This paper posits that we are living in a computer simulation to simulate physical reality which has the same computer simulation process as virtual reality (computer-simulated reality). The computer simulation proces...This paper posits that we are living in a computer simulation to simulate physical reality which has the same computer simulation process as virtual reality (computer-simulated reality). The computer simulation process involves the digital representation of data, the mathematical computation of the digitized data in geometric formation and transformation in space-time, and the selective retention of events in a narrative. Conventional physics cannot explain physical reality clearly, while computer-simulated physics can explain physical reality clearly by using the computer simulation process consisting of the digital representation component, the mathematical computation component, and the selective retention component. For the digital representation component, the three intrinsic data (properties) are rest mass-kinetic energy, electric charge, and spin which are represented by the digital space structure, the digital spin, and the digital electric charge, respectively. The digital representations of rest mass and kinetic energy are 1 as attachment space for the space of matter and 0 as detachment space for the zero-space of matter, respectively, to explain the Higgs field, the reverse Higgs field, quantum mechanics, special relativity, force fields, dark matter, and baryonic matter. The digital representations of the exclusive and the inclusive occupations of positions are 1/2 spin fermion and integer spin boson, respectively, to explain spatial translation by supersymmetry transformation and dark energy. The digital representations of the allowance and the disallowance of irreversible kinetic energy are integral electric charges and fractional electric charges, respectively, to explain the confinements of quarks and quasiparticles. For the mathematical computation component, the mathematical computation involves the reversible multiverse and oscillating M-theory as oscillating membrane-string-particle whose space-time dimension (D) number oscillates between 11D and 10D and between 10D and 4D to explain cosmology. For the selective retention component, gravity, the strong force, electromagnetism, and the weak force are the retained events during the reversible four-stage evolution of our universe, and are unified by the common narrative of the evolution.展开更多
Ionic liquids(ILs) immobilized on silica as novel high performance liquid chromatography(HPLC)stationary phases have attracted considerable attention. However, it has not been applied to protein separation. In thi...Ionic liquids(ILs) immobilized on silica as novel high performance liquid chromatography(HPLC)stationary phases have attracted considerable attention. However, it has not been applied to protein separation. In this paper, N-methylimidazolium IL-modified silica-based stationary phase(Silpr Mim)was prepared and investigated as a novel multi-interaction stationary phase charged positively for protein separation. The results indicate that all of the basic proteins tested cannot be absorbed on this novel stationary phase, whereas all of the acidic proteins tested can be retained, and the baseline separation of eight kinds of acidic protein standards can be achieved when performed in reversed phase/ion-exchange chromatography(RPLC/IEC) mode. Compared with commonly used commercial octadecylated silica(ODS) column, the novel stationary phase can show selectivity and good resolution to acidic proteins, which has a promising application in the separation and analyses of acidic proteins from the complex samples in proteomics. In addition, the chromatographic behavior of proteins, the effect of the ligand structure and the retention mechanism on this stationary phase were also investigated.展开更多
文摘This paper posits that we are living in a computer simulation to simulate physical reality which has the same computer simulation process as virtual reality (computer-simulated reality). The computer simulation process involves the digital representation of data, the mathematical computation of the digitized data in geometric formation and transformation in space-time, and the selective retention of events in a narrative. Conventional physics cannot explain physical reality clearly, while computer-simulated physics can explain physical reality clearly by using the computer simulation process consisting of the digital representation component, the mathematical computation component, and the selective retention component. For the digital representation component, the three intrinsic data (properties) are rest mass-kinetic energy, electric charge, and spin which are represented by the digital space structure, the digital spin, and the digital electric charge, respectively. The digital representations of rest mass and kinetic energy are 1 as attachment space for the space of matter and 0 as detachment space for the zero-space of matter, respectively, to explain the Higgs field, the reverse Higgs field, quantum mechanics, special relativity, force fields, dark matter, and baryonic matter. The digital representations of the exclusive and the inclusive occupations of positions are 1/2 spin fermion and integer spin boson, respectively, to explain spatial translation by supersymmetry transformation and dark energy. The digital representations of the allowance and the disallowance of irreversible kinetic energy are integral electric charges and fractional electric charges, respectively, to explain the confinements of quarks and quasiparticles. For the mathematical computation component, the mathematical computation involves the reversible multiverse and oscillating M-theory as oscillating membrane-string-particle whose space-time dimension (D) number oscillates between 11D and 10D and between 10D and 4D to explain cosmology. For the selective retention component, gravity, the strong force, electromagnetism, and the weak force are the retained events during the reversible four-stage evolution of our universe, and are unified by the common narrative of the evolution.
基金supported by the National 863 Program(No.2006AA02Z227)Natural Science Foundation of Shaanxi Province(No.2011JZ002)+1 种基金the Foundation of Key Laboratory in Shaanxi Province(Nos.2010JS103,11JS097,14JS098)Shaanxi Provincial Science and Technology Co-ordinating innovation projects(No.2013SZS18-K01)
文摘Ionic liquids(ILs) immobilized on silica as novel high performance liquid chromatography(HPLC)stationary phases have attracted considerable attention. However, it has not been applied to protein separation. In this paper, N-methylimidazolium IL-modified silica-based stationary phase(Silpr Mim)was prepared and investigated as a novel multi-interaction stationary phase charged positively for protein separation. The results indicate that all of the basic proteins tested cannot be absorbed on this novel stationary phase, whereas all of the acidic proteins tested can be retained, and the baseline separation of eight kinds of acidic protein standards can be achieved when performed in reversed phase/ion-exchange chromatography(RPLC/IEC) mode. Compared with commonly used commercial octadecylated silica(ODS) column, the novel stationary phase can show selectivity and good resolution to acidic proteins, which has a promising application in the separation and analyses of acidic proteins from the complex samples in proteomics. In addition, the chromatographic behavior of proteins, the effect of the ligand structure and the retention mechanism on this stationary phase were also investigated.