Unloading and successful treatment with bioresorbable stents during percutaneous coronary intervention:A case report

BACKGROUND With the development of percutaneous coronary intervention(PCI),the number of interventional procedures without implantation,such as bioresorbable stents(BRS)and drug-coated balloons,has increased annually.Metal drug-eluting stent unloading is one of the most common clinical complications.Comparatively,BRS detachment is more concealed and harmful,but has yet to be reported in clinical research.In this study,we report a case of BRS unloading and successful rescue.This is a case of a 59-year-old male with the following medical history:“Type 2 diabetes mellitus”for 2 years,maintained with metformin extended-release tablets,1 g PO BID;“hypertension”for 20 years,with long-term use of metoprolol sustained-release tablets,47.5 mg PO QD;“hyperlipidemia”for 20 years,without regular medication.He was admitted to the emergency department of our hospital due to intermittent chest pain lasting 18 hours,on February 20,2022 at 15:35.Electrocardiogram results showed sinus rhythm,ST-segment elevation in leads I and avL,and poor R-wave progression in leads V1–3.High-sensitivity troponin I level was 4.59 ng/mL,indicating an acute high lateral wall myocardial infarction.The patient’s family requested treatment with BRS,without implanta-tion.During PCI,the BRS became unloaded but was successfully rescued.The patient was followed up for 2 years;he had no episodes of angina pectoris and was in generally good condition.CONCLUSION We describe a case of a 59-year-old male experienced BRS unloading and successful rescue.By analyzing images,the causes of BRS unloading and the treatment plan are discussed to provide insights for BRS release operations.We discuss preventive measures for BRS unloading.

Impact of frailty on outcomes of elderly patients undergoing percutaneous coronary intervention: A systematic review and metaanalysis

BACKGROUND Frailty is a common condition in elderly patients who receive percutaneous coronary intervention(PCI).However,how frailty affects clinical outcomes in this group is unclear.AIM To assess the link between frailty and the outcomes,such as in-hospital complic-ations,post-procedural complications,and mortality,in elderly patients post-PCI.METHODS The PubMed/MEDLINE,EMBASE,Cochrane Library,and Web of Science databases were screened for publications up to August 2023.The primary outcomes assessed were in-hospital and all-cause mortality,major adverse cardiovascular events(MACEs),and major bleeding.The Newcastle-Ottawa Scale was used for quality assessment.RESULTS Twenty-one studies with 739693 elderly patients undergoing PCI were included.Frailty was consistently associated with adverse outcomes.Frail patients had significantly higher risks of in-hospital mortality[risk ratio:3.45,95%confidence interval(95%CI):1.90-6.25],all-cause mortality[hazard ratio(HR):2.08,95%CI:1.78-2.43],MACEs(HR:2.92,95%CI:1.85-4.60),and major bleeding(HR:4.60,95%CI:2.89-7.32)compared to non-frail patients.CONCLUSION Frailty is a pivotal determinant in the prediction of risk of mortality,development of MACEs,and major bleeding in elderly individuals undergoing percutaneous coronary intervention.

Fragile hearts:Unveiling the crucial layers of frailty in elderly patients undergoing percutaneous coronary interventions

Wang and Liu's systematic review of frailty among elderly patients undergoing percutaneous coronary intervention(PCI)revealed that patients with frailty have significantly higher risks of all-cause and in-hospital death,major undesirable cardiovascular events,and major haemorrhage.Frailty is associated with adverse events,prolonged hospital stays,increased complications,and elevated mortality risk due to diminished physiological reserves.Integrating frailty into risk assessment tools is crucial,and gait speed has emerged as a key predictor of frailty.Recognizing the impact of frailty leads to personalized and informed decisionmaking,and frailty assessments should be performed.This holistic approach can inform tailored interventions,thereby optimizing outcomes for this vulnerable population undergoing PCI.

