This comparative review explores the dynamic and evolving landscape of artificial intelligence(AI)-powered innovations within high-tech research and development(R&D).It delves into both theoreticalmodels and pract...This comparative review explores the dynamic and evolving landscape of artificial intelligence(AI)-powered innovations within high-tech research and development(R&D).It delves into both theoreticalmodels and practical applications across a broad range of industries,including biotechnology,automotive,aerospace,and telecom-munications.By examining critical advancements in AI algorithms,machine learning,deep learning models,simulations,and predictive analytics,the review underscores the transformative role AI has played in advancing theoretical research and shaping cutting-edge technologies.The review integrates both qualitative and quantitative data derived from academic studies,industry reports,and real-world case studies to showcase the tangible impacts of AI on product innovation,process optimization,and strategic decision-making.Notably,it discusses the challenges of integrating AI within complex industrial systems,such as ethical concerns,technical limitations,and the need for regulatory oversight.The findings reveal a mixed landscape where AI has significantly accelerated R&D processes,reduced costs,and enabled more precise simulations and predictions,but also highlighted gaps in knowledge transfer,skills adaptation,and cross-industry standardization.By bridging the gap between AI theory and practice,the review offers insights into the effectiveness,successes,and obstacles faced by organizations as they implement AI-driven solutions.Concluding with a forward-looking perspective,the review identifies emerging trends,future challenges,and promising opportunities inAI-poweredR&D,such as the rise of autonomous systems,AI-driven drug discovery,and sustainable energy solutions.It offers a holistic understanding of how AI is shaping the future of technological innovation and provides actionable insights for researchers,engineers,and policymakers involved in high-tech Research and Development(R&D).展开更多
With the acceleration of economic development and globalization and the rapid development of China’s foreign economy,the position of English education in higher vocational education has become increasingly prominent....With the acceleration of economic development and globalization and the rapid development of China’s foreign economy,the position of English education in higher vocational education has become increasingly prominent.Particularly in the multi-ethnic and multi-cultural areas of Guangxi Zhuang Autonomous Region,higher vocational education undertakes the responsibility of talent export for the construction of the China-ASEAN foreign trade exchange platform.However,the current phenomena and problems existing in higher vocational English education in Guangxi need to be deeply discussed and solved.Therefore,this paper discusses the development ideas of English education mode in Guangxi higher vocational education and studies the feasibility suggestions,in order to provide a reference for the future development of higher vocational English education in Guangxi.展开更多
Purpose:The goal of this study is to analyze the relationship between funded and unfunded papers and their citations in both basic and applied sciences.Design/methodology/approach:A power law model analyzes the relati...Purpose:The goal of this study is to analyze the relationship between funded and unfunded papers and their citations in both basic and applied sciences.Design/methodology/approach:A power law model analyzes the relationship between research funding and citations of papers using 831,337 documents recorded in the Web of Science database.Findings:The original results reveal general characteristics of the diffusion of science in research fields:a)Funded articles receive higher citations compared to unfunded papers in journals;b)Funded articles exhibit a super-linear growth in citations,surpassing the increase seen in unfunded articles.This finding reveals a higher diffusion of scientific knowledge in funded articles.Moreover,c)funded articles in both basic and applied sciences demonstrate a similar expected change in citations,equivalent to about 1.23%,when the number of funded papers increases by 1%in journals.This result suggests,for the first time,that funding effect of scientific research is an invariant driver,irrespective of the nature of the basic or applied sciences.Originality/value:This evidence suggests empirical laws of funding for scientific citations that explain the importance of robust funding mechanisms for achieving impactful research outcomes in science and society.These findings here also highlight that funding for scientific research is a critical driving force in supporting citations and the dissemination of scientific knowledge in recorded documents in both basic and applied sciences.Practical implications:This comprehensive result provides a holistic view of the relationship between funding and citation performance in science to guide policymakers and R&D managers with science policies by directing funding to research in promoting the scientific development and higher diffusion of results for the progress of human society.展开更多
Interdisciplinary research plays a crucial role in addressing complex problems by integrating knowledge from multiple disciplines.This integration fosters innovative solutions and enhances understanding across various...Interdisciplinary research plays a crucial role in addressing complex problems by integrating knowledge from multiple disciplines.This integration fosters innovative solutions and enhances understanding across various fields.This study explores the historical and sociological development of interdisciplinary research and maps its evolution through three distinct phases:pre-disciplinary,disciplinary,and post-disciplinary.It identifies key internal dynamics,such as disciplinary diversification,reorganization,and innovation,as primary drivers of this evolution.Additionally,this study highlights how external factors,particularly the urgency of World War II and the subsequent political and economic changes,have accelerated its advancement.The rise of interdisciplinary research has significantly reshaped traditional educational paradigms,promoting its integration across different educational levels.However,the inherent contradictions within interdisciplinary research present cognitive,emotional,and institutional challenges for researchers.Meanwhile,finding a balance between the breadth and depth of knowledge remains a critical challenge in interdisciplinary education.展开更多
