Controllable step-flow growth of GaN on patterned freestanding substrate

A new kind of step-flow growth mode is proposed,which adopts sidewall as step source on patterned GaN substrate.The terrace width of steps originated from the sidewall was found to change with the growth temperature and ammonia flux.The growth mechanism is explained and simulated based on step motion model.This work helps better understand the behaviors of step advancement and puts forward a method of precisely modulating atomic steps.

基于TeamSTEPPS理论的案例情景教学法在急诊护理团队培训中的应用

急诊科具有危重患者多,突发状况多,医疗风险高等特点,目前国内大多数医院急诊科护士以团队形式开展工作,但临床工作中易出现职责分工不明确、配合不协调、组织抢救混乱等问题^([1])。团队培训是增强团队优质高效协作的重要途径^([2]),为进一步提升急诊护理团队协作,保障患者安全,本次研究将前期基于提高医疗质量和患者安全的团队策略与工具(team strategies and tools to enhance performance and patient safety,TeamSTEPPS)理论构建的急诊护理团队培训方案^([3])进行临床应用,取得了较好的效果。现报道如下。

"Five steps four quadrants" modularized en bloc dissection technique for accessing hepatic hilum lymph nodes in laparoscopic pancreaticoduodenectomy

BACKGROUND Although en bloc dissection of hepatic hilum lymph nodes has many advantages in radical tumor treatment,the feasibility and safety of this approach for laparo-scopic pancreaticoduodenectomy(LPD)require further clinical evaluation and investigation.AIM To explore the application value of the"five steps four quadrants"modularized en bloc dissection technique for accessing hepatic hilum lymph nodes in LPD patients.METHODS A total of 52 patients who underwent LPD via the"five steps four quadrants"modularized en bloc dissection technique for hepatic hilum lymph nodes from April 2021 to July 2023 in our department were analyzed retrospectively.The patients'body mass index(BMI),preoperative laboratory indices,intraoperative variables and postoperative complications were recorded.The relationships between preoperative data and intraoperative lymph node dissection time and blood loss were also analyzed.RESULTS Among the 52 patients,36 were males and 16 were females,and the average age was 62.2±11.0 years.There were 26 patients with pancreatic head cancer,16 patients with periampullary cancer,and 10 patients with distal bile duct cancer.The BMI was 22.3±3.3 kg/m²,and the median total bilirubin(TBIL)concentration was 57.7(16.0-155.7)µmol/L.All patients successfully underwent the"five steps four quadrants"modularized en bloc dissection technique without lymph node clearance-related complications such as postoperative bleeding or lymphatic leakage.Correlation analysis revealed significant associations between preoperative BMI(r=0.3581,P=0.0091),TBIL level(r=0.2988,P=0.0341),prothrombin time(r=0.3018,P=0.0297)and lymph node dissection time.Moreover,dissection time was significantly correlated with intraoperative blood loss(r=0.7744,P<0.0001).Further stratified analysis demonstrated that patients with a preoperative BMI≥21.9 kg/m²and a TIBL concentration≥57.7μmol/L had significantly longer lymph node dissection times(both P<0.05).CONCLUSION The"five steps four quadrants"modularized en bloc dissection technique for accessing the hepatic hilum lymph node is safe and feasible for LPD.This technique is expected to improve the efficiency of hepatic hilum lymph node dissection and shorten the learning curve;thus,it is worthy of further clinical promotion and application.

谐波驱动系统Back-stepping滑模控制研究

针对谐波传动系统动力学模型中存在的柔性变形、摩擦和运动误差等非线性因素。为了提高系统的传动精度,针对系统非线性刚度和静态误差因素进行了建模,并提出了一种Back-stepping滑模控制方法。利用Lyapunov稳定性理论,证明了闭环系统的误差是一致有界的。仿真结果表明,与PID控制相比,采用Back-stepping滑模控制,系统传动误差曲线峰峰值减小66.63%;负载端角速率误差曲线峰峰值减小77.35%。Back-stepping滑模控制能有效地补偿系统传动误差,抑制其负载端的速度波动,提高了系统的传动精度。

