Pyroelectricity effect on photoactivating palladium nanoparticles in PbTiO3 for Suzuki coupling reaction

Combining microwave radiation with photocatalytic systems is a promising method to inhibit photogenerated electron-hole recombination and enhance the photocatalytic reaction performance. In this study, we have designed Pd/Pb TiO3 catalysts that can use both microwave fields and photocatalysis. Benefiting from the synergistic effect of microwave field and UV light, the Pb TiO3 crystals convert thermal energy into electrical energy via the pyroelectricity effect, generating positive and negative charges(q+ and q-), while Pd nanoparticles significantly improve the quantum efficiency of the photocatalytic process. The composite catalyst significantly enhances the reaction rate and selectivity of the model Suzuki coupling reaction performed with bromobenzene. Microwave fields can directly act on chemical systems, promoting or changing various chemical reactions in unique ways.

Rapid synthesis of Pd single‐atom/cluster as highly active catalysts for Suzuki coupling reactions

Palladium(Pd)‐based catalysts are essential to drive high‐performance Suzuki coupling reactions,which are powerful tools for the synthesis of functional organic compounds.Herein,we developed a solution‐rapid‐annealing process to stabilize nitrogen‐mesoporous carbon supported Pd single‐atom/cluster(Pd/NMC)material,which provided a catalyst with superior performance for Suzuki coupling reactions.In comparison with commercial palladium/carbon(Pd/C)catalysts,the Pd/NMC catalyst exhibited significantly boosted activity(100%selectivity and 95%yield)and excellent stability(almost no decay in activity after 10 reuse cycles)for the Suzuki coupling reactions of chlorobenzenes,together with superior yield and excellent selectivity in the fields of the board scope of the reactants.Moreover,our newly developed rapid annealing process of precursor solutions is applied as a generalized method to stabilize metal clusters(e.g.Pd,Pt,Ru),opening new possibilities in the construction of efficient highly dispersed metal atom and sub‐nanometer cluster catalysts with high performance.

The Application of Suzuki Coupling Reaction on the Preparation of Carbosilane Dendrimers with 4-(Naphthalen-1-yl)phenyl Core

Carbosilane dendrimers with p-bromophenyl core were synthesized by alternating Grignard and hydrosilylation reaction. And the α-naphthalenyl was connected to the core by the Suzuki coupling reaction. A new carbosilane dendrimer with big π-conjugated structure [4-（naphthalen-l-yl）phenyl core] was given. It shows Suzuki coupling reaction is an effective and powerful core-functionalization method and the satisfactory result can be obtained through prolonging the reaction time with the increase of the generation of dendrimer.

Well-dispersed Palladium Nanoparticles Catalysts Prepared by Wood Nanomaterials for Suzuki Coupling Reaction

Herein, well-dispersed Palladium(Pd) nanoparticles(NPs) with good catalytic activities were prepared using a wood nanomaterial(WNM) as a reductant and a supporting agent. Various factors that influenced the NP morphologies, including reaction time, temperature, and precursor concentration were studied. The as-prepared Pd NPs/WNM showed good catalytic performance for Suzuki coupling reactions.

Synthesis of α-substituted β-amino acids via the Ni(II) complex through the Suzuki coupling reaction

A convenient and efficient method for the preparation of α-substituted β-amino acids has been developed by reacting compound 2 with various boric acid/borate 3 through Suzuki coupling reaction,which gave multiple structure types of substituted Ni（II） complexes 4 in high yields.Hydrogenation and hydrolysis of complexes 4 led to the corresponding α-substituted β-amino acids.

Highly efficient photocatalytic Suzuki coupling reaction by Pd_(3)P/CdS catalyst under visible-light irradiation

Monodispersed palladium phosphide(Pd_(3)P)(5.2 ± 0.5 nm) was firstly applied to photocatalytic Suzuki coupling reaction under visible light irradiation with CdS nanoflake as a photo sensitizer.This heterogeneous system exhibited high yields to corresponding products and excellent stability in alcohol solvent at room temperature.