As the railway sector intensifies its efforts in the technology research,system R&D and technology application of 5G-R,the paper conducts a preliminary study on its application frequency in terms of its frequency ...As the railway sector intensifies its efforts in the technology research,system R&D and technology application of 5G-R,the paper conducts a preliminary study on its application frequency in terms of its frequency propagation,network carrying capacity,its ability to work as industrial pillar,system applicability,and the compatibility of 5G-R with other systems.In line with China's GSM-R application practice and the application needs,the paper focuses on the study of key technologies such as model alignment of base station equipment,and optimization of 5G-R terminal and core network,identifying the priorities for the China's efforts to develop 5G-R and providing references for the research and application of related technologies.展开更多
Since 1990,China has made considerable progress in resolving the problem of“treatment difficulty”of cardiovascular diseases(CVD).The prevalent unhealthy lifestyle among Chinese residents has exposed a massive propor...Since 1990,China has made considerable progress in resolving the problem of“treatment difficulty”of cardiovascular diseases(CVD).The prevalent unhealthy lifestyle among Chinese residents has exposed a massive proportion of the population to CVD risk factors,and this situation is further worsened due to the accelerated aging population in China.CVD remains one of the greatest threats to the health of Chinese residents.In terms of the proportions of disease mortality among urban and rural residents in China,CVD has persistently ranked first.In 2021,CVD accounted for 48.98%and 47.35%of deaths in rural and urban areas,respectively.Two out of every five deaths can be attributed to CVD.To implement a national policy“focusing on the primary health institute and emphasizing prevention”and truly achieve a shift of CVD prevention and treatment from hospitals to communities,the National Center for Cardiovascular Diseases has organized experts from relevant fields across China to compile the“Report on Cardiovascular Health and Diseases in China”annually since 2005.The 2024 report is established based on representative,published,and high-quality big-data research results from cross-sectional and cohort population epidemiological surveys,randomized controlled clinical trials,large sample registry studies,and typical community prevention and treatment cases,along with data from some projects undertaken by the National Center for Cardiovascular Diseases.These firsthand data not only enrich the content of the current report but also provide a more timely and comprehensive reflection of the status of CVD prevention and treatment in China.展开更多
Diabetic eye disease refers to a group of eye complications that occur in diabetic patients and include diabetic retinopathy, diabetic macular edema, diabetic cataracts, and diabetic glaucoma. However, the global epid...Diabetic eye disease refers to a group of eye complications that occur in diabetic patients and include diabetic retinopathy, diabetic macular edema, diabetic cataracts, and diabetic glaucoma. However, the global epidemiology of these conditions has not been well characterized. In this study, we collected information on diabetic eye disease-related research grants from seven representative countries––the United States, China, Japan, the United Kingdom, Spain, Germany, and France––by searching for all global diabetic eye disease journal articles in the Web of Science and Pub Med databases, all global registered clinical trials in the Clinical Trials database, and new drugs approved by the United States, China, Japan, and EU agencies from 2012 to 2021. During this time period, diabetic retinopathy accounted for the vast majority(89.53%) of the 2288 government research grants that were funded to investigate diabetic eye disease, followed by diabetic macular edema(9.27%). The United States granted the most research funding for diabetic eye disease out of the seven countries assessed. The research objectives of grants focusing on diabetic retinopathy and diabetic macular edema differed by country. Additionally, the United States was dominant in terms of research output, publishing 17.53% of global papers about diabetic eye disease and receiving 22.58% of total citations. The United States and the United Kingdom led international collaborations in research into diabetic eye disease. Of the 415 clinical trials that we identified, diabetic macular edema was the major disease that was targeted for drug development(58.19%). Approximately half of the trials(49.13%) pertained to angiogenesis. However, few drugs were approved for ophthalmic(40 out of 1830;2.19%) and diabetic eye disease(3 out of 1830;0.02%) applications. Our findings show that basic and translational research related to diabetic eye disease in the past decade has not been highly active, and has yielded few new treatment methods and newly approved drugs.展开更多
Mid-deep geothermal reinjection technology is crucial for the sustainable development of geothermal resources,which has garnered significant attention and rapid growth in recent years.Currently,various geothermal rein...Mid-deep geothermal reinjection technology is crucial for the sustainable development of geothermal resources,which has garnered significant attention and rapid growth in recent years.Currently,various geothermal reinjection technologies lag behind,lacking effective integration to address issues like low reinjection rates and thermal breakthrough.This paper reviews the basic principles and development history of mid-deep geothermal reinjection technology,focusing on various technical methods used in the process and analyzing their applicability,advantages,and disadvantages under different geological conditions.It highlights the unique challenges posed by deep geothermal resources,including high temperature,high pressure,high stress,chemical corrosion,and complex geological structures.Additionally,it addresses challenges in equipment selection and durability,system stability and operation safety,environmental impact,and sustainable development.Finally,the paper explores future directions for mid-deep geothermal reinjection technology,highlighting key areas for further research and potential pathways for technological innovation.This comprehensive analysis aims to accelerate the advancement of geothermal reinjection technology,offering essential guidance for the efficient reinjection and sustainable development of geothermal resources.展开更多