Performance improvement in stepped solar still modified by sponge layer

In this paper,the experimental investigation on the performance improvement of conventional stepped solar still is conducted.The steps are covered by the porous material to improve the performance of the conventional device and increase the evaporation rate.All the parameters,including the temperature on the glass surface,the water temperature inside the evaporation zone,and the amount of water produced in both conventional and modified stepped solar stills are measured and compared.The efficiency of two devices and their exergy efficiency have been calculated.Finally,the economic analysis of both devices has been done to check the economic feasibility of the modified device.The amount of freshwater generated during one day was 2244.4 and 3076.2 mL/m^(2),respectively for the conventional and modified stepped solar stills.As a result,the amount of water produced in one day by modified stepped solar still is 35.5% more than the conventional one.Also,the costs for the conventional and modified stepped solar stills have been calculated as 0.0359 and 0.029$/(L·m^(-2)),respectively.

Half-integer Shapiro steps in MgB_(2) focused He ion beam Josephson junctions

Half-integer microwave induced steps(Shapiro steps)have been observed in many different Josephson junction systems,which have attracted a lot of attention because they signify the deviation of current phase relation(CPR)and uncover many unconventional physical properties.In this article,we first report the discovery of half-integer Shapiro steps in MgB_(2)focused He ion beam(He-FIB)Josephson junctions.The half-integer steps'dependence on microwave frequency,temperature,microwave power,and magnetic field is also analyzed.We find that the existence of half-integer steps can be controlled by the magnetic field periodically,which is similar to that of high temperature superconductor(HTS)grain boundary junctions,and the similarity of the microstructures between gain boundary junctions and He-FIB junctions is discussed.As a consequence,we mainly attribute the physical origin of half-integer steps in MgB_(2)He-FIB junctions to the model that a He-FIB junction is analogous to a parallel junctions'array.Our results show that He-FIB technology is a promising platform for researching CPR in junctions made of different superconductors.

Transfer matrix method for free and forced vibrations of multi-level functionally graded material stepped beams with different boundary conditions

Functionally graded materials(FGMs)are a novel class of composite materials that have attracted significant attention in the field of engineering due to their unique mechanical properties.This study aims to explore the dynamic behaviors of an FGM stepped beam with different boundary conditions based on an efficient solving method.Under the assumptions of the Euler-Bernoulli beam theory,the governing differential equations of an individual FGM beam are derived with Hamilton’s principle and decoupled via the separation-of-variable approach.Then,the free and forced vibrations of the FGM stepped beam are solved with the transfer matrix method(TMM).Two models,i.e.,a three-level FGM stepped beam and a five-level FGM stepped beam,are considered,and their natural frequencies and mode shapes are presented.To demonstrate the validity of the method in this paper,the simulation results by ABAQUS are also given.On this basis,the detailed parametric analyses on the frequencies and dynamic responses of the three-level FGM stepped beam are carried out.The results show the accuracy and efficiency of the TMM.

Stability analysis of intermittently jointed rock slopes based on the stepped failure mode