Clinical study of a new nutritional index for predicting long-term prognosis in patients with coronary atherosclerotic heart disease following percutaneous coronary intervention

Background and Objective: Some patients continue to experience major adverse cardiovascular and cerebrovascular events (MACCE) after percutaneous coronary intervention (PCI) in frigid places. Indexes of inflammation and nutrition alone were shown to predict outcomes in patients with PCI. However, the clinical predictive value of mixed indicators is unclear. This study aimed to assess the predictive value of the albumin/neutrophil/lymphocyte ratio (NLR) on the long-term prognosis of patients with coronary heart disease (CHD) following percutaneous coronary intervention (PCI). Methods: A total of 608 post-PCI CHD patients were categorized into low- and high-index groups based on the optimal cut-off values for albumin and NLR. The primary outcome was a composite endpoint comprising all-cause mortality and major adverse cerebrovascular events. The secondary outcome was the comparison of the predictive efficiency of the new nutritional index, albumin/NLR, with that of albumin or NLR alone. Results: Over the five-year follow-up period, 45 patients experienced the composite endpoint. The incidence of endpoint events was significantly higher in the low-index group (12%) compared to the high-index group (4.9%). Receiver operating characteristic (ROC) curve analysis revealed that the albumin/NLR index had a larger area under the curve (AUC: 0.655) than albumin (AUC: 0.621) or NLR (AUC: 0.646), indicating superior predictive efficiency. The prognostic nutritional index had an AUC of 0.644, further supporting the enhanced predictive value of the albumin/NLR index over individual nutritional and inflammatory markers. Conclusion: The albumin/neutrophil/lymphocyte ratio is independently associated with the long-term prognosis of CHD patients post-PCI and demonstrates superior predictive efficiency compared to individual nutritional and inflammatory markers.

Bioresorbable stent unloading during percutaneous coronary intervention:Early detection and management

In this letter,we comment on a recent case report by Sun et al in the World Journal of Cardiology.The report describes the successful management of a rare complication:The unloading or detachment of a bioresorbable stent(BRS)during percutaneous coronary intervention(PCI)in a male patient.The unloading of BRS was detected via angiography and intravascular ultrasound(IVUS)imaging of the left coronary artery and left anterior descending artery.Although this case is interesting,the authors’report lacked crucial details.Specifically,insufficient information about the type of BRS used,potential causes of BRS unloading,or whether optical coherence tomography(OCT)imaging for coronary arteries was performed before,during,or after PCI.The OCT imaging of coronary arteries before PCI can potentially prevent BRS unloading due to its higher resolution compared to IVUS.In addition,despite detecting myocardial bridging during the PCI,the authors did not provide any details regarding this variation.Here we discuss the various types of BRS,the importance of OCT in PCI,and the clinical relevance of myocardial bridging.

Impact of primary percutaneous coronary intervention on ST-segment elevation myocardial infarction patients:A comprehensive analysis

BACKGROUND Myocardial infarction,particularly ST-segment elevation myocardial infarction(STEMI),is a key global mortality cause.Our study investigated predictors of mortality in 96 STEMI patients undergoing primary percutaneous coronary intervention at Erbil Cardiac Center.Multiple factors were identified influencing in-hospital mortality.Significantly,time from symptom onset to hospital arrival emerged as a decisive factor.Consequently,our study hypothesis is:"Reducing time from symptom onset to hospital arrival significantly improves STEMI prognosis."AIM To determine the key factors influencing mortality rates in STEMI patients.METHODS We studied 96 consecutive STEMI patients undergoing primary percutaneous coronary intervention(PPCI)at the Erbil Cardiac Center.Their clinical histories were compiled,and coronary evaluations were performed via angiography on admission.Data included comorbid conditions,onset of cardiogenic shock,complications during PPCI,and more.Post-discharge,one-month follow-up assessments were completed.Statistical significance was set at P<0.05.RESULTS Our results unearthed several significant findings.The in-hospital and 30-d mortality rates among the 96 STEMI patients were 11.2%and 2.3%respectively.On the investigation of independent predictors of in-hospital mortality,we identified atypical presentation,onset of cardiogenic shock,presence of chronic kidney disease,Thrombolysis In Myocardial Infarction grades 0/1/2,triple vessel disease,ventricular tachycardia/ventricular fibrillation,coronary dissection,and the no-reflow phenomenon.Specifically,the recorded average time from symptom onset to hospital arrival amongst patients who did not survive was significantly longer(6.92±3.86 h)compared to those who survived(3.61±1.67 h),P<0.001.These findings underscore the critical role of timely intervention in improving the survival outcomes of STEMI patients.CONCLUSION Our results affirm that early hospital arrival after symptom onset significantly improves survival rates in STEMI patients,highlighting the critical need for prompt intervention.