Objective To identify the critical risks in the process of innovative drug research and development,and to provide reference for improving the efficiency of innovative drug development and risk control in China.Method...Objective To identify the critical risks in the process of innovative drug research and development,and to provide reference for improving the efficiency of innovative drug development and risk control in China.Methods Expert investigation and analytic hierarchy process were used to determine the weights of different risks.Results and Conclusion The research and analysis results showed that the risks at different stages of development had different effects on the success rate of drug development,among which the risk at the drug discovery stage influenced the most.In the drug discovery stage,inappropriate target selection had the greatest impact on the success rate of drug development.The lack of appropriate cell tissue or animal models had the greatest impact on the success rate of drug development from the discovery of a compound to the application for clinical trials.The difference in changes between nonclinical and clinical studies had the greatest impact on the success rate of drug development from early clinical studies to pivotal clinical studies.Incorrect dose selection had the greatest impact on the success rate of drug development from pivotal clinical studies to marketing authorization applications.The biggest impact from the marketing authorization application to the approval stage was inadequate communication with regulators.After investigating the weight of risk factors in the process of innovative drug development based on scientific methods,a new perspective for the risk control of new drug development and improving the research and development efficiency is provided.展开更多
Promoting agricultural modernisation through technological change is an important strategy for China.China's carbon neutrality strategy is leading to systemic socio-economic changes that could exacerbate the uncer...Promoting agricultural modernisation through technological change is an important strategy for China.China's carbon neutrality strategy is leading to systemic socio-economic changes that could exacerbate the uncertainty of agricultural development.Therefore,applying a computable general equilibrium(CGE)model,this study characterises the agricultural sector in detail,introducing endogenous technological change proxied by research and development(R&D)to assess the impact of different technological change scenarios on agricultural development under the carbon neutrality target.The results show that allocating carbon revenue for R&D inputs can mitigate the significant negative impact of achieving carbon neutrality on knowledge capital and production in agricultural sectors.Overall,using carbon revenue only for R&D input in crop sectors has the optimal effect on increasing the agricultural sectors'knowledge capital,improving crop production and profit,reducing crop external dependence and promoting the synergistic reduction of carbon and pollutant emissions.However,this scenario has the largest negative impact on macro-economics and household welfare.In contrast,allocating carbon revenue to promote technological change in broader non-energy sectors or both crops and non-energy sectors can effectively mitigate negative socio-economic impacts,but the positive impact on agricultural development is minimal.These findings provide practical insights for the rational use of carbon revenue to expand agricultural R&D investment and ensure balanced agricultural and economic development under the carbon neutrality target.展开更多
The recent progress on the proteins in edible insects was summarized, in- cluding the nutritional value, healthy value, food safety, extraction and content mea- surement of the proteins in edible insects, as well as t...The recent progress on the proteins in edible insects was summarized, in- cluding the nutritional value, healthy value, food safety, extraction and content mea- surement of the proteins in edible insects, as well as the main development direc- tion of edible insect proteins. And we also pointed out the bottlenecks that restricted the development and utilization of proteins in edible insects, and proposed the prospect of the research, development and utilization of edible insects proteins.展开更多
Purpose–This method will become a new development trend in subgrade structure design for high speed railways.Design/methodology/approach–This paper summarizes the structural types and design methods of subgrade bed ...Purpose–This method will become a new development trend in subgrade structure design for high speed railways.Design/methodology/approach–This paper summarizes the structural types and design methods of subgrade bed for high speed railways in China,Japan,France,Germany,the United States and other countries based on the study and analysis of existing literature and combined with the research results and practices of high speed railway subgrade engineering at home and abroad.Findings–It is found that in foreign countries,the layered reinforced structure is generally adopted for the subgrade bed of high speed railways,and the unified double-layer or multi-layer structure is adopted for the surface layer of subgrade bed,while the simple structure is adopted in China;in foreign countries,different inspection parameters are adopted to evaluate the compaction state of fillers according to their respective understanding and practice,while in China,compaction coefficient,subsoil coefficient and dynamic deformation modulus are adopted for such evaluation;in foreign countries,the subgrade top deformation control method,the subgrade bottom deformation control method,the subsurface fill strength control method are mainly adopted in subgrade bed structure design of high speed railways,while in China,dynamic deformation control of subgrade surface and dynamic strain control of subgrade bed bottom layer is adopted in the design.However,the cumulative deformation of subgrade caused by train cyclic vibration load is not considered in the existing design methods.Originality/value–This paper introduces a new subgrade structure design method based on whole-process dynamics analysis that meets subgrade functional requirements and is established on the basis of the existing research at home and abroad on prediction methods for cumulative deformation of subgrade soil.展开更多
Targeting modernization, we should keep to the Chinese-style path of car- rying out industrialization in a new way and advancing IT application, urbanization, and agricultural modernization. In the research, the scien...Targeting modernization, we should keep to the Chinese-style path of car- rying out industrialization in a new way and advancing IT application, urbanization, and agricultural modernization. In the research, the scientific concepts of IT applica- tion, urbanization, agricultural modernization and industrialization were illustrated and the interrelations were analyzed, with measures on harmonized development pro- posed based on existing problems.展开更多
Objective To systematically analyze the current development status of biopharmaceutical industrial park in China,sort out the problems and put forward some countermeasures and suggestions.Methods Relevant literature w...Objective To systematically analyze the current development status of biopharmaceutical industrial park in China,sort out the problems and put forward some countermeasures and suggestions.Methods Relevant literature was searched and reviewed to find out the problems faced by the development of biopharmaceutical industrial parks in China.Results and Conclusion Biopharmaceutical industrial parks are developing rapidly due to their unique industrial clustering advantages,but there are problems such as lack of overall planning at the top level,insufficient government support,imperfect talent support services and weak innovation capacity of the parks.It is recommended to promote the rapid development of biopharmaceutical industrial parks and biopharmaceutical enterprises by strengthening top-level design,increasing government support,focusing on talent introduction,and enhancing the innovative strength of the parks.展开更多
