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Analysis of the Emergency Rescue Nursing Intervention Effect and Rescue Success Rate for Patients with Traumatic Hemorrhagic Shock
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作者 Lingli He 《Journal of Clinical and Nursing Research》 2024年第10期81-87,共7页
Objective:To analyze the value of emergency rescue nursing intervention in the care of patients with traumatic hemorrhagic shock and its impact on the success rate of rescue efforts.Methods:A total of 80 patients with... Objective:To analyze the value of emergency rescue nursing intervention in the care of patients with traumatic hemorrhagic shock and its impact on the success rate of rescue efforts.Methods:A total of 80 patients with traumatic hemorrhagic shock were selected as samples,with the timeframe from July 2022 to July 2023.The patients were randomly divided into two groups using a random number table method.Group A received emergency rescue nursing,while Group B received routine nursing care.The success rate of rescue,rescue indicators,complication rates,and family satisfaction with nursing care were compared between the two groups.Results:The rescue success rate in Group A was higher than in Group B(P<0.05);the total blood loss in Group A was less,and the rescue time,full transportation time,and hospitalization time were shorter than in Group B(P<0.05);the complication rate of patients with traumatic hemorrhagic shock in Group A was lower than in Group B(P<0.05);the family satisfaction with emergency nursing care in Group A was higher than in Group B(P<0.05).Conclusion:Emergency rescue interventions for patients with traumatic hemorrhagic shock can reduce blood loss,shorten rescue times,and improve the success rate of shock rescue,providing a safe and effective approach. 展开更多
关键词 Emergency rescue nursing Traumatic hemorrhagic shock rescue success rate
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Vonoprazan-amoxicillin dual regimen with Saccharomyces boulardii as a rescue therapy for Helicobacter pylori:Current perspectives and implications 被引量:1
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作者 Valerie Josephine Dirjayanto Jessica Audrey Daniel Martin Simadibrata 《World Journal of Gastroenterology》 SCIE CAS 2024年第10期1280-1286,共7页
Yu et al’s study in the World Journal of Gastroenterology(2023)introduced a novel regimen of Vonoprazan-amoxicillin dual therapy combined with Saccharomyces boulardii(S.boulardii)for the rescue therapy against Helico... Yu et al’s study in the World Journal of Gastroenterology(2023)introduced a novel regimen of Vonoprazan-amoxicillin dual therapy combined with Saccharomyces boulardii(S.boulardii)for the rescue therapy against Helicobacter pylori(H.pylori),a pathogen responsible for peptic ulcers and gastric cancer.Vonoprazan is a potassium-competitive acid blocker renowned for its rapid and long-lasting acid suppression,which is minimally affected by mealtime.Compared to proton pump inhibitors,which bind irreversibly to cysteine residues in the H+/K+-ATPase pump,Vonoprazan competes with the K+ions,prevents the ions from binding to the pump and blocks acid secretion.Concerns with increasing antibiotic resistance,effects on the gut microbiota,patient compliance,and side effects have led to the advent of a dual regimen for H.pylori.Previous studies suggested that S.boulardii plays a role in stabilizing the gut barrier which improves H.pylori eradication rate.With an acceptable safety profile,the dual-adjunct regimen was effective regardless of prior treatment failure and antibiotic resistance profile,thereby strengthening the applicability in clinical settings.Nonetheless,S.boulardii comes in various formulations and dosages,warranting further exploration into the optimal dosage for supplementation in rescue therapy.Additionally,larger,randomized,double-blinded controlled trials are warranted to confirm these promising results. 展开更多
关键词 Vonoprazan Saccharomyces boulardii Helicobacter pylori rescue therapy Eradication rate
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Real-time Rescue Target Detection Based on UAV Imagery for Flood Emergency Response 被引量:1
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作者 ZHAO Bofei SUI Haigang +2 位作者 ZHU Yihao LIU Chang WANG Wentao 《Journal of Geodesy and Geoinformation Science》 CSCD 2024年第1期74-89,共16页
