Timer error as well as its convention is very important for dose accuracy during irradiation. This paper determines the timer error of irradiators at Secondary Standard Dosimetry Laboratory (SSDL) in Nigeria. The irra...Timer error as well as its convention is very important for dose accuracy during irradiation. This paper determines the timer error of irradiators at Secondary Standard Dosimetry Laboratory (SSDL) in Nigeria. The irradiators are Cs-137 OB6 irradiator and X-ray irradiators at the Protection level SSDL;and Co-60 irradiator at the Therapy Level SSDL. PTW UNIDOS electrometer and LS01 Ionization chamber were used at the Protection Level to obtain doses for both Cs-137 OB6 and X-ray irradiators while an IBA farmer type ionization chamber and an IBA DOSE 1 electrometer were used at the Protection Level SSDL. Single/multiple exposure method and graphical method were used in the determination of the timer error for the three irradiators. The timer error obtained for Cs-137 OB6 irradiator was 0.48 ± 0.01 s, the timer error for the X-ray irradiator was 0.09 ± 0.01 s while the timer error obtained for GammaBeam X200 was 1.21 ± 0.04 s. It was observed that the timer error is not affected by source to detector distance. It was also observed that the timer error of Co-60 Gamma X200 irradiator is increasing with the age of the machine. Source to detector distance and field size do not contribute towards the timer error of the irradiators. The timer error of the Co-60 Gamma X200 irradiator (the only irradiator among the irradiators with a pneumatic system) increases with the age of the irradiator.展开更多
Radiotherapy is the most widely applied oncologic treatment modality utilizing ionizing radiation. A high degree of accuracy, reliability and reproducibility is required for a successful treatment outcome. Measurement...Radiotherapy is the most widely applied oncologic treatment modality utilizing ionizing radiation. A high degree of accuracy, reliability and reproducibility is required for a successful treatment outcome. Measurement using ionization chamber is a prerequisite for absorbed dose determination for external beam radiotherapy. Calibration coefficient is expressed in terms of air kerma and absorbed dose to water traceable to Secondary Standards Dosimetry Laboratory. The objective of this work was to evaluate the level of accuracy of ionization chamber used for clinical radiotherapy beam determination. Measurement and accuracy determination were carried out according to IAEA TRS 398 protocol. Clinical farmers type ionization chamber measurement and National Reference standard from Secondary Standards Dosimetry Laboratory were both exposed to cobalt-60 beam and measurement results compared under the same environmental conditions. The accuracy level between National Reference Standard and clinical radiotherapy standard was found to be −1.92% and −2.02% for air kerma and absorbed dose to water respectively. To minimize the effect of error and maximize therapeutic dose during treatment in order to achieve required clinical outcome, calibration factor was determined for air kerma (Nk) as 49.7 mGy/nC and absorbed dose to water ND, as 52.9 mGy/nC. The study established that radiotherapy beam measurement chain is prone to errors. Hence there is a need to independently verify the accuracy of radiation dose to ensure precision of dose delivery. The errors must be accounted for during clinical planning by factoring in calibration factor to minimize the systematic errors during treatment, and thereby providing enough room to achieve ±5% dose delivery to tumor target as recommended by ICRU.展开更多