1.Introduction Surface integrity has great significance for the quality and performance of machined components,and has therefore been increasingly recognized by industry.In particular,within certain industries that re...1.Introduction Surface integrity has great significance for the quality and performance of machined components,and has therefore been increasingly recognized by industry.In particular,within certain industries that require high reliability,such as the aerospace industry,surface integrity is one of the most relevant indexes used to evaluate the quality of machined parts.Thus,obtaining updated knowledge on surface integrity is of great interest to both the academic community and industry[1].展开更多
Some of the progress made in our laboratories in collaboration with industry in research and development work on high performance oxide-nonoxide composites for metallurgical applications has been reviewed. (1) SiAlO...Some of the progress made in our laboratories in collaboration with industry in research and development work on high performance oxide-nonoxide composites for metallurgical applications has been reviewed. (1) SiAlON bonded corundum composites for blast furnace usage have been produced by reduction-nitridation sinte-ring at high temperature, using bauxite instead of alu-mina in the matrix. (2) Low carbon Al2O3 - SiAlON slide plate materials successfully used in high quality steel continuous casting have been developed in which most or all of the graphite in Al2O3 - C brick is replaced by bauxite-based β-SiAlON. (3) A1/Si metal bonded A12 03 - C material characterized by low carbon content, low firing temperature and in-situ formation of carbides and nitrides at high temperature during service are found to possess very high hot strength and very good thermal shock resistance and have also been successfully used as slide plates in ladles and tundishes for high quality steel casting.展开更多
Inspired by successful development of shale gas in USA and influenced by hydrocarbon resources shortage currently, China has strengthened shale gas research and accelerated its exploration process. In order to enrich ...Inspired by successful development of shale gas in USA and influenced by hydrocarbon resources shortage currently, China has strengthened shale gas research and accelerated its exploration process. In order to enrich coalbed methane (CBM) and shale gas geological theory and promote their development process, this paper compared shale gas with CBM in accumulation, distribution, reservoir and production. It expatiated on the background and significance of the combined research and development, and analyzed the geological foundation and future prospects. Our investigation demonstrated that there are many sets of coal-bearing strata in Shanxi formation of Permian system in Ordos in North China, Longtan formation of Upper Permian and Xujiahe formation of Upper Triassic in Southern Yangtze region, Xishanyao formation of Middle Jurassic in Turpan-Hami Basin and Junggar Basin in Northwest China, and Shahezi formation of Cretaceous in Songliao Basin in northeast China. In these regions, shales which are interbeded with coal seams have the characters of big thickness, continuous distribution, high content of organic matter, good parent material and high maturity, accord with the basic geological conditions to format shale gas and CBM reservoir and composite gas reservoir, thus form appropriate regions and layers to carry out joint research and exploration with good prospects for development.展开更多
Baoshan Iron & Steel Co.,Ltd., (referred to as Baosteel) in China first succeeded in developing the U-ing-O- ing-Expanding (UOE) longitudinal submerged arc welded pipes (SAWLs) offshore linepipe of a maximum th...Baoshan Iron & Steel Co.,Ltd., (referred to as Baosteel) in China first succeeded in developing the U-ing-O- ing-Expanding (UOE) longitudinal submerged arc welded pipes (SAWLs) offshore linepipe of a maximum thickness/ outside diameter (T/D) 0.042 in 2011. Described in this paper is the research and development of the X70 UOE SAWL pipes by the company. The result shows that the said X70 linepipe has been in compliance with relevant requirements as specified in Specifications DNV-OS-F101 ,and has been successfully used in the South China Sea deepwater gas pipeline project.展开更多
The topic was concentrated on environmental technology development in China within the context of China's economic acceleration and reform. Firstly, cleaner technology should be adopted where possible in indu...The topic was concentrated on environmental technology development in China within the context of China's economic acceleration and reform. Firstly, cleaner technology should be adopted where possible in industrial production; secondly, eco agricultural technological system, especially biological technology, should be developed in agricultural production; thirdly, end of pipe solution should focus on waste utilization or recycling technology where appropriate clean technology does not exist; lastly but not the least, existing technologies to minimize eco environmental deterioration such as soil erosion, salinization, desertification and deforestation should also be extended and developed. The mentioned ways of environmental technology development can only be realized on the condition that a resource conservation based production system and life style could be established and appropriate policy secured.展开更多
Due to the restrictions on the conditions for afforestation and sand control,the development research,and application of sand barriers have accelerated in recent years,but some problems that cannot be ignored have eme...Due to the restrictions on the conditions for afforestation and sand control,the development research,and application of sand barriers have accelerated in recent years,but some problems that cannot be ignored have emerged in practice. In this paper,the functions of wind prevention,sand blocking and fixation,improving soil physical and chemical properties and increasing plant diversity of sand barriers,accretion coefficient and capacity between sand barriers,and mobile sand barriers were analyzed firstly,and then several issues that should be noted in the development and application of sand barriers were proposed. The results show that sand barriers can fix sand on the spot and maintain the stability of sand surface. As an auxiliary measure before afforestation on a mobile sand surface,they are practical and feasible. The biggest drawback of sand barriers is that they are easy to be saturated. Although they can increase plant diversity and surface roughness,they lose the function of blocking sand flow after being saturated,and their function of in-situ sand fixation also rapidly decreases with the degradation of sand barriers. Mobile sand barriers overcome the disadvantage of sand barriers being easy to be saturated to some extent,but the cost greatly increases. In terms of desertification prevention and control by plants,plants are used as sand barriers to study their functions of sand blocking and sand fixation in many researches and practices,but the more important ecological functions of adjusting temperature on sand surface and achieving surface thermodynamic equilibrium of plants are ignored.展开更多
