weak-forcing(WF),occurred over the Yangtze-Huai River basin(YHRB)in East China,were selected to examine the sources of uncertainties associated with perturbation growth under varying forcing backgrounds and the influence of these backgrounds on growth.The perturbations exhibited distinct characteristics in terms of temporal evolution,spatial propagation,and vertical distribution under different forcing backgrounds,indicating a dependence between perturbation growth and forcing background.A comparison of the perturbation growth in different precipitation areas revealed that IC and LBC perturbations were significantly influenced by the location of precipitation in the SF case,while MO perturbations were more responsive to convection triggering and dominated in the WF case.The vertical distribution of perturbations showed that the sources of uncertainties and the performance of perturbations varied between SF and WF cases,with LBC perturbations displaying notable case dependence.Furthermore,the interactions between perturbations were considered by exploring the added values of different source perturbations.For the SF case,the added values of IC,LBC,and MO perturbations were reflected in different forecast periods and different source uncertainties,suggesting that the combination of multi-source perturbations can yield positive interactions.In the WF case,MO perturbations provided a more accurate estimation of uncertainties downstream of the Dabie Mountain and need to be prioritized in the research on perturbation development.

Inducing Unstable Grassland Equilibrium States Due to Nonlinear Optimal Patterns of Initial and Parameter Perturbations:Theoretical Models

Due to uncertainties in initial conditions and parameters, the stability and uncertainty of grassland ecosystem simulations using ecosystem models are issues of concern. Our objective is to determine the types and patterns of initial and parameter perturbations that yield the greatest instability and uncertainty in simulated grassland ecosystems using theoretical models. We used a nonlinear optimization approach, i.e., a conditional nonlinear optimal perturbation related to initial and parameter perturbations （CNOP） approach, in our work. Numerical results indicated that the CNOP showed a special and nonlinear optimal pattern when the initial state variables and multiple parameters were considered simultaneously. A visibly different complex optimal pattern characterizing the CNOPs was obtained by choosing different combinations of initial state variables and multiple parameters in different physical processes. We propose that the grassland modeled ecosystem caused by the CNOP-type perturbation is unstable and exhibits two aspects： abrupt change and the time needed for the abrupt change from a grassland equilibrium state to a desert equilibrium state when the initial state variables and multiple parameters are considered simultaneously. We compared these findings with results affected by the CNOPs obtained by considering only uncertainties in initial state variables and in a single parameter. The numerical results imply that the nonlinear optimal pattern of initial perturbations and parameter perturbations, especially for more parameters or when special parameters are involved, plays a key role in determining stabilities and uncertainties associated with a simulated or predicted grassland ecosystem.

Frequency characteristics and far-field effect of gravity perturbation before earthquake

We used high-pass filtering and the Fourier transform to analyze tidal gravity data prior to five earthquakes from four superconducting gravity stations around the world. A stable gravitational perturbation signal is received within a few days before the earthquakes. The gravitational perturbation signal before the Wenchuan earthquake on May 12, 2008 has main frequency of 0.1–0.3 Hz, and the other four have frequency bands of 0.12-0.17 Hz and 0.06-0.085 Hz. For earthquakes in continental and oceanic plate fault zones, gravity anomalies often appear on the superconducting gravimeters away from the epicenter, whereas the stations near the epicenter record small or no anomalies. The results suggest that this kind of gravitational perturbation signals correlate with earthquake occurrence, making them potentially useful earthquake predictors. The far-field effect of the gravitational perturbation signals may reveal the interaction mechanisms of the Earth’s tectonic plates. However, owing to the uneven distribution of gravity tide stations, the results need to be further confirmed in the future.

Singular perturbation for the weakly nonlinear reaction diffusion equation with boundary perturbation

In this paper, a class of nonlinear singularly perturbed initial boundary value problems for reaction diffusion equations with boundary perturbation are considered under suitable conditions. Firstly, by dint of the regular perturbation method, the outer solution of the original problem is obtained. Secondly, by using the stretched variable and the expansion theory of power series the initial layer of the solution is constructed. And then, by using the theory of differential inequalities, the asymptotic behavior of the solution for the initial boundary value problems is studied. Finally, using some relational inequalities the existence and uniqueness of solution for the original problem and the uniformly valid asymptotic estimation are discussed.