In practical engineering,due to the noncontinuity characteristics of joints in rock slopes,in addition to plane failure,stepped sliding failure may occur for intermittently jointed rock slopes.Especially for intermittently bedding jointed rock slopes,the correlation and difference in strength parameters between joints and rock bridges,along with the various failure modes and intermittency of rock bridges,contribute to the complexity of stepped failure modes and the unpredictability of failure regions.Based on the upper-bound limit analysis method and multi-sliders step-path failure mode,considering the shear and tensile failure of rock bridges and the weakened relationship between the strength parameters of rock bridges and jointed surfaces,by introducing the modified M-C failure criterion and the formula for calculating the energy consumption of tensile failure of rock bridges,two failure mechanisms are constructed to obtain the safety factor(F_(s))of intermittently jointed rock slopes.The sequential quadratic programming method is used to obtain the optimal upper-bound solution for F_(s).The influence of multiple key parameters(slope height H,horizontal distance L,Slope angleβ,shear strength parameters of the rock bridgeφr and cr,Dimensionless parameter u,weakening coefficients of the internal friction angle and cohesion between the rock bridges and joint surfaces Kφand Kc)on the stability analysis of intermittently jointed rock slopes under the shear failure mode of rock bridges as well as under the tensile failure mode is also explored.The reliability of the failure mechanisms is verified by comparative analysis with theoretical results,numerical results,and landslide cases,and the variation rules of F_(s)with each key parameter are obtained.The results show that F_(s) varies linearly withφr and cr of the rock bridge and with K_(φ)and K_(c),whereas F_(s)changes nonlinearly with H and L.In particular,with the increase in Kφand Kc,Fs increases by approximately 52.78%and 171.02%on average,respectively.For rock bridge tensile failure,F_(s) shows a nonlinearly positive correlation withφr,cr,Kφand Kc.In particular,with the increase in Kφand Kc,Fs increases by approximately 13%and 61.69%on average,respectively.Fs decreases rapidly with increasing slope gradientβand decreasing dimensionless parameterμ.When Kφand Kc are both less than 1.0,the stepped sliding surface occurs more easily than the plane failure surface,especially in the case of tensile failure of the rock bridge.In addition,rock slopes with higher strength parameters,taller heights,and greater weakening coefficients are prone to rock bridge tension failure with lower Fs,and more attention should be given to the occurrence of such accidents in actual engineering.

A novel dynamic step size LMS optimization scheme for interference reducing in FBMC-QAM

Filter bank multicarrier quadrature amplitude modulation(FBMC-QAM)will encounter inter-ference and noise during the process of channel transmission.In order to suppress the interference in the communication system,channel equalization is carried out at the receiver.Given that the con-ventional least mean square(LMS)equilibrium algorithm usually suffer from drawbacks such as the inability to converge quickly in large step sizes and poor stability in small step sizes when searching for optimal weights,in this paper,a design scheme for adaptive equalization with dynamic step size LMS optimization is proposed,which can further improve the convergence and error stability of the algorithm by calling the Sigmoid function and introducing three new parameters to control the range of step size values,adjust the steepness of step size,and reduce steady-state errors in small step sta-ges.Theoretical analysis and simulation results demonstrate that compared with the conventional LMS algorithm and the neural network-based residual deep neural network(Res-DNN)algorithm,the adopted dynamic step size LMS optimization scheme can not only obtain faster convergence speed,but also get smaller error values in the signal recovery process,thereby achieving better bit error rate(BER)performance.

Contribution to the Full 3D Finite Element Modelling of a Hybrid Stepping Motor with and without Current in the Coils

The paper presents our contribution to the full 3D finite element modelling of a hybrid stepping motor using COMSOL Multiphysics software. This type of four-phase motor has a permanent magnet interposed between the two identical and coaxial half stators. The calculation of the field with or without current in the windings (respectively with or without permanent magnet) is done using a mixed formulation with strong coupling. In addition, the local high saturation of the ferromagnetic material and the radial and axial components of the magnetic flux are taken into account. The results obtained make it possible to clearly observe, as a function of the intensity of the bus current or the remanent induction, the saturation zones, the lines, the orientations and the magnetic flux densities. 3D finite element modelling provide more accurate numerical data on the magnetic field through multiphysics analysis. This analysis considers the actual operating conditions and leads to the design of an optimized machine structure, with or without current in the windings and/or permanent magnet.

以智慧启迪“完美贴合”的未来--对话雅视集团及STEPPER品牌高层

在追求舒适、精准的配戴体验之路上,从业者精进技艺、别出心裁,提出了多种创造性的解决方案,只为向完美更进一步。第三十五届中国国际眼镜业展览会上,雅视集团及旗下深圳司徕柏(光学)有限公司带来了STEPPER品牌的最新战略动向--STEPPER VISIONCARE,以及全新的AMOS(雅姆斯)智能系统,为行业呈现了其对极致舒适和精准视力保护的愿景。

TWO-STEP TRICK TO HACK INTO CELLS

In the microscopic world of viruses and human cells,a high-stakes game of lock-picking is constantly unfolding.In a recent study published in Cell on July 3,researchers from Fudan University,ShanghaiTech University,and the Institute of Biophysics(IBP)under the Chinese Academy of Sciences cracked the code on how one particular coronavirus,HCoV-HKU1,manages to sneak its way into our cells using a cunning two-step approach(doi:10.1016/j.cell.2024.06.016).