Timely acquisition of rescue target information is critical for emergency response after a flood disaster.Unmanned Aerial Vehicles(UAVs)equipped with remote sensing capabilities offer distinct advantages,including hig... Timely acquisition of rescue target information is critical for emergency response after a flood disaster.Unmanned Aerial Vehicles(UAVs)equipped with remote sensing capabilities offer distinct advantages,including high-resolution imagery and exceptional mobility,making them well suited for monitoring flood extent and identifying rescue targets during floods.However,there are some challenges in interpreting rescue information in real time from flood images captured by UAVs,such as the complexity of the scenarios of UAV images,the lack of flood rescue target detection datasets and the limited real-time processing capabilities of the airborne on-board platform.Thus,we propose a real-time rescue target detection method for UAVs that is capable of efficiently delineating flood extent and identifying rescue targets(i.e.,pedestrians and vehicles trapped by floods).The proposed method achieves real-time rescue information extraction for UAV platforms by lightweight processing and fusion of flood extent extraction model and target detection model.The flood inundation range is extracted by the proposed method in real time and detects targets such as people and vehicles to be rescued based on this layer.Our experimental results demonstrate that the Intersection over Union(IoU)for flood water extraction reaches an impressive 80%,and the IoU for real-time flood water extraction stands at a commendable 76.4%.The information on flood stricken targets extracted by this method in real time can be used for flood emergency rescue. 展开更多
关键词 UAV flood extraction target rescue detection real time
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Substitutions of stem-loop subdomains in internal ribosome entry site of Senecavirus A:Impacts on rescue of sequence-modifying viruses
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作者 Qianqian Wang Jie Wang +5 位作者 Lei Zhang Xiaoxiao Duan Lijie Zhu Youming Zhang Yan Li Fuxiao Liu 《Journal of Integrative Agriculture》 SCIE CAS CSCD 2024年第7期2391-2406,共16页
Senecavirus A(SVA)has a positive-sense,single-stranded RNA genome.Its 5´untranslated region harbors an internal ribosome entry site(IRES),comprising 10 larger or smaller stem-loop structures(including a pseudokno... Senecavirus A(SVA)has a positive-sense,single-stranded RNA genome.Its 5´untranslated region harbors an internal ribosome entry site(IRES),comprising 10 larger or smaller stem-loop structures(including a pseudoknot)that have been demonstrated to be well conserved.However,it is still unclear whether each stem-loop subdomain,such as a single stem or loop,is also highly conserved.To clarify this issue in the present study,a set of 29 SVA cDNA clones were constructed by site-directed mutagenesis(SDM)on the IRES.The SDM-modified scenarios included:(1)stem-formed complementary sequences exchanging with each other;(2)loop transversion;(3)loop transition;and(4)point mutations.All cDNA clones were separately transfected into cells for rescuing viable viruses,whereas only four SVAs of interest could be recovered,and were genetically stable during 20 passages.One progeny grew significantly slower than the other three did.The dual-luciferase reporter assay showed that none of the SDM-modified IRESes significantly inhibited the IRES activity.Our previous study indicated that a single motif from any of the ten stem structures,if completely mutated,would cause the failure of virus recovery.Interestingly,our present study revealed three stem structures,whose individual complementary sequences could exchange with each other to rescue sequence-modifying SVAs.Moreover,one apical loop was demonstrated to have the ability to tolerate its own full-length transition,also having no impact on the recovery of sequence-modifying SVA.The present study suggested that not every stem-loop structure was strictly conserved in its conformation,while the full-length IRES itself was well conserved.This provides a new research direction on interaction between the IRES and many factors. 展开更多
关键词 SVA HCV IRES HCV-like IRES stem-loop structure cDNA clone virus rescue mutation
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An Improved Iterated Greedy Algorithm for Solving Rescue Robot Path Planning Problem with Limited Survival Time
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作者 Xiaoqing Wang Peng Duan +1 位作者 Leilei Meng Kaidong Yang 《Computers, Materials & Continua》 SCIE EI 2024年第7期931-947,共17页