文摘This comparative review explores the dynamic and evolving landscape of artificial intelligence(AI)-powered innovations within high-tech research and development(R&D).It delves into both theoreticalmodels and practical applications across a broad range of industries,including biotechnology,automotive,aerospace,and telecom-munications.By examining critical advancements in AI algorithms,machine learning,deep learning models,simulations,and predictive analytics,the review underscores the transformative role AI has played in advancing theoretical research and shaping cutting-edge technologies.The review integrates both qualitative and quantitative data derived from academic studies,industry reports,and real-world case studies to showcase the tangible impacts of AI on product innovation,process optimization,and strategic decision-making.Notably,it discusses the challenges of integrating AI within complex industrial systems,such as ethical concerns,technical limitations,and the need for regulatory oversight.The findings reveal a mixed landscape where AI has significantly accelerated R&D processes,reduced costs,and enabled more precise simulations and predictions,but also highlighted gaps in knowledge transfer,skills adaptation,and cross-industry standardization.By bridging the gap between AI theory and practice,the review offers insights into the effectiveness,successes,and obstacles faced by organizations as they implement AI-driven solutions.Concluding with a forward-looking perspective,the review identifies emerging trends,future challenges,and promising opportunities inAI-poweredR&D,such as the rise of autonomous systems,AI-driven drug discovery,and sustainable energy solutions.It offers a holistic understanding of how AI is shaping the future of technological innovation and provides actionable insights for researchers,engineers,and policymakers involved in high-tech Research and Development(R&D).
基金2022 Guangxi Education Science Planning Project“The Inheritance and Discussion of National Culture in the Internationalization of Higher Vocational Education under the Background of the New Era”(2022ZJY3095)。
文摘With the acceleration of economic development and globalization and the rapid development of China’s foreign economy,the position of English education in higher vocational education has become increasingly prominent.Particularly in the multi-ethnic and multi-cultural areas of Guangxi Zhuang Autonomous Region,higher vocational education undertakes the responsibility of talent export for the construction of the China-ASEAN foreign trade exchange platform.However,the current phenomena and problems existing in higher vocational English education in Guangxi need to be deeply discussed and solved.Therefore,this paper discusses the development ideas of English education mode in Guangxi higher vocational education and studies the feasibility suggestions,in order to provide a reference for the future development of higher vocational English education in Guangxi.
文摘Purpose:The goal of this study is to analyze the relationship between funded and unfunded papers and their citations in both basic and applied sciences.Design/methodology/approach:A power law model analyzes the relationship between research funding and citations of papers using 831,337 documents recorded in the Web of Science database.Findings:The original results reveal general characteristics of the diffusion of science in research fields:a)Funded articles receive higher citations compared to unfunded papers in journals;b)Funded articles exhibit a super-linear growth in citations,surpassing the increase seen in unfunded articles.This finding reveals a higher diffusion of scientific knowledge in funded articles.Moreover,c)funded articles in both basic and applied sciences demonstrate a similar expected change in citations,equivalent to about 1.23%,when the number of funded papers increases by 1%in journals.This result suggests,for the first time,that funding effect of scientific research is an invariant driver,irrespective of the nature of the basic or applied sciences.Originality/value:This evidence suggests empirical laws of funding for scientific citations that explain the importance of robust funding mechanisms for achieving impactful research outcomes in science and society.These findings here also highlight that funding for scientific research is a critical driving force in supporting citations and the dissemination of scientific knowledge in recorded documents in both basic and applied sciences.Practical implications:This comprehensive result provides a holistic view of the relationship between funding and citation performance in science to guide policymakers and R&D managers with science policies by directing funding to research in promoting the scientific development and higher diffusion of results for the progress of human society.
基金funded by the National Natural Science Foundation of China for Young Scholars(No.72304019)Peking University Health Science Center Project(No.2023YB46)+1 种基金the National Natural Science Foundation of China for Special Purpose(No.J2124013)the ISTIC-Clarivate Joint Laboratory for Scientometrics(No.IT2319).
文摘Interdisciplinary research plays a crucial role in addressing complex problems by integrating knowledge from multiple disciplines.This integration fosters innovative solutions and enhances understanding across various fields.This study explores the historical and sociological development of interdisciplinary research and maps its evolution through three distinct phases:pre-disciplinary,disciplinary,and post-disciplinary.It identifies key internal dynamics,such as disciplinary diversification,reorganization,and innovation,as primary drivers of this evolution.Additionally,this study highlights how external factors,particularly the urgency of World War II and the subsequent political and economic changes,have accelerated its advancement.The rise of interdisciplinary research has significantly reshaped traditional educational paradigms,promoting its integration across different educational levels.However,the inherent contradictions within interdisciplinary research present cognitive,emotional,and institutional challenges for researchers.Meanwhile,finding a balance between the breadth and depth of knowledge remains a critical challenge in interdisciplinary education.