目的:对常用4种新型进口及国产医用诊断X射线剂量仪的能量响应特性进行比较研究。方法:在国际原子能机构(IAEA)北京二级标准剂量学实验室(SSDL)的标准辐射场中,采用替代法分别完成10种管电压为60~150 k V、管电流为10 m A、用2.5 mm Al...目的:对常用4种新型进口及国产医用诊断X射线剂量仪的能量响应特性进行比较研究。方法:在国际原子能机构(IAEA)北京二级标准剂量学实验室(SSDL)的标准辐射场中,采用替代法分别完成10种管电压为60~150 k V、管电流为10 m A、用2.5 mm Al(毫米铝)做附加过滤的X射线诊断辐射线质进行比对测量。结果:国产RD-98诊断剂量仪与进口剂量仪的能量响应性能,在60~150 k V的X射线范围内,不同能量对剂量的响应均在±5%以内。结论:4种新型诊断X射线剂量仪的能量响应特性均良好,半导体探测器的诊断剂量仪与空气电离室剂量仪,不同能量对剂量的响应均符合国际电工委员会(IEC)的要求。展开更多
文摘Timer error as well as its convention is very important for dose accuracy during irradiation. This paper determines the timer error of irradiators at Secondary Standard Dosimetry Laboratory (SSDL) in Nigeria. The irradiators are Cs-137 OB6 irradiator and X-ray irradiators at the Protection level SSDL;and Co-60 irradiator at the Therapy Level SSDL. PTW UNIDOS electrometer and LS01 Ionization chamber were used at the Protection Level to obtain doses for both Cs-137 OB6 and X-ray irradiators while an IBA farmer type ionization chamber and an IBA DOSE 1 electrometer were used at the Protection Level SSDL. Single/multiple exposure method and graphical method were used in the determination of the timer error for the three irradiators. The timer error obtained for Cs-137 OB6 irradiator was 0.48 ± 0.01 s, the timer error for the X-ray irradiator was 0.09 ± 0.01 s while the timer error obtained for GammaBeam X200 was 1.21 ± 0.04 s. It was observed that the timer error is not affected by source to detector distance. It was also observed that the timer error of Co-60 Gamma X200 irradiator is increasing with the age of the machine. Source to detector distance and field size do not contribute towards the timer error of the irradiators. The timer error of the Co-60 Gamma X200 irradiator (the only irradiator among the irradiators with a pneumatic system) increases with the age of the irradiator.
文摘Radiotherapy is the most widely applied oncologic treatment modality utilizing ionizing radiation. A high degree of accuracy, reliability and reproducibility is required for a successful treatment outcome. Measurement using ionization chamber is a prerequisite for absorbed dose determination for external beam radiotherapy. Calibration coefficient is expressed in terms of air kerma and absorbed dose to water traceable to Secondary Standards Dosimetry Laboratory. The objective of this work was to evaluate the level of accuracy of ionization chamber used for clinical radiotherapy beam determination. Measurement and accuracy determination were carried out according to IAEA TRS 398 protocol. Clinical farmers type ionization chamber measurement and National Reference standard from Secondary Standards Dosimetry Laboratory were both exposed to cobalt-60 beam and measurement results compared under the same environmental conditions. The accuracy level between National Reference Standard and clinical radiotherapy standard was found to be −1.92% and −2.02% for air kerma and absorbed dose to water respectively. To minimize the effect of error and maximize therapeutic dose during treatment in order to achieve required clinical outcome, calibration factor was determined for air kerma (Nk) as 49.7 mGy/nC and absorbed dose to water ND, as 52.9 mGy/nC. The study established that radiotherapy beam measurement chain is prone to errors. Hence there is a need to independently verify the accuracy of radiation dose to ensure precision of dose delivery. The errors must be accounted for during clinical planning by factoring in calibration factor to minimize the systematic errors during treatment, and thereby providing enough room to achieve ±5% dose delivery to tumor target as recommended by ICRU.
文摘目的:对常用4种新型进口及国产医用诊断X射线剂量仪的能量响应特性进行比较研究。方法:在国际原子能机构(IAEA)北京二级标准剂量学实验室(SSDL)的标准辐射场中,采用替代法分别完成10种管电压为60~150 k V、管电流为10 m A、用2.5 mm Al(毫米铝)做附加过滤的X射线诊断辐射线质进行比对测量。结果:国产RD-98诊断剂量仪与进口剂量仪的能量响应性能,在60~150 k V的X射线范围内,不同能量对剂量的响应均在±5%以内。结论:4种新型诊断X射线剂量仪的能量响应特性均良好,半导体探测器的诊断剂量仪与空气电离室剂量仪,不同能量对剂量的响应均符合国际电工委员会(IEC)的要求。