Effective path planning is crucial for mobile robots to quickly reach rescue destination and complete rescue tasks in a post-disaster scenario.In this study,we investigated the post-disaster rescue path planning probl... Effective path planning is crucial for mobile robots to quickly reach rescue destination and complete rescue tasks in a post-disaster scenario.In this study,we investigated the post-disaster rescue path planning problem and modeled this problem as a variant of the travel salesman problem(TSP)with life-strength constraints.To address this problem,we proposed an improved iterated greedy(IIG)algorithm.First,a push-forward insertion heuristic(PFIH)strategy was employed to generate a high-quality initial solution.Second,a greedy-based insertion strategy was designed and used in the destruction-construction stage to increase the algorithm’s exploration ability.Furthermore,three problem-specific swap operators were developed to improve the algorithm’s exploitation ability.Additionally,an improved simulated annealing(SA)strategy was used as an acceptance criterion to effectively prevent the algorithm from falling into local optima.To verify the effectiveness of the proposed algorithm,the Solomon dataset was extended to generate 27 instances for simulation.Finally,the proposed IIG was compared with five state-of-the-art algorithms.The parameter analysiswas conducted using the design of experiments(DOE)Taguchi method,and the effectiveness analysis of each component has been verified one by one.Simulation results indicate that IIGoutperforms the compared algorithms in terms of the number of rescue survivors and convergence speed,proving the effectiveness of the proposed algorithm. 展开更多
关键词 rescue robot path planning life strength improved iterative greedy algorithm problem-specific swap operators
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Failure to Rescue as a Quality Metric in Congenital Heart Surgeries in a High-Complexity Service Provider Institution Located in a Middle-Income Country
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作者 Gustavo Cruz Santiago Pedroza +3 位作者 Juan F.Vélez Jessica Largo Juan F.Tejada Jorge H.Mejía-Mantilla 《Congenital Heart Disease》 SCIE 2024年第2期207-218,共12页
Background:Failure to rescue has been an effective quality metric in congenital heart surgery.Conversely,mor-bidity and mortality depend greatly on non-modifiable individual factors and have a weak correlation with be... Background:Failure to rescue has been an effective quality metric in congenital heart surgery.Conversely,mor-bidity and mortality depend greatly on non-modifiable individual factors and have a weak correlation with better-quality performance.We aim to measure the complications,mortality,and risk factors in pediatric patients undergoing congenital heart surgery in a high-complexity institution located in a middle-income country and compare it with other institutions that have conducted a similar study.Methods:A retrospective observational study was conducted in a high-complexity service provider institution,in Cali,Colombia.All pediatric patients undergoing any congenital heart surgery between 2019 and 2022 were included.The main outcomes evaluated in the study were complication,mortality,and failure to rescue rate.Univariate and multivariate logistic regression analysis was performed with mortality as the outcome variable.Results:We evaluated 308 congenital heart sur-geries.Regarding the outcomes,201(65%)complications occurred,23(7.5%)patients died,and the FTR of the entire cohort was 11.4%.The presence of a postoperative complication(OR 14.88,CI 3.06–268.37,p=0.009),age(OR 0.79,CI 0.57–0.96,p=0.068),and urgent/emergent surgery(OR 8.14,CI 2.97–28.66,p<0.001)were the most significant variables in predicting mortality.Conclusions:Failure to rescue is an effective and comparable quality measure in healthcare institutions and is the major contributor to postoperative mortality in congenital heart surgeries.Despite our higher mortality and complication rate,we obtained a comparable failure to rescue rate to high-income countries’health institutions. 展开更多
关键词 Congenital heart surgery COMPLICATION mortality failure to rescue quality metric
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Rescue from complications after pancreaticoduodenectomies at a low-volume Caribbean center:Value of tailored peri-pancreatectomy protocols
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作者 Shamir O Cawich Elijah Dixon +7 位作者 Parul J Shukla Shailesh V Shrikhande Rahul R Deshpande Fawwaz Mohammed Neil W Pearce Wesley Francis Shaneeta Johnson Johann Bujhawan 《World Journal of Gastrointestinal Surgery》 SCIE 2024年第3期681-688,共8页