文摘As the railway sector intensifies its efforts in the technology research,system R&D and technology application of 5G-R,the paper conducts a preliminary study on its application frequency in terms of its frequency propagation,network carrying capacity,its ability to work as industrial pillar,system applicability,and the compatibility of 5G-R with other systems.In line with China's GSM-R application practice and the application needs,the paper focuses on the study of key technologies such as model alignment of base station equipment,and optimization of 5G-R terminal and core network,identifying the priorities for the China's efforts to develop 5G-R and providing references for the research and application of related technologies.
文摘Since 1990,China has made considerable progress in resolving the problem of“treatment difficulty”of cardiovascular diseases(CVD).The prevalent unhealthy lifestyle among Chinese residents has exposed a massive proportion of the population to CVD risk factors,and this situation is further worsened due to the accelerated aging population in China.CVD remains one of the greatest threats to the health of Chinese residents.In terms of the proportions of disease mortality among urban and rural residents in China,CVD has persistently ranked first.In 2021,CVD accounted for 48.98%and 47.35%of deaths in rural and urban areas,respectively.Two out of every five deaths can be attributed to CVD.To implement a national policy“focusing on the primary health institute and emphasizing prevention”and truly achieve a shift of CVD prevention and treatment from hospitals to communities,the National Center for Cardiovascular Diseases has organized experts from relevant fields across China to compile the“Report on Cardiovascular Health and Diseases in China”annually since 2005.The 2024 report is established based on representative,published,and high-quality big-data research results from cross-sectional and cohort population epidemiological surveys,randomized controlled clinical trials,large sample registry studies,and typical community prevention and treatment cases,along with data from some projects undertaken by the National Center for Cardiovascular Diseases.These firsthand data not only enrich the content of the current report but also provide a more timely and comprehensive reflection of the status of CVD prevention and treatment in China.
基金supported by the National Natural Science Foundation of China,No.82122009 (to JX)Science Research Foundation ofAier Eye Hospital Group,No.AM2001D1 (to JX)the Natural Science Foundation of Hunan Province,No.2020JJ5002 (to SJ)。
文摘Diabetic eye disease refers to a group of eye complications that occur in diabetic patients and include diabetic retinopathy, diabetic macular edema, diabetic cataracts, and diabetic glaucoma. However, the global epidemiology of these conditions has not been well characterized. In this study, we collected information on diabetic eye disease-related research grants from seven representative countries––the United States, China, Japan, the United Kingdom, Spain, Germany, and France––by searching for all global diabetic eye disease journal articles in the Web of Science and Pub Med databases, all global registered clinical trials in the Clinical Trials database, and new drugs approved by the United States, China, Japan, and EU agencies from 2012 to 2021. During this time period, diabetic retinopathy accounted for the vast majority(89.53%) of the 2288 government research grants that were funded to investigate diabetic eye disease, followed by diabetic macular edema(9.27%). The United States granted the most research funding for diabetic eye disease out of the seven countries assessed. The research objectives of grants focusing on diabetic retinopathy and diabetic macular edema differed by country. Additionally, the United States was dominant in terms of research output, publishing 17.53% of global papers about diabetic eye disease and receiving 22.58% of total citations. The United States and the United Kingdom led international collaborations in research into diabetic eye disease. Of the 415 clinical trials that we identified, diabetic macular edema was the major disease that was targeted for drug development(58.19%). Approximately half of the trials(49.13%) pertained to angiogenesis. However, few drugs were approved for ophthalmic(40 out of 1830;2.19%) and diabetic eye disease(3 out of 1830;0.02%) applications. Our findings show that basic and translational research related to diabetic eye disease in the past decade has not been highly active, and has yielded few new treatment methods and newly approved drugs.
基金funded by the National Nature Science Foundation of China(No.42272350)Hunan Provincial Key R&D Program(2022SK 2070)the Foundation of Shanxi Key Laboratory for Exploration and Exploitation of Geothermal Resources(No.SX202202).
文摘Mid-deep geothermal reinjection technology is crucial for the sustainable development of geothermal resources,which has garnered significant attention and rapid growth in recent years.Currently,various geothermal reinjection technologies lag behind,lacking effective integration to address issues like low reinjection rates and thermal breakthrough.This paper reviews the basic principles and development history of mid-deep geothermal reinjection technology,focusing on various technical methods used in the process and analyzing their applicability,advantages,and disadvantages under different geological conditions.It highlights the unique challenges posed by deep geothermal resources,including high temperature,high pressure,high stress,chemical corrosion,and complex geological structures.Additionally,it addresses challenges in equipment selection and durability,system stability and operation safety,environmental impact,and sustainable development.Finally,the paper explores future directions for mid-deep geothermal reinjection technology,highlighting key areas for further research and potential pathways for technological innovation.This comprehensive analysis aims to accelerate the advancement of geothermal reinjection technology,offering essential guidance for the efficient reinjection and sustainable development of geothermal resources.
