期刊文献+
共找到7篇文章
< 1 >
每页显示 20 50 100
烙铁头蛇毒血小板聚素(TMVA)对动物体内血小板的聚集与止血功能
1
作者 熊郁良 杨长久 +1 位作者 王婉瑜 杨上川 《Zoological Research》 SCIE CAS 1987年第S01期23-31,共9页
兔子实验表明静脉注射TMVA后血小板数量降低70%以上,3小时后回升,12小时左右接近正常。经注射TMVA后PF_(3),PF_(4)活性增强,出血时间缩短,全血凝固时间也略有缩短,在不同时间内取心脏血测定结果证明血小板聚集功能降低,低剂量组呈波浪... 兔子实验表明静脉注射TMVA后血小板数量降低70%以上,3小时后回升,12小时左右接近正常。经注射TMVA后PF_(3),PF_(4)活性增强,出血时间缩短,全血凝固时间也略有缩短,在不同时间内取心脏血测定结果证明血小板聚集功能降低,低剂量组呈波浪状变化,24小时尚未恢复正常。经对给药后兔子24小时及30天的病理切片检查发现仅个别动物有血栓,血小板聚集和红细胞沉积。小白鼠腹腔注射TMVA后,出血时间也明显缩短,而大剂量组5小时后出血时间略有延长。 展开更多
关键词 烙铁头蛇毒血小板聚集素 血小板第3 第4因子 ADP途径 TXB_(2)途径 血栓
下载PDF
烙铁头蛇毒血小板聚集素作为筛选抗血小板药物的模式初探
2
作者 马国义 张子昭 陈植和 《Zoological Research》 SCIE CAS 1987年第S01期47-50,共4页
本文利用烙铁头蛇毒血小板聚集素(TMVA)作为筛选抗血小板药的工具,对三种中草药有效成分普罗托品,三七叶总皂甙和珠子参总皂甙进行了筛选,并与ADP模式相比较。结果发现普罗托品及珠子参总皂甙对ADP及TMVA诱导的家兔血小板聚集均有抑制作... 本文利用烙铁头蛇毒血小板聚集素(TMVA)作为筛选抗血小板药的工具,对三种中草药有效成分普罗托品,三七叶总皂甙和珠子参总皂甙进行了筛选,并与ADP模式相比较。结果发现普罗托品及珠子参总皂甙对ADP及TMVA诱导的家兔血小板聚集均有抑制作用;而三七叶总皂甙则只能抑制ADP诱导的家兔血小板聚集,不能抑制TMVA诱导的家兔血小板聚集。普罗托品抑制ADP及TMVA诱导家兔血小板聚集的IC;分别为26.85±10.07μM和38.04±12.11μM。珠子参总皂甙(2mg/ml)抑制ADP及TMVA诱导的家兔血小板聚集的最大抑制率分别为51.7±4.7和50.3±4.7%。三七叶总皂甙(3mg/ml)抑制ADP诱导家兔血小板聚集的最大抑制率为44.8±4.7%。 展开更多
关键词 普罗托品 三七叶总皂甙 珠子参总皂甙 血小板聚集 烙铁头蛇毒血小板聚集素
下载PDF
毛冬青甲素对血小板和血管内皮细胞功能的影响 被引量:1
3
作者 蔺桂芬 杨涛 《生理科学》 CSCD 1989年第1期42-45,共4页
毛冬青甲素对ADP及AA活化血小板功能的二条途径有抑制作用。本文证明毛冬青甲素对活化血小板的第三条途径TMVA也有抑制作用。提示毛冬青甲素为一广谱抗血小板药,并可抑制丙二醛的生成,但不具有刺激人工培养人脐静脉内皮细胞生成前列环... 毛冬青甲素对ADP及AA活化血小板功能的二条途径有抑制作用。本文证明毛冬青甲素对活化血小板的第三条途径TMVA也有抑制作用。提示毛冬青甲素为一广谱抗血小板药,并可抑制丙二醛的生成,但不具有刺激人工培养人脐静脉内皮细胞生成前列环素的能力。 展开更多
关键词 毛冬青甲素 血小板 血管内皮细胞
下载PDF
A novel discrimination method for neutrinos and cosmogenic isotopes in liquid scintillator-based detectors
4
作者 Xin Zhang Haoqi Lu +2 位作者 Changgen Yang Zeyuan Yu Yaoguang Wang 《Radiation Detection Technology and Methods》 CSCD 2024年第3期1448-1460,共13页
Purpose Cosmogenic isotopes,known for their diverse types and relatively long lifetimes,are frequently treated as significant backgrounds in neutrino experiments.Particularly in the correlation events of inverse beta ... Purpose Cosmogenic isotopes,known for their diverse types and relatively long lifetimes,are frequently treated as significant backgrounds in neutrino experiments.Particularly in the correlation events of inverse beta decay(IBD)events of reactor neutrinos,addressing and removing'Li and 8He background is necessary.Similarly,for elastic scattering(ES)events of solar neutrinos,isotopes such as 12B and°Li have significant impacts.This study aims to identify an appropriate method for reducing the backgrounds in neutrino experiments.Methods In this paper,we conducted simulations of muon backgrounds in a liquid scintillator detector using Geant4 and explored the correlation between cosmogenic isotopes and muons.We introduced a novel method to distinguish cosmogenic isotopes from neutrino signals.Utilizing the relationship between the distance and time of spallation isotopes to muons and neutrons,we employed the TMVA(tools for multi-variable analysis)to distinguish neutrino signals from isotope backgrounds,achieving good performance.Results Compared with the traditional veto method,the efficiency has been improved by 1%for correlated events and 18%for single-event signals at the same background level.Conclusion This study presents a novel method for discriminating cosmogenic isotopic backgrounds,achieving a higher signal-to-noise ratio compared to traditional approaches,and showing good potential applicability to similar analyses in the future. 展开更多