BACKGROUND Pancreaticoduodenectomy(PD)is a technically complex operation,with a re-latively high risk for complications.The ability to rescue patients from post-PD complications is as a recognized quality measure.Tail... BACKGROUND Pancreaticoduodenectomy(PD)is a technically complex operation,with a re-latively high risk for complications.The ability to rescue patients from post-PD complications is as a recognized quality measure.Tailored protocols were instituted at our low volume facility in the year 2013.AIM To document the rate of rescue from post-PD complications with tailored protocols in place as a measure of quality.METHODS A retrospective audit was performed to collect data from patients who experienced major post-PD complications at a low volume pancreatic surgery unit in Trinidad and Tobago between January 1,2013 and June 30,2023.Stan-dardized definitions from the International Study Group of Pancreatic Surgery were used to define post-PD complications,and the modified Clavien-Dindo classification was used to classify post-PD complications.RESULTS Over the study period,113 patients at a mean age of 57.5 years(standard deviation[SD]±9.23;range:30-90;median:56)underwent PDs at this facility.Major complications were recorded in 33(29.2%)patients at a mean age of 53.8 years(SD:±7.9).Twenty-nine(87.9%)patients who experienced major morbidity were salvaged after aggre-ssive treatment of their complication.Four(3.5%)died from bleeding pseudoaneurysm(1),septic shock secondary to a bile leak(1),anastomotic leak(1),and myocardial infarction(1).There was a significantly greater salvage rate in patients with American Society of Anesthesiologists scores≤2(93.3%vs 25%;P=0.0024).CONCLUSION This paper adds to the growing body of evidence that volume alone should not be used as a marker of quality for patients requiring PD.Despite low volumes at our facility,we demonstrated that 87.9%of patients were rescued from major complications.We attributed this to several factors including development of rescue protocols,the competence of the pancreatic surgery teams and continuous,and adaptive learning by the entire institution,cul-minating in the development of tailored peri-pancreatectomy protocols. 展开更多
关键词 PANCREAS COMPLICATION rescue Failure MORBIDITY Mortality PANCREATICODUODENECTOMY
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Benchmarking YOLOv5 models for improved human detection in search and rescue missions
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作者 Namat Bachir Qurban Ali Memon 《Journal of Electronic Science and Technology》 EI CAS CSCD 2024年第1期70-80,共11页
Drone or unmanned aerial vehicle(UAV)technology has undergone significant changes.The technology allows UAV to carry out a wide range of tasks with an increasing level of sophistication,since drones can cover a large ... Drone or unmanned aerial vehicle(UAV)technology has undergone significant changes.The technology allows UAV to carry out a wide range of tasks with an increasing level of sophistication,since drones can cover a large area with cameras.Meanwhile,the increasing number of computer vision applications utilizing deep learning provides a unique insight into such applications.The primary target in UAV-based detection applications is humans,yet aerial recordings are not included in the massive datasets used to train object detectors,which makes it necessary to gather the model data from such platforms.You only look once(YOLO)version 4,RetinaNet,faster region-based convolutional neural network(R-CNN),and cascade R-CNN are several well-known detectors that have been studied in the past using a variety of datasets to replicate rescue scenes.Here,we used the search and rescue(SAR)dataset to train the you only look once version 5(YOLOv5)algorithm to validate its speed,accuracy,and low false detection rate.In comparison to YOLOv4 and R-CNN,the highest mean average accuracy of 96.9%is obtained by YOLOv5.For comparison,experimental findings utilizing the SAR and the human rescue imaging database on land(HERIDAL)datasets are presented.The results show that the YOLOv5-based approach is the most successful human detection model for SAR missions. 展开更多
关键词 Unmanned aerial vehicle(UAV) Search and rescue(SAR) You look only once(YOLO)model You only look once version 5 (YOLOv5)
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The Association between Fear of COVID-19,Obsession with COVID-19,and Post Traumatic Stress Disorder in Korean Emergency Rescue Firefighters:A Cross-Sectional Study
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作者 Yun-Jung Choi Heewon Song 《International Journal of Mental Health Promotion》 2024年第6期475-480,共6页