A Clean Switch Inner Mongolian town takes giant steps in transitioning to clean energy production

Staff at the Ruichen Wanniu Livestock Farm in Jungar Zhao Town,Jungar Banner,Inner Mongolia,are consistently busy,even during important festivals.

基于STEP模式下的计算机专业课堂实践教学效果提升策略

本研究的目的在于探讨基于STEP模式的计算机专业课堂实践教学效果提升策略。本研究采用了文献研究和理论分析的方法,探讨了STEP模式在计算机专业课堂中的优势,并提出了提升教学效果的策略。研究结果表明,STEP模式在计算机专业课堂实践教学中有利于跨学科整合、解决实际问题、促进团队协作。为了提高教学效果,本研究提出了多元化教学手段、师资队伍培训、及时更新理论教材等策略。本研究的结论是,采用STEP模式并实施相应策略可以有效提升计算机专业课堂实践教学的效果,帮助学生更好地适应现实问题解决和职业需求。

STEP教育模式下的环境设计课程探讨——以荆楚文化主题商业空间设计课程为例

随着社会对创新型人才需求的增加,STEP(Software, Theory, Experiment, Project)教育模式凭借其融合软件技能、理论知识、实验操作与项目管理的教学理念,为环境设计专业提供了新的教学策略。以荆楚文化主题的商业空间设计课程为例,概述了STEP教育模式的内涵,分析了环境设计专业课程实行STEP教学模式的必要性,探讨了基于STEP教学模式的商业空间设计课程实施路径。旨在提升学生的设计实践能力、强化文化理解力,有力支持环境设计专业的人才培养,促进地方文化与设计教育的有机结合。

产品模型数据交换标准STEP研究

在设计和制造中,许多系统过去常常要处理技术产品数据。每个系统有它自己的数据格式,所以相同的信息必然在多个系统中多次存储,这会导致了信息的冗余和错误。STEP是一个广泛使用的ISO标准(ISO10303),描述了表示和交换数字产品信息的方式。研究了STEP的标准体系结构,并研究不同应用对象的STEP和STEP未来的发展趋势。

IVUS引导下Step-Crush术治疗左主干分叉病变对支架贴壁情况及患者预后的影响

目的:分析血管内超声(IVUS)引导下Step-Crush术治疗左主干分叉病变对支架贴壁情况及患者预后的影响。方法:回顾分析2021年3月—2022年12月于九江市第一人民医院总院心血管内科就诊的左主干分叉病变患者60例,根据手术方式将患者分为IVUS组(n=34,采用IVUS引导下StepCrush术)和常规组(n=26,采用常规Step-Crush术)。对比两组支架情况(最大支架直径、左主干支架长度、支架贴壁不良发生率、支架边缘夹层发生率)、球囊参数(球囊最大直径、球囊最大压力)、心功能指标[左室射血分数(LVEF)、左室舒张末内径(LVEDD)]及心血管不良事件发生率。结果:相较于常规组,IVUS组最大支架直径、左主干支架长度、球囊最大直径均更长,球囊最大压力更大(P<0.05);术后2个月,IVUS组LVEF较常规组更高,LVEDD较常规组更低,差异均有统计学意义(P<0.05);IVUS组支架贴壁不良发生率、心血管不良事件发生率均更低,差异均有统计学意义(P<0.05)。两组支架边缘夹层发生率对比,差异无统计学意义(P>0.05)。结论:IVUS应用于Step-Crush术中可改善左主干分叉病变患者支架置入情况,降低支架贴壁发生率,有效预防心血管不良事件发生。