文摘Objective To identify the critical risks in the process of innovative drug research and development,and to provide reference for improving the efficiency of innovative drug development and risk control in China.Methods Expert investigation and analytic hierarchy process were used to determine the weights of different risks.Results and Conclusion The research and analysis results showed that the risks at different stages of development had different effects on the success rate of drug development,among which the risk at the drug discovery stage influenced the most.In the drug discovery stage,inappropriate target selection had the greatest impact on the success rate of drug development.The lack of appropriate cell tissue or animal models had the greatest impact on the success rate of drug development from the discovery of a compound to the application for clinical trials.The difference in changes between nonclinical and clinical studies had the greatest impact on the success rate of drug development from early clinical studies to pivotal clinical studies.Incorrect dose selection had the greatest impact on the success rate of drug development from pivotal clinical studies to marketing authorization applications.The biggest impact from the marketing authorization application to the approval stage was inadequate communication with regulators.After investigating the weight of risk factors in the process of innovative drug development based on scientific methods,a new perspective for the risk control of new drug development and improving the research and development efficiency is provided.
基金supported by the National Natural Science Foundation of China[Grant No.72204234,72074022]the National Social Science Foundation of China[Grant No.22AZD094]the project for Carbon Neutral General Knowledge Course Construction of China University of Geosciences.
文摘Promoting agricultural modernisation through technological change is an important strategy for China.China's carbon neutrality strategy is leading to systemic socio-economic changes that could exacerbate the uncertainty of agricultural development.Therefore,applying a computable general equilibrium(CGE)model,this study characterises the agricultural sector in detail,introducing endogenous technological change proxied by research and development(R&D)to assess the impact of different technological change scenarios on agricultural development under the carbon neutrality target.The results show that allocating carbon revenue for R&D inputs can mitigate the significant negative impact of achieving carbon neutrality on knowledge capital and production in agricultural sectors.Overall,using carbon revenue only for R&D input in crop sectors has the optimal effect on increasing the agricultural sectors'knowledge capital,improving crop production and profit,reducing crop external dependence and promoting the synergistic reduction of carbon and pollutant emissions.However,this scenario has the largest negative impact on macro-economics and household welfare.In contrast,allocating carbon revenue to promote technological change in broader non-energy sectors or both crops and non-energy sectors can effectively mitigate negative socio-economic impacts,but the positive impact on agricultural development is minimal.These findings provide practical insights for the rational use of carbon revenue to expand agricultural R&D investment and ensure balanced agricultural and economic development under the carbon neutrality target.
基金Supported by the Special Fund for Agro-scientific Research in the Public Interest(200904025)the Natural Science Foundation of Beijing(6122024)+1 种基金the Surface Project of the Science and Technology Development Program of Beijing Municipal Education Commission(KM200900005002)the Project for the Agricultural Science and Technology of Beijing(20110115)~~
文摘The recent progress on the proteins in edible insects was summarized, in- cluding the nutritional value, healthy value, food safety, extraction and content mea- surement of the proteins in edible insects, as well as the main development direc- tion of edible insect proteins. And we also pointed out the bottlenecks that restricted the development and utilization of proteins in edible insects, and proposed the prospect of the research, development and utilization of edible insects proteins.
基金The research was supported by the National Natural Science Foundation of China(Grant Nos.41731288 and 41972299)the Science and Technology Research and Development Program of China Railway(Grant No.P2018G050)+1 种基金the Young Top-Notch Talent Project of National“Ten Thousands Talent Program”(Grant No.2019YJ300)the Major Scientific Research and Development Project of China Academy of Railway Sciences Corporation Limited(Grant No.2019YJ026).
文摘Purpose–This method will become a new development trend in subgrade structure design for high speed railways.Design/methodology/approach–This paper summarizes the structural types and design methods of subgrade bed for high speed railways in China,Japan,France,Germany,the United States and other countries based on the study and analysis of existing literature and combined with the research results and practices of high speed railway subgrade engineering at home and abroad.Findings–It is found that in foreign countries,the layered reinforced structure is generally adopted for the subgrade bed of high speed railways,and the unified double-layer or multi-layer structure is adopted for the surface layer of subgrade bed,while the simple structure is adopted in China;in foreign countries,different inspection parameters are adopted to evaluate the compaction state of fillers according to their respective understanding and practice,while in China,compaction coefficient,subsoil coefficient and dynamic deformation modulus are adopted for such evaluation;in foreign countries,the subgrade top deformation control method,the subgrade bottom deformation control method,the subsurface fill strength control method are mainly adopted in subgrade bed structure design of high speed railways,while in China,dynamic deformation control of subgrade surface and dynamic strain control of subgrade bed bottom layer is adopted in the design.However,the cumulative deformation of subgrade caused by train cyclic vibration load is not considered in the existing design methods.Originality/value–This paper introduces a new subgrade structure design method based on whole-process dynamics analysis that meets subgrade functional requirements and is established on the basis of the existing research at home and abroad on prediction methods for cumulative deformation of subgrade soil.
文摘Targeting modernization, we should keep to the Chinese-style path of car- rying out industrialization in a new way and advancing IT application, urbanization, and agricultural modernization. In the research, the scientific concepts of IT applica- tion, urbanization, agricultural modernization and industrialization were illustrated and the interrelations were analyzed, with measures on harmonized development pro- posed based on existing problems.