During the rapid spread of COVID-19,first responders are at risk of being exposed to COVID-19 due to their role in providing first aid and responding to an unspecified number of people.This uncertainty can have advers... During the rapid spread of COVID-19,first responders are at risk of being exposed to COVID-19 due to their role in providing first aid and responding to an unspecified number of people.This uncertainty can have adverse mental health effects,such as increased anxiety and fear.This study aimed to investigate the degree of association between fear of COVID-19,obsession with COVID-19,and post-traumatic stress disorder(PTSD)in emergency rescue firefighters.The participants were 150 emergency rescue firefighters working in Region S,Korea.They filled out self-report questionnaires:The data obtained through the Fear of COVID-19 Scale,Obsession with COVID-19 Scale,and Impact of Event Scale-Revised Korean version were subjected to nonparametric statistical analysis using SPSS WIN 25.0.The study found a significant correlation between emergency rescue firefighters’fear of COVID-19,obsession with COVID-19,and PTSD.Fear and obsession with COVID-19 were higher among first responder firefighters who were directly involved in COVID-19-related tasks.Furthermore,a one-point increase in obsession was associated with a 2.837-point increase in PTSD.Based on the results,we found that there is a need for effective control of obsessions and fears among first responder firefighters during COVID-19,and we suggest that there is a need for mental health care for first responder firefighters during the pandemic through the development and support of programs to prevent and mitigate obsessions. 展开更多
关键词 COVID-19 emergency rescue firefighters fear of COVID-19 mental health promotion obsession with COVID-19 PTSD
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Assessment of Meteorological Threats to the Coordinated Search and Rescue of Unmanned/Manned Aircraft
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作者 Fei YAN Chuan LI +2 位作者 Xiaoyi FU Kefeng WU Yuying LI 《Meteorological and Environmental Research》 2024年第1期27-29,37,共4页
The architecture and working principle of coordinated search and rescue system of unmanned/manned aircraft,which is composed of manned/unmanned aircraft and manned aircraft,were first introduced,and they can cooperate... The architecture and working principle of coordinated search and rescue system of unmanned/manned aircraft,which is composed of manned/unmanned aircraft and manned aircraft,were first introduced,and they can cooperate with each other to complete a search and rescue task.Secondly,a threat assessment method based on meteorological data was proposed,and potential meteorological threats,such as storms and rainfall,can be predicted by collecting and analyzing meteorological data.Finally,an experiment was carried out to evaluate the performance of the proposed method in different scenarios.The experimental results show that the coordinated search and rescue system of unmanned/manned aircraft can be used to effectively assess meteorological threats and provide accurate search and rescue guidance. 展开更多
关键词 Unmanned/manned aircraft Coordinated search and rescue Assessment of meteorological threats Meteorological data
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Structural Design Study of Air-Dropped Unmanned Maritime Mobile Search and Rescue Platforms
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作者 Zhiming Feng Lingzhe Kong Zhongyu Cui 《Journal of Electronic Research and Application》 2024年第3期234-242,共9页
In order to improve the efficiency and safety of search and rescue(SAR)at sea,this paper proposes a kind of emergency rapid rescue unmanned craft(air-dropped unmanned maritime motorized search and rescue platform)that... In order to improve the efficiency and safety of search and rescue(SAR)at sea,this paper proposes a kind of emergency rapid rescue unmanned craft(air-dropped unmanned maritime motorized search and rescue platform)that can be delivered by a large transport aircraft.This paper studies the structural design scheme of the platform,and the main scale of the platform,the choice of power system and the impact resistance performance are considered in the design process to ensure its rapid response and effective rescue capability under complex sea conditions.Simulation results show that the platform can withstand the impact of air injection into the water and the shipboard equipment can operate normally under the impact load,thus verifying the feasibility and safety of the design.This study serves to improve the maritime search and rescue system and enhance the oceanic emergency response capability. 展开更多
关键词 Maritime search and rescue Unmanned maritime platform Maritime airdrop Impact resistance simulation
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CAN-based Control System Design on Minor-caliber Deep Well Rescue Robot