Comprehensive analysis of the impact of primary percutaneous coronary intervention on patients with ST-segment elevation myocardial infarction

This comprehensive analysis by Saeed and Faeq investigates the impact of primary percutaneous coronary intervention(pPCI)on mortality among patients with ST-segment elevation myocardial infarction(STEMI)at the Erbil Cardiac Center.Analyzing data from 96 consecutive STEMI patients,the study identified significant predictors of in-hospital mortality,emphasizing the critical impact of time of hospital arrival post-symptom onset on overall prognosis.Findings indicate that factors such as atypical presentation,cardiogenic shock,chronic kidney disease,and specific coronary complications are associated with higher mortality rates.The study underscores the necessity of prompt medical intervention for improving survival outcomes in STEMI patients,especially in the high-risk subgroup.This research offers valuable insights into optimizing STEMI management and enhancing patient survival rates through effective and timely pPCI.

Research Progress on the Depression Status and Nursing Intervention in Patients after Percutaneous Coronary Intervention

Percutaneous coronary intervention(PCI)is an effective treatment method for myocardial ischemic necrosis.Postoperative depression caused by PCI stress will adversely affect the prognosis of patients.This article reviews the current status and influencing factors of postoperative depression after PCI and summarizes the corresponding nursing interventions,to provide a literature reference to implement effective nursing interventions for depressed patients after clinical PCI.

Physical activity levels and predictors in patients following percutaneous coronary intervention: a cross-sectional study

Objective: To examine physical activity(PA) of post-percutaneous coronary intervention(PCI) patients and explore the demographic, clinical, and social psychological characteristics associated with PA levels. Methods: A total of 246 post-PCI patients from the Peking University Third Hospital in Beijing, China, were included in this crosssectional study through convenience sampling. Data were collected from a self-repor ted questionnaire. PA was categorized into low, moderate, or high levels. The ordinal multinomial logistic regression model was used to estimate the relationship among demographic, medical, and psychosocial characteristics. Results: The overall prevalence of low, moderate, and high PA was 20%, 70%, and 10%, respectively. For the domain-specific PA patterns, most par ticipants took par t in leisure-time PA(84.5%);walking was the most common PA. Increased motivation and selfefficacy, lower monthly income, and unemployment were predictors of high PA. Conclusions: PA levels in post-PCI patients was not optimal, and leisure-time PA had the highest par ticipation rate. Analyses of influencing factors can provide medical staff and health workers information to focus on high-risk groups and introduce more tailored interventions. Future studies can explore more regions, and ecological models can be introduced to study more influencing factors.

基于情绪ABC理论的正念训练对PCI患者的应用研究

目的探讨基于情绪ABC理论的正念干预对冠心病经皮冠状动脉介入治疗(PCI)术后患者的应用效果。方法选取2022年收治的80例冠心病PCI术后患者,随机分为试验组和对照组,每组40例。对照组给予心内科常规治疗与护理,试验组在常规护理的基础上给予基于情绪ABC理论的正念训练。分别于干预前、干预2个月后、干预6个月后评价患者的心肺功能[6 min步行距离(6 MWD)]、睡眠[匹兹堡睡眠质量指数(PSQI)]、焦虑抑郁[焦虑自评量表(SAS)、抑制自评量表(SDS)]、心脏不良事件的发生情况。结果干预前,2组患者6MWD、PSQI评分、SAS、SDS评分比较,差异均无统计学意义(P>0.05);干预2个月和6个月后,试验组6MWD、PSQI、SAS、SDS评分均优于对照组,差异有统计学意义(P<0.05);干预6个月后,2组患者心脏不良事件发生率比较,差异无统计学意义(P>0.05)。重复测量方差分析结果显示时间效应、组间效应、交互效应均有统计学意义(P<0.05)。结论基于情绪ABC理论的正念训练可提高患者的睡眠质量,改善负性情绪,提升心肺功能,值得临床推广应用。

早期心脏康复护理对急诊PCI术后患者心功能及生活质量的影响

目的探讨早期心脏康复护理在急诊经皮冠状动脉介入治疗术(PCI)术后患者中的应用效果。方法选取2020年4月至2021年2月在商丘市第一人民医院接受经桡动脉行急诊PCI治疗的急性心肌梗死(AMI)患者139例为研究对象,并将其分为对照组(70例)、干预组(69例)。给予对照组常规护理,干预组在此基础上接受早期心脏康复护理干预。比较两组患者心功能及生活质量评分。结果接受早期心脏康复护理干预的急诊PCI术后患者心功能评估(左心室射血分数、左心室舒张末期内径、心输出量、每搏心输出量)结果与对照组比较,差异无统计学意义(P>0.05)。接受早期心脏康复护理干预的急诊PCI术后患者,出院1个月后生活质量4个维度(一般健康状况、生理职能、社会功能、生理机能)评分均高于对照组(P<0.05)。结论早期心脏康复护理干预能提高急诊PCI术后患者生活质量,建议临床推广应用。