文摘Objective To systematically analyze the current development status of biopharmaceutical industrial park in China,sort out the problems and put forward some countermeasures and suggestions.Methods Relevant literature was searched and reviewed to find out the problems faced by the development of biopharmaceutical industrial parks in China.Results and Conclusion Biopharmaceutical industrial parks are developing rapidly due to their unique industrial clustering advantages,but there are problems such as lack of overall planning at the top level,insufficient government support,imperfect talent support services and weak innovation capacity of the parks.It is recommended to promote the rapid development of biopharmaceutical industrial parks and biopharmaceutical enterprises by strengthening top-level design,increasing government support,focusing on talent introduction,and enhancing the innovative strength of the parks.
文摘1.Introduction Surface integrity has great significance for the quality and performance of machined components,and has therefore been increasingly recognized by industry.In particular,within certain industries that require high reliability,such as the aerospace industry,surface integrity is one of the most relevant indexes used to evaluate the quality of machined parts.Thus,obtaining updated knowledge on surface integrity is of great interest to both the academic community and industry[1].
文摘Some of the progress made in our laboratories in collaboration with industry in research and development work on high performance oxide-nonoxide composites for metallurgical applications has been reviewed. (1) SiAlON bonded corundum composites for blast furnace usage have been produced by reduction-nitridation sinte-ring at high temperature, using bauxite instead of alu-mina in the matrix. (2) Low carbon Al2O3 - SiAlON slide plate materials successfully used in high quality steel continuous casting have been developed in which most or all of the graphite in Al2O3 - C brick is replaced by bauxite-based β-SiAlON. (3) A1/Si metal bonded A12 03 - C material characterized by low carbon content, low firing temperature and in-situ formation of carbides and nitrides at high temperature during service are found to possess very high hot strength and very good thermal shock resistance and have also been successfully used as slide plates in ladles and tundishes for high quality steel casting.
文摘Inspired by successful development of shale gas in USA and influenced by hydrocarbon resources shortage currently, China has strengthened shale gas research and accelerated its exploration process. In order to enrich coalbed methane (CBM) and shale gas geological theory and promote their development process, this paper compared shale gas with CBM in accumulation, distribution, reservoir and production. It expatiated on the background and significance of the combined research and development, and analyzed the geological foundation and future prospects. Our investigation demonstrated that there are many sets of coal-bearing strata in Shanxi formation of Permian system in Ordos in North China, Longtan formation of Upper Permian and Xujiahe formation of Upper Triassic in Southern Yangtze region, Xishanyao formation of Middle Jurassic in Turpan-Hami Basin and Junggar Basin in Northwest China, and Shahezi formation of Cretaceous in Songliao Basin in northeast China. In these regions, shales which are interbeded with coal seams have the characters of big thickness, continuous distribution, high content of organic matter, good parent material and high maturity, accord with the basic geological conditions to format shale gas and CBM reservoir and composite gas reservoir, thus form appropriate regions and layers to carry out joint research and exploration with good prospects for development.
文摘Baoshan Iron & Steel Co.,Ltd., (referred to as Baosteel) in China first succeeded in developing the U-ing-O- ing-Expanding (UOE) longitudinal submerged arc welded pipes (SAWLs) offshore linepipe of a maximum thickness/ outside diameter (T/D) 0.042 in 2011. Described in this paper is the research and development of the X70 UOE SAWL pipes by the company. The result shows that the said X70 linepipe has been in compliance with relevant requirements as specified in Specifications DNV-OS-F101 ,and has been successfully used in the South China Sea deepwater gas pipeline project.
文摘The topic was concentrated on environmental technology development in China within the context of China's economic acceleration and reform. Firstly, cleaner technology should be adopted where possible in industrial production; secondly, eco agricultural technological system, especially biological technology, should be developed in agricultural production; thirdly, end of pipe solution should focus on waste utilization or recycling technology where appropriate clean technology does not exist; lastly but not the least, existing technologies to minimize eco environmental deterioration such as soil erosion, salinization, desertification and deforestation should also be extended and developed. The mentioned ways of environmental technology development can only be realized on the condition that a resource conservation based production system and life style could be established and appropriate policy secured.
基金Supported by National Natural Science Foundation of China(41671528)
文摘Due to the restrictions on the conditions for afforestation and sand control,the development research,and application of sand barriers have accelerated in recent years,but some problems that cannot be ignored have emerged in practice. In this paper,the functions of wind prevention,sand blocking and fixation,improving soil physical and chemical properties and increasing plant diversity of sand barriers,accretion coefficient and capacity between sand barriers,and mobile sand barriers were analyzed firstly,and then several issues that should be noted in the development and application of sand barriers were proposed. The results show that sand barriers can fix sand on the spot and maintain the stability of sand surface. As an auxiliary measure before afforestation on a mobile sand surface,they are practical and feasible. The biggest drawback of sand barriers is that they are easy to be saturated. Although they can increase plant diversity and surface roughness,they lose the function of blocking sand flow after being saturated,and their function of in-situ sand fixation also rapidly decreases with the degradation of sand barriers. Mobile sand barriers overcome the disadvantage of sand barriers being easy to be saturated to some extent,but the cost greatly increases. In terms of desertification prevention and control by plants,plants are used as sand barriers to study their functions of sand blocking and sand fixation in many researches and practices,but the more important ecological functions of adjusting temperature on sand surface and achieving surface thermodynamic equilibrium of plants are ignored.