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作者 袁越 郑小千 史丽蕊 《Journal of Measurement Science and Instrumentation》 CAS 2011年第2期124-126,共3页
By introdming a small-caliber deep well rescue robot, a hold-hug pattern rescue mechanism was brought forward. In order to reduce the volmne, the trader-well rescue imclmnism is modularizing designed. At the same tira... By introdming a small-caliber deep well rescue robot, a hold-hug pattern rescue mechanism was brought forward. In order to reduce the volmne, the trader-well rescue imclmnism is modularizing designed. At the same tirae, the audio and video systyems, the illumination system and the ventilation system are expatiated. The rescuing robot can rescue the falling person in the deep well, it can save much manateral resources and time. It's really an ideal rescue device for the small-caliber fall. 展开更多
关键词 small-caliber deep well rescue robot hold-hug pattern rescue rescue device
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Decision model and algorithm for traffic rescue resource dispatching on expressway 被引量:6
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作者 柴干 朱苍晖 +1 位作者 万水 濮居一 《Journal of Southeast University(English Edition)》 EI CAS 2009年第2期252-256,共5页
In order to solve the problems of potential incident rescue on expressway networks, the opportunity cost-based method is used to establish a resource dispatch decision model. The model aims to dispatch the rescue reso... In order to solve the problems of potential incident rescue on expressway networks, the opportunity cost-based method is used to establish a resource dispatch decision model. The model aims to dispatch the rescue resources from the regional road networks and to obtain the location of the rescue depots and the numbers of service vehicles assigned for the potential incidents. Due to the computational complexity of the decision model, a scene decomposition algorithm is proposed. The algorithm decomposes the dispatch problem from various kinds of resources to a single resource, and determines the original scene of rescue resources based on the rescue requirements and the resource matrix. Finally, a convenient optimal dispatch scheme is obtained by decomposing each original scene and simplifying the objective function. To illustrate the application of the decision model and the algorithm, a case of the expressway network is studied on areas around Nanjing city in China and the results show that the model used and the algorithm proposed are appropriate. 展开更多
关键词 dispatch decision model scene decomposition algorithm traffic rescue resource EXPRESSWAY
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Location of emergency rescue center based on SIR epidemiological model 被引量:3
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作者 胡家香 赵林度 江亿平 《Journal of Southeast University(English Edition)》 EI CAS 2007年第S1期89-93,共5页
In view of the pressure time of emergency rescue against the infectious diseases,a mathematical model to optimize the location of emergency rescue centers is proposed.The model takes full account of the spread functio... In view of the pressure time of emergency rescue against the infectious diseases,a mathematical model to optimize the location of emergency rescue centers is proposed.The model takes full account of the spread function of infectious diseases,the cycle of pulse vaccination,the distance between the demand area and the emergency rescue centers,as well as the building and maintenance cost for the emergency rescue center,and so on.At the same time,the model integrates the traditional location selection models which are the biggest cover model,the p-center model and the p-median model,and it embodies the principles of fairness and efficiency for the emergency center location.Finally,a computation of an example arising from practice provides satisfactory results. 展开更多
关键词 susceptible-infective-removed(SIR)model pulse vaccination LOCATION emergency rescue p-median model
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Optimal dispatching method of traffic incident rescue resource for freeway network 被引量:1
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作者 柴干 冉旭 夏井新 《Journal of Southeast University(English Edition)》 EI CAS 2013年第3期336-341,共6页