冠心病患者PCI术后发生支架内再狭窄的影响因素分析

目的分析冠心病患者经皮冠状动脉介入(PCI)术后发生支架内再狭窄(ISR)的相关影响因素。方法回顾性分析100例行PCI治疗的冠心病患者的临床资料,根据术后是否发生ISR分为发生组与未发生组,采用单因素分析和多因素Logistic回归分析探讨冠心病患者PCI术后发生ISR的危险因素。结果单因素和多因素Logistic回归分析显示,合并糖尿病、合并高血压、PCI术支架直径<3.5 mm、支架长度≥30 mm、支架数量≥2枚均为冠心病患者PCI术后发生ISR的危险因素(P<0.05)。结论合并糖尿病、合并高血压、PCI术支架直径过小、支架长度过长、多支架置入与冠心病患者PCI术后发生ISR密切相关。

稳定型心绞痛患者PCI术前冠脉生理指标与术后预后的关系研究

目的 探究稳定型心绞痛(SAP)患者经皮冠状动脉介入治疗(PCI)术前冠脉生理指标与术后预后的关系。方法 选取2020年2月至2022年5月期间陕西航天医院收治的68例SAP患者作为研究对象,所有患者均接受PCI术治疗,依据预后情况将患者分为预后良好组(n=40)和预后不良组(n=28),比较两组患者的基线资料,采用单因素及多因素Logistic回归分析PCI术后预后的影响因素,并绘制受试者工作特征曲线(ROC)分析PCI术前冠状动脉血流储备分数(FFR)、冠状动脉血流储备(CFR)、冠脉微循环阻力指数(IMR)对术后预后的预测效能。结果 经单因素及多因素Logistic回归分析结果显示,PCI术前FFR、CFR、IMR是PCI术后患者预后的独立危险因素(P<0.05);经ROC分析结果显示,PCI术前FFR、CFR、IMR预测术后预后的曲线下面积(AUC)分别为0.707、0.736、0.654,灵敏度分别为82.10%、67.90%、71.40%,特异度分别为52.50%、70.00%、57.50%,三者联合检测预测患者术后预后的AUC、灵敏度、特异度分别为0.909、89.30%、92.50%,均高于单一检测,差异均有统计学意义(P<0.05)。结论 PCI术前冠脉生理指标是SAP患者术后预后的影响因素,能有效评估SAP患者术后预后。

无导线起搏器联合PCI术治疗急性心肌梗死合并心律失常的疗效及对心电图、不良心血管事件的影响

目的:观察无导线起搏器联合经皮冠状动脉介入(PCI)术治疗急性心肌梗死(AMI)合并心律失常的疗效及对心电图参数、不良心血管事件的影响。方法:选取2020年6月—2021年6月我院收治的接受无导线起搏器联合PCI术治疗的80例AMI合并心律失常病人,统计无导线起搏器置入情况、PCI术手术效果、心功能、心肌灌注分级、起搏器电学参数、心电图参数、再灌注损伤与不良心血管事件。结果:介入治疗后全部病人均符合冠状动脉再通标准。80例均成功置入MicraTM无导线起搏器,起搏成功率为100%。治疗后左室舒张末期内径(LVEDD)、左室收缩末期内径(LVESD)、阈值、阻抗、QT间期均小于治疗前(P<0.05);左室射血分数(LVEF)、心排血量(CO)、感知、PR间期、QRS间期均大于治疗前(P<0.05);心肌组织灌注(TIMI)分级情况均优于治疗前(P<0.05),TIMI分级Ⅱ级以上的比例82.50%。80例中16例发生再灌注损伤,但无因再灌注损伤发生死亡者。随访6个月18例发生不良心血管事件。结论:无导线起搏器联合PCI术可改善AMI合并心律失常病人的心功能、心肌灌注分级、起搏器电学参数、心电图参数,冠状动脉再通率高、起搏成功率高,但可能发生再灌注损伤与不良心血管事件。