Impacts of New Implementing Strategies for Surface and Model Physics Perturbations in TREPS on Forecasts of Landfalling Tropical Cyclones

To improve the ensemble prediction system of the tropical regional atmosphere model for the South China Sea(TREPS) in predicting landfalling tropical cyclones(TCs), the impacts of three new implementing strategies for surface and model physics perturbations in TREPS were evaluated for 19 TCs making landfall in China during 2014–16. For sea surface temperature(SST) perturbations, spatially uncorrelated random perturbations were replaced with spatially correlated ones. The multiplier f, which is used to form perturbed tendency in the Stochastically Perturbed Parameterization Tendency(SPPT) scheme, was inflated in regions with evident convective activity(f-inflated SPPT). Lastly, the Stochastically Perturbed Parameterization(SPP) scheme with 14 perturbed parameters selected from the planetary boundary layer, surface layer, microphysics, and cumulus convection parameterizations was added. Overall, all these methods improved forecasts more significantly for non-intensifying than intensifying TCs. Compared with f-inflated SPPT,the spatially correlated SST perturbations generally showed comparable performance but were more(less) skillful for intensifying(non-intensifying) TCs. The advantages of the spatially correlated SST perturbations and f-inflated SPPT were mainly present in the deterministic guidance for both TC track and wind and in the probabilistic guidance for reliability of wind. For intensifying TCs, adding SPP led to mixed impacts with significant improvements in probability-matched mean of modest winds and in probabilistic forecasts of rainfall;while for non-intensifying TCs, adding SPP frequently led to positive impacts on the deterministic guidance for track, intensity, strong winds, and moderate rainfall and on the probabilistic guidance for wind and discrimination of rainfall.

Ground-state energy of beryllium atom with parameter perturbation method

We present a perturbation study of the ground-state energy of the beryllium atom by incorporating double parameters in the atom＇s Hamiltonian. The eigenvalue of the Hamiltonian is then solved with a double-fold perturbation scheme,where the spin-spin interaction of electrons from different shells of the atom is also considered. Calculations show that the obtained ground-state energy is in satisfactory agreement with experiment. It is found that the Coulomb repulsion of the inner-shell electrons enhances the effective nuclear charge seen by the outer-shell electrons, and the shielding effect of the outer-shell electrons to the nucleus is also notable compared with that of the inner-shell electrons.

Quasilinear singularly perturbed problem with boundary perturbation

A class of quasilinear singularly perturbed problems with boundary perturbation is considered. Under suitable conditions, using theory of differential inequalities we studied the asymptotic behavior of the solution for the boundary value problem.

PERTURBATION SOLUTION FOR COMPARTMENT MODEL OF VARIABLE EXTRACELLULAR VOLUME

The two compartment model with variable extracellular volume is presented and solved by using both perturbation and analytical method. The computation for both creatinine and urea show that the perturbation solution is not only simple but also accurate enough and is a good substitute for the more exact analytical solution.

A CLASS OF NONLINEAR SINGULARLY PERTURBED INITIAL BOUNDARY VALUE PROBLEMS FOR REACTION DIFFUSION EQUATIONS WITH BOUNDARY PERTURBATION

A class of nonlinear initial boundary value problems for reaction diffusion equations with boundary perturbation is considered. Under suitable conditions and using the theory of differential inequalities the asymptotic solution of the initial boundary value problems is studied.

Stability analysis for nonlinear multi-variable delay perturbation problems

This paper discusses the stability of theoretical solutions for nonlinear multi-variable delay perturbation problems (MVDPP) of the form x′(t)=f(x(t),x(t-τ 1(t)),...,x(t-τ m(t)),y(t),y(t-τ 1(t)),...,y(t-τ m(t))), and εy′(t)=g(x(t),x(t-τ 1(t)),...,x(t-τ m(t)),y(t),y(t-τ 1(t)),...,y(t-τ m(t))), where 0<ε1. A sufficient condition of stability for the systems is obtained. Additionally we prove the numerical solutions of the implicit Euler method are stable under this condition.