An optimal resource dispatching method is proposed to solve the multiple-response problem under the conditions of potential incidents on freeway networks.Travel time of the response vehicle is selected instead of rout... An optimal resource dispatching method is proposed to solve the multiple-response problem under the conditions of potential incidents on freeway networks.Travel time of the response vehicle is selected instead of route distance as the weight to reflect the impact of traffic conditions on the decisions of rescue resources.According to the characteristics of different types of rescue vehicles the dispatching decision-making time is revised to show the heterogeneity among different rescue vehicle dispatching modes. The genetic algorithm is used to obtain the solutions to the rescue resources dispatching model. A case study shows that the proposed method can accurately reveal the impact of potential incidents on the costs of rescues according to the variations in the types and quantities of rescue resources and the optimal dispatching plan with respect to potential incidents can be obtained.The proposed method is applicable in real world scenarios. 展开更多
关键词 optimal dispatching potential incident GENETICALGORITHM rescue resource freeway network
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传染性法氏囊病病毒Rescue技术及其应用的研究进展
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作者 陈义平 崔治中 《预防兽医学进展》 2001年第4期12-15,共4页
传染性法氏囊病病毒(Infectious bursal disease virus,IBDV)是一种小的、无囊膜的双股RNA病毒,基因组含A、B两个片段,大片段A(3.2~3.4kb)由两端的非编码区以及两个部分重叠的开放阅读框架(ORF)组成,其中较大的ORE编码一个分子量约为11... 传染性法氏囊病病毒(Infectious bursal disease virus,IBDV)是一种小的、无囊膜的双股RNA病毒,基因组含A、B两个片段,大片段A(3.2~3.4kb)由两端的非编码区以及两个部分重叠的开放阅读框架(ORF)组成,其中较大的ORE编码一个分子量约为110kDa的多聚蛋白,该多聚蛋白经几步裂解加工后形成VP2、VP3和VP4蛋白,较小的ORF编码一个17kDa的非结构蛋白VP5,基因组小片段B(约2.8kb)编码90kDa的具有多功能酶活性的VP1. 展开更多
关键词 动物疾病 传染性法氏囊病病毒 RNA病毒 rescue技术 应用研究
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Analysis on the Demand and Countermeasures of Air Ground Coordination in China’s Aviation Medical Rescue
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作者 Jun Gao Shuwen Chen 《World Journal of Engineering and Technology》 2022年第4期790-797,共8页
Compared with ground first aid, aviation medical rescue has better advantages in mountain disaster relief, remote transfer and rapid medical rescue response, which is an effective supplement to ground medical first ai... Compared with ground first aid, aviation medical rescue has better advantages in mountain disaster relief, remote transfer and rapid medical rescue response, which is an effective supplement to ground medical first aid. China’s aviation medical rescue is in its infancy, compared with the level of developed countries there is a big gap. Based on the development and characteristics of aviation medical rescue in China, this paper combs the process of air-ground cooperative rescue, analyzes the demand and current situation of air-ground cooperative rescue in aviation medical rescue in China, and puts forward some countermeasures to improve the ability of aviation medical rescue in China. 展开更多
关键词 Aviation Medical rescue rescue System Three-Dimensional Coordination
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Third-line rescue therapy for Helicobacter pylori infection 被引量:31
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作者 Rossella Cianci Massimo Montalto +2 位作者 Franco Pandolfi Giovan Battista Gasbarrini Giovanni Cammarota 《World Journal of Gastroenterology》 SCIE CAS CSCD 2006年第15期2313-2319,共7页
H pylori gastric infection is one of the most prevalent infectious diseases worldwide. The discovery that most upper gastrointestinal diseases are related to Hpylori infection and therefore can be treated with antibio... H pylori gastric infection is one of the most prevalent infectious diseases worldwide. The discovery that most upper gastrointestinal diseases are related to Hpylori infection and therefore can be treated with antibiotics is an important medical advance. Currently, a first-line triple therapy based on proton pump inhibitor (PPI) or ranitidine bismuth citrate (RBC) plus two antibiotics (darithromycin and amoxicillin or nitroimidazole) is recommended by all consensus conferences and guidelines. Even with the correct use of this drug combination, infection can not be eradicated in up to 23% of patients. Therefore, several second line therapies have been recommended. A 7 d quadruple therapy based on PPI, bismuth, tetracycline and metronidazole is the more frequently accepted. However, with second-line therapy, bacterial eradication may fail in up to 40% of cases. When Hpylori eradication is striclly indicated the choice of further treatment is controversial. Currently, a standard third-line therapy is lacking and various protocols have been proposed. Even after two consecutive failures, the most recent literature data have demonsbated that Hpylori eradication can be achieved in almost all patients, even when antibiotic susceptibility is not tested. Different possibilities of empirical treatment exist and the available third-line strategies are herein reviewed. 展开更多
