Geometric regulation of collective cell tangential ordering migration

Collective cell migration is a coordinated movement of multi-cell systems essential for various processes throughout life.The collective motions often occur under spatial restrictions,hallmarked by the collective rotation of epithelial cells confined in circular substrates.Here,we aim to explore how geometric shapes of confinement regulate this collective cell movement.We develop quantitative methods for cell velocity orientation analysis,and find that boundary cells exhibit stronger tangential ordering migration than inner cells in circular pattern.Furthermore,decreased tangential ordering movement capability of collective cells in triangular and square patterns are observed,due to the disturbance of cell motion at unsmooth corners of these patterns.On the other hand,the collective cell rotation is slightly affected by a convex defect of the circular pattern,while almost hindered with a concave defect,also resulting from different smoothness features of their boundaries.Numerical simulations employing cell Potts model well reproduce and extend experimental observations.Together,our results highlight the importance of boundary smoothness in the regulation of collective cell tangential ordering migration.

The tangential k-Cauchy-Fueter type operator and Penrose type integral formula on the generalized complex Heisenberg group

The tangential k-Cauchy-Fueter operator and k-CF functions are counterparts of the tangential Cauchy–Riemann operator and CR functions on the Heisenberg group in the theory of several complex variables,respectively.In this paper,we introduce a Lie group that the Heisenberg group can be imbedded into and call it generalized complex Heisenberg.We investigate quaternionic analysis on the generalized complex Heisenberg.We also give the Penrose integral formula for k-CF functions and construct the tangential k-Cauchy-Fueter complex.

Viscoelastic Burger’s model for tunnels supported with tangentially yielding liner

This study proposed an analytical model for the tunnel supported with a tangentially yielding liner in viscoelastic ground.The efficiency of the developed analytical model was verified by comparing the calculated results with associated numerical simulation results.Using the analytical model,a comprehensive parameter sensitivity analysis was performed to examine the effects of the rate of tunnel face advancement,concrete liner thickness,installation time of liner,and strength and thickness of yielding elements on the tunnel responses.The results highlight the significant benefit of the tangentially yielding liner to relieve overstress in the tunnel liner and improve the stability of the tunnel.The yield efficiency of the tangentially yielding liner depends highly on the yielding strength and deformable capacity of the yielding elements and less on the installation time.

Method of SLAS’s ground track manipulation based on tangential impulse thrust

Satellites with altitudes below 400 km are called super low altitude satellites(SLAS),often used to achieve responsive imaging tasks.Therefore,it is important for the manipulation of its ground track.Aiming at the problem of ground track manipulation of SLAS,a control method based on tangential impulse thrust is proposed.First,the equation of the longitude difference between SLAS and the target point on the target latitude is derived based on Gauss’s variational equations.On this basis,the influence of the tangential impulse thrust on the ground track’s longitude is derived.Finally,the method for ground track manipulation of SLAS under the tangential impulse thrust is proposed.The simulation results verify the effective-ness of the method,after manipulation,the satellite can visit the target point and revisit it for multiple days.

Study on the Tangential Tensile Mechanical Properties of Moso Bamboo

In this work,we used tensile tests to analyze the tangential failure forms of raw bamboo and determine a relationship between tangential tensile strength,elastic modulus,position,density,and moisture content.We found that the tangential mechanical properties of the culm wall were mainly dependent on the mechanical properties of the basic structure of the thin wall.Formulas for calculating the tangential tensile strength of moso bamboo and adjusting the moisture content were also determined.The tangential tensile strength and the tangential tensile modulus of elasticity(TTMOE)followed:outer>middle>inner,and diaphragm>bamboo node>culm wall.Below the fiber saturation point,the tangential tensile strength and TTMOE values of the bamboo gradually decreased with increasing moisture content.When the moisture content was 15%,the tangential tensile strengths of the inner,middle,outer,culm wall,bamboo node,and diaphragm samples of the five-year-old moso bamboo were 3.17,3.29,3.31,3.24,3.67,and 8.85 MPa,respectively.Furthermore,their TTMOE values were 215.09,227.98,238.45,224.04,267.21,and 559.27 MPa,respectively.Hence,this study provides a theoretical basis for future research on bamboo cracking.

Modeling and Simulation Study on Reverse Swirl of Secondary Air in Large Tangentially Fired Boiler

Based on the porosity method and the improved non uniform QUICK scheme, this paper describes a three dimensional computer simulation to predict the flow characteristics in a tangentially fired boiler. The model is applied to a 600?MW boiler modeling under different operating conditions of reverse swirl of secondary air. The numerical results achieve reasonable agreement with experimental data. The calculated results of flow field, the pressure distribution, the relative diameter of tangential circle, angular momentum flux in furnace and the velocity distribution index in horizontal gas pass are analyzed in detail. And then the effects of the reverse swirl of secondary air on flue gas imbalance are discussed. Finally a reasonable operating condition of the reverse swirl of secondary air is presented.