关键词 tmva Neutrino detector Cosmogenic isotopes EFFICIENCY
原文传递
Expected energy spectrum of cosmic ray protons and helium below4 PeV measured by LHAASO 被引量:1
5
作者 L.Q.Yin S.S.Zhang +8 位作者 Z.Cao B.Y.Bi C.Wang J.L.Liu L.L.Ma M.J.Yang Y.Zhang Z.Y.You Z.Z.Zong 《Chinese Physics C》 SCIE CAS CSCD 2019年第7期86-96,共11页
The Large High Altitude Air Shower Observatory(LHAASO) is a composite cosmic ray observatory consisting of three detector arrays: kilometer square array(KM2 A), which includes the electromagnetic detector array and mu... The Large High Altitude Air Shower Observatory(LHAASO) is a composite cosmic ray observatory consisting of three detector arrays: kilometer square array(KM2 A), which includes the electromagnetic detector array and muon detector array, water Cherenkov detector array(WCDA) and wide field-of-view Cherenkov telescope array(WFCTA). One of the main scientific objectives of LHAASO is to precisely measure the cosmic rays energy spectrum of individual components from 10^14 eV to 10^18 eV. The hybrid observation will be employed by the LHAASO experiment, in which the lateral and longitudinal distributions of extensive air shower can be observed simultaneously. Thus, many kinds of parameters can be used for primary nuclei identification. In this paper, high purity cosmic ray simulation samples of the light nuclei component are obtained using multi-variable analysis. The apertures of 1/4 LHAASO array for pure proton and mixed proton and helium(H&He) samples are 900 m^2 Sr and1800 m^2 Sr, respectively. Prospect of obtaining proton and H&He spectra from 100 TeV to 4 PeV is discussed. 展开更多
关键词 LHAASO hybrid measurement energy SPECTRUM COMPOSITION tmva
原文传递
Discrimination of converted photons and neutral pions at high energies
6
作者 肖虹 陈国明 +14 位作者 陶军全 卞建国 范嘉伟 梁松 孟祥伟 沈玉乔 唐志成 王健 王健 汪先友 王征 徐明 许伟伟 杨民 严琪 《Chinese Physics C》 SCIE CAS CSCD 2012年第10期979-984,共6页
In the LHC experiment, the H →γγ channel provides a clean final state with an effective mass peak that is reconstructed with great precision, despite the small branching ratio. As a consequence, the H →γγ channe... In the LHC experiment, the H →γγ channel provides a clean final state with an effective mass peak that is reconstructed with great precision, despite the small branching ratio. As a consequence, the H →γγ channel is one of the most promising channels for the Higgs discovery in the very low mass region. In order to increase the sensitivity of the Higgs search, background rejection rate is very important, so γ/π 0 discrimination is one of the key points in the analysis. At least 40% of photons will convert with the experience of ATLAS and CMS. We constructed electromagnetic calorimeter (ECAL) in GEANT4 simulation, using 6 variables which have different shapes between converted γ and π 0 , with the TMVA (Toolkit for Multivariate Data Analysis) to do the separation. With this method we can get 30% to 60% π 0 rejection efficiency when keeping 90% converted γ efficiency, in the region of transverse momentum 15 GeV to 75 GeV, not only in MC sumulation but also in real data. 展开更多
关键词 converted γ π 0 DISCRIMINATION tmva
原文传递
几种物质对不同诱导剂诱导的全血血小板聚集的影响
7
作者 李树清 王婉瑜 《中华血液学杂志》 CAS CSCD 北大核心 1991年第2期90-91,共2页
关键词 血小板 阻抗法 tmva
原文传递
上一页 1 下一页 到第
使用帮助 返回顶部