三维超声心动图右心室特征对急性左心室下壁心肌梗死患者PCI术后心力衰竭的预测价值

[目的]探究三维超声心动图右心室特征对急性左心室下壁心肌梗死(INFMI)患者经皮冠状动脉介入治疗(PCI)后心力衰竭(HF)的预测价值。[方法]纳入2018年10月-2021年10月261例INFMI患者,根据PCI术后1年随访记录分为心力衰竭组(n=42)和无心力衰竭组(n=219)。比较两组临床资料和心动图特征;采用LASSO-Logistic回归筛选术后HF发生的独立影响因素;构建列线图模型并验证。[结果]经筛选,在最优λ值处LASSO模型纳入INFMI患者游离壁中间段和整体纵向应变、流入道舒张期末容积和射血分数、体部舒张期末容积和射血分数。术后体部射血分数降低(截断值43.27%)、流入道射血分数降低(截断值51.49%)、整体纵向应变升高(截断值-13.52%)对HF有较高预测价值。联合年龄、Killip分级、N末端脑钠肽前体(NT-proBNP)构建列线图模型区分度较高,一致性指数0.981(95%CI:0.872~0.997),预测值与实际值拟合度较好。[结论]INFMI患者右心室整体纵向应变、流入道和体部射血分数联合年龄、Killip分级、NT-proBNP对PCI术后1年HF风险具有较高的预测价值,预测模型可作为临床决策工具使用。

中性粒细胞/淋巴细胞比值对冠状动脉粥样硬化性心脏病三支病变PCI术后患者预后的判断价值

目的:探讨中性粒细胞/淋巴细胞比值(NLR)在冠状动脉粥样硬化性心脏病(CAD)三支病变患者经皮冠状动脉介入术(PCI)术后预后评估中的价值。方法:回顾性收集2019年6月1日至2023年10月31日郑州大学第一附属医院收治并接受PCI的CAD三支病变患者的临床资料,根据NLR中位数分为高NLR组(n=209)和低NLR组(n=208),绘制Kaplan-Meier风险曲线,采用Cox回归分析NLR与不良结局的关系。结果:在完全调整模型中,NLR对于全因性死亡和主要不良心血管事件的HR(95%CI)分别为1.057(1.021~1.092)和1.031(1.004~1.055),而高NLR组的HR(95%CI)分别为2.730(1.244~6.009)和1.883(1.171~3.033)。NLR对于全因性死亡和主要不良心血管事件的曲线下面积(95%CI)、敏感度、特异度分别为0.823(0.782~0.863)、0.886、0.312和0.750(0.658~0.842)、0.692、0.324,具有良好的预测价值。结论:NLR可作为CAD三支病变患者PCI术后预后的可靠预测指标。

THR、MHR和NHR对冠状动脉狭窄程度和行PCI的预测价值

目的 探讨总胆固醇与高密度脂蛋白胆固醇比值(THR)、单核细胞与高密度脂蛋白胆固醇比值(MHR)和中性粒细胞与高密度脂蛋白胆固醇比值(NHR)对患者冠状动脉狭窄程度和行经皮冠状动脉介入(PCI)治疗的预测价值。方法 回顾性选取2021年6月至2023年6月在新疆医科大学第一附属医院行冠状动脉造影的患者,严格纳入排除标准筛选,共纳入6 281例患者,分为PCI组和non-PCI组,收集所有患者的临床资料、实验室检查结果及介入治疗资料。采用Pearson相关性分析评估THR、MHR和NHR与冠状动脉狭窄程度之间的关联。使用二元Logistic逐步回归和受试者工作特征(ROC)曲线评估THR、MHR和NHR单一指标和联合指标对冠心病患者行PCI治疗的影响因素和预测价值。结果 与Non-PCI组比较,PCI组年龄偏大,男性占比、患糖尿病占比、THR、MHR、NHR、Gensini评分高于Non-PCI组,既往支架植入比例少于Non-PCI组(P<0.05)。Pearson相关分析结果显示,THR(r=0.351,P<0.001)、MHR(r=0.192,P<0.001)和NHR(r=0.236,P<0.001)水平与冠状动脉狭窄程度的Gensini评分均存在显著正相关关系。多因素Logistic回归结果显示,年龄>50岁、男性、患糖尿病、THR、MHR、NHR是冠心病患者行PCI独立危险因素,既往支架植入史是冠心病患者行PCI的保护因素。ROC曲线结果显示,THR、MHR和NHR三者联合曲线下面积(AUC)最大(AUC=0.809,95%CI:0.798~0.820)。结论 THR、MHR和NHR与冠状动脉狭窄程度具有相关性,对评估冠心病行PCI治疗有较强的临床应用价值。