CMT Cycle Step工艺参数对焊缝表面特征纹路及成形尺寸的影响

采用CMT Cycle Step焊接工艺进行平板堆焊正交试验,研究了送丝速度、焊接速度、熔滴数量和间隔时间四个参数对焊缝表面特征纹路及成形尺寸的影响,建立了各参数与焊缝表面鱼鳞纹步长S、焊缝熔宽B、堆焊层厚度h之间的回归模型.结果表明,随着焊接速度、熔滴数量和间隔时间的增大,焊缝表面鱼鳞纹步长S呈逐渐增大的趋势.适当减小焊接速度和间隔时间,可有效减小焊缝表面高度差Δh,提高焊缝表面成形质量.随着送丝速度和熔滴数量的增大,焊缝熔宽B和堆焊层厚度h均逐渐增大;随着焊接速度的增大,焊缝熔宽B和堆焊层厚度h逐渐减小.根据理论分析和回归分析得到准确性较高的回归方程,为预测焊接焊缝成形以及优化焊接工艺参数提供理论依据.创新点:(1)系统研究了CMT Cycle Step焊接工艺参数对焊缝成形的影响规律,有助于采用该方法解决点焊、热敏感材料焊接、电弧增材制造等领域的相关技术难题.(2)建立了CMT Cycle Step焊接工艺的送丝速度、焊接速度、熔滴数量和间隔时间四个参数对焊缝表面特征纹路及成形尺寸回归模型,为预测焊缝成形以及优化焊接工艺参数提供理论依据.(3)对CMT Cycle Step焊缝表面特征纹路—鱼鳞纹进行量化评价,探究工艺参数对焊缝表面鱼鳞纹步长S和表面高度差Δh的影响规律,有利于获得高表面平整度的焊缝.

基于STEP工程教育理念的卓越工程师培养模式

为了适应新形势下卓越工程师人才培养的需求,在工程教育改革和工程认证大环境下,对标国际一流高校,借鉴CDIO等国内外先进的教育理念,并结合北京航空航天大学工程教育实际,提出了对支撑工程教育、培养卓越工程师具有普适性的STEP(即软件、理论、实验、项目)教育模式。STEP教育模式构建了项目驱动、理论教学与实验教学协同、软件工具支撑的课程体系,科教融合、虚实结合、竞赛聚合的教学模式,以及提升教学能力、完善实践环境、改进质量评价体系的保障机制。STEP教育模式已在北京航空航天大学相关学院部分课程建设中进行了推广和实践,并取得了良好的教学实践效果。

阿尔茨海默病细胞模型中β淀粉样蛋白介导ERK信号通路的STEP_(61)负性调控

背景:研究表明纹状体富集的酪氨酸磷酸酶61(striatal-enriched phosphatase,STEP_(61))在突触可塑性方面发挥重要作用。STEP位于后突触末端,影响突触增强的形成,可能的机制是使关键性信号蛋白如MAPK激酶ERK1/2去磷酸化并失活。目的:探讨STEP_(61)负性调控阿尔茨海默病细胞模型中β淀粉样蛋白介导的ERK信号通路的机制。方法:实验分3组,正常组为C57BL/6小鼠原代皮质神经元细胞;阿尔茨海默病细胞模型组是利用1μmol/L凝聚态的β淀粉样蛋白1-42加入皮质神经元细胞中1 h作为阿尔茨海默病细胞模型;β淀粉样蛋白1-42+RNAi组为在阿尔茨海默病细胞模型基础上,利用sRNAi技术制作STEP_(61)基因沉默组。应用Western Blot技术检测STEP_(61)的RNAi对ERK信号通路的影响。结果与结论:Western blot结果显示,阿尔茨海默病细胞模型组与正常组相比STEP_(61)蛋白表达增加了223%(P<0.05),使磷酸化STEP_(61)的比例减少到(75.6±4.6)%(P<0.05)。β淀粉样蛋白1-42+RNAi组STEP_(61)磷酸化的比例与阿尔茨海默病细胞模型组相比差异无显著性意义。同时阿尔茨海默病细胞模型组pE RK1/2的蛋白表达量较对照组减少(P<0.05),而β淀粉样蛋白1-42+RNAi组p ERK1/2的蛋白表达量较阿尔茨海默病细胞模型组显著增加(P<0.05)。结果说明:在阿尔茨海默细胞模型中证实了STEP_(61)调控β淀粉样蛋白介导的ERKs活性,并且很可能是通过脱磷酸化使他们失活而实现的。