Efficient imidazolium salts for palladium-catalyzed Mizoroki-Heck and Suzuki-Miyaura cross-coupling reactions

The system,Pd（OAc）_2/imidazolium salts（L_2）,was found as an efficient catalyst in the Heck coupling reaction of olefins with aryl halides and Suzuki reactions of various aryl halides with aryl boronic acids under aerobic condition.This catalytic system demonstrates great tolerance to a wide range of groups on all substrates of aryl halides,alkenes and aryl boronic acids.

Magnetically Separable and Versatile Pd/Fe3O4 Catalyst for Efficient Suzuki Cross-Coupling Reaction and Selective Hydrogenation of Nitroarenes

Magnetic nanoparticle-supported Pd/Fe3O4 was readily prepared and proved to be versatile catalyst for efficient Suzuki cross-coupling reaction, and the reduction of nitroarenes under mild conditions （balloon H2 pressure and room temperature）. The catalyst could be conveniently recovered and reused several times with sustained catalytic activity.

Stereoselective Synthesis of Novel C-Disaccharides via Suzuki Cross-Coupling Reaction

Novel β-C-disaccharides containing a three carbon linkage using exo-glycal as the precursor were prepared stereoselectively. The synthesis was achieved by the tandem reactions of the stereoselective hydroboration of exo-glycal and Suzuki cross-coupling reaction with an iodovinyl sugar, and followed by hydrogenated deprotection under the catalysis of Pd（OH）2/C.

Synthesis of cycloparaphenylene under spatial nanoconfinement

Suzuki coupling reactions between symmetrical monomers were conducted in various mesoporous silica nanoreactors grafted with palladium catalysts,enabling the selective formation of[12]cycloparaphenylene precursor with separate yield up to 25%in one-pot reactions,much higher than that in homogeneous reaction.The spatial nanoconfinement of the nanoreactors promotes the macrocyclization while limits the concomitant linear oligomer formation,offering more possibilities for the synthesis of macrocycles from symmetrical monomers in one-pot reaction.

Solid-Phase Organic Synthesis of Aryl Vinyl Ethers Using Sulfone-Linking Strategy

A novel facile solid-phase organic synthesis of aryl vinyl ethers by reaction of polystyrene-supported 2-phenylsulfonylethanol with phenols under Mitsunobu conditions and subsequent elimination reaction with DBU has been developed. The advantages of this method include straightforward operation, good yield and high purity of the products. Alternatively, a typical example of Suzuki coupling reaction on-resin was further applied to prepare 4-phenylphenyl vinyl ether for extending this method.

A Facile Synthesis of Enantiomerically Pure （R）-6-Arylbinols

This work reported a convenient method for the preparation of enantiomerically pure 6-aryl-2,2＇-dihydroxy-1, l＇- binaphthyl derivatives starting from the commercially available （R）-2,2＇-hydroxy-l, l＇-binaphthyl [（R）-I] via bromi- nation, hydrolysis and Suzuki cross coupling reaction. This novel synthetie method was characterized with high re- gioselectivity, simple operation, mild reaction conditions, and excellent yield （up to 73%）. On the other hand, we synthesized the target unknown compounds, which were confirmed by IR, 1H NMR, 13C NMR, MS and elementary analysis.

First synthesis and in vitro biological assessment of isosideroxylin,6,8-dimethylgenistein and their analogues as nitric oxide production inhibition agents

A modular and efficient synthesis of the biologically significant C-methylisoflavones isosideroxylin（1）,6,8-dimethylgenistein（2） and their analogues（3-8） is established for the first time.The synthesis is realized in 7-8 steps in overall yields of 16%-24%from commercially inexpensive phloroglucinol and features a high yielding Vilsmeier-Haack reaction,Friedel-Crafts acylation,Gammill＇s protocol and Suzuki coupling as the pivotal transformations.Next,these compounds evaluated for their inhibitory potency on the production of nitric oxide（NO） in lipopolysaccharide（LPS）-activated RAW-264.7 cells as an indicator of anti-inflammatory activity.The results showed that all the compounds decreased NO production in a dose-dependent manner without marked cytotoxicity and IC_（50） values are found in the range of 10.17-33.88 μmol/L.Of note,compounds 3 followed by 1,7 and 8 show comparable inhibitory activity with positive control（N-monomethyl-L-arginine,L-NMMA）.