冠心病病人PCI术后1年出血危险因素的模型构建和验证

目的:基于LASSO-Logistic回归分析冠心病病人经皮冠状动脉介入(PCI)术后1年出血的危险因素,并建立Nomogram预测模型,以便临床采取及时、有效的干预方案。方法:选取2021年1月—12月在我院行PCI术的226例冠心病病人为研究对象,依据PCI术后1年是否出血分为出血组、未出血组。采用LASSO-Logistic回归筛选PCI术后1年出血的危险因素,进一步构建Nomogram预测模型。利用受试者工作特征(ROC)曲线、校准曲线验证Nomogram预测模型的价值。结果:PCI术后1年226例冠心病病人出血发生率为11.95%;年龄≥60岁、有消化道病史、慢性肾功能不全、使用血管闭合器、球囊扩张次数、支架术后抗血小板药物停药模式(PARIS)评分、支架术后双重抗血小板治疗病人出血并发症预测(PRECISE-DAPT)评分为PCI术后1年出血的危险因素(P<0.05);Nomogram预测模型预测PCI术后1年出血的ROC曲线下面积为0.959。结论:年龄≥60岁、有消化道病史、慢性肾功能不全、使用血管闭合器、球囊扩张次数、PARIS评分、PRECISE-DAPT评分为冠心病病人PCI术后1年出血的危险因素,基于LASSO-Logistic回归分析建立的Nomogram预测模型对PCI术后1年出血具有一定预测价值,临床应筛查高危人群并实施严格观察,制定合理治疗措施,以降低出血风险。

冠心病患者PCI术后康复强度-时间依从性轨迹及预测因素分析

目的探究冠心病患者经皮冠状动脉介入治疗(PCI)术后康复强度-时间依从性轨迹及其预测因素。方法选择2022年4月—2023年4月于秦皇岛市第一医院行PCI的冠心病患者120例为研究对象,进行为期1年的随访,使用运动日志记录监测强度-时间依从性。使用潜类别增长模型(LCGM)确定术后康复强度-时间依从性的发展轨迹。logistic回归分析不同轨迹类别的预测因素。结果LCGM将患者术后康复强度-时间依从性变化分为低-下降组(n=35,29.17%)、高-上升组(n=15,12.50%)、持续依从组(n=70,58.33%)。以低-下降组为参照组,高-上升组和持续依从组患者年龄更大、病程更短、冠状动脉病变程度更轻、心功能分级更低、抑郁程度更轻(P<0.05);持续依从组患者的医患关系更好(P<0.05)。结论冠心病患者PCI术后康复强度-时间依从性呈多类别曲线增长趋势,根据其时变特点及影响因素,实施强化干预,可提高患者康复依从性水平。

衰弱状态与老年冠心病患者PCI术后心功能及其预后

目的分析老年冠心病患者经皮冠脉介入治疗(PCI)后的衰弱状态与心肌损伤、心脏结构功能的关系,并评估其对长期预后的价值。方法纳入2020年1月至2022年1月在安徽省池州市人民医院行PCI的老年冠心病患者348例。术后通过改良Tilburg衰弱量表进行评估,将总分≥5分的患者设置为衰弱组(n=152),其他患者为非衰弱组(n=196)。比较两组患者手术前后的心肌损伤标志物[B型利钠肽(BNP)、心肌肌钙蛋白T(cTnT)、肌酸激酶同工酶(CK-MB)]和心功能指标[左心室收缩末内径(LVESD)、左心室舒张末内径(LVEDD)、左心室后壁厚度(LVPW)、左心室射血分数(LVEF)]。随访2年,对比两组发生心血管不良事件的情况(心源性休克、心源性死亡、严重心力衰竭、急性心肌梗死)。通过Pearson相关性分析患者心肌损伤及心脏结构功能与衰弱状态的关系,ROC曲线评估Tilburg评分对患者预后情况的诊断效能。结果术后非衰弱组心肌损伤标志物水平、LVESD、LVEDD低于衰弱组,LVEF高于衰弱组(均P<0.05)。Tilburg评分与心肌损伤情况、LVESD、LVEDD呈正相关,与LVEF呈负相关;且Tilburg评分对患者预后评估的ROC曲线下面积为0.982。结论老年冠心病患者PCI术后衰弱状态与心肌损伤及心脏结构功能有显著的相关性,对长期预后有较高的预测价值。