Upper bound solution for supporting pressure acting on shallow tunnel based on modified tangential technique

Based on the nonlinear failure criterion and the upper bound theorem, the modified tangential technique method was proposed to derive the expression of supporting pressure acting on shallow tunnel. Instead of the same stress state, different normal stresses on element boundaries were used. In order to investigate the influence of different factors on supporting pressures, the failure mechanism was established. The solution of supporting pressure, with different parameters, was obtained by optimization theory. The corresponding failure mechanism and numerical results were presented. In comparison with the results using the single tangential technique method, it is found that the proposed method is effective, and the good agreement shows that the present solution of supporting pressure is reliable.

A Tangential Wind Profile for Simulating Strong Tropical Cyclones with MM5

A new tangential wind profile for simulating strong tropical cyclones is put forward and planted into the NCAR- AFWA tropical cyclone bogussing scheme in MM5. The scheme for the new profile can make full use of the information from routine typhoon reports, including not only the maximum wind, but also the additional information of the wind speeds of 25.7 and 15.4 ms-1 and their corresponding radii, which are usually provided for strong cyclones. Thus, the new profile can be used to describe the outer structure of cyclones more accurately than by using the earlier scheme of MM5 in which on- ly the maximum wind speed is considered. Numerical experimental forecasts of two strong tropical cyclones are performed to examine the new profile. Results show that by using the new profile the prediction of both cyclones’ intensity can be obvi- ously improved, but the effects on the track prediction of the two cyclones are different. It seems that the new profile might be more suitable for strong cyclones with shifted tracks. However, the conclusion is drawn from only two typhoon cases, so more cases are needed to evaluate the new profile.

Characterization of Stress Concentration by Tangential Component Hp(x) of Metal Magnetic Memory Signals

The correlation between the stress concentration and the spontaneous magnetic signals of metal magnetic memory(MMM) was investigated via tensile tests. Sheet specimens of the Q235 steel were machined into standard bars with rectangular holes to obtain various stress concentration factors. The tangential component Hp(x) of MMM signals and its related magnetic characteristic parameters throughout the loading process were presented and analyzed. It is found that the tangential component Hp(x) is sensitive to the abnormal magnetic changes caused by the local stress concentration in the defect area. The minimum magnetic field is positively correlated to the magnitude of the load and the distance from the notch. The tangential magnetic stress concentration factor presents good numerical stability during the entire loading process, and can be used to evaluate the stress concentration factor. The results obtained will be a complement to the MMM technique.

A MODEL FOR COMPUTATIONAL INVESTIGATION OF ELASTO-PLASTIC NORMAL AND TANGENTIAL CONTACT CONSIDERING ADHESION EFFECT

With the rapid development of Micro-Electro-Mechanical System(MEMS),we enter a field in which the surface effects have dominated many of the micro-scale phenomena,and the adhesive contact is one of the focuses.In this paper,a feasible model for finite element computation is presented via a macroscopic and microscopic combination approach,in which the adhesive forces are simulated by some non-linear spring elements considering the softening stage.Two basic problems concerning the adhesion effect were considered;through specific quantitative analysis,the results show a consistency with the current elastic continuum theories of adhesion and a brief investigation into the effects of adhesion on plastic deformation and tangential contact will be carried out as well.

Influence of the earth rotation on the interfacial wave solutions and wave-induced tangential stress in a two-layer fluid system

Interfacial waves and wave-induced tangential stress are studied for geostrophic small amplitude waves of two-layer fluid with a top free surface and a fiat bottom. The solutions were deduced from the general form of linear fluid dynamic equations of two-layer fluid under the f-plane approximation, and wave-induced tangential stress were estimated based on the solutions obtained. As expected, the solutions derived from the present work include as special cases those obtained by Sun et al. （2004. Science in China, Ser. D, 47（12）： 1147-1154） for geostrophic small amplitude surface wave solutions and wave-induced tangential stress if the density of the upper layer is much smaller than that of the lower layer. The results show that the interface and the surface will oscillate synchronously, and the influence of the earth＇s rotation both on the surface wave solutions and the interfacial wave solutions should be considered.

Computational Modeling of Tangentially Fired Boiler(Ⅱ) NO_x Emissions

The paper describes numerical and experimental study on reduction of NOx emissions in a 600 MW tangentially fired boiler furnace under different operating conditions. A simplified NOX formation mechanism model, along with the gas-particle multiphase flow model, is adopted. The prediction yields encouraging results as compared to experimental data.

THRFuzzy:Tangential holoentropy-enabled rough fuzzy classifier to classification of evolving data streams

The rapid developments in the fields of telecommunication, sensor data, financial applications, analyzing of data streams, and so on, increase the rate of data arrival, among which the data mining technique is considered a vital process. The data analysis process consists of different tasks, among which the data stream classification approaches face more challenges than the other commonly used techniques. Even though the classification is a continuous process, it requires a design that can adapt the classification model so as to adjust the concept change or the boundary change between the classes. Hence, we design a novel fuzzy classifier known as THRFuzzy to classify new incoming data streams. Rough set theory along with tangential holoentropy function helps in the designing the dynamic classification model. The classification approach uses kernel fuzzy c-means(FCM) clustering for the generation of the rules and tangential holoentropy function to update the membership function. The performance of the proposed THRFuzzy method is verified using three datasets, namely skin segmentation, localization, and breast cancer datasets, and the evaluated metrics, accuracy and time, comparing its performance with HRFuzzy and adaptive k-NN classifiers. The experimental results conclude that THRFuzzy classifier shows better classification results providing a maximum accuracy consuming a minimal time than the existing classifiers.