关键词 Helicobacter pylori Third-line rescue therapy Antimicrobial resistance LEVOFLOXACIN RIFABUTIN FURAZOLIDONE DOXYCYCLINE
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Furazolidone,amoxicillin,bismuth and rabeprazole quadruple rescue therapy for the eradication of Helicobacter pylori 被引量:26
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作者 Hong Cheng Fu-Lian Hu 《World Journal of Gastroenterology》 SCIE CAS CSCD 2009年第7期860-864,共5页
AIM: To compare the efficacy and side effect profiles of three furazolidone and amoxicillin-based quadruple rescue therapies for the eradication of Helicobacter pylori (H pylonS. METHODS: Patients who failed in the... AIM: To compare the efficacy and side effect profiles of three furazolidone and amoxicillin-based quadruple rescue therapies for the eradication of Helicobacter pylori (H pylonS. METHODS: Patients who failed in the Hpylori eradication therapy for at least one course were randomly allocated into three groups. Group A received rebaprazole 10 mg+ amoxicillin 1 g + furazolidone 100 mg, and bismuth subcitrate 220 mg, twice daily for 1 wk; group B received the same regimen of group A but for 2 wk; and group C received the same regimen of group B, but furazolidone was replaced by furazolidone 100 mg three times daily. To record the side effect profiles at the end of the treatment, Hpylori eradication was assessed with 13C-urea breath test 4 wk after therapy. RESULTS: Sixty patients were enrolled including 28 males, and 20 patients in each group. The average age of the patients was 49.2 years, ranging from 18 to 84 years. H pylori eradication rates with per-protocol analysis were 82%, 89% and 90% in the three groups, respectively. Side effects were found in 11 patients, including mild dizziness, nausea, diarrhea and increased bowel movement. None of the 11 patients needed treatment for their side effects. CONCLUSION: One- or two-week furazolidone and amoxicillin-based quadruple rescue therapy with a low dose furazolidone (100 mg bid) for the eradication of Hpylori is effective. Extending the antibiotic course to 14 d could improve the eradication rates. 展开更多
关键词 Helicobacter pylori rescue therapy Quadruple therapy FURAZOLIDONE Low dose
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“Rescue” regimens after Helicobacter pylori treatment failure 被引量:21
20
作者 Javier P Gisbert 《World Journal of Gastroenterology》 SCIE CAS CSCD 2008年第35期5385-5402,共18页
Helicobacter pylori (H pylori) infection is the main cause of gastritis, gastroduodenal ulcer disease, and gastric cancer. After more than 20 years of experience in H pylori treatment, in my opinion, the ideal regimen... Helicobacter pylori (H pylori) infection is the main cause of gastritis, gastroduodenal ulcer disease, and gastric cancer. After more than 20 years of experience in H pylori treatment, in my opinion, the ideal regimen to treat this infection is still to be found. Currently, apart from having to know first-line eradication regimens well, we must also be prepared to face treatment failures. Therefore, in designing a treatment strategy we should not focus on the results of primary therapy alone, but also on the final (overall) eradication rate. The choice of a "rescue" treatment depends on which treatment is used initially. If a clarithromycin- based regimen was used initially, a subsequent metronidazole-based treatment (quadruple therapy) may be used afterwards, and then a levofloxacin- based combination would be a third "rescue" option. Alternatively, it has recently been suggested that levofloxacin-based rescue therapy constitutes an encouraging second-line strategy, representing an alternative to quadruple therapy in patients with previous PPI-clarithromycin-amoxicillin failure, with the advantage of efficacy, simplicity and safety. In this case, a quadruple regimen may be reserved as a third-line rescue option. Finally, rifabutin-based rescue therapy constitutes an encouraging empirical fourth- line strategy after multiple previous eradication failures with key antibiotics such as amoxicillin, clarithromycin, metronidazole, tetracycline, and levofloxacin. Even after two consecutive failures, several studies have demonstrated that H pylori eradication can finally be achieved in almost all patients if several rescue therapies are consecutively given. Therefore, the attitude in H pylori eradication therapy failure, evenafter two or more unsuccessful attempts, should be to fight and not to surrender. 展开更多
关键词 Helicobacter pylori rescue SALVAGE RIFABUTIN LEVOFLOXACIN
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