SYMMETRIC FORMULATION OF TANGENTIAL STIFFNESSES FOR NON-ASSOCIATED VISCOPLASTICITY WITH AN IMPLICIT TIME INTEGRATION SCHEME

A numerical scheme is presented which enables the use of symmetric equation solvers in tangential stiffness programs for non-associated viscoplastic materials.

THE TOPOGRAPHIC PARAMETER SENSITIVITY TO VORTICITY PROPAGATION AND TYPHOON TANGENTIAL VELOCITY CHANGES

A high resolution shallow-water model is designed to study the roles which the topographical parameter and latitudinal basic flow play in the propagation of vortex Rossby waves and typhoon tangential velocity changes. With no latitudinal flow, the horizontal scale effects of island terrain on the vortex Rossby waves propagation show that the disturbance vorticity follows a clockwise island-circulating path more significantly, the local maximum wind speed amplitude reduces more sharply, the maximum mean azimuthally tangential wind spins down more substantially, when the topographic horizontal scale augments. With the latitudinal basic flow, the evolution of local wind and mean velocity are affected by the distance changes between TC and the terrain and the time length of topographic action: the local wind amplitude intensifies and the mean velocity diminishes while the distance is shortening; the opposite is true while TC is away from the terrain gradually.

Computational Modeling of Tangentially Fired Boiler (I) Models, Flow Field and Temperature Profiles

In this work, an Eulerian/Lagrangian approach has been employed to investigate numerically the flow characteristics, heat transfer and combustion in a tangentially fired furnace. The RNG (Re-normalization group) k-ε model and a new method for cell face velocity interpolation based on a non-staggered grid system are employed. To avoid pseudo-diffusion that is significant in modeling tangentially fired furnaces, attempts are made at improving the differential volume scheme. Some new developments on turbulent diffusion of particles are also taken into account. Thus, computational accuracy is improved substantially.

The Tangential Force Distribution on Inner Cylinder of Power Law Fluid Flowing in Eccentric Annuli with the Inner Cylinder Reciprocating Axially

Based on the governing equations of the inner cyinder of the unsteady flow of the power law fluid in eccentric annuli with the inner cylinder reciprocating axially in bipolar coordinate system, the calculation formulae of tangential force were established, and the relevant numerical calculation method was given. Taking the aqueous solution of partially hydrolyzed polyacrylamides (HPAM) for examples, the tangential forces were calculated by using the formulae and numerical calculation method mentioned above;the curves of the tangential force on the wall of the inner cylinder of HPAM aqueous solution were plotted;and the effects on the tangential force of the flow behavior index of the power law fluid, the stroke and the stroke frequency of the inner cylinder were analyzed.

Tangential stress analysis of myocardial wall by finite element method

A novel method is presented to build the triangular surface model and calculate the tangential stress and strain of myocardial wall ,which can be further used to reflect the left ventricle twisting—a sensitive index to assess the systolic and diastolic function of heart. Firstly, a point distribution model is used to obtain the feature points of the ventricular surface in medical images. Secondly, the surface model is constructed by triangular mesh, and then the subdivision strategy is introduced to refine the model. Thirdly, plane projection and finite element method(FEM) are applied to calculate the tangential stress and strain.Finally, the distribution of tangential modulus of elasticity is discussed. The stimulation results show that the proposed method can be used to compute the tangential stress and strain of myocardial wall effectively and the computing result is consistent with the results mentioned in the literatures.

A Quantitative Analysis of Dose Distributions of Two Tangential Whole Breast Irradiation Techniques

We compared DVHs （dose volume histograms） of two tangential irradiation techniques for whole breast RT （radiotherapy） CT （computed tomography） based 2D （two dimensional） technique with wedge filters and 3D CRT （three dimensional conformal radiotherapy） with segmented fields. These two modalities are commonly used in external beam radiotherapy of breast cancer in Clinical Center Nis, Clinic of Oncology, Serbia. Therapy plans that employed two techniques were generated for eighteen patients. Dosimetric outcomes of each technique were investigated. The maximum dose of breast CTV was significantly reduced from 55.83 Gy for 2D to 54.1 Gy for 3D CRT. Also, the maximum dose of lung tissue decreased from 51.81 Gy for 2D to 49.61 Gy for 3D. The dose conformity and uniformity were much better with 3D CRT segmented field technique.

Simulation Analysis of Flow Characteristics in the Vortex Diode with Double Tangential Tube

The paper analyzed flow characteristics in vortex diode with double tangential tube by numerical simulation. Compared to traditional vortex diode with one tangential tube, the structure of double tangential tube can reduce the forward resistance and improve overall performance. The symmetrical design adopted in vortex diode with double tangential tube;the internal flow field in chamber showed symmetrical distribution in the reverse flow, which can improve the flow stability and accelerate the convergence speed in simulation.